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by Morrissy, A. Sorana and Cavalli, Florence M. G and Remke, Marc and Ramaswamy, Vijay and Shih, David J. H and Holgado, Borja L and Farooq, Hamza and Donovan, Laura K and Garzia, Livia and Agnihotri, Sameer and Kiehna, Erin N and Mercier, Eloi and Mayoh, Chelsea and Papillon-Cavanagh, Simon and Nikbakht, Hamid and Gayden, Tenzin and Torchia, Jonathon and Picard, Daniel and Merino, Diana M and Vladoiu, Maria and Luu, Betty and Wu, Xiaochong and Daniels, Craig and Horswell, Stuart and Thompson, Yuan Yao and Hovestadt, Volker and Northcott, Paul A and Jones, David T. W and Peacock, John and Wang, Xin and Mack, Stephen C and Reimand, Jüri and Albrecht, Steffen and Fontebasso, Adam M and Thiessen, Nina and Li, Yisu and Schein, Jacqueline E and Lee, Darlene and Carlsen, Rebecca and Mayo, Michael and Tse, Kane and Tam, Angela and Dhalla, Noreen and Ally, Adrian and Chuah, Eric and Cheng, Young and Plettner, Patrick and Li, Haiyan I and Corbett, Richard D and Wong, Tina and Long, William and Loukides, James and Buczkowicz, Pawel and Hawkins, Cynthia E and Tabori, Uri and Rood, Brian R and Myseros, John S and Packer, Roger J and Korshunov, Andrey and Lichter, Peter and Kool, Marcel and Pfister, Stefan M and Schüller, Ulrich and Dirks, Peter and Huang, Annie and Bouffet, Eric and Rutka, James T and Bader, Gary D and Swanton, Charles and Ma, Yusanne and Moore, Richard A and Mungall, Andrew J and Majewski, Jacek and Jones, Steven J. M and Das, Sunit and Malkin, David and Jabado, Nada and Marra, Marco A and Taylor, Michael D
Nature Genetics, ISSN 1061-4036, 05/2017, Volume 49, Issue 5, pp. 780 - 788
Spatial heterogeneity of transcriptional and genetic markers between physically isolated biopsies of a single tumor poses major barriers to the identification... 
IN-VITRO | EVOLUTION | SOLID TUMORS | SUBTYPES | INTRATUMOR HETEROGENEITY | GROWTH | GENETICS & HEREDITY | EXPRESSION | RENAL-CELL CARCINOMA | T-CELLS | LYMPHOCYTES | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Transcriptome | Child, Preschool | Male | INDEL Mutation | DNA Copy Number Variations | Medulloblastoma - pathology | Aged, 80 and over | Adult | Female | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Child | Principal Component Analysis | Genome-Wide Association Study | Gene Expression Profiling - methods | Cerebellar Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | Genetic Heterogeneity | Aged | Polymorphism, Single Nucleotide | Mutation | Cluster Analysis | Brain | Gene mutations | Biopsy | Medulloblastoma | Genetic aspects | Diagnosis | Health aspects | Methods | Pediatrics | Laboratories | Neuropathology | Brain cancer | Colleges & universities | Oncology | Genomes | Biology | Neurosurgery | Consortia | Heterogeneity | Immunology | Renal cell carcinoma | Genetics | Bioindicators | Research centers | Medical research | Hematology | Gene expression | Children & youth | Genetic markers | Hospitals | Glioma | Biomarkers | Tumors | Index Medicus | Spatial heterogeneity | glioblastoma multiforme | renal cell carcinoma | gene expression profiling | medulloblastoma | whole exome sequencing
Journal Article
CELL CYCLE, ISSN 1538-4101, 10/2007, Volume 6, Issue 19, pp. 2332 - 2338
Breast tumors are composed of a variety of cell types with distinct morphologies and behaviors. It is not clear how this tumor heterogeneity comes about. Two... 
ADULT HUMAN BREAST | PROGENITOR CELLS | INTRATUMORAL HETEROGENEITY | SOLID TUMORS | breast cancer | POPULATION ANALYSES | CANCER STEM-CELLS | CELL BIOLOGY | clonal evolution | OLD IDEA | cancer stem cells | PROGRESSION | tumor heterogeneity | IN-VITRO PROPAGATION
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The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 10, pp. 956 - 957
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2011, Volume 121, Issue 10, pp. 3786 - 3788
Journal Article
Science, ISSN 0036-8075, 4/2012, Volume 336, Issue 6079, pp. 304 - 305
All cells are almost perfect copies of prior cells. Imperfect DNA replication creates random variation, which is the substrate for evolution. Such differences... 
Chemotherapy | Genomics | PERSPECTIVES | Cell division | Evolution | Kidney cells | Genomes | Genetic mutation | Genetic heterogeneity | Tumors | Cancer | EVOLUTION | METASTASIS | CANCER | MULTIDISCIPLINARY SCIENCES | GENOME | Cells | Deoxyribonucleic acid--DNA
Journal Article
2019, ISBN 3038974730
Mesothelioma is a rare aggressive cancer that develops from the mesothelium. Recent molecular analyses have defined four different types of mesothelioma based... 
tumor microenvironment | mesothelioma | NF2 signaling pathway | experimental mesothelioma models
eBook
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 10, pp. 883 - 892
Journal Article