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The New England Journal of Medicine, ISSN 0028-4793, 12/2017, Volume 377, Issue 25, pp. 2500 - 2501
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2018, Volume 378, Issue 22, pp. 2093 - 2104
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2018, Volume 33, Issue 5, pp. 853 - 861.e4
Journal Article
Medicine, ISSN 0025-7974, 12/2018, Volume 97, Issue 52, p. e13517
Rationale: In the setting of metastatic or locally advanced adrenocortical carcinoma, a limited number of therapies are available and their efficacy is... 
SURVIVAL | high mutational burden | ADJUVANT MITOTANE | metastatic | RESECTION | adrenocortical carcinoma | TUMORS | CANCER | pembrolizumab | MEDICINE, GENERAL & INTERNAL | immunotherapy | ABLATION | BLOCKADE | Usage | Research | High-throughput screening (Biochemical assaying) | Gene mutations
Journal Article
Nature Medicine, ISSN 1078-8956, 2018, Volume 24, Issue 9, pp. 1441 - 1441
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2017, Volume 377, Issue 25, p. 2500
In a survey of the spectrum of mutational burdens in 27 types of cancers, there was a correlation between an increased mutational burden and the response to... 
PD-1 protein | PD-L1 protein | Colorectal cancer | Ligands | Genomes | Mutation | Tumors
Journal Article
The Lancet Oncology, ISSN 1470-2045, 09/2018, Volume 19, Issue 9, pp. e446 - e446
Journal Article
Cancer Science, ISSN 1347-9032, 08/2019, Volume 110, Issue 8, pp. 2620 - 2628
Tumor mutational burden (TMB) and mutational signatures reflect the process of mutation accumulation in cancer. However, the significance of these emerging... 
tumor microenvironment | tumor mutational burden | gene expression | immune checkpoint blockade | mutational signature | NUMBER | COMPREHENSIVE MOLECULAR CHARACTERIZATION | PATTERNS | IDENTIFICATION | TUMORS | REPAIR | ONCOLOGY | GENOMES | HYPERMUTATION | WHOLE EXOME | Genetic aspects | DNA microarrays | Gene expression | Analysis | Cancer | Original
Journal Article