JAMA, ISSN 0098-7484, 05/1997, Volume 277, Issue 18, pp. 1445 - 1451
Objective.—To combine the clinical data from 3 academic institutions that serve as centers of excellence for the surgical treatment of clinically localized...
MEDICINE, GENERAL & INTERNAL | K PY MEDICINE, GENERAL & INTERNAL | METASTASES | MEN | GRADE | RISK | RADICAL PROSTATECTOMY | Multivariate Analysis | Prostatic Neoplasms - pathology | Neoplasm Invasiveness | Humans | Decision Support Techniques | Probability | Male | Lymphatic Metastasis | Prostate-Specific Antigen - analysis | Prostatic Neoplasms - immunology | Neoplasm Staging - methods | Regression Analysis | Sensitivity and Specificity | Prostatectomy | Measurement | Physiological aspects | Prostate-specific antigen | Prostate cancer | Tumor staging | Analysis
MEDICINE, GENERAL & INTERNAL | K PY MEDICINE, GENERAL & INTERNAL | METASTASES | MEN | GRADE | RISK | RADICAL PROSTATECTOMY | Multivariate Analysis | Prostatic Neoplasms - pathology | Neoplasm Invasiveness | Humans | Decision Support Techniques | Probability | Male | Lymphatic Metastasis | Prostate-Specific Antigen - analysis | Prostatic Neoplasms - immunology | Neoplasm Staging - methods | Regression Analysis | Sensitivity and Specificity | Prostatectomy | Measurement | Physiological aspects | Prostate-specific antigen | Prostate cancer | Tumor staging | Analysis
Journal Article
Chest, ISSN 0012-3692, 2007, Volume 132, Issue 3, pp. 234S - 242S
Background: The surgical treatment of stage I and 11 non-small cell lung cancer (NSCLC) continues to evolve in the areas of intraoperative lymph node staging...
Chemotherapy | Stage I and II | Surgery | Non-small cell lung cancer | Ablative therapy | Metaanalyses | Radiotherapy | Adjuvant therapy | Video-assisted thoracic surgery | non-small cell lung cancer | ADJUVANT CHEMOTHERAPY | METAANALYSIS | MAJOR PULMONARY RESECTIONS | metaanalyses | video-assisted thoracic surgery | POSTOPERATIVE RADIOTHERAPY | adjuvant therapy | RANDOMIZED-TRIAL | chemotherapy | SUBLOBAR RESECTION | VINORELBINE PLUS CISPLATIN | RESPIRATORY SYSTEM | ablative therapy | radiotherapy | stage I and II | LOBECTOMY | BRACHYTHERAPY | surgery | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - therapy | Humans | Thoracic Surgery, Video-Assisted | Lung Neoplasms - pathology | Lung Neoplasms - therapy | Sentinel Lymph Node Biopsy | Chemotherapy, Adjuvant | Pneumonectomy | Evidence-Based Medicine | Neoplasm Staging | Radiotherapy, Adjuvant | Care and treatment | Research | Lung cancer, Non-small cell | Tumor staging | Methods | Cancer
Chemotherapy | Stage I and II | Surgery | Non-small cell lung cancer | Ablative therapy | Metaanalyses | Radiotherapy | Adjuvant therapy | Video-assisted thoracic surgery | non-small cell lung cancer | ADJUVANT CHEMOTHERAPY | METAANALYSIS | MAJOR PULMONARY RESECTIONS | metaanalyses | video-assisted thoracic surgery | POSTOPERATIVE RADIOTHERAPY | adjuvant therapy | RANDOMIZED-TRIAL | chemotherapy | SUBLOBAR RESECTION | VINORELBINE PLUS CISPLATIN | RESPIRATORY SYSTEM | ablative therapy | radiotherapy | stage I and II | LOBECTOMY | BRACHYTHERAPY | surgery | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - therapy | Humans | Thoracic Surgery, Video-Assisted | Lung Neoplasms - pathology | Lung Neoplasms - therapy | Sentinel Lymph Node Biopsy | Chemotherapy, Adjuvant | Pneumonectomy | Evidence-Based Medicine | Neoplasm Staging | Radiotherapy, Adjuvant | Care and treatment | Research | Lung cancer, Non-small cell | Tumor staging | Methods | Cancer
Journal Article
Cancer, ISSN 0008-543X, 10/2007, Volume 110, Issue 7, pp. 1532 - 1541
BACKGROUND. Platinum-based adjuvant chemotherapy in randomized trials has failed to provide a survival benefit in patients with resected stage I nonsmall cell...
Histologic grade | Socioeconomic status | Mortality risk | Stage I nonsmall cell lung cancer | Epidemiology | Nonupper lobe tumor locations | Bronchioloalveolar carcinoma | ADJUVANT CHEMOTHERAPY | UNITED-STATES | LOCATION | NUMBER | LYMPH-NODES | RANDOMIZED-TRIAL | POLYMORPHISM | histologic grade | stage I nonsmall cell lung cancer | nonupper lobe tumor locations | epidemiology | CISPLATIN | ONCOLOGY | bronchioloalveolar carcinoma | socioeconomic status | ASSOCIATION | mortality risk | Lung Neoplasms - ethnology | Multivariate Analysis | Predictive Value of Tests | Adenocarcinoma - pathology | Prognosis | Adenocarcinoma, Bronchiolo-Alveolar - pathology | Asian Americans - statistics & numerical data | Lung Neoplasms - mortality | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Adenocarcinoma, Bronchiolo-Alveolar - mortality | Lung Neoplasms - pathology | Male | Carcinoma, Large Cell - mortality | Carcinoma, Squamous Cell - mortality | Adult | Female | Registries | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - surgery | Risk Assessment | California - epidemiology | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Survival Rate | Carcinoma, Non-Small-Cell Lung - mortality | Pneumonectomy - methods | Lung Neoplasms - surgery | Aged | Carcinoma, Non-Small-Cell Lung - enzymology | Neoplasm Staging | Adenocarcinoma - mortality
Histologic grade | Socioeconomic status | Mortality risk | Stage I nonsmall cell lung cancer | Epidemiology | Nonupper lobe tumor locations | Bronchioloalveolar carcinoma | ADJUVANT CHEMOTHERAPY | UNITED-STATES | LOCATION | NUMBER | LYMPH-NODES | RANDOMIZED-TRIAL | POLYMORPHISM | histologic grade | stage I nonsmall cell lung cancer | nonupper lobe tumor locations | epidemiology | CISPLATIN | ONCOLOGY | bronchioloalveolar carcinoma | socioeconomic status | ASSOCIATION | mortality risk | Lung Neoplasms - ethnology | Multivariate Analysis | Predictive Value of Tests | Adenocarcinoma - pathology | Prognosis | Adenocarcinoma, Bronchiolo-Alveolar - pathology | Asian Americans - statistics & numerical data | Lung Neoplasms - mortality | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Adenocarcinoma, Bronchiolo-Alveolar - mortality | Lung Neoplasms - pathology | Male | Carcinoma, Large Cell - mortality | Carcinoma, Squamous Cell - mortality | Adult | Female | Registries | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - surgery | Risk Assessment | California - epidemiology | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Survival Rate | Carcinoma, Non-Small-Cell Lung - mortality | Pneumonectomy - methods | Lung Neoplasms - surgery | Aged | Carcinoma, Non-Small-Cell Lung - enzymology | Neoplasm Staging | Adenocarcinoma - mortality
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 12/2010, Volume 88, Issue 6, pp. 1131 - 1143
Immune responses against Plasmodium parasites, the causative organisms of malaria, are traditionally dichotomized into pre-erythrocytic and blood-stage...
cytokine | adaptive | vaccine | human | innate | falciparum | Human | Innate | Vaccine | Adaptive | Falciparum | Cytokine | NATURAL-KILLER-CELLS | LOW-BIRTH-WEIGHT | HUMAN NK CELLS | DELTA-T-CELLS | IMMUNOLOGY | PLASMODIUM-FALCIPARUM MALARIA | CELL BIOLOGY | ENDOGENOUS IFN-GAMMA | TUMOR-NECROSIS-FACTOR | ANTIGEN-PRESENTING CELLS | NEW-GUINEAN CHILDREN | HEMATOLOGY | PHASE 2A TRIAL | CD4-Positive T-Lymphocytes - immunology | Animals | Humans | Malaria - immunology | Malaria Vaccines - immunology | Interferon-gamma - physiology | CD8-Positive T-Lymphocytes - immunology | Erythrocytes - parasitology | Inflammation - etiology
cytokine | adaptive | vaccine | human | innate | falciparum | Human | Innate | Vaccine | Adaptive | Falciparum | Cytokine | NATURAL-KILLER-CELLS | LOW-BIRTH-WEIGHT | HUMAN NK CELLS | DELTA-T-CELLS | IMMUNOLOGY | PLASMODIUM-FALCIPARUM MALARIA | CELL BIOLOGY | ENDOGENOUS IFN-GAMMA | TUMOR-NECROSIS-FACTOR | ANTIGEN-PRESENTING CELLS | NEW-GUINEAN CHILDREN | HEMATOLOGY | PHASE 2A TRIAL | CD4-Positive T-Lymphocytes - immunology | Animals | Humans | Malaria - immunology | Malaria Vaccines - immunology | Interferon-gamma - physiology | CD8-Positive T-Lymphocytes - immunology | Erythrocytes - parasitology | Inflammation - etiology
Journal Article
PROTEOMICS, ISSN 1615-9853, 11/2019, Volume 19, Issue 21-22, pp. e1800482 - n/a
Epithelial ovarian cancer is one of the most fatal gynecological malignancies in adult women. As studies on protein N‐glycosylation have extensively reported...
mass spectrometry imaging | tissue | N‐glycan | matrix‐assisted laser desorption/ionization | ovarian cancer | formalin‐fixed paraffin‐embedded | Ovarian carcinoma | Spatial discrimination | Paraffin | Tissues | Isomers | Ovarian cancer | Polysaccharides | Paraffins | Spectroscopy | Medical imaging | Markers | Ions | Mass spectroscopy | Liquid chromatography | Glycosylation | Glycan | Spatial distribution | Spatial data | Ionization | Scientific imaging | Diagnostic systems | Mass spectrometry | Tumors | Cancer | Graphitization
mass spectrometry imaging | tissue | N‐glycan | matrix‐assisted laser desorption/ionization | ovarian cancer | formalin‐fixed paraffin‐embedded | Ovarian carcinoma | Spatial discrimination | Paraffin | Tissues | Isomers | Ovarian cancer | Polysaccharides | Paraffins | Spectroscopy | Medical imaging | Markers | Ions | Mass spectroscopy | Liquid chromatography | Glycosylation | Glycan | Spatial distribution | Spatial data | Ionization | Scientific imaging | Diagnostic systems | Mass spectrometry | Tumors | Cancer | Graphitization
Journal Article
Cancer Research, ISSN 0008-5472, 06/2001, Volume 61, Issue 12, pp. 4766 - 4772
Immunosuppression may contribute to the progression of cancer, In this study we assessed the structural and functional status of T tells from tumor specimens...
IMMUNE-SYSTEM | TGF-BETA | CD25 EXPRESSION | ONCOLOGY | PROTEIN EXPRESSION | CERVICAL-CARCINOMA | SIGNALING MOLECULES | COSTIMULATION | COLORECTAL-CARCINOMA | ZETA-CHAIN | LYMPHOCYTES | Humans | Lung Neoplasms - metabolism | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Th1 Cells - immunology | CD3 Complex - biosynthesis | Receptors, Antigen, T-Cell - biosynthesis | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Lymphocyte Activation - immunology | CD8-Positive T-Lymphocytes - metabolism | Transforming Growth Factor beta - secretion | Female | Ovarian Neoplasms - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | CD4 Antigens - immunology | Receptors, Interleukin-2 - biosynthesis | Down-Regulation | CD4-Positive T-Lymphocytes - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Receptors, Interleukin-2 - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | CD4-Positive T-Lymphocytes - secretion | CD4 Antigens - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Interleukin-2 - biosynthesis | Neoplasm Staging | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Ovarian Neoplasms - immunology
IMMUNE-SYSTEM | TGF-BETA | CD25 EXPRESSION | ONCOLOGY | PROTEIN EXPRESSION | CERVICAL-CARCINOMA | SIGNALING MOLECULES | COSTIMULATION | COLORECTAL-CARCINOMA | ZETA-CHAIN | LYMPHOCYTES | Humans | Lung Neoplasms - metabolism | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Th1 Cells - immunology | CD3 Complex - biosynthesis | Receptors, Antigen, T-Cell - biosynthesis | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Lymphocyte Activation - immunology | CD8-Positive T-Lymphocytes - metabolism | Transforming Growth Factor beta - secretion | Female | Ovarian Neoplasms - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | CD4 Antigens - immunology | Receptors, Interleukin-2 - biosynthesis | Down-Regulation | CD4-Positive T-Lymphocytes - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Receptors, Interleukin-2 - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | CD4-Positive T-Lymphocytes - secretion | CD4 Antigens - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Interleukin-2 - biosynthesis | Neoplasm Staging | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Ovarian Neoplasms - immunology
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 5, pp. 1352 - 1358
Purpose To review treatment outcomes for stereotactic body radiotherapy (SBRT) in medically operable patients with Stage I non–small-cell lung cancer (NSCLC),...
Radiology | Hematology, Oncology and Palliative Medicine | Stage I | Stereotactic body radiotherapy | Operable | Lung cancer | Non–small-cell | Non-small-cell | PROGNOSIS | BRONCHOGENIC-CARCINOMA | PHASE-II | Non small-cell | TUMORS | RADIATION-THERAPY | DOSE-ESCALATION | IRRADIATION | ONCOLOGY | LINEAR-ACCELERATOR | EXPERIENCE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CLINICAL-OUTCOMES | Lung Neoplasms - mortality | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Radiosurgery - adverse effects | Aged, 80 and over | Adult | Female | Retrospective Studies | Radiosurgery - methods | Databases, Factual | Carcinoma, Non-Small-Cell Lung - pathology | Radiotherapy Dosage | Carcinoma, Non-Small-Cell Lung - surgery | Japan | Survival Rate | Treatment Outcome | Carcinoma, Non-Small-Cell Lung - mortality | Remission Induction | Disease-Free Survival | Lung Neoplasms - surgery | Aged | Radiosurgery - mortality | Neoplasm Staging | Medical colleges | Oncology, Experimental | Surgery | Research | Lung cancer, Non-small cell | Radiotherapy | Cancer | SURGERY | PATIENTS | NEOPLASMS | LUNGS | GY RANGE 100-1000 | RADIOLOGY AND NUCLEAR MEDICINE | RADIATION DOSES | RADIOTHERAPY | GY RANGE 10-100
Radiology | Hematology, Oncology and Palliative Medicine | Stage I | Stereotactic body radiotherapy | Operable | Lung cancer | Non–small-cell | Non-small-cell | PROGNOSIS | BRONCHOGENIC-CARCINOMA | PHASE-II | Non small-cell | TUMORS | RADIATION-THERAPY | DOSE-ESCALATION | IRRADIATION | ONCOLOGY | LINEAR-ACCELERATOR | EXPERIENCE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CLINICAL-OUTCOMES | Lung Neoplasms - mortality | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Radiosurgery - adverse effects | Aged, 80 and over | Adult | Female | Retrospective Studies | Radiosurgery - methods | Databases, Factual | Carcinoma, Non-Small-Cell Lung - pathology | Radiotherapy Dosage | Carcinoma, Non-Small-Cell Lung - surgery | Japan | Survival Rate | Treatment Outcome | Carcinoma, Non-Small-Cell Lung - mortality | Remission Induction | Disease-Free Survival | Lung Neoplasms - surgery | Aged | Radiosurgery - mortality | Neoplasm Staging | Medical colleges | Oncology, Experimental | Surgery | Research | Lung cancer, Non-small cell | Radiotherapy | Cancer | SURGERY | PATIENTS | NEOPLASMS | LUNGS | GY RANGE 100-1000 | RADIOLOGY AND NUCLEAR MEDICINE | RADIATION DOSES | RADIOTHERAPY | GY RANGE 10-100
Journal Article
Immunity, ISSN 1074-7613, 10/2016, Volume 45, Issue 4, pp. 889 - 902
In recent years, various intervention strategies have reduced malaria morbidity and mortality, but further improvements probably depend upon development of a...
CD8+ T cells | vaccine | memory T cells | liver | tissue-resident memory | liver surveillance | Clec9A | sporozoite | malaria | T cells | CD8 | IMMUNITY | IMMUNIZATION | DENDRITIC CELLS | PROTECTION | STRATEGY | HERPES | RM CELLS | TISSUE | IMMUNOLOGY | ANTIGEN | Liver Diseases - immunology | Plasmodium berghei - immunology | Dendritic Cells - parasitology | Dendritic Cells - immunology | Malaria - immunology | CD8-Positive T-Lymphocytes - parasitology | Liver Diseases - parasitology | Hepatocytes - immunology | Sporozoites - immunology | Hepatocytes - parasitology | Sporozoites - parasitology | Liver - immunology | Animals | Vaccination - methods | Culicidae | Malaria Vaccines - immunology | Mice | Liver - parasitology | CD8-Positive T-Lymphocytes - immunology | Immunologic Memory - immunology | Spleen | Antigens | Flow cytometry | Malaria | Liver | Clinical trials | T cell receptors | Infections | Parasites | Gene expression | Experiments | Lymphocytes | Rodents | Population | Tumor necrosis factor-TNF | Software
CD8+ T cells | vaccine | memory T cells | liver | tissue-resident memory | liver surveillance | Clec9A | sporozoite | malaria | T cells | CD8 | IMMUNITY | IMMUNIZATION | DENDRITIC CELLS | PROTECTION | STRATEGY | HERPES | RM CELLS | TISSUE | IMMUNOLOGY | ANTIGEN | Liver Diseases - immunology | Plasmodium berghei - immunology | Dendritic Cells - parasitology | Dendritic Cells - immunology | Malaria - immunology | CD8-Positive T-Lymphocytes - parasitology | Liver Diseases - parasitology | Hepatocytes - immunology | Sporozoites - immunology | Hepatocytes - parasitology | Sporozoites - parasitology | Liver - immunology | Animals | Vaccination - methods | Culicidae | Malaria Vaccines - immunology | Mice | Liver - parasitology | CD8-Positive T-Lymphocytes - immunology | Immunologic Memory - immunology | Spleen | Antigens | Flow cytometry | Malaria | Liver | Clinical trials | T cell receptors | Infections | Parasites | Gene expression | Experiments | Lymphocytes | Rodents | Population | Tumor necrosis factor-TNF | Software
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 17, pp. 2342 - 2349
Purpose Preoperative aromatase inhibitor (AI) treatment promotes breast-conserving surgery (BCS) for estrogen receptor (ER)-positive breast cancer. To study...
TRIAL | IMPROVED SURGICAL OUTCOMES | MULTICENTER | ONCOLOGY | TAMOXIFEN | ENDOCRINE THERAPY | COMBINATION | EXPRESSION | CHEMOTHERAPY | Prognosis | Biomarkers, Tumor - analysis | Humans | Antineoplastic Agents - therapeutic use | Receptors, Estrogen - analysis | Breast Neoplasms - drug therapy | Breast Neoplasms - chemistry | Ki-67 Antigen - analysis | Breast Neoplasms - pathology | Postmenopause | Female | Neoadjuvant Therapy | Androstadienes - therapeutic use | Neoplasm Staging | Aromatase Inhibitors - therapeutic use | Nitriles - therapeutic use | Triazoles - therapeutic use | Receptors d'hormones | Hormone receptors | Menopausa | Menopause | Estrogen | Càncer de mama | Breast cancer | Assaigs clínics de medicaments | Drug testing | Estrògens | Original Reports | Bc7
TRIAL | IMPROVED SURGICAL OUTCOMES | MULTICENTER | ONCOLOGY | TAMOXIFEN | ENDOCRINE THERAPY | COMBINATION | EXPRESSION | CHEMOTHERAPY | Prognosis | Biomarkers, Tumor - analysis | Humans | Antineoplastic Agents - therapeutic use | Receptors, Estrogen - analysis | Breast Neoplasms - drug therapy | Breast Neoplasms - chemistry | Ki-67 Antigen - analysis | Breast Neoplasms - pathology | Postmenopause | Female | Neoadjuvant Therapy | Androstadienes - therapeutic use | Neoplasm Staging | Aromatase Inhibitors - therapeutic use | Nitriles - therapeutic use | Triazoles - therapeutic use | Receptors d'hormones | Hormone receptors | Menopausa | Menopause | Estrogen | Càncer de mama | Breast cancer | Assaigs clínics de medicaments | Drug testing | Estrògens | Original Reports | Bc7
Journal Article