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Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15, pp. 2963 - 2968
Journal Article
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7539, pp. 422 - 426
Journal Article
The Journal of Nuclear Medicine (1978), ISSN 0161-5505, 2017, Volume 58, Issue 6, pp. 926 - 933
Journal Article
Nature, ISSN 0028-0836, 09/2017, Volume 549, Issue 7670, pp. 96 - 100
Paediatric solid tumours arise from endodermal, ectodermal, or mesodermal lineages(1). Although the overall survival of children with solid tumours is 75%,... 
MULTIPLE-MYELOMA | HETEROGENEITY | BIOBANK | GENOMIC LANDSCAPE | MODELS | MULTIDISCIPLINARY SCIENCES | BORTEZOMIB | INHIBITOR | CANCER | DISCOVERY | PANOBINOSTAT LBH589 | Vincristine - pharmacology | Pyrazoles - therapeutic use | Epigenesis, Genetic | Heterografts - drug effects | Humans | Heterografts - metabolism | Bortezomib - pharmacology | Cell Cycle Proteins - antagonists & inhibitors | Neoplasms - genetics | Female | Indoles - pharmacology | Rhabdomyosarcoma - drug therapy | Clone Cells | Drug Therapy, Combination | Child | Heterografts - pathology | Hydroxamic Acids - pharmacology | Camptothecin - analogs & derivatives | High-Throughput Screening Assays - methods | Pyrazoles - pharmacology | Camptothecin - therapeutic use | Pyrimidines - pharmacology | Xenograft Model Antitumor Assays - methods | Neoplasms - drug therapy | Animals | Bortezomib - therapeutic use | Pyrimidines - therapeutic use | Nuclear Proteins - antagonists & inhibitors | Heterografts - transplantation | Vincristine - therapeutic use | Hydroxamic Acids - therapeutic use | Indoles - therapeutic use | Mice | Rhabdomyosarcoma - genetics | Camptothecin - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Tumors in children | Care and treatment | Diagnosis | Xenotransplantation | Methods | Pediatrics | Rhabdomyosarcoma | Multiple myeloma | Genomes | Neuroblastoma | Gene expression | Vincristine | Patients | Children & youth | Irinotecan | Chemotherapy | Autopsy | Xenografts | Mutation | Children | Cancer | Tumors
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 05/2015, Volume 205, pp. 144 - 154
The existence of drug resistance poses a major obstacle for the treatment of various malignant human cancers. Here, we report on reduction-sensitive reversibly... 
CD44-targeting | Reduction-sensitive | Hyaluronic acid | Drug resistance | Cancer therapy | Crosslinked nanoparticles | CANCER-CELLS | CHEMISTRY, MULTIDISCIPLINARY | POLYMERIC NANOPARTICLES | BIODEGRADABLE MICELLES | LIPOIC ACID | IN-VIVO | PHARMACOLOGY & PHARMACY | BIOMEDICAL APPLICATIONS | MULTIDRUG-RESISTANCE | COPOLYMER MICELLES | BLOCK-COPOLYMER | INTRACELLULAR DRUG | Injections, Intravenous | Breast Neoplasms - immunology | Humans | Drug Resistance, Neoplasm | Doxorubicin - chemistry | Molecular Targeted Therapy | Breast Neoplasms - metabolism | Drug Carriers | Nanoparticles | Tissue Distribution | Antibiotics, Antineoplastic - chemistry | MCF-7 Cells | Hyaluronan Receptors - metabolism | Female | Antibiotics, Antineoplastic - pharmacokinetics | Nanomedicine | Thioctic Acid - chemistry | Doxorubicin - administration & dosage | Lysine - analogs & derivatives | Cross-Linking Reagents - chemistry | Hyaluronic Acid - chemistry | Solubility | Technology, Pharmaceutical - methods | Breast Neoplasms - drug therapy | Chemistry, Pharmaceutical | Doxorubicin - pharmacokinetics | Antibiotics, Antineoplastic - administration & dosage | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Breast Neoplasms - pathology | Mice, Nude | Hyaluronic Acid - analogs & derivatives | Lysine - chemistry | Anthracyclines | Crosslinked polymers | Physiological aspects | Breast cancer | Drug therapy
Journal Article
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 2017, Volume 52, pp. 7 - 15
Abstract Introduction [11 C]Erlotinib PET has shown promise to distinguish non-small cell lung cancer (NSCLC) tumors harboring the activating epidermal growth... 
Radiology | T790M | MET amplification | Acquired resistance | [11C]erlotinib | Epidermal growth factor receptor | Non-small cell lung cancer | C]erlotinib | GEFITINIB | [C-11]erlotinib | T790M MUTATION | CELL LUNG-CANCER | TYROSINE KINASE INHIBITORS | GROWTH-FACTOR RECEPTOR | POSITRON-EMISSION-TOMOGRAPHY | THERAPY | KINETIC-ANALYSIS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ACTIVATING MUTATIONS | C-11-ERLOTINIB | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Positron-Emission Tomography | Receptor, Epidermal Growth Factor - metabolism | Animals | Cell Transformation, Neoplastic | Cell Line, Tumor | Erlotinib Hydrochloride - metabolism | Female | Lung Neoplasms - diagnostic imaging | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Erlotinib | Analysis | Epidermal growth factor | Binding | Biotechnology | Epidermal growth factor receptors | Incubation | Lung cancer | Medical procedures | Positron emission | Non-small cell lung carcinoma | Experiments | Rodents | Coinjection | Cell lines | Xenografts | Tomography | Tumors | Cancer
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2015, Volume 21, Issue 11, pp. 1318 - 1325
Journal Article