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2016, Methods in molecular biology, ISBN 9781493932979, Volume 1388
This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. 
PTEN Phosphohydrolase | Tumor Suppressor Proteins
Web Resource
2012, Springer theses : recognizing outstanding Ph.D. research, ISBN 4431541349
Web Resource
2016, Cold Spring Harbor perspectives in medicine, ISBN 9781621821335, xi, 504 pages
Book
Genes and Development, ISSN 0890-9369, 08/2004, Volume 18, Issue 16, pp. 1909 - 1925
Journal Article
2016, Methods in molecular biology, ISBN 9781493932979, Volume 1388
This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. 
Phosphatases | PTEN Phosphohydrolase | Cellular signal transduction | Tumor Suppressor Proteins
Web Resource
Pathology and Oncology Research, ISSN 1219-4956, 03/2018, pp. 1 - 2
Journal Article
by Creighton, Chad J and Morgan, Margaret and Gunaratne, Preethi H and Wheeler, David A and Gibbs, Richard A and Robertson, Gordon and Chu, Andy and Beroukhim, Rameen and Cibulskis, Kristian and Signoretti, Sabina and Vandin, Fabio and Wu, Hsin-Ta and Raphael, Benjamin J and Verhaak, Roel G.W and Tamboli, Pheroze and Torres-Garcia, Wandaliz and Akbani, Rehan and Weinstein, John N and Reuter, Victor and Hsieh, James J and Brannon, A. Rose and Hakimi, A. Ari and Jacobsen, Anders and Ciriello, Giovanni and Reva, Boris and Ricketts, Christopher J and Linehan, W. Marston and Stuart, Joshua M and Rathmell, W. Kimryn and Hui, Shen and Laird, Peter W and Muzny, Donna and Davis, Caleb and Liu, Xi and Chang, Kyle and Kakkar, Nipun and Treviño, Lisa R and Benton, Susan and Reid, Jeffrey G and Morton, Donna and Doddapaneni, Harsha and Yi, Han and Lewis, Lora and Huyen, Dinh and Kovar, Christie and Zhu, Yiming and Santibanez, Jireh and Min, Wang and Hale, Walker and Kalra, Divya and Getz, Gad and Lawrence, Michael S and Sougnez, Carrie and Carter, Scott L and Sivachenko, Andrey and Lee, Lichtenstein and Stewart, Chip and Voet, Doug and Fisher, Sheila and Gabriel, Stacey B and Lander, Eric and Schumacher, Steve E and Tabak, Barbara and Saksena, Gordon and Onofrio, Robert C and Cherniack, Andrew D and Gentry, Jeff and Ardlie, Kristin and Meyerson, Matthew and Chun, Hye-Jung E and Mungall, Andrew J and Sipahimalani, Payal and Stoll, Dominik and Ally, Adrian and Balasundaram, Miruna and Butterfield, Yaron S.N and Carlsen, Rebecca and Carter, Candace and Chuah, Eric and Coope, Robin J.N and Dhalla, Noreen and Gorski, Sharon and Guin, Ranabir and Hirst, Carrie and Hirst, Martin and Holt, Robert A and Lebovitz, Chandra and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Pleasance, Erin and Plettner, Patrick and Schein, Jacqueline E and Shafiei, Arash and Slobodan, Jared R and Tam, Angela and Thiessen, Nina and Varhol, Richard J and Wye, Natasja and ... and Canc Genome Atlas Res Network and Anal Working Grp
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7456, pp. 43 - 49
Genetic changes underlying clear cell renal cell carcinoma(ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the... 
TRIAL | GENETIC-BASIS | PROTEIN | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | TUMOR-SUPPRESSOR | TARGETS | ARM | KIDNEY CANCER | Proteins | DNA methylation | Mutation | Kinases | Chromosomes | Genes
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 01/2010, Volume 17, Issue 1, pp. 25 - 34
  Protein ubiquitination is a reversible reaction, in which the ubiquitin chains are deconjugated by a family of deubiquitinases (DUBs). The presence of a... 
CYLD | NF-κB | tumor suppressor | deubiquitination | deubiquitinase
Journal Article
Cancer Research, ISSN 0008-5472, 11/2018, Volume 78, Issue 22, pp. 6354 - 6362
The standard treatment for metastatic prostate cancer, androgen deprivation therapy (ADT), is designed to suppress androgen receptor (AR) activity. However,... 
TUMOR-SUPPRESSOR | ANDROGEN-DEPRIVATION | INHIBITION | GENE | ONCOLOGY
Journal Article
FEBS Journal, ISSN 1742-464X, 2019
The prostate apoptosis response-4 (Par-4) tumor suppressor can selectively kill cancer cells via apoptosis while leaving healthy cells unharmed. Full length... 
par-4 | apoptosis | tumor suppressor | disorder | coiled coil
Journal Article
Developmental Dynamics, ISSN 1058-8388, 12/2014, Volume 243, Issue 12, p. NA
Background: The tumor suppressor protein merlin is thought to regulate cell proliferation and cell adhesion through interaction with protein partners. Loss of... 
proliferation | Drosophila | tumor suppressor
Journal Article
Nature, ISSN 0028-0836, 11/2011, Volume 479, Issue 7372, pp. 232 - U112
Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms that drive ageing remain... 
MUTANT MICE | ONCOGENIC RAS | BIOMARKER | MULTIDISCIPLINARY SCIENCES | MOUSE | TUMOR-SUPPRESSOR | PHENOTYPES | BUBR1 INSUFFICIENCY | INHIBITOR | EXPRESSION | FIBROBLASTS
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7336, pp. 104 - 109
The effective use of targeted therapy is highly dependent on the identification of responder patient populations. Loss of FBW7, which encodes a... 
COMPLEX | PROTEIN | CANCERS | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | TUMOR-SUPPRESSOR | DEGRADATION | DIFFERENTIATION | FBW7 UBIQUITIN LIGASE
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 07/2012, Volume 14, Issue 7, pp. 659 - 665
The H19 large intergenic non-coding RNA (lincRNA) is one of the most highly abundant and conserved transcripts in mammalian development, being expressed in... 
NONCODING RNA | INSULIN | MESSENGER-RNA | HUR | NULL MUTATIONS | TUMOR-SUPPRESSOR | MICRORNAS | RNA-BINDING-PROTEIN | EXPRESSION | DELETION | CELL BIOLOGY
Journal Article
Histology and Histopathology, ISSN 0213-3911, 04/2012, Volume 27, Issue 4, pp. 317 - 416
Journal Article
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