X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (863) 863
Publication (165) 165
Book Review (6) 6
Book / eBook (2) 2
Book Chapter (1) 1
Dissertation (1) 1
Government Document (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (683) 683
index medicus (670) 670
cancer (340) 340
mutation (340) 340
female (331) 331
oncology (322) 322
tumor suppressor proteins - genetics (322) 322
ubiquitin thiolesterase - genetics (292) 292
male (280) 280
middle aged (217) 217
tumors (210) 210
tumor-suppressor (203) 203
bap1 (198) 198
genetic aspects (190) 190
aged (180) 180
animals (172) 172
cell biology (164) 164
adult (162) 162
mesothelioma (150) 150
tumor suppressor proteins - metabolism (146) 146
article (144) 144
ubiquitin thiolesterase - metabolism (138) 138
immunohistochemistry (137) 137
expression (134) 134
mutations (134) 134
prognosis (132) 132
research (132) 132
melanoma (131) 131
genetics & heredity (122) 122
carcinoma, renal cell - genetics (119) 119
genes (117) 117
pathology (117) 117
kidney neoplasms - genetics (115) 115
melanoma - genetics (114) 114
proteins (113) 113
biochemistry & molecular biology (112) 112
gene expression (111) 111
tumor suppressor genes (109) 109
uveal melanoma (105) 105
aged, 80 and over (97) 97
analysis (97) 97
gene mutations (96) 96
cell line, tumor (94) 94
gene (94) 94
genetic predisposition to disease (91) 91
mesothelioma - genetics (91) 91
gene expression regulation, neoplastic (89) 89
kidney neoplasms - pathology (89) 89
carcinoma, renal cell - pathology (85) 85
mice (82) 82
metastasis (81) 81
somatic mutations (80) 80
brca1-associated protein-1 (79) 79
multidisciplinary sciences (74) 74
genetics (73) 73
lung neoplasms - genetics (72) 72
biomarkers, tumor - genetics (71) 71
diagnosis (71) 71
breast cancer (70) 70
mesothelioma - pathology (68) 68
health aspects (66) 66
genomics (65) 65
uveal neoplasms - genetics (65) 65
tumor-suppressor gene (64) 64
germ-line mutation (63) 63
predispose (63) 63
survival (63) 63
cell cycle (61) 61
deoxyribonucleic acid--dna (61) 61
cell proliferation (60) 60
development and progression (60) 60
lung neoplasms - pathology (60) 60
malignant mesothelioma (60) 60
apoptosis (59) 59
genomes (59) 59
skin neoplasms - genetics (59) 59
risk factors (58) 58
melanoma - pathology (57) 57
transcription factors - genetics (56) 56
signal transduction (55) 55
ubiquitin (55) 55
dna methylation (53) 53
review (53) 53
care and treatment (52) 52
dna mutational analysis (51) 51
genetic research (51) 51
kidney cancer (51) 51
nuclear proteins - genetics (51) 51
young adult (51) 51
malignant pleural mesothelioma (50) 50
physiological aspects (50) 50
genes, tumor suppressor (49) 49
asbestos (48) 48
carcinoma, renal cell (48) 48
neoplasms (48) 48
neoplasms - genetics (48) 48
research article (47) 47
von hippel-lindau tumor suppressor protein - genetics (47) 47
carcinoma, renal cell - metabolism (46) 46
medical prognosis (46) 46
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (857) 857
French (5) 5
Chinese (2) 2
Dutch (2) 2
German (1) 1
Spanish (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Reviews Cancer, ISSN 1474-175X, 03/2013, Volume 13, Issue 3, pp. 153 - 159
BAP1 is a deubiquitylase that is found associated with multiprotein complexes that regulate key cellular pathways, including the cell cycle, cellular... 
COMPLEX | MELANOMA | GENE | ONCOLOGY | SHORT ARM | MUTATION | TUMOR-SUPPRESSOR | UVEAL | UBIQUITIN HYDROLASE | BRCA1-ASSOCIATED PROTEIN-1 | MESOTHELIOMA EPIDEMIC | Ubiquitin | Gene mutations | Physiological aspects | Mesothelioma | Genetic aspects | Research | Health aspects
Journal Article
Journal Article
Pathology, ISSN 0031-3025, 02/2013, Volume 45, Issue 2, pp. 116 - 126
BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its... 
pathology | familial cancer | uveal melanoma | skin | diagnosis | inherited tumour susceptibility | melanoma | 3p21 loss syndrome | atypical Spitz tumour | germline mutation | BAP1 | Pathology | Inherited tumour susceptibility | Melanoma | Uveal melanoma | Atypical Spitz tumour | Familial cancer | Germline mutation | Skin | Diagnosis | PLEURAL MESOTHELIOMA | DNA-DAMAGE RESPONSE | BRCA1-ASSOCIATED PROTEIN-1 | RENAL-CELL CARCINOMA | BREAST-CANCER | POLYCOMB GROUP PROTEINS | SPITZ NEVI | HISTONE DEACETYLASE INHIBITORS | MALIGNANT MESOTHELIOMA | MYELODYSPLASTIC SYNDROMES | Neoplasms - metabolism | Carcinoma, Neuroendocrine - diagnosis | Melanoma - diagnosis | Humans | Lung Neoplasms - metabolism | Meningioma - genetics | Neoplasms - diagnosis | Paraganglioma - diagnosis | Adenocarcinoma - metabolism | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Gene Deletion | Nevus, Epithelioid and Spindle Cell - genetics | Skin Neoplasms - diagnosis | Tumor Suppressor Proteins - genetics | Biomarkers, Tumor - metabolism | Adenocarcinoma - genetics | Uveal Neoplasms - metabolism | Carcinoma, Neuroendocrine - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Uveal Neoplasms - genetics | Genetic Predisposition to Disease | Meningioma - metabolism | Paraganglioma - genetics | Carcinoma, Neuroendocrine - genetics | Mesothelioma - diagnosis | Mesothelioma - genetics | Nevus, Epithelioid and Spindle Cell - metabolism | Ubiquitin Thiolesterase - genetics | Skin Neoplasms - metabolism | Immunohistochemistry - methods | Nevus, Epithelioid and Spindle Cell - diagnosis | Adenocarcinoma - diagnosis | Mesothelioma - metabolism | Paraganglioma - metabolism | Skin Neoplasms - genetics | Uveal Neoplasms - diagnosis | Biomarkers, Tumor - genetics | Meningioma - diagnosis | Mutation | Lung Neoplasms - diagnosis
Journal Article
Human Pathology, ISSN 0046-8177, 2016, Volume 60, pp. 82 - 85
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2012, Volume 44, Issue 7, pp. 751 - 759
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2015, Volume 21, Issue 11, pp. 1344 - 1349
Journal Article
Journal Article
NATURE, ISSN 0028-0836, 06/2017, Volume 546, Issue 7659, pp. 549 - 549
BRCA1-associated protein 1 (BAP1) is a potent tumour suppressor gene that modulates environmental carcinogenesis(1-3). All carriers of inherited heterozygous... 
HUMAN MESOTHELIAL CELLS | APOPTOSIS | PREDISPOSES | STRAND BREAK REPAIR | MULTIDISCIPLINARY SCIENCES | GERMLINE MUTATIONS | TUMOR-SUPPRESSOR | ENDOPLASMIC-RETICULUM | MALIGNANT MESOTHELIOMA | CANCER | ASBESTOS | Physiological aspects | Cell interaction | Tumor suppressor genes | Observations | Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2012, Volume 337, Issue 6101, pp. 1541 - 1546
De-ubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with increased risk of mesothelioma and uveal melanoma. Somatic BAP1 mutations occur... 
Spleen | Myeloid cells | Genes | DNA | REPORTS | Stem cells | Neutrophils | Bone marrow | Bone marrow cells | Genetic mutation | Tumors | ASXL1 | MULTIDISCIPLINARY SCIENCES | MOUSE | GENE-EXPRESSION | MUTATIONS | LEUKEMIA | UBIQUITIN HYDROLASE | PREDISPOSE | MYELODYSPLASTIC SYNDROMES | Myeloid Cells - cytology | Humans | Leukemia, Myelomonocytic, Chronic - genetics | Myeloid Cells - physiology | Host Cell Factor C1 - metabolism | Leukemia, Myelomonocytic, Chronic - metabolism | Chromatin Immunoprecipitation | Hematopoiesis | Gene Deletion | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Bone Marrow Transplantation | Myeloid Progenitor Cells - cytology | Ubiquitin Thiolesterase - metabolism | Leukemia, Myelomonocytic, Chronic - pathology | Genes, Tumor Suppressor | Repressor Proteins - metabolism | Promoter Regions, Genetic | Myelodysplastic Syndromes - metabolism | Tumor Suppressor Proteins - metabolism | Gene Expression Regulation | Embryonic Development | Ubiquitin Thiolesterase - genetics | N-Acetylglucosaminyltransferases - metabolism | Gene Knock-In Techniques | Mice, Knockout | Animals | Myeloid Progenitor Cells - physiology | Cell Transformation, Neoplastic | Mice | Myelodysplastic Syndromes - genetics | Myelodysplastic Syndromes - pathology | Ubiquitin Thiolesterase - chemistry | Gene silencing | Tumor suppressor genes | Genetic engineering | Research | Properties | Observations | Enzymes | Mutation | Gene expression | Molecular biology | Leukemia
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 04/2015, Volume 10, Issue 4, pp. 565 - 576
Journal Article