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Journal Article
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 03/2017, Volume 56, Issue 3, pp. 886 - 894
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2010, Volume 11, Issue 2, pp. 141 - 147
Journal Article
European Journal of Surgical Oncology, ISSN 0748-7983, 2011, Volume 37, Issue 7, pp. 597 - 603
Abstract Introduction MiRNAs regulate gene expression by binding to target sites and initiating translational repression and/or mRNA degradation. Studies have... 
Hematology, Oncology and Palliative Medicine | Surgery | miRNA-21 | Colorectal cancer | PDCD4 tumour suppressor | TRANSFORMATION | SURGERY | PROTEIN | METASTASIS | TUMOR-SUPPRESSOR PDCD4 | ENDOGENOUS CONTROL GENES | DOWN-REGULATION | HUMAN BREAST-CANCER | BETA-CATENIN/TCF | COLON-CARCINOMA CELLS | ONCOLOGY | MIR-21 | Immunohistochemistry | RNA-Binding Proteins - genetics | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Adenoma - surgery | Adenoma - genetics | Humans | Middle Aged | Male | MicroRNAs - metabolism | Colonic Polyps - metabolism | Colonic Neoplasms - metabolism | Adenoma - metabolism | Neoplasm Recurrence, Local - pathology | Colonic Neoplasms - surgery | Adenocarcinoma - metabolism | Colonic Polyps - genetics | Rectal Neoplasms - genetics | Aged, 80 and over | Apoptosis Regulatory Proteins - genetics | Female | Adenocarcinoma - genetics | Rectal Neoplasms - pathology | Gene Expression | Neoplasm Recurrence, Local - metabolism | Rectal Neoplasms - surgery | Colon - metabolism | Apoptosis Regulatory Proteins - metabolism | Analysis of Variance | Colonic Neoplasms - pathology | Adenoma - pathology | Neoplasm Recurrence, Local - genetics | Aged | MicroRNAs - genetics | Rectal Neoplasms - metabolism | Neoplasm Staging | RNA-Binding Proteins - metabolism | Adenocarcinoma - surgery | Gene expression | Messenger RNA
Journal Article
Science Signaling, ISSN 1945-0877, 11/2011, Volume 4, Issue 199, pp. ra75 - ra75
The mechanisms linking immune responses and inflammation with tumor development are not well understood. Here, we show that the soluble form of the... 
BREAST-CANCER | GROWTH-FACTOR-BETA | TGF-BETA | PROTEIN | MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR PDCD4 | TOLL-LIKE RECEPTORS | CELL-DEATH 4 | EXPRESSION | PROGRAMMED CELL-DEATH-4 | CELL BIOLOGY | Inflammation - pathology | Toll-Like Receptor 2 - genetics | Humans | Transforming Growth Factor beta1 - metabolism | MicroRNAs - metabolism | Inflammation - metabolism | Sepsis - metabolism | Toll-Like Receptor 4 - agonists | Decorin - genetics | Apoptosis Regulatory Proteins - immunology | Signal Transduction | RNA-Binding Proteins - immunology | Macrophages, Peritoneal - immunology | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | MicroRNAs - immunology | Toll-Like Receptor 4 - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Mice, Nude | Neoplasms - immunology | Interleukin-10 - genetics | Cell Line, Tumor | Toll-Like Receptor 2 - immunology | Mice | MicroRNAs - genetics | Macrophages, Peritoneal - metabolism | Interleukin-10 - immunology | RNA-Binding Proteins - metabolism | Neoplasms - metabolism | Neoplasm Transplantation | RNA-Binding Proteins - genetics | Toll-Like Receptor 2 - agonists | Macrophages, Peritoneal - pathology | Transplantation, Heterologous | Transforming Growth Factor beta1 - immunology | Decorin - immunology | Sepsis - pathology | Neoplasms - genetics | Apoptosis Regulatory Proteins - genetics | Interleukin-10 - metabolism | Sepsis - immunology | Inflammation - immunology | Transforming Growth Factor beta1 - genetics | Mice, Inbred C3H | Sepsis - genetics | Animals | Inflammation - genetics | Neoplasms - pathology | Decorin - metabolism | Life Sciences | Cellular Biology
Journal Article
Human Pathology, ISSN 0046-8177, 2014, Volume 46, Issue 1, pp. 50 - 57
Summary Programmed cell death 4 (PDCD4) is a tumor suppressor gene involved in tumorogenesis. MicroRNA-21 (miR-21) specifically targets PDCD4, and recent... 
Pathology | Immunohistochemistry | PDCD4 | Akt | MiR-21 | Medullary thyroid cancer | RET | CHEMOSENSITIVITY | PROTEIN | TUMOR-SUPPRESSOR PDCD4 | DOWN-REGULATION | CELL-DEATH 4 | PATHOLOGY | CANCER | OVEREXPRESSION | EXPRESSION | Up-Regulation | ras Proteins - genetics | Phosphorylation | Humans | Middle Aged | Apoptosis Regulatory Proteins - analysis | Gene Expression Regulation, Neoplastic | Thyroid Neoplasms - blood | Child, Preschool | Thyroid Neoplasms - chemistry | Male | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Adult | Female | Retrospective Studies | Child | Real-Time Polymerase Chain Reaction | RNA-Binding Proteins - analysis | Calcitonin - blood | Genetic Predisposition to Disease | Thyroid Neoplasms - mortality | Signal Transduction | Biomarkers, Tumor - analysis | Down-Regulation | Biomarkers, Tumor - blood | Thyroid Neoplasms - genetics | Phenotype | Ki-67 Antigen - analysis | Carcinoma, Neuroendocrine | Biopsy | Proto-Oncogene Proteins c-akt - analysis | Aged | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Mutation | Neoplasm Staging | Proto-Oncogene Proteins c-ret - genetics | Thyroid Neoplasms - pathology | Carcinoma | Sarcoma | Analysis | Thyroid diseases | Cancer | Thyroid cancer | Cell death | Proteins | Studies | Polymerase chain reaction | Genes | Medical prognosis | MicroRNAs | Kinases
Journal Article