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Immunity, ISSN 1074-7613, 2006, Volume 25, Issue 5, pp. 695 - 697
Journal Article
Immunity, ISSN 1074-7613, 2006, Volume 25, Issue 5, pp. 745 - 755
Journal Article
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7414, pp. 155 - 159
The identification of somatic activating mutations in JAK2 (refs 1-4) and in the thrombopoietin receptor gene (MPL)(5) in most patients with myeloproliferative... 
MYELOFIBROSIS | LUNG-CANCER | POLYCYTHEMIA-VERA | GEFITINIB | MYELOPROLIFERATIVE DISORDERS | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | BCR-ABL | MUTATION | RESISTANCE | CHRONIC MYELOID-LEUKEMIA | Myeloproliferative Disorders - enzymology | Phosphorylation | Protein Biosynthesis | Humans | Protein Multimerization | STAT Transcription Factors - metabolism | TYK2 Kinase - metabolism | Janus Kinase 1 - deficiency | TYK2 Kinase - deficiency | Myeloproliferative Disorders - pathology | Janus Kinase 1 - biosynthesis | Gene Knockdown Techniques | Janus Kinase 2 - deficiency | Janus Kinase 1 - metabolism | Granulocytes - drug effects | RNA Interference | Janus Kinase 1 - genetics | Janus Kinase 2 - metabolism | Myeloproliferative Disorders - metabolism | Granulocytes - metabolism | Janus Kinase 2 - antagonists & inhibitors | Disease Models, Animal | Cell Line | Janus Kinase 2 - genetics | Myeloproliferative Disorders - drug therapy | Enzyme Activation - drug effects | TYK2 Kinase - biosynthesis | Granulocytes - enzymology | Animals | Signal Transduction - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | HSP90 Heat-Shock Proteins - metabolism | Mice | TYK2 Kinase - genetics | Drug Resistance, Neoplasm - drug effects | Enzyme inhibitors | Gene mutations | Cancer cells | Dosage and administration | Genetic aspects | Cellular signal transduction | Identification and classification | Physiological aspects | Care and treatment | Research | Myeloproliferative disorders | Cancer | tyrosine kinase inhibitors | persistence | MPN | JAK2 | resistance
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 10, pp. 1641 - 1662
Journal Article
European Journal of Immunology, ISSN 0014-2980, 11/2016, Volume 46, Issue 11, pp. 2639 - 2649
Journal Article
Current Opinion in Allergy and Clinical Immunology, ISSN 1528-4050, 12/2007, Volume 7, Issue 6, pp. 506 - 509
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2015, Volume 195, Issue 10, pp. 5011 - 5024
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2013, Volume 191, Issue 4, pp. 1845 - 1855
Iron is a trace element important for the proper folding and function of various proteins. Physiological regulation of iron stores is of critical importance... 
IL-TIF | INDUCIBLE FACTOR | INFLAMMATION | MOUSE MODEL | INTERLEUKIN-22 | CYTOKINE | MICE | PROINFLAMMATORY GENE-EXPRESSION | T-CELL | IMMUNOLOGY | IL-10 | Liver - pathology | Phosphorylation | Recombinant Fusion Proteins - pharmacology | Humans | Receptors, IgG - deficiency | TYK2 Kinase - metabolism | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | TYK2 Kinase - deficiency | Hepatocytes - metabolism | Anemia, Iron-Deficiency - blood | Interleukins - genetics | RNA, Messenger - biosynthesis | Interleukins - physiology | Hepcidins - physiology | Hepcidins - immunology | Interleukin-6 - physiology | Iron - deficiency | Female | Interleukins - pharmacology | Spleen - pathology | Hepcidins - antagonists & inhibitors | Job Syndrome - metabolism | Antibodies, Monoclonal - immunology | STAT3 Transcription Factor - metabolism | Iron - blood | Amino Acid Sequence | Receptors, Interleukin - physiology | Signal Transduction | Hepcidins - biosynthesis | Receptors, Interleukin - agonists | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Mice, SCID | Iron - metabolism | Interleukins - toxicity | Anemia, Iron-Deficiency - chemically induced | Mice, Knockout | Animals | Immunoglobulin G - genetics | Spleen - metabolism | Hepcidins - genetics | Protein Processing, Post-Translational | Immunoglobulin Fc Fragments - genetics
Journal Article
PLoS One, ISSN 1932-6203, 2017, Volume 12, Issue 10, p. e0186317
Interleukin-10 (IL-10) is an anti-inflammatory cytokine that plays a key role in maintainingimmune homeostasis. IL-10-mediated responses are triggered upon... 
INTERLEUKIN-10 RECEPTOR COMPLEX | SOCS3 | HUMAN NEUTROPHILS | PATHWAY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | MECHANISMS | MODEL | EXPRESSION | BINDING | T-CELLS | Dendritic Cells - immunology | Tumor Necrosis Factor-alpha - genetics | TYK2 Kinase - deficiency | TYK2 Kinase - immunology | Signal Transduction - immunology | Bone Marrow Cells - immunology | Cloning, Molecular | Tumor Necrosis Factor-alpha - immunology | Bone Marrow Cells - drug effects | Dendritic Cells - drug effects | Protein Interaction Domains and Motifs | Protein Isoforms - deficiency | Suppressor of Cytokine Signaling 3 Protein - immunology | Macrophages - immunology | STAT3 Transcription Factor - genetics | Receptors, Interleukin-10 - immunology | Recombinant Proteins - metabolism | Mast Cells - immunology | Gene Expression | Bone Marrow Cells - cytology | Tobacco - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Suppressor of Cytokine Signaling 3 Protein - genetics | Macrophages - cytology | Organ Specificity | Mast Cells - drug effects | Mice, Knockout | Animals | Tobacco - genetics | Interleukin-10 - genetics | Lipopolysaccharides - pharmacology | Mast Cells - cytology | Protein Binding | Macrophages - drug effects | Dendritic Cells - cytology | Mice | Primary Cell Culture | Receptors, Interleukin-10 - deficiency | STAT3 Transcription Factor - immunology | TYK2 Kinase - genetics | Protein Isoforms - immunology | Interleukin-10 - immunology | Interleukin-10 - pharmacology | Protein Isoforms - genetics | Receptors, Interleukin-10 - genetics | Homeostasis | Research | Interleukin-10 | Dendritic cells | Tyk2 protein | Laboratories | Interleukin | Intracellular signalling | Activation | Kinases | Macrophages | Experiments | Lipopolysaccharides | Bone marrow | Janus kinase | Plant sciences | Antigens | Cytokines | Neutrophils | Stat3 protein | Inflammation | Tumor necrosis factor-α | Biological activity | Studies | Molecular modelling | Interleukin 10 | Mast cells | Bone | Intracellular | Laboratorium voor Nematologie | Laboratory of Nematology | EPS | PE&RC
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2012, Volume 16, Issue 6, pp. 814 - 824
Journal Article