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Cancers, ISSN 2072-6694, 12/2016, Volume 8, Issue 12, p. 107
The TAM family of receptors (i.e., Tyro3, Axl, and Mertk), and their ligands Growth arrest specific factor 6 (Gas6) and Protein S (Pros1) contribute to several... 
Axl | Tumor microenvironment | Protein S | Tyro3 | Immune evasion | Gas6 | Mertk | TYROSINE KINASE | ARREST-SPECIFIC GENE-6 | protein S | SMALL-MOLECULE INHIBITOR | BREAST-CANCER | immune evasion | ONCOLOGY | GROWTH-ARREST | APOPTOTIC CELLS | IN-VIVO | tumor microenvironment | PROTEIN-S | TYRO-3 FAMILY | UP-REGULATION | Proteins | Ligands | Cellular biology | Tumors
Journal Article
Journal of Neuroimmune Pharmacology, ISSN 1557-1890, 6/2008, Volume 3, Issue 2, pp. 130 - 140
Removal of apoptotic cells is an essential process for normal development and tissue maintenance. Importantly, apoptotic cells stimulate their phagocytosis by... 
Neurosciences | Biomedicine | Immunology | Rac | iNOS | Vav | Pharmacology/Toxicology | IL-1β | microglia | Phagocytosis | Cell Biology | Virology | INOS | Microglia | NITRIC-OXIDE SYNTHASE | PHOSPHATIDYLSERINE RECOGNITION | IL-1 beta | NEUROSCIENCES | RECEPTOR-MEDIATED PHAGOCYTOSIS | CYTOKINE PRODUCTION | CORTICAL-NEURONS | APOPTOTIC CELLS | GROWTH-ARREST | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | TYRO-3 FAMILY | ARREST-SPECIFIC GENE | Transcription, Genetic - drug effects | Nitric Oxide Synthase Type II - biosynthesis | Phosphorylation | Apoptosis - drug effects | Receptor Protein-Tyrosine Kinases - physiology | rac GTP-Binding Proteins - metabolism | Cell Line - enzymology | Interleukin-1beta - genetics | Oncogene Proteins - physiology | Brain - metabolism | Cell Line - drug effects | Cell Line - physiology | Microglia - physiology | Nitric Oxide Synthase Type II - antagonists & inhibitors | c-Mer Tyrosine Kinase | Interleukin-1beta - biosynthesis | Interleukin-1beta - antagonists & inhibitors | Recombinant Fusion Proteins - biosynthesis | Phagocytosis - drug effects | Lipopolysaccharides - toxicity | Microglia - drug effects | Phagocytosis - physiology | Microglia - enzymology | Cytoskeleton - ultrastructure | Gene Expression Regulation - drug effects | Animals | Nitric Oxide Synthase Type II - genetics | Intercellular Signaling Peptides and Proteins - pharmacology | Proto-Oncogene Proteins - physiology | Inflammation - genetics | Cytoskeleton - physiology | Mice | Protein Processing, Post-Translational | Apoptosis - physiology | Proto-Oncogene Proteins c-vav - metabolism | Phenols | Gene expression | Phosphotransferases | Kinases | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 532, Issue 7598, pp. 240 - 244
Journal Article
BLOOD, ISSN 0006-4971, 01/2007, Volume 109, Issue 2, pp. 653 - 660
Dendritic cells (DCs) play a key role in immune homeostasis and maintenance of self-tolerance. Tolerogenic DCs can be established by an encounter with... 
SIGNALING PATHWAYS | IMMUNE-RESPONSES | LIVER DEGENERATION | IN-VIVO | RECEPTOR | MATURATION | HEMATOLOGY | IMMUNOSTIMULATORY FUNCTION | TYRO-3 FAMILY | MICE LACKING | INNATE IMMUNITY
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2018, Volume 201, Issue 9, pp. 2602 - 2611
Resolution of the inflammatory response requires coordinated regulation of pro- and anti-inflammatory mediator production, together with clearance of recruited... 
IN-VITRO | PHAGOCYTOSIS | APOPTOTIC CELL CLEARANCE | FC-GAMMA-RIII | HUMAN MACROPHAGES | INFLAMMATION | ANNEXIN-V | TAM RECEPTORS | IMMUNOLOGY | TYRO-3 FAMILY | BINDING
Journal Article
Neuron, ISSN 0896-6273, 09/2013, Volume 79, Issue 5, pp. 873 - 886
Journal Article
Nature immunology, ISSN 1529-2908, 10/2014, Volume 15, Issue 10, pp. 920 - 928
The clearance of apoptotic cells is critical for both tissue homeostasis and the resolution of inflammation. We found that the TAM receptor tyrosine kinases... 
BREAST-CANCER | IMMUNE-RESPONSE | CLEARANCE | DENDRITIC CELLS | PLASMA-CONCENTRATIONS | SOLUBLE FORM | AXL | APOPTOTIC CELLS | IN-VIVO | IMMUNOLOGY | TYRO-3 FAMILY | Gene Expression - drug effects | Dendritic Cells - immunology | Receptor Protein-Tyrosine Kinases - immunology | Immunoblotting | Lipopolysaccharides - immunology | Intercellular Signaling Peptides and Proteins - metabolism | Bone Marrow Cells - immunology | c-Mer Tyrosine Kinase | Gene Expression - immunology | Proto-Oncogene Proteins - immunology | Dendritic Cells - metabolism | Macrophages - immunology | Proto-Oncogene Proteins - metabolism | Microscopy, Electron, Scanning | Mice, Inbred C57BL | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Phagocytosis - immunology | Proto-Oncogene Proteins - genetics | Protein Binding - immunology | Receptor Protein-Tyrosine Kinases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microscopy, Confocal | Macrophages - metabolism | Animals | Apoptosis - immunology | Receptor Protein-Tyrosine Kinases - genetics | Dendritic Cells - ultrastructure | Lipopolysaccharides - pharmacology | Bone Marrow Cells - metabolism | Intercellular Signaling Peptides and Proteins - immunology | Cell receptors | Regulation | Genetic aspects | Immune response | Properties | Phosphotransferases
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 02/2005, Volume 115, Issue 2, pp. 237 - 246
Mechanisms regulatine thrombus stabilization remain largely unknown. Here, we report that loss of any 1 of the Gas6 receptors (Gas6-Rs), i.e., Tyro3, Axl, or... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | BETA-3-INTEGRIN-DEFICIENT MICE | AXL | GROWTH | KINASE RECEPTOR | INTEGRIN TYROSINE PHOSPHORYLATION | LIGAND | PHOSPHOINOSITIDE 3-KINASE | TYRO-3 FAMILY | AGGREGATION
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 10/2010, Volume 1209, Issue 1, pp. 23 - 29
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 2010, Volume 22, Issue 6, pp. 740 - 746
Journal Article