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Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2019, Volume 55, Issue 80, pp. 12040 - 12043
A visible light-induced self-powered sensor for the detection of tyrosinase activity was proposed. A tyrosinase-responsive photoelectrochemical-chemical redox... 
Organic chemistry | Cycles | Tyrosinase
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2019, Volume 34, Issue 1, pp. 279 - 309
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning.... 
inhibitor | depigmentation agents | antibrowning compounds | Tyrosinase | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | KOJIC ACID-DERIVATIVES | MOLECULAR DOCKING | POTENT ANTI-TYROSINASE | IN-VITRO | AGARICUS-BISPORUS TYROSINASE | DITHIOCARBAMATE SODIUM-SALTS | MUSHROOM TYROSINASE | BIOLOGICAL EVALUATION | DOPA OXIDASE ACTIVITY | P-COUMARIC ACID
Journal Article
by Kim, YJ and Uyama, H
CELLULAR AND MOLECULAR LIFE SCIENCES, ISSN 1420-682X, 08/2005, Volume 62, Issue 15, pp. 1707 - 1723
Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining the color of mammalian skin and hair. Various dermatological disorders,... 
SLOW-BINDING INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | melanogenesis | food browning | KOJIC ACID | tyrosinase | MAMMALIAN MELANOGENESIS | CELL BIOLOGY | hyperpigmentation | MELANIN BIOSYNTHESIS PATHWAY | inhibitor | AGARICUS-BISPORUS TYROSINASE | MUSHROOM TYROSINASE | POLYPHENOL OXIDASE | COPPER ACTIVE-SITE | DOPAMINE BETA-MONOOXYGENASE | NEUROSPORA-CRASSA
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 01/2012, Volume 20, Issue 2, pp. 1090 - 1099
Resveratrol exhibited the inhibitory activity against mushroom tyrosinase (EC1.14.18.1) through a k inhibition. Resveratrol itself did not inhibit tyrosinase... 
Resveratrol | Inhibitor | Melanogenesis | Tyrosinase
Journal Article
Polymer Chemistry, ISSN 1759-9954, 02/2019, Volume 10, Issue 7, pp. 823 - 826
By inserting short peptide motifs derived from Mfp-3 and Mfp-5 into elastin-like polypeptides (ELPs), we created several recombinant protein polymers that can... 
POLYMER SCIENCE | TYROSINASE | HYDROGEL
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 1, pp. 73 - 79
Abnormal pigmentation owing to excessive melanin synthesis can result in serious problems such as freckles, age-spots, and melanoma. Tyrosinase inhibitors have... 
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 11/2016, Volume 16, Issue 27, pp. 3033 - 3047
Among the human copper-containing monooxygenases, Tyrosinase (Ty) is an important enzyme involved in the determinant step of the biosynthetic pathway of... 
TRP-1 | Tyrosinase effectors | TRP-2 | Tyrosinase | Melanoma | HIGH-RISK MELANOMA | CHEMISTRY, MEDICINAL | ACTIVE-SITE | CRYSTAL-STRUCTURE | CATECHOL OXIDASE | KOJIC ACID | MALIGNANT-MELANOMA | METASTATIC MELANOMA | INHIBITION-MECHANISM | MUSHROOM TYROSINASE | STREPTOMYCES-ANTIBIOTICUS TYROSINASE
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 4, pp. 535 - 539
Pigmentation reflects skin darkening caused by melanin production, but excessive melanin synthesis may cause problems, such as melasma, solar lentigo, dark... 
Journal Article
Angewandte Chemie, ISSN 0044-8249, 11/2017, Volume 129, Issue 46, p. 14544
Zink statt Kupfer: l-Tyrosin wird in einer Sequenz von Reaktionen in das schutzende Polymer Melanin umgewandelt. Im Menschen startet der Stoffwechselweg mit... 
Tyrosinase | Melanin
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2014, Volume 14, Issue 12, pp. 1486 - 1493
Tyrosinase (EC 1.14.18.1), also known as polyphenols oxidase, is a glycosylated multi-copper monooxygenase enzyme widely distributed in many different... 
Tyrosinase inhibitors | Browning | Flavonoids | Skin pigmentation | Melanin | Tyrosinase | MELANIN SYNTHESIS | CHEMISTRY, MEDICINAL | MECHANISM | melanin | skin pigmentation | browning | COMPONENTS | POLYPHENOLS | MUSHROOM TYROSINASE | ANTIOXIDANT | CHALCONES | ROOTS | STILBENES | flavonoids | tyrosinase inhibitors | CONSTITUENTS
Journal Article
PROCESS BIOCHEMISTRY, ISSN 1359-5113, 11/2019, Volume 86, pp. 205 - 214
Clausena lansium (Lour.) Skeels is a fruit tree as well as medicinal plant. Its bark was selected as a raw material for extracting condensed tannins. In this... 
PROANTHOCYANIDINS | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTHOCYANINS | TYROSINASE INHIBITORS | ENGINEERING, CHEMICAL | IN-VITRO | MUSHROOM TYROSINASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GRAPE SEED | KINETICS | Clausena lansium | alpha-Glucosidase | Condensed tannins | Tyrosinase | INTERACTION MECHANISM | Apoptosis | INSIGHTS
Journal Article
Molecular Biotechnology, ISSN 1073-6085, 1/2015, Volume 57, Issue 1, pp. 45 - 57
Journal Article
Comprehensive Reviews in Food Science and Food Safety, ISSN 1541-4337, 07/2012, Volume 11, Issue 4, pp. 378 - 398
:  Tyrosinase (EC 1.14.18.1), a copper‐containing enzyme, can cause enzymatic browning in raw fruits, vegetables, and beverages. Browning is an undesirable... 
FAR-INFRARED IRRADIATION | MUSHROOM TYROSINASE | POLYPHENOL OXIDASE | ANTIOXIDANT ACTIVITIES | ANTI-TYROSINASE | FOOD SCIENCE & TECHNOLOGY | BIOLOGICAL EVALUATION | ASCORBIC-ACID | ETHANOL EXTRACTS | DERIVATIVES | BY-PRODUCT
Journal Article
Research on Chemical Intermediates, ISSN 0922-6168, 5/2018, Volume 44, Issue 5, pp. 2999 - 3015
In the present study, eight new substituted bis-hydroxychalcones for the first time were designed, synthesized, purified and fully characterized. Then their... 
Chemistry | Synthesis | Bis-hydroxychalcones | Physical Chemistry | Molecular modeling | Inhibitor | Drug design | Catalysis | Inorganic Chemistry | Tyrosinase enzyme | IN-SILICO | CRYSTAL-STRUCTURE | ANTIBACTERIAL | TYROSINASE INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | MUSHROOM TYROSINASE | OXIDASES | CHALCONES | DERIVATIVES | Antioxidants | Enzymes | Analysis
Journal Article