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Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2006, Volume 130, Issue 7, pp. 2031 - 2038
Journal Article
Nature (London), ISSN 1476-4687, 07/2012, Volume 489, Issue 7414, pp. 155 - 159
...) in most patients with myeloproliferative neoplasm (MPN) led to the clinical development of JAK2 kinase inhibitors(6,7... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Myeloproliferative Disorders - enzymology | Phosphorylation | Protein Biosynthesis | Humans | Protein Multimerization | STAT Transcription Factors - metabolism | TYK2 Kinase - metabolism | Janus Kinase 1 - deficiency | TYK2 Kinase - deficiency | Myeloproliferative Disorders - pathology | Janus Kinase 1 - biosynthesis | Gene Knockdown Techniques | Janus Kinase 2 - deficiency | Janus Kinase 1 - metabolism | Granulocytes - drug effects | RNA Interference | Janus Kinase 1 - genetics | Janus Kinase 2 - metabolism | Myeloproliferative Disorders - metabolism | Granulocytes - metabolism | Janus Kinase 2 - antagonists & inhibitors | Disease Models, Animal | Cell Line | Janus Kinase 2 - genetics | Myeloproliferative Disorders - drug therapy | Enzyme Activation - drug effects | TYK2 Kinase - biosynthesis | Granulocytes - enzymology | Animals | Signal Transduction - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | HSP90 Heat-Shock Proteins - metabolism | Mice | TYK2 Kinase - genetics | Drug Resistance, Neoplasm - drug effects | Enzyme inhibitors | Gene mutations | Cancer cells | Dosage and administration | Genetic aspects | Cellular signal transduction | Identification and classification | Physiological aspects | Care and treatment | Research | Myeloproliferative disorders | Cancer | Index Medicus | tyrosine kinase inhibitors | persistence | MPN | JAK2 | resistance
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e59675 - e59675
Germline deletion of Jak2 in mice results in embryonic lethality at E12.5 due to impaired hematopoiesis... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Organ Specificity - drug effects | Humans | Hematopoietic Stem Cells - pathology | Anemia - pathology | Hematopoiesis - drug effects | Embryo Loss - pathology | Gene Deletion | Female | Spleen - pathology | Janus Kinase 2 - antagonists & inhibitors | Animals, Newborn | Hematopoietic Stem Cells - drug effects | Myeloid Progenitor Cells - metabolism | Embryonic Development - genetics | Janus Kinase 2 - genetics | Hematopoiesis - genetics | Hematopoietic Stem Cells - metabolism | Myeloid Progenitor Cells - pathology | Aging - pathology | Blood Cell Count | Mice, Knockout | Pregnancy | Lymphocytes - pathology | Animals | Myeloid Progenitor Cells - drug effects | Lymphocytes - drug effects | Survival Analysis | Tamoxifen - pharmacology | Mice | Embryonic Development - drug effects | Interferon Regulatory Factor-1 - metabolism | GTP-Binding Proteins - metabolism | Embryonic development | B cells | Pregnant women | Analysis | Heart | Erythropoiesis | Pediatrics | Lymphopoiesis | Thrombopoiesis | Genomics | Leukemia | Lethality | Ontogeny | Gestation | Kinases | Atrophy | Red blood cells | Granulocytes | Clonal deletion | Hematopoiesis | Rodents | Janus kinase 2 | Bone marrow | Physiology | Inhibition | Spleen | Phenotypes | Kidneys | Young adults | Cytokines | Anemia | Mortality | Organs | Embryos | Hemopoiesis | Mutants | Medicine | Lungs | Alleles | Stem cells | Death | Adults | Mutation | Survivability | Granulopoiesis | Index Medicus
Journal Article