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European Journal of Immunology, ISSN 0014-2980, 04/2018, Volume 48, Issue 4, pp. 655 - 669
The presence of the PTPN22 risk allele (1858T) is associated with several autoimmune diseases including rheumatoid arthritis (RA). Despite a number of studies... 
T cells | Perforin‐1 | CD4 | cytotoxic T lymphocytes | 4‐1BB | Rheumatoid Arthritis (RA) | 4-1BB | Perforin-1 | T-Lymphocytes, Cytotoxic - immunology | Humans | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics | 4-1BB Ligand - biosynthesis | CASP8 and FADD-Like Apoptosis Regulating Protein - biosynthesis | T-Box Domain Proteins - metabolism | Arthritis, Rheumatoid - pathology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - immunology | Arthritis, Rheumatoid - genetics | Sequence Analysis, RNA | Base Sequence | Receptors, Antigen, T-Cell - immunology | Synovial Fluid - cytology | T-Lymphocytes, Cytotoxic - cytology | Perforin - biosynthesis | RNA sequencing | Rheumatoid factor | Arthritis | T cells | Cell differentiation | Pathogenesis | Helper cells | Differentiation (biology) | Cytotoxicity | Risk | Lymphocytes T | Ribonucleic acid--RNA | CD4 antigen | Gene sequencing | Carriers | T-cell receptor | Synovial fluid | Cell activation | Lymphocytes | Rheumatoid arthritis | Alleles | Perforin | Autoimmune diseases | Protein-tyrosine-phosphatase | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Medicinsk vetenskap | CD4+ T cells | Klinisk medicin | Rheumatology and Autoimmunity | Clinical Medicine | Medical Science | Cytotoxic T lymphocytes
Journal Article
Journal Article
Inflammation Research, ISSN 1023-3830, 9/2017, Volume 66, Issue 9, pp. 775 - 781
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 1084
BackgroundMutations in the protein tyrosine phosphatase non-receptor 22 (PTPN22) gene are associated with numerous connective tissue and autoimmune diseases... 
Tyrosine | Transcription | Genomes | Single-nucleotide polymorphism | Inflammation | Gene expression | Gene polymorphism | Risk factors | Genotyping | Rheumatoid arthritis | Alleles | Down-regulation | Peripheral blood | Histocompatibility antigen HLA | Mutation | Cardiovascular diseases | Health risk assessment | Autoimmune diseases | Protein-tyrosine-phosphatase
Journal Article
Diabetes, ISSN 0012-1797, 03/2013, Volume 62, Issue 3, pp. 896 - 904
Journal Article
PLoS One, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e31230
Background: Behcet's disease is known as a recurrent, multisystem inflammation and immune-related disease. Protein tyrosine phosphatase non-receptor 22... 
RHEUMATOID-ARTHRITIS | IL10 | JAPANESE POPULATION | MULTIDISCIPLINARY SCIENCES | IL23R-IL12RB2 | TYROSINE-PHOSPHATASE PTPN22 | AUTOIMMUNE-DISEASE | GENE POLYMORPHISMS | VARIANT | GENOME-WIDE ASSOCIATION | SILK ROAD | Genetic Predisposition to Disease | Eye Diseases - ethnology | Gene Frequency | Humans | Middle Aged | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics | Genotype | Male | Case-Control Studies | Polymorphism, Genetic | Behcet Syndrome - ethnology | Eye Diseases - genetics | Immune System | Polymorphism, Restriction Fragment Length | China | Adolescent | Polymerase Chain Reaction | Adult | Female | Aged | Behcet Syndrome - genetics | Tyrosine | Medical research | Phosphatases | Analysis | Genes | Medicine, Experimental | Disease susceptibility | Genetic aspects | Single nucleotide polymorphisms | T cells | Behcet's syndrome | Haplotypes | Multiple sclerosis | Populations | Laboratories | Pathogenesis | Lymphocytes T | Single-nucleotide polymorphism | Kinases | Phosphatase | Proteins | Lymphocytes | Rheumatology | Inflammation | Regression analysis | Disease control | Patients | Minority & ethnic groups | Crohns disease | Polymerase chain reaction | Hospitals | Restriction fragment length polymorphism | Gene frequency | Rheumatoid arthritis | Diabetes | Autoimmune diseases | Health risk assessment | Protein-tyrosine-phosphatase | Polymorphism
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 09/2019, Volume 197, Issue 3, pp. 263 - 275
Interleukin (IL)‐10 plays a key role in controlling intestinal inflammation. IL‐10 ‐deficient mice and patients with mutations in IL‐10 or its receptor, IL‐10R... 
PTPN22 | colitis | IL‐10 | inflammatory bowel diseases (IBD) | SUSCEPTIBILITY | KINASE | INDUCTION | IMMUNOLOGY | IL-10 | MOUSE MODELS | PATHOGENESIS | AUTOIMMUNITY | REGULATORY T-CELLS | PEP | TYROSINE-PHOSPHATASE PTPN22 | ASSOCIATION | Dextran | Disease susceptibility | Phosphatases | Colitis | T cells | Gastrointestinal diseases
Journal Article