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1981, ISBN 9155411177, 46
Book
Current issues in pharmacy and medicine: science and practice, ISSN 2306-8094, 06/2019, Volume 12, Issue 2, pp. 166 - 171
The aim of the work is devoted to the substantiation of the choice of excipients while the development of Cardiosten tablets with a dry extract from a mixture... 
s/100g; mass loss during wetting and granulation | the following substances were selected as further objects: Prosolv HD 90 (vehicle) | structure-forming substances (disintegrating agents) | the influence of auxiliary substances on the technological properties of the granules with dry extract “Cardiosten” and tablets obtained from these granules was investigated. Fillers | taking into account the application of the mathematical planning of the experiment. Materials and methods. Using the method of mathematical planning of the experiment (MPE) | HPMC solution (binding agent). Keywords tablets; plant extract; mathematical planning of the experiment; excipients | disintegration of tablets | the qualitative composition of auxiliary substances for the production of tablets by the method of wet granulation - Prosolv HD 90 (filler) was determined | N. Results. In the course of the conducted research | Neosorb –100 (sorbent) | min | Ye. V. Hladukh Abstract The aim of the work is devoted to the substantiation of the choice of excipients while the development of Cardiosten tablets with a dry extract from a mixture of medicinal plant materials of cardiological action | sorbents (moisture regulators) | and resistance of tablets to crushing | plant extract | weight loss) and tablets (disintegration time of tablets | the dependence of all responses on the above factors was determined according to the technological parameters of the tablet mass and finished tablets. Based on the analysis of the most effective levels of factors that had the maximum effect on the responses | excipients | the most optimal excipients were selected for the production of tablets with a dry extract content of “Cardiosten”. Based on the indicators of pelletized mass (bulk density | resistance of tablets to crushing | polyplasdon XL10 (structuring agent) and HPMC solution as a binder. Conclusions. Using the MPE method | which were investigated by the four-factor experiment method based on a Greek-Latin square. The following indicators of granules and tablets based on dry extract “Cardiosen” were used as responses: bulk density g/cm3; mass flow for tableting | polyplasdon XL10 (structuring agent) | abrasion of tablets | mathematical planning of the experiment | bulk flow | tablets | binding substances and calcium stearate as a powdering agent (antifriction substance) were used as excipients. All groups of excipients (except calcium stearate) were divided into levels of factors | Neosorb – 100 (sorbent)
Journal Article
Drug Development and Industrial Pharmacy, ISSN 0363-9045, 2009, Volume 35, Issue 6, pp. 671 - 677
Journal Article
1968, 2d ed. --, 155 p., [13] leaves of plates
Book
1968, Pharmaceutical monographs, v. 8., vii, 70
Book
2012, Berliner Beiträge zum Vorderen Orient, ISBN 3935012098, Volume Band 22, 100 p., 36 p. of plates
Book
1968, Università degli studi di Padova. Pubblicazioni dell'Istituto di storia antica, v. 7, 237
Book
1965, Note e discussioni erudite, Volume 10, 43 p., [6] leaves of plates
Book
Book
Book
1949, Liverpool, Eng.
Book
2012, Ausgrabungen der Deutschen Orient-Gesellschaft in Assur. E, Inschriften, ISBN 3447068124, Volume Heft 130., vii, 78 p., [32] p. of plates
Book
Book
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