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1. Full Text Tachykinins and their receptors: Contributions to physiological control and the mechanisms of disease
by Steinhoff, Martin S and von Mentzer, Bengt and Geppetti, Pierangelo and Pothoulakis, Charalabos and Bunnett, Nigel W
Physiological Reviews, ISSN 0031-9333, 01/2014, Volume 94, Issue 1, pp. 265 - 301
The tachykinins, exemplified by substance P, are one of the most intensively studied neuropeptide families. They comprise a series of structurally related... 
GENERAL-ANESTHETICS ACTIVATE | PHYSIOLOGY | CHEMOTHERAPY-INDUCED NAUSEA | MESSENGER-RNA EXPRESSION | PROTEIN-COUPLED RECEPTOR | NEUROKININ 1 RECEPTOR | MICROVASCULAR ENDOTHELIAL-CELLS | STIMULATED INTERLEUKIN-8 EXPRESSION | NF-KAPPA-B | COLONIC EPITHELIAL-CELLS | SUBSTANCE-P RECEPTOR | Receptors, Tachykinin - genetics | Animals | Tachykinins - genetics | Tachykinins - metabolism | Urinary Bladder - metabolism | Receptors, Tachykinin - metabolism | Humans | Muscle Contraction - physiology | Urinary Bladder - physiopathology | Intestines - metabolism | Muscle, Smooth - metabolism | Tachykinins | Physiological aspects | Italy | Research | Australia | Health aspects | Diseases
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2. Full Text New challenges in the study of the mammalian tachykinins
by Page, Nigel M
Peptides, ISSN 0196-9781, 2005, Volume 26, Issue 8, pp. 1356 - 1368
There is an expanding repertoire of mammalian tachykinins produced by a variety of tachykinin genes, gene splicing events and peptide processing. Novel... 
Endokinin | Tachykinin NK 1 receptor | Neurokinin | Receptor | Substance P | Long | Isoform | Hemokinin | Virokinin | Tachykinin | Peptide | Short | Tachykinin NK | short isoform | peptide | tachykinin NK1 receptor | BIOCHEMISTRY & MOLECULAR BIOLOGY | neurokinin | HIGH-AFFINITY | virokinin | NEUROPEPTIDE-GAMMA | endokinin | long | hemokinin tachykinin | MESSENGER-RNAS | receptor | HUMAN NEUROKININ-3 RECEPTOR | PORCINE SPINAL-CORD | FUNCTIONAL EXPRESSION | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGICAL PROFILE | PHARMACOLOGY & PHARMACY | NK1 RECEPTOR | substance P | BINDING-SITES | SUBSTANCE-P RECEPTOR | Receptors, Tachykinin - genetics | Amino Acid Sequence | Peptide Fragments - metabolism | Tachykinins - metabolism | Receptors, Tachykinin - metabolism | Humans | Molecular Sequence Data | Alternative Splicing - physiology | Peptide Fragments - physiology | Animals | Tachykinins - genetics | Peptide Fragments - genetics | Receptors, Tachykinin - physiology | Tachykinins - physiology | Tachykinins
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3. The Tachykinin receptors
by Buck, Stephen H
1994, The Receptors, ISBN 9780896032668, xi, 630
Receptors | Tachykinins
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4. Overview of the primary structure, tissue-distribution, and functions of tachykinins and their receptors
by Satake, Honoo and Kawada, Tsuyoshi
Current Drug Targets, ISSN 1389-4501, 08/2006, Volume 7, Issue 8, pp. 963 - 974
Tachykinins (TKs) constitute the largest vertebrate brain/gut peptide family. Since discovery of Substance P as a structurally unidentified vasodilatory and... 
Signal transduction | Activity | Receptor | Tachykinin | Conformation | LOCUST CORPORA-CARDIACA | activity | signal transduction | YELLOW-FEVER MOSQUITO | NK-1 RECEPTOR | conformation | NEUROKININ-A | AMINO-ACID SEQUENCE | NEUROPEPTIDES SUBSTANCE-P | tachykinin | receptor | HAMSTER OVARY CELLS | PORCINE SPINAL-CORD | PHARMACOLOGY & PHARMACY | MAIN ACTIVE POLYPEPTIDE | NK1 RECEPTOR | Receptors, Tachykinin - genetics | Tissue Distribution - physiology | Tachykinins - chemistry | Tachykinins - metabolism | Receptors, Tachykinin - metabolism | Humans | Molecular Sequence Data | Amino Acid Sequence - genetics | Animals | Tachykinins - genetics | Receptors, Tachykinin - chemistry | Receptors, Tachykinin - physiology | Tachykinins - physiology
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5. Full Text Hemokinins and endokinins
by Page, N M
Cellular and Molecular Life Sciences, ISSN 1420-682X, 6/2004, Volume 61, Issue 13, pp. 1652 - 1663
The mammalian tachykinins are a family of peptides that, until recently, has included substance P (SP), neurokinin A and neurokinin B. Since, the discovery of... 
Endokinin | peptide | neurokinin | TAC4 | LifeSciences | hemokinin | tachykinin | Hemokinin | Neurokinin | Peptide | Tachykinin | TACHYKININ NK1 RECEPTOR | GAMMA-PREPROTACHYKININ | SUBSTANCE-P PRECURSOR | MAMMALIAN TACHYKININ | NEUROKININ-B | endokinin | HYPOTHALAMIC TISSUE | PORCINE SPINAL-CORD | PHARMACOLOGICAL PROFILE | NEUROMEDIN-K | SALIVARY SECRETION | Protein Precursors - agonists | Amino Acid Sequence | Tachykinins - chemistry | Protein Precursors - genetics | Tachykinins - metabolism | Protein Precursors - chemistry | Receptors, Tachykinin - metabolism | Humans | RNA, Messenger - genetics | RNA, Messenger - analysis | Protein Precursors - metabolism | Protein Transport | Animals | Tachykinins - agonists | Tachykinins - genetics | Evolution, Molecular | Peptides
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6. Full Text The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress
by Zelikowsky, Moriel and Hui, May and Karigo, Tomomi and Choe, Andrea and Yang, Bin and Blanco, Mario R and Beadle, Keith and Gradinaru, Viviana and Deverman, Benjamin E and Anderson, David J
Cell, ISSN 0092-8674, 05/2018, Volume 173, Issue 5, pp. 1265 - 1279.e19
Chronic social isolation causes severe psychological effects in humans, but their neural bases remain poorly understood. 2 weeks (but not 24 hr) of social... 
social isolation | stress | amygdala | BNST | NkB | neuropeptides | Nk3R | Tac2 | aggression | DMH | fear | CEREBRAL HEMISPHERE INTEGRATION | FACTOR REVEALS | CORTICOTROPIN-RELEASING-FACTOR | NK3 RECEPTOR | STRIA TERMINALIS | ANXIETY | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURAL CIRCUITS | MICE | BED NUCLEI | AMYGDALA | CELL BIOLOGY | RNA, Small Interfering - genetics | Tachykinins - antagonists & inhibitors | Genetic Vectors - administration & dosage | Receptors, Tachykinin - metabolism | Male | Neurons - cytology | Neurokinin B - genetics | Brain - metabolism | Protein Precursors - antagonists & inhibitors | Protein Isoforms - metabolism | Tachykinins - genetics | RNA Interference | Receptors, Tachykinin - antagonists & inhibitors | Behavior, Animal - drug effects | Female | Neurons - metabolism | Social Isolation | Protein Precursors - genetics | Tachykinins - metabolism | Mice, Inbred C57BL | Genetic Vectors - genetics | Neurokinin B - metabolism | Protein Precursors - metabolism | Up-Regulation - drug effects | Animals | Brain - pathology | Stress, Psychological | Mice | Mice, Inbred BALB C | Antipsychotic Agents - pharmacology | Protein Isoforms - genetics | Neuropeptides | Neurosciences | Analysis
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7. Full Text The evolution of tachykinin/tachykinin receptor (TAC/TACR) in vertebrates and molecular identification of the TAC3/TACR3 system in zebrafish (Danio rerio)
by Zhou, Wenyi and Li, Shuisheng and Liu, Xiaochun and Liu, Yun and Qi, Xin and Chen, Huapu and Cheng, Christopher H.K and Zhang, Yong and Lin, Haoran
Molecular and Cellular Endocrinology, ISSN 0303-7207, 09/2012, Volume 361, Issue 1-2, pp. 202 - 212
► Five TAC and six TACR genes were identified in teleost. ► The teleostean evolutionary history of TAC and TACR genes was clarified. ► Full length of zebrafish... 
TAC gene | Zebrafish | TACR gene | TAC3/TACR3 system | Evolutionary history | CHROMOSOME LOCALIZATION | WHOLE-GENOME DUPLICATION | ARCUATE NUCLEUS | NEUROKININ-B | KISSPEPTIN NEURONS | CELL BIOLOGY | HUMAN SUBSTANCE-P | FUNCTIONAL EXPRESSION | SEQUENCE ALIGNMENT | DYNORPHIN-A | ENDOCRINOLOGY & METABOLISM | MAMMALIAN TACHYKININ RECEPTORS | Receptors, Tachykinin - genetics | Tachykinins - chemistry | Receptors, Tachykinin - metabolism | Humans | Genome - genetics | Cercopithecus aethiops | Molecular Sequence Data | Gene Expression Profiling | Phylogeny | Promoter Regions, Genetic - genetics | Tachykinins - genetics | Base Sequence | Protein Binding - drug effects | Cloning, Molecular | Real-Time Polymerase Chain Reaction | Amino Acid Sequence | Synteny - genetics | Tachykinins - metabolism | Zebrafish Proteins - chemistry | Zebrafish Proteins - metabolism | Zebrafish - genetics | Peptides - pharmacology | Gene Expression Regulation - drug effects | Sequence Homology, Amino Acid | Animals | Receptors, Tachykinin - chemistry | Zebrafish Proteins - genetics | COS Cells | Evolution, Molecular | Anopheles | Pituitary hormones | Peptides | Biological control | Genes | Neurohormones | Animal genetic engineering | Pests | Brain | Vertebrates | Receptors | Genomes
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8. Tachykinins and tachykinin receptors: Structure and activity relationships
by Almeida, T.A and Rojo, J and Nieto, P.M and Pinto, F.M and Hernandez, M and Martín, J.D and Candenas, M.L
Current Medicinal Chemistry, ISSN 0929-8673, 2004, Volume 11, Issue 15, pp. 2045 - 2081
In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide number of peptides with neurotransmitter activity have been identified... 
Tachykinin receptors | Hemokinin-1 | Neurokinin B | Substance P | Tachykinins | HUMAN NEUROKININ-1 RECEPTOR | CHEMISTRY, MEDICINAL | VASOACTIVE-INTESTINAL-PEPTIDE | SENSITIVE SENSORY NEURONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-COUPLED RECEPTORS | tachykinins | RAT URINARY-BLADDER | SITE-DIRECTED MUTAGENESIS | hemokinin-1 | neurokinin A | C-TERMINAL HEXAPEPTIDE | PHARMACOLOGY & PHARMACY | tachykinin receptors | CENTRAL-NERVOUS-SYSTEM | substance P | INDUCED AIRWAY HYPERRESPONSIVENESS | neurokinin B | SUBSTANCE-P RECEPTOR | Amino Acid Sequence | Tachykinins - chemistry | Animals | Humans | Receptors, Tachykinin - chemistry | Molecular Sequence Data | Structure-Activity Relationship | Receptors, Tachykinin - physiology | Tachykinins - physiology
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9. Full Text Natalisin, a tachykinin-like signaling system, regulates sexual activity and fecundity in insects
by Hongbo Jiang and Ankhbayar Lkhagva and Ivana Daubnerová and Hyo-Seok Chae and Ladislav Šimo and Sung-Hwan Jung and Yeu-Kyung Yoon and Na-Rae Lee and Jae Young Seong and Dušan Žitňan and Yoonseong Park and Young-Joon Kim
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 09/2013, Volume 110, Issue 37, pp. E3526 - E3534
An arthropod-specific peptidergic system, the neuropeptide designated here as natalisin and its receptor, was identified and investigated in three... 
NTLR | CG6515 | GPCR | CG34388 | NTL | TRIBOLIUM-CASTANEUM | RED FLOUR BEETLE | DROSOPHILA-MELANOGASTER | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | FAMILY | PEPTIDES | GENES | NEUROPEPTIDE RECEPTORS | NEURONS | Receptors, Tachykinin - genetics | Drosophila melanogaster - physiology | Tachykinins - antagonists & inhibitors | Molecular Sequence Data | Male | Neuropeptides - physiology | Phylogeny | Drosophila melanogaster - genetics | Fertility - physiology | Brain - metabolism | Sexual Behavior, Animal - physiology | Drosophila Proteins - physiology | Fertility - genetics | Tachykinins - genetics | RNA Interference | Tribolium - physiology | Conserved Sequence | Female | Insecta - physiology | Neuropeptides - genetics | Drosophila Proteins - antagonists & inhibitors | Amino Acid Sequence | Brain - cytology | Insect Proteins - physiology | Signal Transduction | Bombyx - physiology | Insect Proteins - genetics | Bombyx - genetics | Insecta - genetics | Insect Proteins - antagonists & inhibitors | Animals | Interneurons - metabolism | Tribolium - genetics | Drosophila Proteins - genetics | Neuropeptides - antagonists & inhibitors | Receptors, Tachykinin - physiology | Tachykinins - physiology | Life Sciences | Biological Sciences | PNAS Plus
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10. Full Text A role for tachykinins in the regulation of human sperm motility
by Ravina, C.G and Seda, M and Pinto, F.M and Orea, A and Fernández-Sánchez, M and Pintado, C.O and Candenas, M.Luz
Human Reproduction, ISSN 0268-1161, 06/2007, Volume 22, Issue 6, pp. 1617 - 1625
BACKGROUND Tachykinins and tachykinin receptors are widely distributed in the male reproductive tract and appear to be involved in reproduction. However, the... 
Tachykinin receptors | Human sperm | Tachykinins | mRNA expression | LOCALIZATION | MOUSE | tachykinins | SPERMATOZOAL RNA | OBSTETRICS & GYNECOLOGY | human sperm | REPRODUCTIVE BIOLOGY | MESSENGER-RNA | ENDOKININS | PITUITARY | tachykinin receptors | SUBSTANCE-P | RECEPTORS | PROTEINS | EXPRESSION | Immunohistochemistry | Sperm Motility | Spermatozoa - chemistry | Neurokinin B - physiology | Receptors, Tachykinin - metabolism | Humans | Quinuclidines - pharmacology | Neurokinin A - physiology | Male | Substance P - pharmacology | Tachykinins - pharmacology | Neurokinin B - pharmacology | Spermatozoa - drug effects | Receptors, Tachykinin - analysis | Tachykinins - genetics | Piperidines - pharmacology | Receptors, Tachykinin - antagonists & inhibitors | Substance P - physiology | Spermatozoa - physiology | Benzamides - pharmacology | Neurokinin A - pharmacology | Tachykinins - physiology
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11. Full Text The Tachykinin Peptide Family
by Cinzia Severini and Giovanna Improta and Giuliana Falconieri-Erspamer and Severo Salvadori and Vittorio Erspamer
Pharmacological Reviews, ISSN 0031-6997, 06/2002, Volume 54, Issue 2, pp. 285 - 322
The tachykinin peptide family certainly represents one of the largest peptide families described in the animal organism. So far, more than 40 tachykinins have... 
A-LIKE IMMUNOREACTIVITY | AMYLOID BETA-PROTEIN | GENE-RELATED PEPTIDE | CONTAINING NEURON SYSTEM | CRAB CANCER-BOREALIS | CIONA-INTESTINALIS L | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | EARTHWORM LUMBRICUS-TERRESTRIS | PRIMARY SENSORY NEURONS | SUBSTANCE-P-LIKE | Receptors, Tachykinin - agonists | Amino Acid Sequence | Animals | Tachykinins - genetics | Species Specificity | Humans | Receptors, Tachykinin - antagonists & inhibitors | Molecular Sequence Data | Tachykinins - pharmacology | Tachykinins - physiology
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12. Full Text Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending Regulation
by Gao, Zheng-Run and Chen, Xiao-Jun and Chen, Wen-Zhen and Liu, Ming-Zhe and Wan, Li and Zhang, Xin-Yan and Yuan, Lei and Lin, Jun-Kai and Wang, Meng and Zhou, Li and Xu, Xiao-Hong and Sun, Yan-Gang
Neuron, ISSN 0896-6273, 01/2019, Volume 101, Issue 1, pp. 45 - 59.e9
Uncontrollable itch-scratching cycles lead to serious skin damage in patients with chronic itch. However, the neural mechanism promoting the itch-scratching... 
extracellular recording | itch | somatostatin | optogenetics | grooming | rostral ventromedial medulla | spinal cord | Tac1 | GRPR | periaqueductal gray | CIRCUITS | DORSAL-HORN NEURONS | PAIN | RAT | ELECTRICAL-STIMULATION | SPINAL-CORD | ROSTRAL VENTROMEDIAL MEDULLA | PEPTIDERGIC ORGANIZATION | NEUROSCIENCES | BRAIN | ANALGESIA | Pyramidal Tracts - chemistry | Gene Expression | Neurons - chemistry | Mice, Inbred C57BL | Male | Mice, Transgenic | Periaqueductal Gray - chemistry | Random Allocation | Tachykinins - biosynthesis | Periaqueductal Gray - metabolism | Pruritus - metabolism | Animals | Tachykinins - genetics | Pyramidal Tracts - metabolism | Receptors, Neurokinin-1 - biosynthesis | Mice | Neurons - metabolism | Neurokinin A - biosynthesis | Neurokinin A - genetics | Pruritus - pathology | Receptors, Neurokinin-1 - genetics | Neurosciences | Pruritus | Neurons | Gastrin | Tachykinin receptors | Scratching behavior | Data analysis | Spinal cord | Statistical analysis | Periaqueductal gray area | Experiments | Gastrin-releasing peptide | Pain | Grooming | Signal processing | Software | Skin | Behavior | Glutamatergic transmission | Tachykinin
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13. Full Text Hemokinin-1(4-11)-induced analgesia selectively up- regulates δ-opioid receptor expression in mice
by Fu, Cai-Yun and Xia, Rui-Long and Zhang, Teng-Fei and Lu, Yan and Zhang, Shi-Fu and Yu, Zhi-Qiang and Jin, Tao and Mou, Xiao-Zhou
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e90446
Our previous studies have shown that an active fragment of human tachykinins (hHK-1(4-11)) produced an opioid-independent analgesia after... 
SUPRASPINAL LEVEL | CARDIOVASCULAR-RESPONSES | MESSENGER-RNA | PERIAQUEDUCTAL GRAY | FUNCTIONAL EXPRESSION | MULTIDISCIPLINARY SCIENCES | IN-SITU HYBRIDIZATION | RAT/MOUSE HEMOKININ-1 | PHARMACOLOGICAL PROFILE | MAMMALIAN TACHYKININ PEPTIDE | ANESTHETIZED RATS | Receptors, Opioid, delta - metabolism | Tachykinins - chemistry | Gene Expression - drug effects | Humans | Injections, Intraventricular | Male | Peptide Fragments - pharmacology | Tachykinins - pharmacology | Tachykinins - administration & dosage | Tachykinins - genetics | Receptors, Opioid, delta - genetics | Female | Pro-Opiomelanocortin - genetics | Protein Precursors - genetics | Tachykinins - metabolism | Receptors, Opioid, mu - metabolism | Peptide Fragments - administration & dosage | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Inbred ICR | Protein Precursors - metabolism | Pro-Opiomelanocortin - metabolism | Up-Regulation - drug effects | Analgesia | Animals | Receptors, Opioid, mu - genetics | Brain | Pain perception | Polypeptides | Transcription | Narcotics | Opioid receptors | Cloning | Central nervous system | Pharmacology | Proopiomelanocortin | Injection | Gene expression | Receptors | Analgesics | Rodents