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The New England Journal of Medicine, ISSN 0028-4793, 12/2007, Volume 357, Issue 25, pp. 2562 - 2575
This study examines the toxicity of immunosuppressive regimens in renal-transplant recipients. A regimen containing mycophenolate mofetil, daclizumab, low-dose... 
MULTICENTER TRIAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE MICROEMULSION | EFFICACY | KIDNEY-TRANSPLANTATION | IMMUNOSUPPRESSION | ALLOGRAFT RECIPIENTS | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | NEPHROTOXICITY | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Enzyme Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized | Calcineurin Inhibitors | Treatment Failure | Adult | Diabetes Mellitus - etiology | Female | Drug Therapy, Combination | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Glomerular Filtration Rate | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Kidney Transplantation | Immunoglobulin G - administration & dosage | Opportunistic Infections | Sirolimus - administration & dosage | Mycophenolic Acid - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Cyclosporine - administration & dosage | Immunosuppressive Agents - adverse effects | Aged | Adrenal Cortex Hormones - administration & dosage | Transplantation | Corticosteroids | Kidneys | Research | Health aspects | Immunosuppressive agents | Medical research | Immunology | Inhibitor drugs | Transplants & implants | Toxicity | Index Medicus | Abridged Index Medicus | Inhibidors enzimàtics | Posologia | Ús terapèutic | Corticosteroides | Rebuig (Biologia) | Posology | Therapeutic use | Immunosupressive agents | Graft rejection | Trasplantament renal | Enzyme inhibitors | Adrenocortical hormones | Immunosupressors | Kidney transplantation | Tacrolimus: administration & dosage | Medical and Health Sciences | Graft Rejection: prevention & control | Immunoglobulin G: administration & dosage | Medicin och hälsovetenskap | Mycophenolic Acid: administration & dosage | Antibodies | Klinisk medicin | Monoclonal: administration & dosage | Prednisone: administration & dosage | Adrenal Cortex Hormones: administration & dosage | Immunosuppressive Agents: administration & dosage | Mycophenolic Acid: analogs & derivatives | Sirolimus: administration & dosage | Cyclosporine: administration & dosage | Calcineurin: antagonists & inhibitors | Diabetes Mellitus: etiology | Urologi och njurmedicin | Sirolimus: adverse effects | Adrenal Cortex Hormones: therapeutic use | Enzyme Inhibitors: administration & dosage | Immunosuppressive Agents: adverse effects | Clinical Medicine | Immunosuppressive Agents: therapeutic use | Urology and Nephrology
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2012, Volume 161, Issue 3, pp. 735 - 745
The objective of the present study was to investigate the effect of polyarginine chain length on topical delivery of surface modified NLCs. Design of... 
Nanostructured lipid carriers (NLC) | Cell penetrating peptide (CPP) | Polyarginine peptide | Skin delivery | Allergic contact dermatitis (ACD) | DRUG-DELIVERY | CHITOSAN CROSS-LINKING | TRANSDERMAL DELIVERY | MEFLOQUINE HYDROCHLORIDE MICROPARTICLES | CELL-PENETRATING PEPTIDES | TACROLIMUS OINTMENT | CHEMISTRY, MULTIDISCIPLINARY | DERMAL DELIVERY | PHARMACOLOGY & PHARMACY | H-II MESOPHASES | SUBSTANCE-P | SPANTIDE-II | Nanoparticles - chemistry | Drug Carriers - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Drug Carriers - chemistry | Peptides - administration & dosage | Ketoprofen - chemistry | Allergens - administration & dosage | Lipids - chemistry | Rats, Hairless | Skin Absorption - drug effects | Substance P - analogs & derivatives | Oligopeptides - chemistry | Cell-Penetrating Peptides - chemistry | Dermatitis, Allergic Contact - drug therapy | Peptides - chemistry | Mice, Inbred C57BL | Ketoprofen - administration & dosage | Rats | Lipids - administration & dosage | Dinitrofluorobenzene - administration & dosage | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Mice | Nanoparticles - administration & dosage | Oligopeptides - administration & dosage | Cell-Penetrating Peptides - administration & dosage | Administration, Topical | Substance P - chemistry | Substance P - administration & dosage | Usage | Peptides | Dermatology | Analysis | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Raman spectroscopy | Transdermal medication | Index Medicus | polyarginine peptide | cell penetrating peptide (CPP) | nanostructured lipid carriers (NLC) | allergic contact dermatitis (ACD)
Journal Article
Journal Article
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 05/2015, Volume 15, Issue 5, pp. 1313 - 1322
The authors describe the drug–drug interaction profile of the he patitis C direct‐acting antiviral agents ABT‐450, ombitasvir, and dasabuvir with cyclosporine... 
infectious disease | clinical research/practice | pharmacology | calcineurin inhibitor: cyclosporine A (CsA) | pharmacokinetics/pharmacodynamics | immunosuppressant | infection and infectious agents | calcineurin inhibitor: tacrolimus | liver transplantation/hepatology | viral: hepatitis C | SURGERY | ABT-450/R-OMBITASVIR | LIVER-TRANSPLANTATION | EFFICACY | DRUG-INTERACTIONS | TRANSPORTERS | INFECTION | HCV | RIBAVIRIN | INHIBITOR | HEPATITIS-C | TRANSPLANTATION | Antiviral Agents - pharmacokinetics | Hepatitis C - drug therapy | Area Under Curve | Humans | Middle Aged | Male | Anilides - pharmacokinetics | Carbamates - administration & dosage | Healthy Volunteers | Carbamates - pharmacokinetics | Young Adult | Uracil - administration & dosage | Cyclosporine - pharmacokinetics | Adult | Female | Tacrolimus - administration & dosage | Hepacivirus - drug effects | Drug Administration Schedule | Macrocyclic Compounds - pharmacokinetics | Tacrolimus - pharmacokinetics | Antiviral Agents - administration & dosage | Sulfonamides - pharmacokinetics | Anilides - administration & dosage | Adolescent | Cyclosporine - administration & dosage | Macrocyclic Compounds - administration & dosage | Uracil - pharmacokinetics | Sulfonamides - administration & dosage | Uracil - analogs & derivatives | Dosage and administration | Liver diseases | Drug therapy, Combination | Tacrolimus | Hepatitis C virus | Hepatitis C | Hepatitis | Medical research | Drug dosages | Index Medicus | practice | pharmacodynamics | hepatology | clinical research | pharmacokinetics | Original | liver transplantation
Journal Article
Journal Article
Liver Transplantation, ISSN 1527-6465, 07/2013, Volume 19, Issue 7, pp. 690 - 700
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 05/2018, Volume 58, Issue 5, pp. 666 - 673
Elbasvir (EBR)/grazoprevir (GZR) may be coadministered with immunosuppressant drugs in posttransplant people who are infected with hepatitis C virus. The aim... 
cyclosporine | drug‐drug interactions | tacrolimus | pharmacokinetics | grazoprevir | mycophenolate mofetil | prednisone | elbasvir | drug-drug interactions | EFFICACY | GRAZOPREVIR MK-5172 | SAFETY | COMBINATION THERAPY | LABEL PHASE-2 TRIAL | RIBAVIRIN | HEPATITIS-C VIRUS | GENOTYPE 1 INFECTION | PHARMACOLOGY & PHARMACY | ELBASVIR MK-8742 | TREATMENT-NAIVE PATIENTS | Quinoxalines - adverse effects | Antiviral Agents - pharmacokinetics | Area Under Curve | Humans | Immunosuppressive Agents - pharmacokinetics | Middle Aged | Imidazoles - administration & dosage | Benzofurans - administration & dosage | Male | Imidazoles - pharmacokinetics | Benzofurans - pharmacokinetics | Young Adult | Drug Interactions | Cyclosporine - pharmacokinetics | Adult | Female | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Quinoxalines - pharmacokinetics | Prednisone - adverse effects | Quinoxalines - administration & dosage | Administration, Oral | Imidazoles - adverse effects | Mycophenolic Acid - pharmacokinetics | Tacrolimus - pharmacokinetics | Tacrolimus - adverse effects | Antiviral Agents - administration & dosage | Benzofurans - adverse effects | Mycophenolic Acid - adverse effects | Antiviral Agents - adverse effects | Cyclosporine - adverse effects | Cyclosporine - administration & dosage | Prednisone - pharmacokinetics | Immunosuppressive Agents - adverse effects | Drug Combinations | Drugs | Mycophenolic acid | Cyclosporins | Transaminase | Viruses | Prednisone | Pharmacology | Hepatitis | Tacrolimus | Mycophenolate mofetil | Hepatitis C virus | Pharmacokinetics | Hepatitis C | Drug dosages | Prednisolone | Index Medicus
Journal Article
Transplantation, ISSN 0041-1337, 12/2005, Volume 80, Issue 12, pp. 1734 - 1741
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2008, Volume 14, Issue 6, pp. 641 - 650
Abstract We evaluated the safety and efficacy of high-dose, posttransplantation cyclophosphamide (Cy) to prevent graft rejection and graft-versus-host disease... 
Hematology, Oncology and Palliative Medicine | Bone marrow transplantation | Cyclophosphamide | Histocompatibility antigens | Conditioning regimens | Lymphoma | Leukemia | TOTAL-BODY IRRADIATION | leukemia | IMMUNE RECONSTITUTION | lymphoma | UNRELATED DONORS | ACUTE MYELOID-LEUKEMIA | IMMUNOLOGY | VERSUS-HOST-DISEASE | bone marrow transplantation | TRANSPLANTATION | histocompatibility antigens | CORD BLOOD TRANSPLANTATION | DRUG-INDUCED TOLERANCE | IDENTICAL SIBLINGS | cyclophosphamide | STEM-CELL TRANSPLANTATION | HEMATOLOGY | MYCOPHENOLATE-MOFETIL | conditioning regimens | Whole-Body Irradiation | Cyclophosphamide - administration & dosage | Graft vs Host Disease - epidemiology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Recombinant Proteins | Bone Marrow Transplantation - methods | Cyclophosphamide - therapeutic use | Filgrastim | Transplantation, Homologous | Bone Marrow Transplantation - immunology | Adult | Female | Transplantation Conditioning - methods | Mycophenolic Acid - administration & dosage | Graft vs Host Disease - etiology | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Drug Administration Schedule | Graft Survival | Postoperative Complications - epidemiology | Vidarabine - analogs & derivatives | Granulocyte Colony-Stimulating Factor - therapeutic use | Postoperative Care - methods | Blood Component Transfusion | Hematologic Neoplasms - surgery | Disease-Free Survival | Tacrolimus - therapeutic use | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Hemoglobinuria, Paroxysmal - surgery | Cyclophosphamide - pharmacology | Graft vs Host Disease - prevention & control | Aged | Vidarabine - administration & dosage | Histocompatibility | Antimitotic agents | Evaluation | Mortality | Bone marrow | Dosage and administration | Transplantation | Antineoplastic agents | T cells | Cancer | Index Medicus
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2015, Volume 33, Issue 35, pp. 4167 - 4175
Journal Article