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Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2018, Volume 62, Issue 11
FK506 (tacrolimus) is an FDA-approved immunosuppressant indicated for the prevention of allograft rejections in patients undergoing organ transplants. In... 
Calcium signaling | Human fungal pathogen | Immunosuppressant | Calcineurin | FKBP12 | IMMUNOSUPPRESSANT FK506 | RAPAMYCIN | ASPERGILLUS-FUMIGATUS | human fungal pathogen | calcium signaling | MICROBIOLOGY | immunosuppressant | IMMUNOPHILIN | calcineurin | CALCINEURIN INHIBITORS | VIRULENCE | PHARMACOLOGY & PHARMACY | CRYPTOCOCCUS-NEOFORMANS | ALBICANS | TACROLIMUS | FLUCONAZOLE
Journal Article
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2019, Volume 17, Issue 36, pp. 8348 - 8353
Rapamycin-induced dimerization of FKBP and FRB has been utilized as a tool for co-localizing two proteins of interest in numerous applications. Due to the... 
Proteins | Analogs | Organic chemistry | Cycle protein | Complex formation | Tacrolimus-binding protein | Rapamycin | Dimerization | Biological activity
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2008, Volume 105, Issue 1, pp. 33 - 38
Journal Article
ACS MEDICINAL CHEMISTRY LETTERS, ISSN 1948-5875, 09/2019, Volume 10, Issue 9, pp. 1279 - 1283
FKBP12 ligands such as FK506 have been shown to activate the BMP signaling pathway and facilitate tissue regeneration, However, the immunosuppressive activity... 
nonimmunosuppressive | CHEMISTRY, MEDICINAL | regenerative medicine | SMAD1/5 | BMP signaling | FKBP ligands | calcineurin | CYCLOSPORINE-A | ARYL | TGF-BETA RECEPTOR | TACROLIMUS | INHIBITOR | DERIVATIVES | OLEFIN | FKVP
Journal Article
Herz, ISSN 0340-9937, 3/2004, Volume 29, Issue 2, pp. 162 - 166
Journal Article
Journal of Crohn's and Colitis, ISSN 1873-9946, 1/2016, Volume 10, Issue 1, pp. 31 - 37
Journal Article
RSC Advances, ISSN 2046-2069, 2015, Volume 5, Issue 9, pp. 6823 - 6828
FK506 exhibits neuroprotective and neuroregenerative activities in addition to its clinically important immunosuppressant properties. The macrolide ring of... 
IMMUNOSUPPRESSANTS FK506 | FK520 | FKBP | BIOSYNTHESIS | FK-506 | TACROLIMUS | CHEMISTRY, MULTIDISCIPLINARY | FAMILY | Pathways | Peptides | Natural products | Analogue | Genetic engineering | Oxidation | Biological activity
Journal Article