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1. Full Text Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms
by Debrand, Emmanuel and El Jai, Yasmine and Spence, Lorraine and Bate, Neil and Praekelt, Uta and Pritchard, Catrin A and Monkley, Susan J and Critchley, David R
The FEBS journal, ISSN 1742-464X, 03/2009, Volume 276, Issue 6, pp. 1610 - 1628
spermatogenesis | talin 2 isoforms | integrins | talin 2 | cytoskeleton | Cytoskeleton | Talin 2 | Spermatogenesis | Talin 2 isoforms | Integrins | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Promoter Regions, Genetic | Spermatids - metabolism | Alternative Splicing | Talin - chemistry | Exons | Humans | RNA, Messenger - genetics | Molecular Sequence Data | Male | Reverse Transcriptase Polymerase Chain Reaction | Talin - metabolism | Sequence Homology, Nucleic Acid | Gene Knockdown Techniques | Sequence Homology, Amino Acid | Kidney - metabolism | Animals | Talin - genetics | Base Sequence | DNA | CpG Islands | Mice | Talin - physiology | Proteins | Genetics | Biochemistry | Rodents | Cell adhesion & migration | Index Medicus | talin 2 | talin 2 isoforms | Original
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2. Full Text Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem
by Gingras, Alexandre R and Lagarrigue, Frederic and Cuevas, Monica N and Valadez, Andrew J and Zorovich, Marcus and McLaughlin, Wilma and Lopez-Ramirez, Miguel Alejandro and Seban, Nicolas and Ley, Klaus and Kiosses, William B and Ginsberg, Mark H
The Journal of cell biology, ISSN 0021-9525, 06/2019, Volume 218, Issue 6, pp. 1799 - 1809
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cricetinae | Cricetulus | Talin - chemistry | Humans | Lipids - physiology | Talin - metabolism | Integrins - metabolism | Telomere-Binding Proteins - genetics | Animals | Talin - genetics | Protein Binding | Protein Domains | Protein Conformation | Mutation | Telomere-Binding Proteins - metabolism | Binding Sites | CHO Cells | Rap1 protein | Charge reversal | Lipids | Talin | Activation | Platelets | Binding sites | Index Medicus
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3. Full Text Talins and kindlins: Partners in integrin-mediated adhesion
by Calderwood, David A and Campbell, Iain D and Critchley, David R
Nature reviews. Molecular cell biology, ISSN 1471-0072, 08/2013, Volume 14, Issue 8, pp. 503 - 517
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Integrins - physiology | Cell Adhesion - genetics | Multigene Family - physiology | Membrane Proteins - genetics | Humans | Neoplasm Proteins - physiology | Cell Communication - physiology | Cell Communication - genetics | Neoplasm Proteins - metabolism | Talin - metabolism | Integrins - metabolism | Animals | Talin - genetics | Membrane Proteins - physiology | Models, Biological | Membrane Proteins - metabolism | Talin - physiology | Neoplasm Proteins - genetics | Protein Binding - physiology | Physiological aspects | Research | Cell adhesion | Integrins | Protein binding | Index Medicus
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4. Full Text Talin - The master of integrin adhesions
by Klapholz, Benjamin and Brown, Nicholas H
Journal of cell science, ISSN 0021-9533, 08/2017, Volume 130, Issue 15, pp. 2435 - 2446
Talin | Mechanotransduction | Integrin | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Talin - genetics | Cell Adhesion - physiology | Drosophila | Humans | Integrins - genetics | Drosophila Proteins - genetics | Drosophila Proteins - metabolism | Mechanotransduction, Cellular - physiology | Talin - metabolism | Integrins - metabolism | Cell culture | Glycoproteins | Rigidity | Adhesion | Mammalian cells | Recruitment | Proteins | Adhesive strength | Actin | Fruit flies | Cytoskeleton | Extracellular matrix | Mechanical stimuli | Integrins | Index Medicus
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5. Full Text Talin1 phosphorylation activates β1 integrins: A novel mechanism to promote prostate cancer bone metastasis
by Jin, J.-K and Tien, P.-C and Cheng, C.-J and Song, J.H and Huang, C and Lin, S.-H and Gallick, G.E
Oncogene, ISSN 0950-9232, 05/2014, Volume 34, Issue 14, pp. 1811 - 1821
Phosphorylation | Humans | Bone Neoplasms - secondary | Male | Prostate - pathology | Talin - genetics | RNA Interference | Prostatic Neoplasms - pathology | Anoikis - genetics | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - biosynthesis | Lymphatic Metastasis | Talin - metabolism | Cell Adhesion | Cyclin-Dependent Kinase 5 - metabolism | Talin - biosynthesis | Integrin beta1 - metabolism | Animals | Focal Adhesions - metabolism | Cell Line, Tumor | Protein Binding | Adaptor Proteins, Signal Transducing - biosynthesis | Mice | RNA, Small Interfering | Enzyme Activation | Adaptor Proteins, Signal Transducing - metabolism | Cell Movement | Adaptor proteins | Tumor cells | Talin | Bone tumors | Metastasis | Kinases | Cyclin-dependent kinase 5 | Lymph nodes | Mimicry | Metastases | Mutants | Bone cancer | Cell activation | Cytoskeleton | Anoikis | Prostate cancer | Integrins | Index Medicus | prostate cancer | Cdk5 | talin | integrin | metastasis
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6. Full Text Vinculin controls talin engagement with the actomyosin machinery
by Atherton, Paul and Stutchbury, Ben and Wang, De-Yao and Jethwa, Devina and Tsang, Ricky and Meiler-Rodriguez, Eugenia and Wang, Pengbo and Bate, Neil and Zent, Roy and Barsukov, Igor L and Goult, Benjamin T and Critchley, David R and Ballestrem, Christoph
Nature communications, ISSN 2041-1723, 12/2015, Volume 6, Issue 1, pp. 10038 - 10038
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Structure, Tertiary | Cell Polarity | NIH 3T3 Cells | Actin Cytoskeleton - metabolism | Talin - chemistry | Vinculin - metabolism | Actin Cytoskeleton - chemistry | Talin - metabolism | Actomyosin - metabolism | Actins - genetics | Actomyosin - genetics | Vinculin - chemistry | Focal Adhesions - genetics | Animals | Talin - genetics | Vinculin - genetics | Focal Adhesions - metabolism | Protein Binding | Mice | Actin Cytoskeleton - genetics | Focal Adhesions - chemistry | Index Medicus
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7. Full Text Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation
by Zhu, Liang and Yang, Jun and Bromberger, Thomas and Holly, Ashley and Lu, Fan and Liu, Huan and Sun, Kevin and Klapproth, Sarah and Hirbawi, Jamila and Byzova, Tatiana V and Plow, Edward F and Moser, Markus and Qin, Jun
Nature communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1744 - 12
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | rap GTP-Binding Proteins - chemistry | Talin - chemistry | Humans | Models, Molecular | Recombinant Proteins - chemistry | Guanosine Triphosphate - metabolism | Recombinant Proteins - genetics | Talin - metabolism | Integrins - metabolism | Animals | Talin - genetics | Cell Adhesion - physiology | Nuclear Magnetic Resonance, Biomolecular | Protein Binding | Cell Membrane - metabolism | Mice | Protein Interaction Domains and Motifs | rap GTP-Binding Proteins - metabolism | Binding | Membranes | Talin | Homology | Guanosine triphosphatases | Adhesion | Cell spreading | Cell adhesion & migration | Rap1 protein | Cell activation | Adhesive strength | Cell adhesion | Microenvironments | Disruption | Protein interaction | Cell migration | Index Medicus
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8. Full Text The mechanical response of talin
by Yao, Mingxi and Goult, Benjamin T and Klapholz, Benjamin and Hu, Xian and Toseland, Christopher P and Guo, Yingjian and Cong, Peiwen and Sheetz, Michael P and Yan, Jie
Nature communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, pp. 11966 - 11966
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Talin - chemistry | Stress, Mechanical | Recombinant Fusion Proteins - metabolism | Thermodynamics | Endopeptidases - chemistry | Glutathione Transferase - genetics | Talin - genetics | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Gene Expression | Protein Structure, Secondary | Protein Refolding | Glutathione Transferase - metabolism | Models, Molecular | Recombinant Fusion Proteins - chemistry | Single Molecule Imaging - methods | Talin - metabolism | Protein Folding | Biomechanical Phenomena | Animals | Escherichia coli - genetics | Protein Binding | Recombinant Fusion Proteins - genetics | Mice | Kinetics | Index Medicus
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