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Journal Article
Nature, ISSN 0028-0836, 11/2012, Volume 491, Issue 7425, pp. 554 - 559
Regulatory T (T-reg) cells, characterized by expression of the transcription factor forkhead box P3 (Foxp3), maintain immune homeostasis by suppressing... 
FOXP3 EXPRESSION | TARGET GENES | PROFILES | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | AKT | MECHANISMS | DIFFERENTIATION | INDUCTION | FOXO1 | TOOL
Journal Article
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, ISSN 1015-8987, 2019, Volume 52, Issue 2, pp. 254 - 262
miR221 might have an important role in human embryo development. However, little is known about the function of miR221 in the human embryo. The aim of this... 
Target genes | Placenta | miR221 | DDIT4
Journal Article
Immunological Reviews, ISSN 0105-2896, 04/2006, Volume 210, Issue 1, pp. 171 - 186
Over the past few years, the transcription factor nuclear factor (NF)‐κB and the proteins that regulate it have emerged as a signaling system of pre‐eminent... 
TRANSCRIPTION FACTORS | TARGET GENES | ACTIVATION | TEMPORAL CONTROL | GENE-EXPRESSION | C-REL | IKK-ALPHA | TNF-ALPHA | IMMUNOLOGY | BINDING-SITES | BETA
Journal Article
Hormone and Metabolic Research, ISSN 0018-5043, 01/2018, Volume 50, Issue 3, pp. 179 - 192
Abstract Pituitary adenomas account for the top three primary intracranial tumors in terms of total incidence rates. The clinical symptoms presented by the... 
Review | miRNA | pituitary adenoma | pituitary gland | target genes
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 2011, Volume 36, Issue 1, pp. 30 - 38
Reactive oxygen species (ROS) are small and highly reactive molecules that can oxidize proteins, lipids and DNA. When tightly controlled, ROS serve as... 
CANCER-CELLS | APOPTOSIS | MITOCHONDRIAL PERMEABILITY TRANSITION | OXIDATIVE STRESS | TRANSCRIPTION FACTOR NRF2 | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEGRADATION | MUTANT SOD1 | TARGET GENE | CELL-DEATH | Animals | Reactive Oxygen Species - metabolism | Signal Transduction | Antioxidants - metabolism | Humans | Mitochondria - metabolism | Autophagy
Journal Article
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 11/2018, Volume 18, Issue 11, pp. 696 - 705
The Catalogue of Somatic Mutations in Cancer (COSMIC) Cancer Gene Census (CGC) is an expert-curated description of the genes driving human cancer that is used... 
FOXA1 | TARGET GENES | INHIBITION | ONCOLOGY | ONCOGENIC ROLE | PROLIFERATION | MUTATIONS | CELL-CYCLE PROGRESSION | TRANSCRIPTIONAL REGULATION | EXPRESSION | BREAST | Neoplasms - therapy | Neoplasms - genetics | Mutation - genetics | Neoplasms - pathology | Humans | Censuses | Proteins | Medical research | Census | Genes | Genetics | Mutation | Cancer | Tumors
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 11/2016, Volume 17, Issue 11, pp. 722 - 735
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2011, Volume 286, Issue 20, pp. 17672 - 17681
DDR1 (discoidin domain receptor tyrosine kinase 1) kinase s highly expressed in a variety of human cancers and occasionally mutated in lung cancer and... 
APOPTOSIS | CELLS | OVEREXPRESSION | DISCOIDIN DOMAIN RECEPTOR-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | TARGET GENE | EXPRESSION | SOMATIC MUTATIONS | HUMAN HOMOLOG | P53
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2009, Volume 284, Issue 25, pp. 16767 - 16775
Hypoxia-inducible factor (HIF) controls an extensive range of adaptive responses to hypoxia. To better understand this transcriptional cascade we performed... 
STEM-CELLS | CELLULAR ADAPTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | C-MYC | PROMOTER REGION | FACTOR-I | HIF-1-ALPHA | TARGET GENE | UP-REGULATION | CANCER | Transcription, Chromatin, and Epigenetics
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2013, Volume 49, Issue 5, pp. 825 - 837
Journal Article