Journal of Controlled Release, ISSN 0168-3659, 11/2013, Volume 172, Issue 1, pp. 207 - 218
Recently, chitosan has attracted significant attention in the formulation of small interfering RNA (siRNA). Because of its cationic nature, chitosan can easily...
Nanoparticles | siRNA | Delivery barriers | RNA interference | Chitosan | Ligand | THERAPEUTICS | TARGETED DRUG-DELIVERY | TRANSFECTION | POLYETHYLENIMINE | CHEMISTRY, MULTIDISCIPLINARY | CARRIER | IN-VITRO | THERAPY | DNA | PHARMACOLOGY & PHARMACY | MOLECULAR-WEIGHT CHITOSAN | Gene Transfer Techniques | RNA, Small Interfering - genetics | Animals | Chitosan - chemistry | RNA Interference | RNA, Small Interfering - therapeutic use | Humans | Models, Molecular | RNA, Small Interfering - administration & dosage | Chitosan - metabolism | Drugs | Drug delivery systems | RNA | Vehicles
Nanoparticles | siRNA | Delivery barriers | RNA interference | Chitosan | Ligand | THERAPEUTICS | TARGETED DRUG-DELIVERY | TRANSFECTION | POLYETHYLENIMINE | CHEMISTRY, MULTIDISCIPLINARY | CARRIER | IN-VITRO | THERAPY | DNA | PHARMACOLOGY & PHARMACY | MOLECULAR-WEIGHT CHITOSAN | Gene Transfer Techniques | RNA, Small Interfering - genetics | Animals | Chitosan - chemistry | RNA Interference | RNA, Small Interfering - therapeutic use | Humans | Models, Molecular | RNA, Small Interfering - administration & dosage | Chitosan - metabolism | Drugs | Drug delivery systems | RNA | Vehicles
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 09/2008, Volume 97, Issue 9, pp. 3518 - 3590
This article provides an overview of principles and barriers relevant to intracellular drug and gene transport, accumulation and retention (collectively called...
gene delivery | controlled release/delivery | in silico modeling | polymeric drug carrier | liposomes | polymeric drug delivery | pharmacokinetics/pharmacodynamics | nanoparticle | targeted drug delivery | cancer | distribution | nanovehicle | Gene delivery | Controlled release/delivery | Targeted drug delivery | Nanoparticle | Distribution | Nanovehicle | Liposomes | Polymeric drug delivery | Polymeric drug carrier | Pharmacokinetics/pharmacodynamics | Cancer | In silico modeling | COLONY-STIMULATING FACTOR | CAVEOLAE-MEDIATED ENDOCYTOSIS | FUNCTIONALIZED CARBON NANOTUBES | TUMOR-INDUCED ANGIOGENESIS | SOLID LIPID NANOPARTICLES | PHARMACOLOGY & PHARMACY | IRON-OXIDE NANOPARTICLES | CHEMISTRY, MEDICINAL | CHEMISTRY, MULTIDISCIPLINARY | BREAST-CANCER CELLS | PH-SENSITIVE LIPOSOMES | SEMICONDUCTOR QUANTUM DOTS | ACCELERATED BLOOD CLEARANCE | Ligands | Signal Transduction | Static Electricity | Nanotechnology | Drug Delivery Systems | delivery | pharmacodynamics | controlled release | pharmacokinetics
gene delivery | controlled release/delivery | in silico modeling | polymeric drug carrier | liposomes | polymeric drug delivery | pharmacokinetics/pharmacodynamics | nanoparticle | targeted drug delivery | cancer | distribution | nanovehicle | Gene delivery | Controlled release/delivery | Targeted drug delivery | Nanoparticle | Distribution | Nanovehicle | Liposomes | Polymeric drug delivery | Polymeric drug carrier | Pharmacokinetics/pharmacodynamics | Cancer | In silico modeling | COLONY-STIMULATING FACTOR | CAVEOLAE-MEDIATED ENDOCYTOSIS | FUNCTIONALIZED CARBON NANOTUBES | TUMOR-INDUCED ANGIOGENESIS | SOLID LIPID NANOPARTICLES | PHARMACOLOGY & PHARMACY | IRON-OXIDE NANOPARTICLES | CHEMISTRY, MEDICINAL | CHEMISTRY, MULTIDISCIPLINARY | BREAST-CANCER CELLS | PH-SENSITIVE LIPOSOMES | SEMICONDUCTOR QUANTUM DOTS | ACCELERATED BLOOD CLEARANCE | Ligands | Signal Transduction | Static Electricity | Nanotechnology | Drug Delivery Systems | delivery | pharmacodynamics | controlled release | pharmacokinetics
Journal Article
Annual Review of Chemical and Biomolecular Engineering, ISSN 1947-5438, 07/2010, Volume 1, Issue 1, pp. 149 - 173
Polymers have played an integral role in the advancement of drug delivery technology by providing controlled release of therapeutic agents in constant doses...
recognitive polymers | controlled release | intracellular delivery | polymer therapeutics | stimuli-responsive | responsive polymers | GENE DELIVERY | PH-SENSITIVE SYSTEM | POLY(BETA-AMINO ESTER) NANOPARTICLES | SIRNA DELIVERY | ENGINEERING, CHEMICAL | IN-VITRO | TUMOR-TARGETED DELIVERY | MEMBRANE-DISRUPTIVE ACTIVITY | RESPONSIVE PSEUDO-PEPTIDES | CHEMISTRY, APPLIED | HPMA COPOLYMER | SOFT CONTACT-LENSES | Delayed-Action Preparations - chemistry | Polymers - chemistry | Animals | Pharmaceutical Preparations - administration & dosage | Humans | Proteins - administration & dosage | Drugs | Composition | Controlled release preparations | Chemical properties | Controlled release technology | Research | Polymers | Health aspects | Controlled release
recognitive polymers | controlled release | intracellular delivery | polymer therapeutics | stimuli-responsive | responsive polymers | GENE DELIVERY | PH-SENSITIVE SYSTEM | POLY(BETA-AMINO ESTER) NANOPARTICLES | SIRNA DELIVERY | ENGINEERING, CHEMICAL | IN-VITRO | TUMOR-TARGETED DELIVERY | MEMBRANE-DISRUPTIVE ACTIVITY | RESPONSIVE PSEUDO-PEPTIDES | CHEMISTRY, APPLIED | HPMA COPOLYMER | SOFT CONTACT-LENSES | Delayed-Action Preparations - chemistry | Polymers - chemistry | Animals | Pharmaceutical Preparations - administration & dosage | Humans | Proteins - administration & dosage | Drugs | Composition | Controlled release preparations | Chemical properties | Controlled release technology | Research | Polymers | Health aspects | Controlled release
Journal Article
Theranostics, ISSN 1838-7640, 2016, Volume 6, Issue 9, pp. 1306 - 1323
With the unprecedented progresses of biomedical nanotechnology during the past few decades, conventional drug delivery systems (DDSs) have been involved into...
Smart nanoplatform | Drug delivery system (DDS) | Nanomedicine | Controlled release | Biomaterials | THERMOSENSITIVE POLYMERIC MICELLES | IRON-OXIDE NANOPARTICLES | GOLD NANOPARTICLES | MEDICINE, RESEARCH & EXPERIMENTAL | DOXORUBICIN DELIVERY | MESOPOROUS SILICA NANOPARTICLES | TEMPERATURE-SENSITIVE LIPOSOMES | MAGNETIC NANOPARTICLES | STIMULI-RESPONSIVE NANOCARRIERS | BIOMEDICAL APPLICATIONS | RATIONAL DESIGN | Animals | Theranostic Nanomedicine - methods | Humans | Drug Discovery - trends | Drug Discovery - methods | Nanoparticles - administration & dosage | Molecular Targeted Therapy - methods | Drug Delivery Systems
Smart nanoplatform | Drug delivery system (DDS) | Nanomedicine | Controlled release | Biomaterials | THERMOSENSITIVE POLYMERIC MICELLES | IRON-OXIDE NANOPARTICLES | GOLD NANOPARTICLES | MEDICINE, RESEARCH & EXPERIMENTAL | DOXORUBICIN DELIVERY | MESOPOROUS SILICA NANOPARTICLES | TEMPERATURE-SENSITIVE LIPOSOMES | MAGNETIC NANOPARTICLES | STIMULI-RESPONSIVE NANOCARRIERS | BIOMEDICAL APPLICATIONS | RATIONAL DESIGN | Animals | Theranostic Nanomedicine - methods | Humans | Drug Discovery - trends | Drug Discovery - methods | Nanoparticles - administration & dosage | Molecular Targeted Therapy - methods | Drug Delivery Systems
Journal Article
Biotechnology Advances, ISSN 0734-9750, 09/2013, Volume 31, Issue 5, pp. 593 - 606
The application of nanotechnology in medicine, known as nanomedicine, has introduced a plethora of nanoparticles of variable chemistry and design...
Physiochemical properties | Therapeutic mechanism | Nanoparticles toxicity | Biological barrier | Nanomedicine | Targeted drug delivery system | Gold nanomaterials | THERAPEUTIC NANOPARTICLES | PRO-DRUG | OPTICAL-PROPERTIES | CELL-SURFACE | BLOOD-BRAIN-BARRIER | CARBON NANOTUBES | TRIGGERED RELEASE | TRANSFERRIN RECEPTOR | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GROWTH-FACTOR | Gold - chemistry | Cell Line | Gold - administration & dosage | Animals | Metal Nanoparticles - administration & dosage | Humans | Metal Nanoparticles - chemistry | Nanomedicine - methods | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - chemistry | Drug Delivery Systems - methods | Drugs | Nanoparticles | Drug delivery systems | Nanotechnology | Vehicles | Index Medicus
Physiochemical properties | Therapeutic mechanism | Nanoparticles toxicity | Biological barrier | Nanomedicine | Targeted drug delivery system | Gold nanomaterials | THERAPEUTIC NANOPARTICLES | PRO-DRUG | OPTICAL-PROPERTIES | CELL-SURFACE | BLOOD-BRAIN-BARRIER | CARBON NANOTUBES | TRIGGERED RELEASE | TRANSFERRIN RECEPTOR | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GROWTH-FACTOR | Gold - chemistry | Cell Line | Gold - administration & dosage | Animals | Metal Nanoparticles - administration & dosage | Humans | Metal Nanoparticles - chemistry | Nanomedicine - methods | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - chemistry | Drug Delivery Systems - methods | Drugs | Nanoparticles | Drug delivery systems | Nanotechnology | Vehicles | Index Medicus
Journal Article