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BBA - General Subjects, ISSN 0304-4165, 07/2015, Volume 1850, Issue 7, pp. 1375 - 1388
Amphipathic sweet and bitter tastants inhibit purified forms of the protein kinases GRK2, GRK5 and PKA activities. Here we tested whether membrane-permeable... 
Signaling | Membrane-permeable | GRK2 | Desensitization | Tastants | β2AR
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, ISSN 0304-4165, 07/2015, Volume 1850, Issue 7, pp. 1375 - 1388
Background: Amphipathic sweet and bitter tastants inhibit purified forms of the protein kinases GRK2, GRK5 and PKA activities. Here we tested whether... 
betaAR | CELLS | Desensitization | PHOSPHORYLATION | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSDUCTION | BETA-ARRESTIN | DIHYDROCHALCONE | Signaling | CYCLIC-AMP | GRK2 | BIOPHYSICS | Tastants | Membrane-permeable | BITTER-TASTE RECEPTORS | BETA-ADRENERGIC RECEPTOR | SWEET TASTANTS
Journal Article
INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE, ISSN 1555-0265, 07/2019, Volume 14, Issue 6, pp. 727 - 732
Purpose: The authors investigated the potential benefit of ingesting 2 mM of quinine (bitter tastant) on a 3000-m cycling time-trial (TT) performance. Methods:... 
SPORT SCIENCES | PHYSIOLOGY | sprint | tastants | exercise | POWER | TEAM | RUN | sport | power output
Journal Article
Nature, ISSN 0028-0836, 06/2018, Volume 558, Issue 7708, pp. 127 - 131M
The ability of the taste system to identify a tastant (what it tastes like) enables animals to recognize and discriminate between the different basic taste... 
Brain | Taste discrimination | Cortex (gustatory) | Neurosciences | Amygdala | Neurons | Bitter taste | Gene expression | Substrates | Proteins | Organic chemistry | Coding | Tastants | Sweet taste | Taste | Mice
Journal Article
Nutritional Neuroscience, ISSN 1028-415X, 04/2018, pp. 1 - 13
Intragastric bitter tastants may decrease appetite and food intake. We aimed to investigate the gut-brain signaling and brain mechanisms underlying these... 
Appetite | Bitter tastants | Pharmacological MRI | Food intake | Ghrelin | Motilin | Brain-gut axis | Quinine
Journal Article
Journal of Animal Science, ISSN 0021-8812, 12/2018, Volume 96, pp. 352 - 352
As we age our sensory perception alters partly as a result of normal ageing but also due to coexisting medical conditions. Threshold changes become... 
Parkinson's disease | Neurodegenerative diseases | Thresholds | Umami | Effects | Management | Sensory perception | Metabolism | Zinc | Taste thresholds | Tastants | Aging | Dementia disorders | Perception | Taste | Aging (natural) | Selenium | Odor | Movement disorders | Thyroid
Journal Article
Biochimica et Biophysica Acta - General Subjects, ISSN 0304-4165, 07/2015, Volume 1850, Issue 7, pp. 1375 - 1388
Background Amphipathic sweet and bitter tastants inhibit purified forms of the protein kinases GRK2, GRK5 and PKA activities. Here we tested whether... 
Signaling | Membrane-permeable | Desensitization | GRK2 | Tastants | β 2 AR
Journal Article
Sensors & Actuators: B. Chemical, ISSN 0925-4005, 03/2014, Volume 192, pp. 361 - 368
Journal Article
The Journal of Neuroscience, ISSN 0270-6474, 09/2018, Volume 38, Issue 39, p. 8463
In substance use disorders, negative affect associated with drug withdrawal can elicit strong drug craving and promote relapse. One brain region implicated in... 
Drug addiction | Brain | Lithium chloride | Bitter taste | Taste aversion | Lithium | Quinine | Emotions | Substance use | Drug self-administration | Signaling | Saccharin | Reactivity | Motivation | Tastants | Reinforcement | Cortex (insular) | Sweet taste | Taste | Cocaine | Lithium chlorides | Conditioning
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 03/2018, Volume 66, Issue 10, pp. 2295 - 2300
Humans perceive bitterness via around 25 different bitter receptors. Therefore, the identification of antagonists remains a complex challenge. We previously... 
bitter modulators | HGT-1 cells | bitter masking | TAS2Rs | bitter tastants | WINE | FOOD SCIENCE & TECHNOLOGY | ACID-SECRETION | MECHANISMS | CHEMOSENSORY CELLS | IDENTIFICATION | bitter masking TAS2Rs | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED | TASTE RECEPTORS | EXPRESSION
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 11027 - 10
Previous attempts to uncover a relation between taste processing and weight status have yielded inconclusive results leaving it unclear whether lean and obese... 
ACTIVATION | EEG | MULTIDISCIPLINARY SCIENCES | OVERWEIGHT | SENSITIVITY | ADULTS | DYNAMICS | FOOD CUES | POTENTIALS | GUSTATORY PERCEPTION | INDEPENDENT COMPONENT ANALYSIS | Obesity | Taste stimuli | Gustatory evoked potentials | Sensory evaluation | Tastants | Information processing | Reinforcement | Sweet taste | Taste | Latency
Journal Article
Neuron, ISSN 0896-6273, 01/2018, Volume 97, Issue 1, pp. 67 - 74.e4
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 3549 - 8
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e101578 - e101578
Bitter tastants can induce relaxation in precontracted airway smooth muscle by activating big-conductance potassium channels (BKs) or by inactivating... 
CELLS | ACTIVATION | PORTAL-VEIN MYOCYTES | BK CHANNELS | MULTIDISCIPLINARY SCIENCES | TASTANT-INDUCED BRONCHODILATION | CALCIUM | SIGNALS | CURRENTS | RECEPTORS | EXPRESSION | Nifedipine - pharmacology | Acetylcholine - pharmacology | Calcium - metabolism | Cells, Cultured | Male | Muscle, Smooth - metabolism | TRPC Cation Channels - antagonists & inhibitors | Potassium Channels - metabolism | Chloroquine - pharmacology | Patch-Clamp Techniques | Animals | Ion Channels - metabolism | Muscle Contraction - drug effects | TRPC Cation Channels - metabolism | Mice | Mice, Inbred BALB C | Antirheumatic Agents - pharmacology | Calcium Channels, L-Type - metabolism | Muscle Relaxation - drug effects | Muscle, Smooth - cytology | Action Potentials - drug effects | Pyrazoles - pharmacology | Bank clearinghouses | Smooth muscle | Nifedipine | Chloroquine | Potassium conductance | Biology | Kinases | Contraction | Channels | Pyrazole | Proteins | Respiratory tract | Transient receptor potential proteins | Elevation | Restoration | Rodents | Life sciences | Potassium channels (voltage-gated) | Inhibition | Cardiology | Calcium channels | Calcium (intracellular) | Calcium channels (voltage-gated) | Bitter taste | Muscles | Biophysics | Potassium channels | Gene expression | Epithelium | Muscle contraction | Resistance | Tastants | Calcium channels (L-type) | Acetylcholine | Conductance | Cations | Laboratory animals | Potassium | Calcium ions | Index Medicus
Journal Article
Food Quality and Preference, ISSN 0950-3293, 03/2016, Volume 48, pp. 70 - 80
The effect of cross-modal sensory interactions between cheese aroma and cheese taste on both cheese flavour intensity and cheese flavour character were... 
Cheese flavour intensity | Interactions | Cheese flavour character | Aroma-taste | Cross-modal | SYSTEM | TASTANTS | ODORS | FOOD SCIENCE & TECHNOLOGY | MODEL | CONGRUENCY | BEVERAGE | BASIC TASTES | ENHANCEMENT | CHEDDAR CHEESE | FOOD | Cheese
Journal Article