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American Journal of Pathology, The, ISSN 0002-9440, 2013, Volume 183, Issue 5, pp. 1498 - 1507
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 24, pp. 6543 - 6552
Abstract Angiogenesis, the formation of new blood vessels, plays a pivotal role in tumor progression and for this reason angiogenesis inhibitors are an... 
Advanced Basic Science | Dentistry | Heparin conjugate | Angiogenesis inhibitor | Oral delivery | Deoxycholic acid | BILE-ACID | CATIONIC ANALOG | MICROCOMPUTED TOMOGRAPHY | MATERIALS SCIENCE, BIOMATERIALS | TRANSPORTERS | ENGINEERING, BIOMEDICAL | CARRIER | DISCOVERY | THERAPY | MOLECULAR-WEIGHT HEPARIN | RESISTANCE | ABSORPTION | Intestines - drug effects | Neovascularization, Physiologic - drug effects | Heparin, Low-Molecular-Weight - analogs & derivatives | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Deoxycholic Acid - chemistry | Intestinal Absorption - drug effects | Biological Availability | Male | Antineoplastic Agents - therapeutic use | Spheroids, Cellular - cytology | Angiogenesis Inhibitors - blood | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | Taurocholic Acid - chemistry | Intestines - physiology | Taurocholic Acid - analogs & derivatives | Heparin - pharmacology | Heparin, Low-Molecular-Weight - chemical synthesis | Caco-2 Cells | Human Umbilical Vein Endothelial Cells - drug effects | Oxidation-Reduction | Administration, Oral | Taurocholic Acid - chemical synthesis | Spheroids, Cellular - metabolism | Angiogenesis Inhibitors - pharmacology | Heparin, Low-Molecular-Weight - chemistry | Angiogenesis Inhibitors - pharmacokinetics | Antineoplastic Agents - chemistry | Rats, Sprague-Dawley | Animals | Deoxycholic Acid - pharmacology | Cell Proliferation - drug effects | Neoplasms - pathology | Heparin - chemistry | Angiogenesis Inhibitors - chemistry | Analysis | Drugstores | Neovascularization | Angiogenesis inhibitors | Vascular endothelial growth factor | Biomedical engineering | Index Medicus
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 7/2015, Volume 32, Issue 7, pp. 2318 - 2327
To overcome definite limitations of angiogenesis inhibitors such as insufficient therapeutic efficacy as a single drug and resisting or conflicting effect... 
Biochemistry, general | Biomedical Engineering | hypoxia | Biomedicine | Pharmacy | angiogenesis | cyclooxygenase-2 | Medical Law | combination therapy | heparin conjugate | Pharmacology/Toxicology | Angiogenesis | Hypoxia | Cyclooxygenase-2 | Combination therapy | Heparin conjugate | PATHWAYS | METASTASIS | MACROPHAGES | TUMOR ANGIOGENESIS | CELECOXIB | CHEMISTRY, MULTIDISCIPLINARY | CELL CARCINOMA | ANTIANGIOGENIC THERAPY | INFLAMMATION | PHARMACOLOGY & PHARMACY | CANCER PREVENTION | Human Umbilical Vein Endothelial Cells | Celecoxib - administration & dosage | Heparin, Low-Molecular-Weight - pharmacology | Heparin, Low-Molecular-Weight - analogs & derivatives | Humans | Male | Celecoxib - chemistry | Heparin, Low-Molecular-Weight - therapeutic use | Neovascularization, Pathologic - pathology | Cyclooxygenase 2 - biosynthesis | Dose-Response Relationship, Drug | Angiogenesis Inhibitors - administration & dosage | Cyclooxygenase 2 Inhibitors - therapeutic use | Angiogenesis Inhibitors - therapeutic use | Taurocholic Acid - chemistry | Drug Therapy, Combination | Taurocholic Acid - analogs & derivatives | Taurocholic Acid - pharmacology | Cell Hypoxia - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 Inhibitors - administration & dosage | Angiogenesis Inhibitors - pharmacology | Heparin, Low-Molecular-Weight - chemistry | Celecoxib - pharmacology | Celecoxib - therapeutic use | Mice, Inbred Strains | Xenograft Model Antitumor Assays | Animals | Taurocholic Acid - administration & dosage | Neovascularization, Pathologic - drug therapy | Taurocholic Acid - therapeutic use | Neovascularization, Pathologic - metabolism | Heparin, Low-Molecular-Weight - administration & dosage | Angiogenesis Inhibitors - chemistry | Drugstores | COX-2 inhibitors | Neovascularization | Angiogenesis inhibitors | Deoxycholic acid | Inhibitor drugs | Pharmaceutical sciences | Tumors
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 86, pp. 56 - 67
Abstract Targeting multiple stages in metastatic breast cancer is one of the effective ways to inhibit metastatic progression. To target human metastatic... 
Advanced Basic Science | Dentistry | Polymeric bile acid | TGF-β1 | Low molecular weight heparin | CXCL12 | Metastasis | Multi-stage targeting | MATERIALS SCIENCE, BIOMATERIALS | TGF-BETA | ANGIOGENESIS | TGF-beta 1 | ENGINEERING, BIOMEDICAL | DOCKING | TUMORS | DELIVERY | ROLES | BINDING | Heparin, Low-Molecular-Weight - pharmacology | Heparin, Low-Molecular-Weight - analogs & derivatives | Humans | Transforming Growth Factor beta1 - metabolism | Epithelial-Mesenchymal Transition - drug effects | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Breast - metabolism | Heparin, Low-Molecular-Weight - therapeutic use | Breast Neoplasms - metabolism | Neoplasm Metastasis - prevention & control | Female | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Breast - pathology | Taurocholic Acid - analogs & derivatives | Taurocholic Acid - pharmacology | Deoxycholic Acid - therapeutic use | Deoxycholic Acid - analogs & derivatives | Antineoplastic Agents - chemistry | Mice, SCID | Breast Neoplasms - drug therapy | Cell Movement - drug effects | Animals | Chemokine CXCL12 - metabolism | Deoxycholic Acid - pharmacology | Breast - drug effects | Breast Neoplasms - pathology | Neoplasm Metastasis - pathology | Taurocholic Acid - therapeutic use | Cell Line, Tumor | Prevention | Analysis | Development and progression | Bone morphogenetic proteins | Breast cancer | Transforming growth factors | Intermediate filament proteins | Patient compliance | Deoxycholic acid | Cancer | Index Medicus | Binding | Phosphorylation | Receptors | Computer simulation | Breast | In vitro testing | Inhibition
Journal Article
Hepatology, ISSN 0270-9139, 09/2017, Volume 66, Issue 3, pp. 869 - 884
Journal Article
Hepatology, ISSN 0270-9139, 12/2012, Volume 56, Issue 6, pp. 2387 - 2397
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2013, Volume 57, Issue 1, pp. 664 - 667
Journal Article
The Journal of surgical research, ISSN 0022-4804, 05/2015, Volume 195, Issue 2, pp. 390 - 395
Metabolites are underappreciated for their effect on coagulation. Taurocholic acid (TUCA), a bile acid, has been shown to regulate cellular activity and... 
Taurocholic Acid - pharmacology | Fibrinolysis - drug effects | Animals | Humans | Tranexamic Acid - pharmacology | Platelet Aggregation Inhibitors - pharmacology | Rats | Adult | Male | Rats, Sprague-Dawley | fibrinolysis | clot strength | platelet dysfunction | taurocholic acid | bile salt | thrombelastography
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 03/2007, Volume 292, Issue 3, pp. G718 - G724
Salivary nitrate from dietary or endogenous sources is reduced to nitrite by oral bacteria. In the acidic stomach, nitrite is further reduced to bioactive... 
Rats | Laser-Doppler flowmetry | Endothelial nitric oxide synthase deficient | chromium-labeled EDTA clearance | Gastric mucus | Nitrite | PHYSIOLOGY | INTRAGASTRIC NITRIC-OXIDE | ACID | RAT | PERMEABILITY | PROTECTION | BICARBONATE | laser-Doppler flowmetry | endothelial nitric oxide synthase deficient | gastric mucus | nitrite | IN-VIVO | LASER-DOPPLER | rats | GASTROENTEROLOGY & HEPATOLOGY | STOMACH | THICKNESS | Diclofenac - pharmacology | Nitrates - pharmacology | Nitrites - metabolism | Male | Mucus - drug effects | Stomach - metabolism | Nitrites - administration & dosage | Vascular Resistance - physiology | Regional Blood Flow - drug effects | Gastric Mucosa - drug effects | Vascular Resistance - drug effects | Mucus - metabolism | Blood Pressure - drug effects | Stomach - drug effects | Gastric Mucosa - blood supply | Taurocholic Acid - pharmacology | Permeability - drug effects | Administration, Oral | Mice, Inbred C57BL | Nitric Oxide Synthase Type III | Nitrites - pharmacology | Rats, Sprague-Dawley | Nitrates - administration & dosage | Mice, Knockout | Animals | Taurocholic Acid - administration & dosage | Nitric Oxide Synthase Type II - genetics | Gastric Mucosa - physiology | Mice | Mucus - chemistry | Diclofenac - administration & dosage | Nitric Oxide - metabolism | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICINE | Nitric Oxide/metabolism | Mice; Inbred C57BL | Nitric Oxide Synthase Type II/genetics | Gastric Mucosa/blood supply/drug effects/physiology | Diclofenac/administration & dosage/pharmacology | Regional Blood Flow/drug effects | Rats; Sprague-Dawley | Administration; Oral | Taurocholic Acid/administration & dosage/pharmacology | Mice; Knockout | Mucus/chemistry/drug effects/metabolism | Nitrites/administration & dosage/metabolism/pharmacology | Permeability/drug effects | Blood Pressure/drug effects | MEDICIN | Stomach/drug effects/metabolism | Vascular Resistance/drug effects/physiology | Nitrates/administration & dosage/pharmacology
Journal Article
34.