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Chemical Reviews, ISSN 0009-2665, 12/2011, Volume 111, Issue 12, pp. 7652 - 7709
Wang et al examine natural taxane developments that have occurred since 1828. The article focuses on paclitaxel. 
Taxane
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 12/2012, Volume 6, pp. 371 - 384
The taxanes (paclitaxel and docetaxel) represent an important class of antineoplastic agents that interfere with microtubule function leading to altered... 
Taxane analogs | New antimicrotubule agents | Taxane(s) | Novel taxanes | New taxane formulations | CHEMISTRY, MEDICINAL | GYNECOLOGIC-ONCOLOGY-GROUP | POLYMERIC MICELLAR PACLITAXEL | PRIMARY PERITONEAL CANCER | new antimicrotubule agents | ADVANCED PANCREATIC-CANCER | CELL LUNG-CANCER | PHASE-III TRIAL | taxane analogs | new taxane formulations | IXABEPILONE PLUS CAPECITABINE | taxane(s) | ALBUMIN-BOUND PACLITAXEL | METASTATIC BREAST-CANCER | PHARMACOLOGY & PHARMACY | novel taxanes | DOCOSAHEXAENOIC ACID-PACLITAXEL | United States | Humans | Paclitaxel - adverse effects | Antineoplastic Agents - therapeutic use | Drug Approval | Antineoplastic Agents - administration & dosage | Paclitaxel - therapeutic use | Neoplasms - drug therapy | Taxoids - administration & dosage | Taxoids - therapeutic use | Antineoplastic Agents, Phytogenic - administration & dosage | Antineoplastic Agents - adverse effects | Drug Design | Antineoplastic Agents, Phytogenic - therapeutic use | Neoplasms - pathology | Paclitaxel - administration & dosage | Taxoids - adverse effects | United States Food and Drug Administration | Antineoplastic Agents, Phytogenic - adverse effects | Antimitotic agents | Drugs | Care and treatment | Patient outcomes | Analysis | Product/Service Evaluations | Research | Antineoplastic agents | Cancer | Regulatory agencies | Toxicity | Mitosis | Lung cancer | Bladder | Yew | Taxane | Allergic reactions | Neuropathy | Drug resistance | Analogs | Paclitaxel | Needles | Myelosuppression | Gastric cancer | Taxotere | Formulations | Trees | Solvents | Squamous cell carcinoma | Sarcoma | Taxol | Hypersensitivity | Breast cancer | Pharmacology | FDA approval | Esophagus | Organic chemistry | Chemotherapy | Dilution | Side effects | Cell death | Reagents | Head and neck cancer | Solid tumors | Taxanes | Prostate cancer | Epothilones | Prostate
Journal Article
Revista Cubana de Farmacia, ISSN 0034-7515, 10/2017, Volume 50, Issue 4
Journal Article
Tetrahedron, ISSN 0040-4020, 07/2013, Volume 69, Issue 27-28, pp. 5685 - 5701
A full account of synthetic efforts toward a lowly oxidized taxane framework is presented. A non-natural taxane, dubbed 'taxadienone', was synthesized as our... 
Cyclase phase | Terpene | Taxadiene | Taxane | Total synthesis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2018, Volume 24, Issue 21, pp. 5261 - 5271
Purpose: Previous human epidermal growth factor receptor-2 (HER2)-derived resistance studies were based on ex vivo models, which could not mirror evolutionary... 
IMPACT | INHIBITION | MANAGEMENT | TRASTUZUMAB | EFFICACY | ONCOLOGY | TAXANE | TUMOR-CELLS | PACLITAXEL
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2019, Volume 58, Issue 35, pp. 12159 - 12163
1‐Hydroxytaxinine ( 1 ) is a cytotoxic taxane diterpenoid. Its central eight‐membered B‐ring possesses four oxygen‐functionalized centers (C1, C2, C9, and C10)... 
tellurium | natural products | terpenoids | total synthesis | radicals | FORMAL TOTAL-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | C-RING | STRATEGIES | TAXANE SYNTHESIS | TAXOL | DEOXYGENATION | CONSTRUCTION | CHEMISTRY | COMPLETION | ENANTIOSELECTIVE TOTAL-SYNTHESIS | Synthesis | Organic compounds | Tellurides | Stereoselectivity | Quaternary | Reagents | Titanium | Cytotoxicity | Taxane | Coupling
Journal Article
Annals of Oncology, ISSN 0923-7534, 05/2018, Volume 29, Issue 5, pp. 1195 - 1202
Abstract Background Capecitabine is an approved standard therapy for anthracycline- and taxane-pretreated locally advanced or metastatic breast cancer (BC).... 
Phase III | Metastatic breast cancer | Taxane resistant | Vinflunine | Capecitabine | Pretreated
Journal Article
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, ISSN 1055-9965, 6/2018, Volume 27, Issue 6, pp. 680 - 688
Journal Article
Supportive Care in Cancer, ISSN 0941-4355, 1/2018, Volume 26, Issue 1, pp. 203 - 211
Journal Article
Cancer, ISSN 0008-543X, 03/2017, Volume 123, Issue 5, pp. 759 - 768
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 3, pp. 658 - 665
Purpose: Severe skeletal muscle (SM) loss (sarcopenia) is associated with poor cancer outcomes, including reduced survival and increased toxicity. This study... 
CACHEXIA | METAANALYSIS | SOLID TUMORS | PHARMACOKINETICS | ONCOLOGY | STATISTICS | COLORECTAL-CANCER | DETERMINANT | BODY-MASS INDEX | SARCOPENIA | PACLITAXEL | Body Composition | Prognosis | Follow-Up Studies | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Hospitalization - statistics & numerical data | Tomography, X-Ray Computed | Sarcopenia - chemically induced | Antineoplastic Agents, Phytogenic - administration & dosage | Sarcopenia - etiology | Aged, 80 and over | Adult | Female | Body Surface Area | Taxoids - adverse effects | Antineoplastic Agents, Phytogenic - adverse effects | Body Mass Index | Kaplan-Meier Estimate | Proportional Hazards Models | Sarcopenia - diagnostic imaging | Organ Size | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Adenocarcinoma - complications | Adenocarcinoma - secondary | Breast Neoplasms - complications | Taxoids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Muscle, Skeletal - diagnostic imaging | Breast Neoplasms - mortality | Aged | Muscle, Skeletal - pathology | Specific Gravity | Adenocarcinoma - mortality | Vertebrae | Toxicity | Test procedures | Muscles | Breast cancer | Metastasis | Taxane | Survival | Patients | Skeletal muscle | Metastases | Sarcopenia | Musculoskeletal system | Chemotherapy | Computed tomography | Experimental design | Quality | Cancer | toxicity | skeletal muscle index | skeletal muscle gauge | metastatic breast cancer | survival | taxane chemotherapy | muscle attenuation | hospitalizations | sarcopenia
Journal Article
中国化学:英文版, ISSN 1001-604X, 2016, Volume 34, Issue 11, pp. 1165 - 1176
7-epi-Taxane has been achieved efficiently in gram scale from natural taxane via inversion of the 7-hydroxyl group simply using Ag20 as catalyst and DMF as... 
酯化反应 | 前列腺癌 | 合成 | 评价 | 催化活性 | IC50 | 衍生物 | 测定结果 | silver oxide | anticancer activity | taxane | amino acid | epi | C‐13 derivative of taxane | C-13 derivative of taxane | 7-epi-taxane | METABOLISM | TAXOL ANALOGS | AGENTS | CHEMISTRY, MULTIDISCIPLINARY | Care and treatment | Hydroxides | Analysis | Pharmacy | Drugstores | Amino acids | Medicine, Chinese | Drug discovery | Cancer | Rodents
Journal Article
Plant Cell Reports, ISSN 0721-7714, 07/2000, Volume 19, Issue 8, pp. 825 - 830
We have developed a high-yielding procedure for the in vitro propagation of juvenile material ofTaxus baccata involving a combination of seed handling and... 
taxane
Journal Article
Natural Product Research, ISSN 1478-6419, 06/2018, pp. 1 - 7
Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro... 
1-Deoxybaccatin VI | Cytotoxicity | Oxidation | Synthesis | Taxane
Journal Article
Asia-Pacific Journal of Clinical Oncology, ISSN 1743-7555, 2019
Internationally, there has recently been growing interest in the use of neoadjuvant pertuzumab and trastuzumab in patients with non-metastatic HER-2 positive... 
neoadjuvant | pathological complete response | pertuzumab | HER2 | taxane
Journal Article
International journal of molecular sciences, 03/2019, Volume 20, Issue 6
It has been proposed that one of the mechanisms of taxane-site ligand-mediated tubulin activation is modulation of the structure of a switch element (the... 
Journal Article
Oncotarget, ISSN 1949-2553, 02/2019, Volume 10, Issue 11, p. 1209
Adjuvant chemotherapy has an indisputable value for early breast cancer patients. Anthracycline and taxane-based regimens (TaxAC) have not been proven superior... 
Journal Article
Gan to kagaku ryoho. Cancer & chemotherapy, ISSN 0385-0684, 11/2014, Volume 41, Issue 12, pp. 1951 - 1953
Journal Article
Oncotarget, ISSN 1949-2553, 10/2018, Volume 9, Issue 83, pp. 35448 - 35457
Naturally occurring small molecule compounds have long been in the spotlight of pancreatic cancer research as potential therapeutics to prevent cancer... 
Curcumin | Taxane | Natural compounds | Pancreatic cancer | Resveratrol
Journal Article
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