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Nature, ISSN 0028-0836, 01/2011, Volume 469, Issue 7328, pp. 102 - 107
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 09/2012, Volume 44, Issue 9, pp. 1531 - 1540
The number of long-term survivors of patients with various malignancies (>5 years) is increasing mainly owing to advances in cancer therapeutics, but long-term... 
Telomere dysfunction | Side effects | Telomere length | Telomerase | Cancer therapy | LONG-TERM SURVIVORS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | LENGTH | WERNER-SYNDROME | CHILDHOOD-CANCER SURVIVOR | CELL BIOLOGY | HODGKINS-LYMPHOMA | HUMAN FIBROBLASTS | SENESCENCE | EXPRESSION | Serine Proteases - genetics | Gene Expression Regulation, Enzymologic - drug effects | Gamma Rays - adverse effects | Humans | T-Lymphocytes - radiation effects | Telomere Shortening - radiation effects | Telomere - drug effects | RNA, Messenger - metabolism | Telomere-Binding Proteins - genetics | Telomerase - genetics | T-Lymphocytes - metabolism | Antineoplastic Agents - adverse effects | T-Lymphocytes - drug effects | Telomere - metabolism | Telomere-Binding Proteins - metabolism | Telomere Shortening - drug effects | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - genetics | Fibroblasts - metabolism | Telomere - genetics | Aminopeptidases - genetics | Etoposide - adverse effects | Gene Expression Regulation, Enzymologic - radiation effects | RNA, Messenger - genetics | Down-Regulation - drug effects | Telomere - radiation effects | Fibroblasts - radiation effects | T-Lymphocytes - cytology | Fibroblasts - drug effects | Cell Proliferation - drug effects | Fibroblasts - cytology | Doxorubicin - adverse effects | Cell Proliferation - radiation effects | Anthracyclines | RNA | Oncology, Experimental | Radiation | Etoposide | Research | T cells | Cells | Proteins | Chemotherapy | Nuclear radiation | DNA polymerases | Binding proteins | Mitogens | Chromosomes | Cancer | Protein binding
Journal Article
Circulation Research, ISSN 0009-7330, 03/2008, Volume 102, Issue 5, pp. 597 - 606
Journal Article
Journal Article
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2015, Volume 83, pp. 140 - 145
Acrylamide (AAM) has been recently discovered in food as a Maillard reaction product. AAM and glycidamide (GA), its metabolite, have been described as probably... 
Acrylamide | Hayflick's limit | Endothelial cell | Senescence | Telomere length shortening | OXIDATIVE STRESS | HEPATOCYTES | RAT | FOOD SCIENCE & TECHNOLOGY | GLYCIDAMIDE | TOXICITY | CULTURE | PREMATURE SENESCENCE | DISEASE | MICE | TOXICOLOGY | DYSFUNCTION | Biomarkers - metabolism | Endothelium, Vascular - cytology | Epoxy Compounds - metabolism | Cell Survival - drug effects | Apoptosis - drug effects | Humans | Cells, Cultured | Cellular Senescence - drug effects | Toxicity Tests, Subchronic | Endothelium, Vascular - drug effects | Carcinogens - metabolism | Epoxy Compounds - toxicity | Carcinogens - toxicity | Acrylamide - toxicity | Osmolar Concentration | Acrylamide - metabolism | Endothelium, Vascular - metabolism | Human Umbilical Vein Endothelial Cells - cytology | Maillard Reaction | beta-Galactosidase - metabolism | Cell Proliferation - drug effects | Telomere Shortening - drug effects | Medical colleges | Metabolites | Analysis | Skin diseases | Amides | Cells | Endothelium | Index Medicus | Endothelium, Vascular/metabolism | beta-Galactosidase/metabolism | Cellular Senescence/drug effects | Apoptosis/drug effects | Biomarkers/metabolism | Cell Survival/drug effects | Life Sciences | Human Umbilical Vein Endothelial Cells/cytology | Endothelium, Vascular/drug effects | Epoxy Compounds/metabolism | Carcinogens/metabolism | Acrylamide/toxicity | Carcinogens/toxicity | Acrylamide/metabolism | Telomere Shortening/drug effects | Cell Proliferation/drug effects | Endothelium, Vascular/cytology | Epoxy Compounds/toxicity
Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 09/2006, Volume 6, Issue 5, pp. 389 - 406
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 11/2019, Volume 105, Issue 4, pp. 861 - 874
Telomerase is reactivated in non-small cell lung cancer (NSCLC), and it increases cell resistance to irradiation through protecting damaged telomeres and... 
REPAIR | INSTABILITY | IMETELSTAT GRN163L | MECHANISM | ONCOLOGY | RECURRENT | DNA-DAMAGE | RADIATION SENSITIVITY | RADIOTHERAPY | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CHILDREN | Carcinoma, Non-Small-Cell Lung - radiotherapy | Humans | Cellular Senescence - drug effects | Lung Neoplasms - radiotherapy | Enzyme Reactivators - pharmacology | Telomere - drug effects | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Cell Death | Ataxia Telangiectasia Mutated Proteins - antagonists & inhibitors | Female | Telomerase - metabolism | Phosphorylation - drug effects | DNA Damage - drug effects | DNA Repair - drug effects | Lung Neoplasms - enzymology | Radiation-Sensitizing Agents - pharmacology | Sincalide | Enzyme Inhibitors - pharmacology | Enzyme Activation - drug effects | Naphthalenes - pharmacology | Radiation Tolerance - drug effects | Xenograft Model Antitumor Assays | Aminobenzoates - administration & dosage | Animals | Mice, Nude | Naphthalenes - administration & dosage | Aminobenzoates - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Carcinoma, Non-Small-Cell Lung - enzymology | Telomerase - antagonists & inhibitors | Telomere Homeostasis - drug effects | Prevention | Telomeres | Ionizing radiation | Cell death | Analysis | Lung cancer, Small cell | Lung cancer, Non-small cell | Radiotherapy | Telomerase | Index Medicus
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 4/2013, Volume 207, Issue 7, pp. 1157 - 1165
Background. Human immunodeficiency virus (HIV)-infected patients on combination active antiretroviral therapy (cART) are at increased risk of age-related... 
T lymphocytes | HIV/AIDS | Telomeres | Antiretrovirals | HIV | Final causes | Cell lines | Nucleosides | Reverse transcriptase inhibitors | Carts | Disease risks | telomerase | aging | HIV infection | antiretroviral therapy | telomere | INFECTIOUS DISEASES | HUMAN HL60 CELLS | ANTIRETROVIRAL NUCLEOSIDE | ALZHEIMERS-DISEASE | LENGTH | MICROBIOLOGY | IMMUNOLOGY | CANCER | CD8(+) T-CELLS | IN-VITRO | THERAPY | INFECTION | UP-REGULATION | Humans | Middle Aged | Aging - drug effects | Antiretroviral Therapy, Highly Active - adverse effects | Male | Telomere - drug effects | Case-Control Studies | Lamivudine - adverse effects | Reverse Transcriptase Inhibitors - adverse effects | Tenofovir | Young Adult | Telomere Shortening | Adenine - adverse effects | HIV Infections - pathology | Time Factors | Polymerase Chain Reaction | Adult | Deoxycytidine - adverse effects | Female | Telomerase - metabolism | Dideoxynucleosides - adverse effects | Emtricitabine | Adenine - analogs & derivatives | Leukocytes, Mononuclear - drug effects | Zidovudine - adverse effects | Anti-HIV Agents - adverse effects | HIV Infections - virology | Risk Factors | Cells, Cultured | Organophosphonates - adverse effects | HIV - pathogenicity | Enzyme Activation - drug effects | Regression Analysis | Telomere - enzymology | HIV Infections - drug therapy | Leukocytes, Mononuclear - enzymology | Telomerase - antagonists & inhibitors | Deoxycytidine - analogs & derivatives | Complications and side effects | Demographic aspects | Physiological aspects | Aging | Research | Telomerase
Journal Article
Experimental Cell Research, ISSN 0014-4827, 2003, Volume 287, Issue 1, pp. 98 - 105
Bone marrow stromal cells, obtained from postnatal bone marrow, contain progenitors able to differentiate into several mesenchymal lineages. Their use in gene... 
Fibroblast growth factor 2 | Telomeres | Bone marrow stromal cells | Osteoprogenitors | Tissue engineering | bone marrow stromal cells | tissue engineering | STEM-CELLS | telomeres | LONG-TERM CULTURES | PROLIFERATION | CELL BIOLOGY | IN-VITRO | ONCOLOGY | fibroblast growth factor 2 | TELOMERASE ACTIVITY | FIBROBLAST GROWTH-FACTORS | BONE | DIFFERENTIATION | EXPRESSION | MARROW STROMAL CELLS | osteoprogenitors | Stromal Cells - transplantation | Clone Cells - drug effects | Cell Count | Humans | Middle Aged | Fibroblast Growth Factor 2 - pharmacology | Mesoderm - drug effects | Mesoderm - cytology | Telomere - drug effects | Cell Culture Techniques - methods | Bone Marrow Transplantation | Stromal Cells - drug effects | Adult | Bone Marrow Cells - drug effects | Telomerase - metabolism | Telomere - physiology | Colony-Forming Units Assay | Cell Differentiation - physiology | Cell Survival - physiology | DNA-Binding Proteins | Hematopoietic Stem Cells - drug effects | Cell Survival - drug effects | Stromal Cells - metabolism | Hematopoietic Stem Cells - metabolism | Clone Cells - metabolism | Cell Division - drug effects | Cell Division - physiology | Cell Differentiation - drug effects | Hematopoietic Stem Cells - cytology | Adolescent | Telomerase - drug effects | Mesoderm - metabolism | Hematopoietic Stem Cell Transplantation - methods | Bone Marrow Cells - metabolism
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e101291
Neurogenesis continues throughout the lifetime in the hippocampus, while the rate declines with brain aging. It has beenhypothesized that reduced neurogenesis... 
NEURAL STEM-CELLS | ADVANCED GLYCATION | OXIDATIVE DAMAGE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | NEUROGENESIS | MICE | DENTATE GYRUS | ASTROCYTES | DEPENDENT KINASES | MEMORY LOSS | Membrane Glycoproteins - metabolism | Cell Count | Cellular Senescence - drug effects | Male | Ginsenosides - pharmacology | Hippocampus - drug effects | RNA, Messenger - metabolism | Ginsenosides - therapeutic use | SOXB1 Transcription Factors - metabolism | Cognition Disorders - prevention & control | Dentate Gyrus - drug effects | Inflammation Mediators - metabolism | beta-Galactosidase - metabolism | Hippocampus - enzymology | Telomerase - metabolism | Neurogenesis - drug effects | Disease Models, Animal | Cytokines - metabolism | RNA, Messenger - genetics | Cognition Disorders - pathology | Neural Stem Cells - drug effects | Hippocampus - pathology | Antioxidants - pharmacology | Cognition Disorders - drug therapy | Down-Regulation - drug effects | Rats, Sprague-Dawley | Aging - pathology | Nestin - metabolism | Antioxidants - therapeutic use | Animals | Staining and Labeling | Dentate Gyrus - pathology | Galactose - administration & dosage | Neural Stem Cells - metabolism | Telomere Homeostasis - drug effects | Brain | Superoxide | RNA | Galactose | Telomerase | Cell proliferation | Oxidative stress | Neuroprotection | Senescence | Memory | p53 Protein | Impairment | Cognitive ability | Stem cell transplantation | Superoxide dismutase | Neurogenesis | Interleukin 6 | Antioxidants | Embryology | Neurodegeneration | Rodents | Aging | Peroxidase | D-Galactose | Glutathione | Glutathione peroxidase | Cytokines | Tissue engineering | Astrocytes | Cyclin-dependent kinases | Aging (artificial) | Rats | Traditional Chinese medicine | Histology | Inflammation | Injection | Gene expression | Progenitor cells | Cyclin-dependent kinase inhibitor p21 | Stem cells | Cells (biology) | Biomarkers | Neural stem cells | Laboratory animals | Ginseng | Hippocampus | Animal cognition
Journal Article
ONCOTARGET, ISSN 1949-2553, 01/2017, Volume 8, Issue 5, pp. 7301 - 7314
Journal Article