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Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 563 - 570
Mutations in the essential telomerase genes TERT and TR cause familial pulmonary fibrosis; however, in telomerase-null mice, short telomeres predispose to... 
MEDICINE, RESEARCH & EXPERIMENTAL | REVERSE-TRANSCRIPTASE | DISEASE | TETRAHYMENA | RISK | TERMINAL TRANSFERASE | PHENOTYPES | IDIOPATHIC PULMONARY-FIBROSIS | APLASTIC-ANEMIA | COPD | PROCESSIVITY | Chromosome Disorders - epidemiology | Prevalence | Pneumothorax - enzymology | Humans | Middle Aged | Male | Pulmonary Fibrosis - genetics | Pulmonary Fibrosis - epidemiology | Incidence | Telomerase - genetics | Chromosome Disorders - enzymology | Pulmonary Emphysema - genetics | Adult | Female | Registries | Telomerase - metabolism | Telomere - genetics | Chromosome Disorders - pathology | alpha 1-Antitrypsin - genetics | Pneumothorax - epidemiology | Pulmonary Emphysema - pathology | Smoking - genetics | Pulmonary Fibrosis - pathology | Sex Characteristics | Smoking - metabolism | Pneumothorax - pathology | Telomere - pathology | Animals | Smoking - epidemiology | Pulmonary Fibrosis - enzymology | Telomere - enzymology | Sex Factors | Smoking - pathology | Mice | Pneumothorax - genetics | alpha 1-Antitrypsin - metabolism | Mutation | Pulmonary Emphysema - epidemiology | Chromosome Disorders - genetics | Pulmonary Emphysema - enzymology | Smokers | Gene mutations | Emphysema, Pulmonary | Genetic aspects | Telomerase | Identification and classification | Health aspects | Risk factors | Enzymes | Liver diseases | Pulmonary fibrosis | Cloning | Cell division | Chronic obstructive pulmonary disease | Emphysema | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 12/2008, Volume 132, Issue 12, pp. 1896 - 1902
Context.-We previously found telomere repeat amplification protocol (TRAP) in situ helpful in the diagnosis of malignancy in effusions, whereas varying... 
FLUIDS | MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANCY | PLEURAL EFFUSIONS | MEDICAL LABORATORY TECHNOLOGY | PATHOLOGY | CANCER | MESOTHELIAL CELLS | TRAP ASSAY | LYMPHOCYTES | Enzyme-Linked Immunosorbent Assay - methods | Peritoneal Neoplasms - pathology | Mesothelioma - pathology | Nucleic Acid Amplification Techniques - methods | Pericardial Effusion - diagnosis | Humans | Ascitic Fluid - pathology | Pericardial Effusion - pathology | Pleural Neoplasms - diagnosis | Mesothelioma - diagnosis | Pleural Effusion, Malignant - pathology | Pericardial Effusion - enzymology | Peritoneal Neoplasms - diagnosis | Peritoneal Neoplasms - enzymology | Ascitic Fluid - enzymology | Sensitivity and Specificity | Mesothelioma - enzymology | Pleural Neoplasms - enzymology | Telomerase - metabolism | Retrospective Studies | Pleural Effusion, Malignant - enzymology | Pleural Neoplasms - pathology | Pleural Effusion, Malignant - diagnosis | Telomere - genetics | Fluorescence | Telomerase | Enzyme-linked immunosorbent assay | Mesothelioma/diagnosis/enzymology/pathology | Peritoneal Neoplasms/diagnosis/enzymology/pathology | Telomere/genetics | Telomerase/metabolism | Pleural Neoplasms/diagnosis/enzymology/pathology | Pleural Effusion; Malignant/diagnosis/enzymology/pathology | Ascitic Fluid/enzymology/pathology | Enzyme-Linked Immunosorbent Assay/methods | Pericardial Effusion/diagnosis/enzymology/pathology | Nucleic Acid Amplification Techniques/methods
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2016, Volume 138, Issue 12, pp. 2905 - 2914
Journal Article
Journal Article
Neoplasia, ISSN 1476-5586, 09/2000, Volume 2, Issue 5, pp. 433 - 440
Telomerase, a cellular reverse transcriptase, adds telomeric repeats to chromosome ends. In normal human somatic cells, telomerase is repressed and telomeres... 
dominant-negative inhibitor | apoptosis | alternate splicing | human telomerase | telomere | Human telomerase | Telomere | Dominant-negative inhibitor | Alternate splicing | Apoptosis | NORMAL HUMAN-CELLS | LIFE-SPAN | TUMOR-CELLS | RETROVIRAL VECTORS | CANCER | ONCOLOGY | REVERSE-TRANSCRIPTASE HTERT | HUMAN FIBROBLASTS | GENE-TRANSFER | EXPRESSION | IMMORTALIZATION | Protein Subunits | Sequence Deletion | Fibroblasts - enzymology | Skin - cytology | Alternative Splicing | RNA | Telomere - ultrastructure | Humans | DNA, Complementary - genetics | Recombinant Fusion Proteins - physiology | Cell Line - enzymology | Lung Neoplasms - pathology | Male | Lung - cytology | Tumor Cells, Cultured - enzymology | Telomerase - genetics | Transfection | Genes, Dominant | Retroviridae - genetics | Telomerase - physiology | Cell Transformation, Neoplastic - genetics | Carcinoma - enzymology | Telomere - metabolism | Carcinoma - pathology | Neoplasm Proteins - genetics | DNA-Binding Proteins | Carcinoma, Non-Small-Cell Lung - pathology | Prostatic Neoplasms - pathology | Catalytic Domain | Lung Neoplasms - enzymology | Neoplasm Proteins - chemistry | Chromosomes, Human - ultrastructure | Blotting, Western | Genetic Vectors - genetics | Cell Line, Transformed - enzymology | Telomerase - chemistry | Chromosome Aberrations | Prostatic Neoplasms - enzymology | Peptide Chain Termination, Translational - genetics | Fetal Proteins - genetics | Fibroblasts - cytology | Carcinoma, Non-Small-Cell Lung - enzymology | Telomerase - antagonists & inhibitors | Fetal Proteins - chemistry
Journal Article