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Molecular Pharmaceutics, ISSN 1543-8384, 06/2015, Volume 12, Issue 6, pp. 2026 - 2039
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2014, Volume 96, Issue 3, pp. 349 - 359
The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and... 
P4502B6 ACTIVITY | VORICONAZOLE | LC-MS/MS | SINGLE-POINT | ORAL MIDAZOLAM | VOLUNTEERS | IN-VIVO | PHARMACOLOGY & PHARMACY | DRUG-METABOLIZING-ENZYMES | KAROLINSKA COCKTAIL | BUPROPION HYDROXYLATION | Predictive Value of Tests | Pharmaceutical Preparations - blood | Caffeine - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Dried Blood Spot Testing | Humans | Omeprazole - blood | Bupropion - blood | Midazolam - administration & dosage | Substrate Specificity | Male | Chromatography, High Pressure Liquid | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Coffee | Terfenadine - administration & dosage | Caffeine - pharmacokinetics | Feasibility Studies | Enzyme Inhibitors - administration & dosage | Young Adult | Chromatography, Reverse-Phase | Tandem Mass Spectrometry | Capsules | Spectrometry, Mass, Electrospray Ionization | Flurbiprofen - administration & dosage | Adult | Dextromethorphan - pharmacokinetics | Terfenadine - blood | ATP-Binding Cassette, Sub-Family B, Member 1 - blood | Pharmaceutical Preparations - administration & dosage | Terfenadine - pharmacokinetics | Bupropion - pharmacokinetics | Flurbiprofen - pharmacokinetics | Cytochrome P-450 Enzyme System - blood | Administration, Oral | Isoenzymes | Caffeine - blood | Omeprazole - administration & dosage | Terfenadine - analogs & derivatives | Omeprazole - pharmacokinetics | Carbonated Beverages | Midazolam - pharmacokinetics | Bupropion - administration & dosage | Dextromethorphan - blood | Flurbiprofen - blood | Phenotype | Pilot Projects | Midazolam - blood | Dextromethorphan - administration & dosage | Usage | Glycoproteins | Liquid chromatography | Research | Pharmacokinetics | Cytochrome P-450 | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 10/2008, Volume 84, Issue 4, pp. 506 - 512
Ritonavir diminishes methadone plasma concentrations, an effect attributed to CYP3A induction, but the actual mechanisms are unknown. We determined short‐term... 
P4503A CYP3A | DRUG-INTERACTIONS | GRAPEFRUIT JUICE | CYTOCHROME-P450 3A ACTIVITY | PHARMACOLOGY & PHARMACY | ST-JOHNS-WORT | FEXOFENADINE PHARMACOKINETICS | HEALTHY-VOLUNTEERS | BLOOD-BRAIN-BARRIER | SHORT-TERM | ALFENTANIL
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 03/2015, Volume 104, Issue 3, pp. 955 - 961
In pharmacokinetic evaluation of mice, using serial sampling methods rather than a terminal blood sampling method could reduce the number of animals needed and... 
serial sampling method | drug interactions | preclinical pharmacokinetics | Preclinical pharmacokinetics | Drug interactions | Serial sampling method | ANTIPYRINE | CLEARANCE | CHEMISTRY, MEDICINAL | MOUSE | CHIMERIC MICE | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | 1-AMINOBENZOTRIAZOLE | PREDICTION | PREGNANE X RECEPTOR | HUMANIZED LIVER | INHIBITION | PHARMACOLOGY & PHARMACY | Triazoles - administration & dosage | Biological Availability | Male | Drug Monitoring - methods | Ibuprofen - blood | Terfenadine - administration & dosage | Organic Anion Transporters - metabolism | Drug Interactions | Veins | Tail - blood supply | Models, Animal | Rifampin - administration & dosage | Terfenadine - blood | Terfenadine - pharmacokinetics | Organic Anion Transporters - antagonists & inhibitors | Reproducibility of Results | Administration, Oral | Ibuprofen - pharmacokinetics | Mice, Inbred C57BL | Terfenadine - analogs & derivatives | Ibuprofen - administration & dosage | Cytochrome P-450 Enzyme Inhibitors - administration & dosage | Pravastatin - blood | Administration, Intravenous | Animals | Antipyrine - administration & dosage | Pravastatin - administration & dosage | Antipyrine - pharmacokinetics | Antipyrine - blood | Blood Specimen Collection - methods | Pravastatin - pharmacokinetics | Complications and side effects | Medical examination | Pharmacists | Blood | Ibuprofen
Journal Article
Journal Article