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Organic Letters, ISSN 1523-7060, 01/2014, Volume 16, Issue 1, pp. 290 - 293
An efficient methodology for ligation at glutamate (Glu) is described. A γ-thiol-Glu building block was accessed in only three steps from protected glutamic... 
PROLINE LIGATION | AMINO-ACID SYNTHESIS | ASPARTIC-ACID | NATIVE CHEMICAL LIGATION | CHEMISTRY, ORGANIC | CYSTEINE | SULFENYLATION | DESELENIZATION | PROTEIN-SYNTHESIS | HIGHLY EFFICIENT | BETA | Molecular Structure | Peptides - chemical synthesis | Teriparatide - chemistry | Peptides - chemistry | Teriparatide - chemical synthesis | Glutamic Acid - chemistry
Journal Article
Organic Letters, ISSN 1523-7060, 01/2014, Volume 16, Issue 2, pp. 512 - 515
Chemical ligation protocols were explored for generating semisynthetic peptoid–protein hybrid architectures containing a native serine residue at the ligation... 
CHEMISTRY, ORGANIC | SITE | HORMONE | PEPTIDE | THREONINE | SCAFFOLD | Peptide Fragments - chemistry | Ligation | Teriparatide - analogs & derivatives | Molecular Structure | Peptoids - chemical synthesis | Proteins - chemistry | Teriparatide - chemistry | Proteins - chemical synthesis | Serine - chemistry | Peptoids - chemistry | Aldehydes - chemistry
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 07/2016, Volume 14, Issue 26, pp. 6231 - 6243
The cyclohexapeptide natural product dianthin G promotes osteoblast (bone-forming cell) proliferation in vitro at nanomolar concentrations, and is therefore... 
Humans | Middle Aged | Osteoblasts - drug effects | Cells, Cultured | Peptides, Cyclic - pharmacology | Structure-Activity Relationship | Peptides, Cyclic - chemistry | Dose-Response Relationship, Drug | Animals | Peptides, Cyclic - chemical synthesis | Aged | Cell Proliferation - drug effects | Mice | Molecular Structure
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2009, Volume 52, Issue 21, pp. 6599 - 6605
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2019, Volume 62, Issue 3, pp. 1362 - 1372
Current therapies of steroid hormone-dependent diseases predominantly alter steroid hormone concentrations (or their actions) in plasma, in target and... 
CELLS | CHEMISTRY, MEDICINAL | ENZYME | ESTRADIOL | TISSUE | ESTROGEN | ENDOMETRIAL | TERIPARATIDE | MODEL | EXPRESSION
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 26, pp. 6231 - 6243
The cyclohexapeptide natural product dianthin G promotes osteoblast (bone-forming cell) proliferation in vitro at nanomolar concentrations, and is therefore... 
RING-CLOSING METATHESIS | STABILITY | DICARBA ANALOGS | CHEMISTRY, ORGANIC | OLEFIN METATHESIS | TERIPARATIDE | INHIBITORS | MULTIPLE N-METHYLATION | SELECTIVITY | CYCLIC-PEPTIDES | OSTEOPOROSIS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1987, Volume 84, Issue 14, pp. 5048 - 5052
A protein with biological activities similar to parathyroid hormone (PTH) has been purified from serum-free culture medium obtained from a human lung cancer... 
Cell culture techniques | Elution | Bioassay | Gels | Ungulates | Radioimmunoassay | Cell lines | Amino acids | Kidney cells | Tumors
Journal Article
Journal of Photochemistry & Photobiology, B: Biology, ISSN 1011-1344, 1992, Volume 12, Issue 2, pp. 193 - 201
Journal Article
Journal Article
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