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Molecules (Basel, Switzerland), ISSN 1420-3049, 2010, Volume 15, Issue 11, pp. 7532 - 7546
The chemical composition and antibacterial activity of essential oils from 10 commonly consumed herbs: Citrus aurantium, C. limon, Lavandula angustifolia,... 
Herbs | Human pathogens | Structure-activity | Essential oils | Microdilution method | Disc-diffusion | Natural antimicrobial agents | Food spoilage bacteria | LISTERIA-MONOCYTOGENES | disc-diffusion | microdilution method | FUNGI | ESCHERICHIA-COLI | CHEMISTRY, ORGANIC | OREGANO ESSENTIAL OIL | SALMONELLA-ENTERITIDIS | herbs | food spoilage bacteria | CHEMICAL-COMPOSITION | natural antimicrobial agents | ANTIFUNGAL ACTIVITIES | essential oils | human pathogens | structure-activity | Salvia officinalis - chemistry | Staphylococcus epidermidis - drug effects | Oils, Volatile - chemistry | Cyclohexenes - chemistry | Thymus Plant - chemistry | Citrus - chemistry | Oils, Volatile - pharmacology | Menthol - chemistry | Micrococcus luteus - drug effects | Terpenes - pharmacology | Monoterpenes - pharmacology | Terpenes - chemistry | Bridged Bicyclo Compounds - chemistry | Cyclohexanols - chemistry | Anti-Bacterial Agents - chemistry | Cyclohexanols - pharmacology | Camphor - pharmacology | Thymol - chemistry | Lavandula - chemistry | Camphor - chemistry | Enterobacter cloacae - drug effects | Plants, Medicinal - chemistry | Salmonella enteritidis - drug effects | Bridged Bicyclo Compounds - pharmacology | Pseudomonas aeruginosa - drug effects | Mentha piperita - chemistry | Menthol - pharmacology | Mentha spicata - chemistry | Thymol - pharmacology | Cyclohexenes - pharmacology | Monoterpenes - chemistry | Escherichia - drug effects | Anti-Bacterial Agents - pharmacology | Origanum - chemistry | Staphylococcus aureus - drug effects | Matricaria - chemistry | Proteus mirabilis - drug effects | Bacillus subtilis - drug effects
Journal Article
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 2016, Volume 60, Issue 4, pp. 2281 - 2291
Deciphering the mode of action (MOA) of new antibiotics discovered through phenotypic screening is of increasing importance. Metabolomics offers a potentially... 
TARGET | NATURAL-PRODUCT | THYMIDYLATE KINASE | BIOSYNTHESIS | ESCHERICHIA-COLI | ALANINE LIGASE | D-CYCLOSERINE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | STAPHYLOCOCCUS-AUREUS | MASS-SPECTROMETRY | PATHOGENS | Acyltransferases - antagonists & inhibitors | Metabolomics | Nucleoside-Phosphate Kinase - genetics | Ceftazidime - pharmacology | Escherichia coli - drug effects | Humans | Triclosan - metabolism | Triclosan - pharmacology | Acyltransferases - metabolism | Threonine - metabolism | Acyltransferases - genetics | Fosfomycin - metabolism | Pyrimidines - metabolism | DNA, Bacterial - antagonists & inhibitors | Ceftazidime - metabolism | Cell Wall - drug effects | Terpenes - antagonists & inhibitors | Terpenes - metabolism | Carbonyl Cyanide m-Chlorophenyl Hydrazone - pharmacology | Mass Spectrometry | Escherichia coli - metabolism | HEK293 Cells | Chromatography, Liquid | Hydroxamic Acids - pharmacology | Fosfomycin - analogs & derivatives | Carbonyl Cyanide m-Chlorophenyl Hydrazone - metabolism | Gene Expression | DNA, Bacterial - biosynthesis | Fosfomycin - pharmacology | Nucleoside-Phosphate Kinase - antagonists & inhibitors | Anti-Bacterial Agents - metabolism | Adenosine - pharmacology | Cell Wall - chemistry | Pyrimidines - pharmacology | Threonine - analogs & derivatives | Hydroxamic Acids - metabolism | Threonine - pharmacology | Metabolome - drug effects | Escherichia coli - genetics | Cell Wall - metabolism | Adenosine - metabolism | Anti-Bacterial Agents - pharmacology | Nucleoside-Phosphate Kinase - metabolism
Journal Article
CURRENT MEDICINAL CHEMISTRY, ISSN 0929-8673, 2017, Volume 24, Issue 14, pp. 1453 - 1468
Background: Monocyte chemoattractant protein-1 (MCP-1) is a member of the CC chemokine family that plays a key role in the inflammatory process. It has been... 
plant metabolites | OXIDATIVE STRESS | SIGNALING PATHWAYS | CHEMISTRY, MEDICINAL | INFLAMMATORY RESPONSES | plant extracts | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCED MCP-1 EXPRESSION | PHENETHYL ESTER SUPPRESSES | CAFFEIC ACID | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | Diabetes | TNF-ALPHA | monocyte chemoattractant protein-1 (MCP-1) | NF-KAPPA-B | CCR2 | ADIPOSE-TISSUE | Phenols - isolation & purification | Plant Extracts - chemistry | Anthocyanins - isolation & purification | Capsaicin - pharmacology | Plant Extracts - pharmacology | Humans | Alkaloids - isolation & purification | Capsaicin - chemistry | Stilbenes - chemistry | Diabetes Mellitus, Type 2 - metabolism | Stilbenes - pharmacology | Terpenes - pharmacology | Terpenes - chemistry | Chemokine CCL2 - metabolism | Flavonoids - pharmacology | Phenols - pharmacology | Sterols - pharmacology | Anthocyanins - pharmacology | Alkaloids - pharmacology | Terpenes - isolation & purification | Sterols - chemistry | Diabetes Complications - metabolism | Diabetes Complications - drug therapy | Plant Extracts - isolation & purification | Capsaicin - isolation & purification | Anthocyanins - chemistry | Sterols - isolation & purification | Animals | Stilbenes - isolation & purification | Chemokine CCL2 - biosynthesis | Phenols - chemistry | Flavonoids - isolation & purification | Diabetes Mellitus, Type 2 - drug therapy | Flavonoids - chemistry | Alkaloids - chemistry | Adipose tissues | CC chemokine receptors | Saponins | Adipose tissue | Capsaicin | Macrophages | Phenolic acids | Alkaloids | Metabolites | CCR2 protein | Sterols | Diabetes mellitus (non-insulin dependent) | Obesity | Complications | Diabetes mellitus | Pharmacology | Inflammation | Plants | Insulin | Fatty acids | Chemical compounds | Plant extracts | Flavonoids | Molecular modelling | Monocyte chemoattractant protein | Phenols | Anthocyanins | Infiltration | Terpenes | Chemokines | Monocyte chemoattractant protein 1
Journal Article
Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 8, p. 1892
Extensive phytochemical analysis of different root fractions of Jatropha pelargoniifolia Courb. (Euphorbiaceae) has resulted in the isolation and... 
Alkaloids | Flavonoids | Analgesic | Jatropha pelargoniifolia | Antipyretic | Diterpenes | Coumarinolignans | Anti-inflammatory | RAT | analgesic | BIOCHEMISTRY & MOLECULAR BIOLOGY | alkaloids | diterpenes | HORDENINE | CHEMISTRY, MULTIDISCIPLINARY | antipyretic | GOSSYPIFOLIA | anti-inflammatory | PLANTS | flavonoids | coumarinolignans | CURCAS LINN | EUPHORBIACEAE | CONSTITUENTS | EXTRACT | Analgesics - pharmacology | Male | Indoles - isolation & purification | Fever - physiopathology | Coumarins - isolation & purification | Glycosides - isolation & purification | Anti-Inflammatory Agents - isolation & purification | Antipyretics - chemistry | Glycosides - chemistry | Analgesics - isolation & purification | Phytochemicals - chemistry | Terpenes - isolation & purification | Anti-Inflammatory Agents - pharmacology | Rats | Pyrimidines - pharmacology | Glycosides - pharmacology | Coumarins - pharmacology | Phytochemicals - isolation & purification | Biogenic Monoamines - pharmacology | Analgesics - chemistry | Pain - physiopathology | Plant Roots - chemistry | Flavonoids - isolation & purification | Mice | Antipyretics - pharmacology | Fever - drug therapy | Flavonoids - chemistry | Biogenic Monoamines - chemistry | Plant Extracts - chemistry | Rats, Wistar | Coumarins - chemistry | Antipyretics - isolation & purification | Pyrimidines - chemistry | Jatropha - metabolism | Terpenes - pharmacology | Pyrimidines - isolation & purification | Terpenes - chemistry | Pain - drug therapy | Indoles - pharmacology | Flavonoids - pharmacology | Hyperthermia, Induced - methods | Plant Roots - metabolism | Nitric Oxide - antagonists & inhibitors | Edema - drug therapy | Jatropha - chemistry | Hyperalgesia - physiopathology | Secondary Metabolism | Biogenic Monoamines - isolation & purification | Animals | Anti-Inflammatory Agents - chemistry | Hyperalgesia - drug therapy | Edema - physiopathology | Indoles - chemistry | Phytochemicals - pharmacology | Tyramine | Animal models | Yeast | Antiinflammatory agents | Indole | Inflammation | Coumarin | Secondary metabolites | Phytochemicals | Metabolites | Analgesics | Nitric oxide | Hyperthermia
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