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Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 2006, Volume 114, Issue 1, pp. 134 - 141
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 08/2016, Volume 34, pp. 17 - 29
Benzo(a)pyrene [B(a)P] is an environmental toxicant that alters the steroidogenic profile of testis and induces testicular dysfunction. In the present study,... 
Testis | ATF2 | B(a)P | ROS | iNOS | p38 MAPK | Apoptosis | P38 MAPK | INOS | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | LIPID-PEROXIDATION | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR-KAPPA-B | CYTOCHROME-C | NUTRITION & DIETETICS | INHALED BENZO(A)PYRENE | ARYL-HYDROCARBON RECEPTOR | CELLULAR-RESPONSES | ENDOTHELIAL-CELLS | Testis - metabolism | Receptors, Aryl Hydrocarbon - antagonists & inhibitors | Stilbenes - therapeutic use | Apoptosis - drug effects | Benzo(a)pyrene - administration & dosage | Cytochrome P-450 CYP1A1 - antagonists & inhibitors | Male | Promoter Regions, Genetic - drug effects | Testis - drug effects | Basic Helix-Loop-Helix Transcription Factors - metabolism | Environmental Pollutants - administration & dosage | Environmental Pollutants - toxicity | Testosterone - blood | Basic Helix-Loop-Helix Transcription Factors - agonists | Benzo(a)pyrene - toxicity | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptors, Aryl Hydrocarbon - genetics | Testosterone - agonists | Infertility, Male - pathology | Receptors, Aryl Hydrocarbon - agonists | Testis - pathology | Active Transport, Cell Nucleus - drug effects | Testosterone - antagonists & inhibitors | Benzo(a)pyrene - antagonists & inhibitors | Oxidative Stress - drug effects | Nitric Oxide Synthase Type II - metabolism | Infertility, Male - prevention & control | Stilbenes - adverse effects | Cytochrome P-450 CYP1A1 - genetics | Activating Transcription Factor 2 - antagonists & inhibitors | Rats, Wistar | Activating Transcription Factor 2 - genetics | Dose-Response Relationship, Drug | Nitric Oxide Synthase Type II - antagonists & inhibitors | Environmental Pollutants - antagonists & inhibitors | Receptors, Aryl Hydrocarbon - metabolism | Dietary Supplements - adverse effects | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Cytochrome P-450 CYP1A1 - metabolism | Activating Transcription Factor 2 - metabolism | Gene Expression Regulation - drug effects | Antioxidants - therapeutic use | Animals | MAP Kinase Signaling System - drug effects | Nitric Oxide Synthase Type II - genetics | Activating Transcription Factor 2 - agonists | Antioxidants - adverse effects | Infertility, Male - metabolism | Infertility, Male - chemically induced | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7560, pp. 347 - 351
Prostate cancer resistance to castration occurs because tumours acquire the metabolic capability of converting precursor steroids to 5... 
ANDROGEN RECEPTOR | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | CYP17A1 INHIBITION | MECHANISM | TESTOSTERONE | RATIONALE | MULTIDISCIPLINARY SCIENCES | INCREASED SURVIVAL | CHEMOTHERAPY | EXPOSURE | ENZALUTAMIDE | Chromatin - metabolism | Prostatic Neoplasms - metabolism | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Androgen Receptor Antagonists - therapeutic use | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Androgens - biosynthesis | Male | Androstenes - pharmacology | Androgen Receptor Antagonists - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Biotransformation | Cell Division | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Prostatic Neoplasms - drug therapy | Dihydrotestosterone - metabolism | Phenylthiohydantoin - pharmacology | Prostatic Neoplasms - pathology | Androstenes - therapeutic use | 5-alpha Reductase Inhibitors - therapeutic use | Prostatic Neoplasms, Castration-Resistant - drug therapy | Phenylthiohydantoin - analogs & derivatives | Androgen Receptor Antagonists - metabolism | Xenograft Model Antitumor Assays | Androstenes - chemistry | Animals | Biosynthetic Pathways - drug effects | Survival Analysis | 5-alpha Reductase Inhibitors - pharmacology | Androstenes - metabolism | Prostatic Neoplasms - enzymology | Mice | Steroid 17-alpha-Hydroxylase - metabolism | 5-alpha Reductase Inhibitors - metabolism | Androgens - metabolism | Enzymes | Testosterone | Androgens | Metabolites | Ligands | Gene expression | Prostate cancer | Tumors | Index Medicus
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2012, Volume 187, Issue 4, pp. 1498 - 1504
Journal Article
Environment International, ISSN 0160-4120, 01/2015, Volume 74, pp. 60 - 70
Brominated flame-retardants (BFRs) are used in industrial products to reduce the risk of fire. However, their continuous release into the environment is a... 
Human | Gene regulation | LAT | PSA | DIPHENYL ETHERS PBDES | PROTEIN | TESTOSTERONE | SPONTANEOUS BEHAVIOR | AMINO-ACID TRANSPORTER | ENVIRONMENTAL SCIENCES | IN-VITRO | MESSENGER-RNA | PROSTATE-CANCER | GENE-EXPRESSION | AGONIST | Hydrocarbons, Brominated - metabolism | Prostate-Specific Antigen - genetics | Prostatic Neoplasms - metabolism | Endocrine Disruptors - chemistry | Humans | Receptors, Androgen - metabolism | Transcriptional Activation - drug effects | Amino Acid Transport System y+L - biosynthesis | Male | Flame Retardants - pharmacology | Androgen Receptor Antagonists - pharmacology | Hydrocarbons, Brominated - pharmacology | Androgen Receptor Antagonists - metabolism | Blood-Brain Barrier - metabolism | Prostatic Neoplasms - genetics | Amino Acid Transport System y+L - genetics | Androgen Receptor Antagonists - chemistry | Flame Retardants - metabolism | Cell Line, Tumor | Receptors, Androgen - chemistry | Hydrocarbons, Brominated - chemistry | Molecular Docking Simulation | Fireproofing agents | Neurons | Prostate-specific antigen | Analysis | Hormones, Sex | Prostate cancer | Neurophysiology | Index Medicus | Brain | Receptors | Genes | Amino acids | Mathematical models | Gene expression | Ethers | Miljövetenskap | Naturvetenskap | Gene regulation; Human; PSA; LAT | Biology | Biologi | Natural Sciences | Earth and Related Environmental Sciences | Environmental Sciences | Geovetenskap och miljövetenskap
Journal Article