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British Journal of Cancer, ISSN 0007-0920, 03/2017, Volume 116, Issue 7, pp. 937 - 943
Background: Renal cell carcinoma (RCC) is one of the most lethal genitourinary cancers. The presence of androgen receptor (AR) in RCC has recently been shown... 
GPRC6A | GLUCOCORTICOID-RECEPTOR | ONCOLOGY | PATHWAY | PROSTATE-CANCER | RESISTANCE | EXPRESSION | PROGRESSION | Prostatic Neoplasms - metabolism | Prognosis | Apoptosis - drug effects | Humans | Receptors, Androgen - metabolism | Androgens - biosynthesis | Male | Kidney Neoplasms - metabolism | Immunoenzyme Techniques | Prostatic Neoplasms, Castration-Resistant - pathology | Testosterone - metabolism | Abiraterone Acetate - pharmacology | Female | Receptors, Androgen - chemistry | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Carcinoma, Renal Cell - drug therapy | Real-Time Polymerase Chain Reaction | Prostatic Neoplasms - drug therapy | Dihydrotestosterone - metabolism | Phenylthiohydantoin - pharmacology | Prostatic Neoplasms - pathology | Carcinoma, Renal Cell - pathology | RNA, Messenger - genetics | Prostatic Neoplasms, Castration-Resistant - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | Prostatic Neoplasms, Castration-Resistant - metabolism | Blotting, Western | Phenylthiohydantoin - analogs & derivatives | Orchiectomy | Xenograft Model Antitumor Assays | Carcinoma, Renal Cell - metabolism | Animals | Receptors, Androgen - genetics | Mice, Nude | Kidney Neoplasms - pathology | Cell Proliferation - drug effects | Mice | Kidney Neoplasms - drug therapy | Index Medicus | renal cell carcinoma | androgen | androgen receptor | Molecular Diagnostics | intracrine | abiraterone acetate | enzalutamide
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 02/2018, Volume 159, Issue 2, pp. 1119 - 1129
Journal Article
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2017, Volume 21, Issue 8, pp. 1636 - 1647
The aim of this study was to investigate whether nandrolone decanoate ( ND ) use affects testosterone production and testicular morphology in a model of... 
MMP | MUC | TJP | testosterone | blood–testis barrier | nandrolone decanoate | TJP1 | MUC1 | MMP-2 | MMP-9 | SPERMATOGENESIS | MEDICINE, RESEARCH & EXPERIMENTAL | ANDROGEN RECEPTOR | APOPTOSIS | ADULT RATS | SERTOLI-CELLS | CELL BIOLOGY | ANABOLIC-STEROIDS | IN-VITRO | blood-testis barrier | LARGE-BOWEL | RAT LEYDIG-CELLS | EXPRESSION | Testis - metabolism | Male | Protein Transport - drug effects | Sedentary Lifestyle | Testis - drug effects | Tissue Inhibitor of Metalloproteinases - genetics | Matrix Metalloproteinase 9 - metabolism | Anabolic Agents - pharmacology | Matrix Metalloproteinase 9 - genetics | Zonula Occludens-1 Protein - metabolism | Physical Conditioning, Animal | Zonula Occludens-1 Protein - genetics | Mucin-1 - metabolism | Signal Transduction | Blood-Testis Barrier - metabolism | Matrix Metalloproteinase 2 - metabolism | Gene Expression Regulation | Nandrolone - analogs & derivatives | Testosterone - biosynthesis | Tissue Inhibitor of Metalloproteinases - metabolism | Matrix Metalloproteinase 2 - genetics | Animals | Nandrolone - pharmacology | Testosterone - antagonists & inhibitors | Blood-Testis Barrier - drug effects | Mice | Mucin-1 - genetics | Immunohistochemistry | Testosterone | Enzymes | Deregulation | Analysis | Physiological aspects | Liquid chromatography | Gene expression | Mass spectrometry | Neodymium | Stimulation | Biosynthesis | Cages | Blood | Risk factors | Degradation | Nortestosterone | Metalloproteinase | Abuse | Mass spectroscopy | Bioavailability | Gelatinase A | Polymerase chain reaction | Serum levels | Androgens | Mucin | Infertility | Internalization | Morphology | Testes | Immunofluorescence | Index Medicus | MMP‐2 | MMP‐9 | Original
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 12/2012, Volume 72, Issue 23, pp. 6142 - 6152
Androgen receptor (AR) signaling persists in castration-resistant prostate carcinomas (CRPC), because of several mechanisms that include increased AR... 
STEROIDOGENESIS | SELECTIVE INHIBITOR | DIHYDROTESTOSTERONE LEVELS | ONCOLOGY | ABIRATERONE ACETATE | RECEPTOR | INCREASED SURVIVAL | CYP17 INHIBITOR | CASTRATION | I CLINICAL-TRIAL | HORMONAL-THERAPY | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Immunohistochemistry | Neoplasms, Hormone-Dependent - metabolism | Prostatic Neoplasms - metabolism | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Androgens - biosynthesis | Data Mining | Male | Hydroxyprostaglandin Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - genetics | RNA, Messenger - biosynthesis | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Cytochrome P-450 CYP3A - genetics | Receptors, Androgen - biosynthesis | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - enzymology | Cytochrome P-450 CYP3A - biosynthesis | Prostatic Neoplasms - pathology | RNA, Messenger - genetics | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxyprostaglandin Dehydrogenases - genetics | Orchiectomy | Gene Expression Regulation, Enzymologic | Receptors, Androgen - genetics | Aldo-Keto Reductase Family 1 Member C3 | Cytochrome P-450 CYP3A - metabolism | Neoplasms, Hormone-Dependent - pathology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - biosynthesis | Cell Line, Tumor | Prostatic Neoplasms - enzymology | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | Index Medicus | abiraterone | androgen synthesis | testosterone | dihydrotestosterone | AKR1C3 | CYP17 | MDV3100 (enzalutamide) | Prostate cancer
Journal Article
Reproductive Toxicology, ISSN 0890-6238, 01/2016, Volume 59, pp. 139 - 146
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e79686 - e79686
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2017, Volume 127, Issue 8, pp. 3167 - 3176
Proinflammatory leukotrienes (LTs) are produced by 5-lipoxygenase (5-LO) aided by 5-LO-activating protein (FLAP). LT biosynthesis inhibitors are currently... 
MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | MYOCARDIAL-INFARCTION | INFLAMMATION | ASTHMA | DOUBLE KNOCKOUT MICE | 5-LIPOXYGENASE-ACTIVATING PROTEIN FLAP | AUTOIMMUNE-DISEASE | GENDER-DIFFERENCES | DRUG RESPONSES | IN-SITU | Hydroxyurea - analogs & derivatives | Hydroxyurea - pharmacology | Arachidonate 5-Lipoxygenase - metabolism | Rats, Wistar | 5-Lipoxygenase-Activating Proteins - metabolism | Humans | Leukotrienes - biosynthesis | Sulindac - administration & dosage | Rats | Male | Sulindac - analogs & derivatives | Testosterone - metabolism | Testosterone - administration & dosage | Animals | Pyrroles - administration & dosage | Sex Factors | Female | Mice | Androgens - metabolism | Leukocytes - metabolism | Lipoxygenase Inhibitors - pharmacology | Dihydrotestosterone - metabolism | Androgens | Synthesis | Research | Sexism | Leukotrienes | Sulfide | Heart attacks | Platelet-activating factor | Bias | Sex | Biosynthesis | Leukocytes | Males | Proteins | Airway management | Dihydrotestosterone | Efficiency | Rodents | Sulindac | Atherosclerosis | Arachidonate 5-lipoxygenase | Supplementation | Neutrophils | Protein biosynthesis | Sex differences | Gender differences | Inflammation | Asthma | Testosterone | Exudates | Lipoxygenase | Cardiovascular diseases | Females | Index Medicus | Abridged Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 04/2002, Volume 94, Issue 8, pp. 606 - 616
Journal Article