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PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, pp. e0171476 - e0171476
Seven metabolites were obtained from the microbial transformation of anabolic-androgenic steroid mibolerone (1) with Cunninghamella blakesleeana, C.... 
COLON-CANCER | BIOCATALYSTS | SURVIVAL | CELLS | CISPLATIN-INDUCED CYTOTOXICITY | PRODUCTS | MULTIDISCIPLINARY SCIENCES | HYDROXYLATION | ANDROGEN | MICROBIAL TRANSFORMATION | CERVICAL-CANCER | NIH 3T3 Cells | Antiprotozoal Agents - metabolism | Humans | 17-Ketosteroids - pharmacology | Chromatography, High Pressure Liquid | Carbonic Anhydrases - chemistry | Nandrolone - metabolism | Testosterone Congeners - chemistry | Antineoplastic Agents - metabolism | Testosterone Congeners - isolation & purification | 17-Ketosteroids - chemistry | Saccharomycetales - chemistry | Cunninghamella - metabolism | Antineoplastic Agents - isolation & purification | Biotransformation | Leishmania major - growth & development | Glucuronidase - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Molecular Structure | Monophenol Monooxygenase - chemistry | Cell Survival - drug effects | Saccharomycetales - drug effects | 17-Ketosteroids - metabolism | Cunninghamella - drug effects | Hydroxylation | Leishmania major - drug effects | 17-Ketosteroids - isolation & purification | Nandrolone - analogs & derivatives | Antiprotozoal Agents - chemistry | Glucuronidase - chemistry | Antineoplastic Agents - chemistry | Testosterone Congeners - pharmacology | Antiprotozoal Agents - pharmacology | Cunninghamella - chemistry | Antiprotozoal Agents - isolation & purification | Animals | Nandrolone - pharmacology | Testosterone Congeners - metabolism | Mice | HeLa Cells | Saccharomycetales - metabolism | Nandrolone - chemistry | alpha-Glucosidases - chemistry | Anabolic steroids | Research | Metabolites | Transformation | Promastigotes | Toxicity | Colorectal cancer | Cytotoxicity | Biocatalysts | Cancer therapies | Tropical diseases | Microorganisms | Parasitic diseases | Cervical carcinoma | Enzymes | Glucosidase | Breast cancer | Cervix | Substrates | Biological activity | Chromatography | Chemistry | Carbonic anhydrase | Tyrosinase | Cervical cancer | Cancer | Steroids | Index Medicus
Journal Article
Talanta, ISSN 0039-9140, 08/2014, Volume 126, pp. 157 - 162
A molecularly imprinted polymer–matrix solid-phase dispersion methodology for simultaneous determination of five steroids in goat milk samples was proposed.... 
Goat milk | Matrix solid-phase dispersion | MEKC | Molecularly imprinted polymer | Steroids | CHEMISTRY, ANALYTICAL | BOVINE-MILK | TANDEM MASS-SPECTROMETRY | SYNTHETIC ESTROGENS | MEAT | PERFORMANCE LIQUID-CHROMATOGRAPHY | EXTRACTION | MICROEXTRACTION | URINE | CAPILLARY-ELECTROPHORESIS | SAMPLES | Milk - chemistry | Estradiol - isolation & purification | Goats | Ethinyl Estradiol - isolation & purification | Estrone - analysis | Progesterone - isolation & purification | Progesterone - chemistry | Acetonitriles - chemistry | Female | Molecular Structure | Buffers | Estrone - isolation & purification | Steroids - chemistry | Estradiol - analysis | Progesterone - analysis | Reproducibility of Results | Testosterone - isolation & purification | Borates - chemistry | Ethinyl Estradiol - analysis | Molecular Imprinting - methods | Pregnancy | Testosterone - chemistry | Estradiol - chemistry | Animals | Estrone - chemistry | Sodium Dodecyl Sulfate - chemistry | Solid Phase Extraction - methods | Testosterone - analysis | Ethinyl Estradiol - chemistry | Steroids - isolation & purification | Polymers - chemistry | Chromatography, Micellar Electrokinetic Capillary | Steroids - analysis | Testosterone | Surface active agents | Analysis | Ethinyl estradiol | Nitriles | Polymer industry | Sulfates | Polymers | Milk | Index Medicus | Dispersants | Imprinted polymers | Methodology | Extraction | Dispersions
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, pp. e43965 - e43965
Aldo-keto reductase 1C3 (AKR1C3) catalyses the NADPH dependent reduction of carbonyl groups in a number of important steroid and prostanoid molecules. The... 
POTENT INHIBITOR | CYCLOOXYGENASE INHIBITION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | PROSTAGLANDIN-F-SYNTHASE | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | MACROMOLECULAR CRYSTALLOGRAPHY | PRE-RECEPTOR REGULATION | CANCER CELL-MIGRATION | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Meclofenamic Acid - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Tolmetin - analogs & derivatives | Indomethacin - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Mefenamic Acid - chemistry | Naproxen - metabolism | Sulindac - metabolism | Ibuprofen - chemistry | Mefenamic Acid - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Hydroxyprostaglandin Dehydrogenases - chemistry | Tolmetin - metabolism | Sulindac - chemistry | Flurbiprofen - chemistry | Meclofenamic Acid - chemistry | Ibuprofen - metabolism | Naproxen - chemistry | Tolmetin - chemistry | Flufenamic Acid - metabolism | Aldo-Keto Reductase Family 1 Member C3 | Flufenamic Acid - chemistry | Indomethacin - chemistry | 3-Hydroxysteroid Dehydrogenases - chemistry | Flurbiprofen - metabolism | Oxidoreductases | Research | Nonsteroidal anti-inflammatory drugs | Structure | Properties | Drugs | Dehydrogenases | Drug development | Cancer therapies | Crystallography | Cell adhesion & migration | Proteins | Signal transduction | Distributed control systems | Naproxen | Sulindac | Ibuprofen | Inhibition | Catalysis | NADP | Flurbiprofen | Crystal structure | Carbonyls | Medical research | Enzymes | Antiinflammatory agents | Breast cancer | Inflammation | Aldo-keto reductase | Nonsteroidal antiinflammatory drugs | Carbonyl groups | Testosterone | Signaling | Acids | Mefenamic acid | Ligands | Indomethacin | Drug discovery | Prostate cancer | Prostate | Tumors | Cancer | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2007, Volume 282, Issue 35, pp. 25801 - 25816
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2013, Volume 13, Issue 12, pp. 1364 - 1384
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 2010, Volume 399, Issue 1, pp. 93 - 101
Journal Article