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1. Full Text Steroid secretion in healthy aging
by Fiacco, Serena and Walther, Andreas and Ehlert, Ulrike
Psychoneuroendocrinology, ISSN 0306-4530, 07/2019, Volume 105, pp. 64 - 78
Nowadays, people spend a considerable amount of their lives as older adults, but this longer lifespan is often accompanied by an increase in chronic conditions... 
Cognition | Mood | Healthy aging | Steroid hormones | Body composition | Sexual function | BONE-MINERAL DENSITY | PSYCHIATRY | NEUROSCIENCES | SALIVARY CORTISOL-LEVELS | ANDROGEN RECEPTOR POLYMORPHISM | LOW FREE TESTOSTERONE | SERUM DEHYDROEPIANDROSTERONE-SULFATE | ENDOCRINOLOGY & METABOLISM | POPULATION-BASED COHORT | BINDING GLOBULIN LEVELS | ENDOGENOUS SEX-HORMONES | QUALITY-OF-LIFE | VIGOROUS PHYSICAL-ACTIVITY | Corticosteroids | Exercise | Physiological aspects | Psychotherapy | Exercise for the aged | Aged | Hormones, Sex | Sexual disorders
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2. Full Text The adverse effects of aldrin and dieldrin on both myometrial contractions and the secretory functions of bovine ovaries and uterus in vitro
by Wrobel, Michał H and Grzeszczyk, Marlena and Mlynarczuk, Jaroslaw and Kotwica, Jan
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2015, Volume 285, Issue 1, pp. 23 - 31
Aldrin and dieldrin are chloroorganic insecticides which are recognised as endocrine disruptors. The aim of the study was to investigate their effect on the... 
Chloroorganic insecticides | Ovary | Cow | Contractions | Uterus | PROSTAGLANDIN SECRETION | METABOLITE DDE | ESTROGEN-RECEPTOR | SMOOTH-MUSCLE | SPONTANEOUS-ABORTION | RAT UTERUS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CORPUS-LUTEUM | OXYTOCIN RECEPTORS | ORGANOCHLORINE PESTICIDES | POLYCHLORINATED-BIPHENYLS | Dinoprostone - secretion | Gene Expression Regulation, Enzymologic - drug effects | Uterus - drug effects | Granulosa Cells - secretion | Dinoprost - secretion | Granulosa Cells - drug effects | Dose-Response Relationship, Drug | Time Factors | Cattle | Aldrin - toxicity | Luteal Cells - secretion | Female | Ovary - drug effects | Estradiol - secretion | Luteal Cells - drug effects | Progesterone - secretion | Testosterone - secretion | Tissue Culture Techniques | Cells, Cultured | Uterus - secretion | Endocrine Disruptors - toxicity | Uterine Contraction - drug effects | Animals | Ovary - secretion | Oxytocin - secretion | Dieldrin - toxicity | Insecticides - toxicity | Endocrine disruptors | Testosterone | Complications and side effects | Pituitary hormones | Analysis | Insecticides | Xenobiotics | Ovarian cancer | Index Medicus | ALDRIN | PROGESTERONE | TESTOSTERONE | ARACHIDONIC ACID | UTERUS | VIABILITY | ACTINOMYCIN | 60 APPLIED LIFE SCIENCES | SALTS | TETRAZOLIUM | XENOBIOTICS | CONTRACTION | PROSTAGLANDINS | DDT | IN VITRO | COWS | OVARIES | OXYTOCIN | DIELDRIN | PARTURITION | SECRETION
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3. Full Text Effects of individual polychlorinated naphthalene (PCN) components of Halowax 1051 and two defined, artificial PCN mixtures on AHR and CYP1A1 protein expression, steroid secretion and expression of enzymes involved in steroidogenesis (CYP17, 17β-HSD and CYP19) in porcine ovarian follicles
by Barć, Justyna and Gregoraszczuk, Ewa Łucja
Toxicology, ISSN 0300-483X, 2014, Volume 322, pp. 14 - 22
Abstract In this study we tried to answer a question which component of Halowax 1051 is responsible for, observed in previously published study, androgenic... 
Emergency | CYP1A1 | Ovary | PCN | Steroidogenesis | AHR | Halowax 1051 | RELATIVE POTENCIES | ACTIVATION | GRANULOSA-CELLS | DOWN-REGULATION | RECEPTOR | INDUCTION | METABOLITE P,P'-DDE | CHLORONAPHTHALENES | INHIBITION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CONSUMPTION | Naphthalenes - chemistry | Receptors, Aryl Hydrocarbon - biosynthesis | Gene Expression Regulation, Enzymologic - drug effects | Hydrocarbons, Chlorinated - chemistry | Hydrocarbons, Chlorinated - toxicity | Aromatase - biosynthesis | Blotting, Western | Estrous Cycle - drug effects | Ovarian Follicle - drug effects | 17-Hydroxysteroid Dehydrogenases - biosynthesis | Animals | Swine | Steroids - metabolism | Female | Naphthalenes - toxicity | Cytochrome P-450 CYP1A1 - biosynthesis | Ovarian Follicle - metabolism | Steroid 17-alpha-Hydroxylase - biosynthesis | Steroids - biosynthesis | Physiological aspects | Testosterone | Analysis | Estrogen | Cytochrome P-450 | Index Medicus | Proteins | Enzymes | Sex hormones | Naphthalene | Congeners | Exposure | Secretions
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4. Full Text Testosterone Reduces Neuronal Secretion of Alzheimer's β -Amyloid Peptides
by Gunnar K. Gouras and Huaxi Xu and Rachel S. Gross and Jeffrey P. Greenfield and Bing Hai and Rong Wang and Paul Greengard
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2000, Volume 97, Issue 3, pp. 1202 - 1205
Alzheimer's disease (AD) is characterized by the age-related deposition of β -amyloid(Aβ) 40/42 peptide aggregates in vulnerable brain regions. Multiple levels... 
Testosterone | Biological Sciences | Secretion | Neurons | Estrogens | Men | Antibodies | Postmenopause | Hormones | Cholesterols | Steroids | CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | DISEASE | ESTROGEN | RISK | GENERATION | PRECURSOR PROTEIN | BRAIN | AGE | Amino Acid Sequence | Peptide Fragments - metabolism | Corticosterone - pharmacology | Humans | Molecular Sequence Data | Rats | Male | Testosterone - pharmacology | Rats, Sprague-Dawley | Animals | Alzheimer Disease - prevention & control | Secretory Rate - drug effects | Alzheimer Disease - metabolism | Amyloid beta-Protein Precursor - metabolism | Cholesterol - pharmacology | Female | Mice | Neurons - metabolism | Estradiol - pharmacology
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5. Emerging role of testosterone in pancreatic β cell function and insulin secretion
by Xu, Weiwei and Morford, Jamie and Mauvais-Jarvis, Franck
Journal of Endocrinology, ISSN 0022-0795, 03/2019, Volume 240, Issue 3, pp. R97 - R105
One of the most sexually dimorphic aspects of metabolic regulation is the bidirectional modulation of glucose homeostasis by testosterone in male and females.... 
Islet cells | Testosterone | Diabetes | Sex dimorphism | Androgen receptor | POLYCYSTIC-OVARY-SYNDROME | PROSTATE | testosterone | IMPAIRED GLUCOSE-TOLERANCE | RECEPTOR | ANDROGEN-DEPRIVATION THERAPY | COMPLEMENTARY-DNA | sex dimorphism | OBESITY | androgen receptor | islet cells | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | REPLACEMENT THERAPY | GENE-EXPRESSION | diabetes
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6. Full Text Proinflammatory Cytokine Infusion Attenuates LH's Feedforward on Testosterone Secretion: Modulation by Age
by Veldhuis, Johannes and Yang, Rebecca and Roelfsema, Ferdinand and Takahashi, Paul
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 02/2016, Volume 101, Issue 2, pp. 539 - 549
Context: In the experimental animal, inflammatory signals quench LH's feedforward drive of testosterone (T) secretion and appear to impair GnRH-LH output. The... 
RECOMBINANT HUMAN INTERLEUKIN-6 | ALDESLEUKIN THERAPY | PULSE | DISEASE | ENDOCRINOLOGY & METABOLISM | OLDER MEN | GNRH | PITUITARY-ADRENAL AXIS | HEALTHY-MEN | HYPOGONADISM | LUTEINIZING-HORMONE | Prospective Studies | Testosterone - secretion | Double-Blind Method | Interleukin-2 - adverse effects | Humans | Middle Aged | Risk Factors | Male | Cross-Over Studies | Dose-Response Relationship, Drug | Young Adult | Aging - physiology | Interleukin-2 - administration & dosage | Interleukin-2 - pharmacology | Feedback, Physiological - drug effects | Aged | Cytokines - pharmacology | Luteinizing Hormone - secretion | Original
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7. Full Text Gonadotropins in the Russian sturgeon: Their role in steroid secretion and the effect of hormonal treatment on their secretion
by Yom-Din, Svetlana and Hollander-Cohen, Lian and Aizen, Joseph and Boehm, Benjamin and Shpilman, Michal and Golan, Matan and Hurvitz, Avshalom and Degani, Gad and Levavi-Sivan, Berta
PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, p. e0162344
In the reproduction process of male and female fish, pituitary derived gonadotropins (GTHs) play a key role. To be able to specifically investigate certain... 
RAINBOW-TROUT | ALPHA-SUBUNIT | LINKED-IMMUNOSORBENT-ASSAY | MULTIDISCIPLINARY SCIENCES | PITUITARY-GONADAL AXIS | ACIPENSER-GUELDENSTAEDTII | FOLLICLE-STIMULATING-HORMONE | HUMAN CHORIONIC-GONADOTROPIN | REPRODUCTIVE-CYCLE | TROUT ONCORHYNCHUS-MYKISS | LUTEINIZING-HORMONE | Protein Subunits | Gonadotropin-Releasing Hormone - pharmacology | Male | Testosterone - analogs & derivatives | Testosterone - pharmacology | Gonadotropin-Releasing Hormone - analogs & derivatives | Steroids - physiology | Testis - drug effects | Follicle Stimulating Hormone - pharmacology | Testosterone - metabolism | Ovarian Follicle - drug effects | Ovarian Follicle - physiology | Female | Luteinizing Hormone - pharmacology | Fishes - physiology | Follicle Stimulating Hormone - chemistry | Estradiol - metabolism | Enzyme-Linked Immunosorbent Assay | Gonadotropins, Pituitary - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - pharmacology | Testis - physiology | Animals | Gonadotropins, Pituitary - physiology | Luteinizing Hormone - chemistry | Pituitary Gland - drug effects | Pituitary Gland - physiology | Testosterone | Follicle-stimulating hormone | Fishes | Glycoproteins | Hormones | Contamination | Enzyme-linked immunosorbent assay | Yeast | Antibodies | Biology | Biochemistry | Pichia pastoris | Males | Follicles | Estradiol | Developmental stages | Luteinizing hormone | Fish | Physiology | Localization | Food | Recombinant | Bass | Puberty | Immunoglobulins | Dopamine | Carp | Pituitary hormones | Secretion | Trout | Animal sciences | Sturgeon | Tilapia | Gonadotropins | Pituitary (anterior) | Gene expression | Water temperature | Biological activity | Sex hormones | Fish reproduction | Pituitary | Gonadotropin-releasing hormone | Feeds | Females | Gonads | Three dimensional models | Endocrinology | Aquaculture | Steroids
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8. Full Text Development of gonadotropin-releasing hormone secretion and pituitary response
by Glanowska, Katarzyna M and Burger, Laura L and Moenter, Suzanne M
Journal of Neuroscience, ISSN 0270-6474, 11/2014, Volume 34, Issue 45, pp. 15060 - 15069
Acquisition of a mature pattern of gonadotropin-releasing hormone (GnRH) secretion from the CNSis a hallmark of the pubertal process. Little is known about... 
Cyclic voltammetry | Puberty | Testosterone | Gonadotropin releasing hormone | Gonadotropin inhibitory hormone | testosterone | RHESUS-MONKEY | GNRH NEURONS | NEUROSCIENCES | LUTEINIZING-HORMONE | MESSENGER-RIBONUCLEIC-ACID | cyclic voltammetry | FEMALE RATS | ADULT MALE-MICE | gonadotropin inhibitory hormone | TESTOSTERONE SECRETION | GENE-EXPRESSION | FOLLICLE-STIMULATING-HORMONE | puberty | REPRODUCTIVE AXIS | gonadotropin releasing hormone | Gonadotropin-Releasing Hormone - secretion | Pituitary Hormone Release Inhibiting Hormones - pharmacology | Luteinizing Hormone - genetics | Gonadotropin-Releasing Hormone - genetics | RNA, Messenger - genetics | Cells, Cultured | Pituitary Gland - growth & development | Male | Pituitary Gland - secretion | Luteinizing Hormone - metabolism | Kisspeptins - metabolism | RNA, Messenger - metabolism | Testosterone - pharmacology | Pituitary Gland - embryology | Kisspeptins - genetics | Animals | Gonadotropin-Releasing Hormone - metabolism | Mice | Pituitary Gland - drug effects | Sexual Maturation
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9. Full Text A glance at…nutritional antioxidants and testosterone secretion
by Glade, Michael J., Ph.D and Smith, Kyl, D.C and Meguid, Michael M., M.D., Ph.D
Nutrition, ISSN 0899-9007, 2015, Volume 31, Issue 10, pp. 1295 - 1298
Gastroenterology and Hepatology | Antioxidants | Oxidative stress | Low testosterone | Phosphatidylserine | Leydig cells | VITAMIN-E | ALPHA-TOCOPHEROL | DIETARY-INTAKE | ASCORBIC-ACID | AGING ALTERS | NUTRITION & DIETETICS | LIPOIC ACID | POLYCHLORINATED BIPHENYL AROCLOR-1254 | INDUCED OXIDATIVE STRESS | PROTECTIVE ROLE | MOLECULAR-MECHANISMS | Animals | Testosterone - secretion | Humans | Antioxidants - administration & dosage | Rats | Male | Leydig Cells - drug effects | Oxidative Stress - drug effects | Dietary Supplements
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10. HIGH DOSES OF PROLACTIN INHIBIT TESTOSTERONE SECRETION IN RAT LEYDIG CELLS
by Raji, Yinusa
HIGH DOSES OF PROLACTIN INHIBIT TESTOSTERONE SECRETION IN RAT LEYDIG CELLS, 12/1999
The effect of prolactin on dispersed rat Leydig cells was investigated. Leydig cells from adult rat testes of proven fertility were isolated via collagenase... 
Prolactin, Testosterone, Leydig Cells
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11. Full Text Effects of PCB 126 and PCB 153 on secretion of steroid hormones and mRNA expression of steroidogenic genes (STAR, HSD3B, CYP19A1) and estrogen receptors (ERα, ERβ) in prehierarchical chicken ovarian follicles
by Sechman, Andrzej and Batoryna, Marta and Antos, Piotr A and Hrabia, Anna
Toxicology Letters, ISSN 0378-4274, 12/2016, Volume 264, pp. 29 - 37
The objective of this study was to assess the effects of dioxin-like PCB 126 and non-dioxin-like PCB 153 on basal and ovine LH (oLH)-stimulated testosterone... 
Chicken ovary | Estrogen receptors | Steroidogenesis | PCB 126 | PCB 153 | ENDOCRINE-DISRUPTING CHEMICALS | POLYCHLORINATED-BIPHENYLS PCBS | GRANULOSA-CELLS | DEVELOPMENTAL COMPETENCE | PREOVULATORY FOLLICLES | TRANSLOCATOR 1 ARNT1 | PROGESTERONE PRODUCTION | TOXICOLOGY | HUMAN FOLLICULAR-FLUID | IN-VITRO EXPOSURE | LUTEAL CELLS | Gene Expression Regulation, Enzymologic - drug effects | Progesterone Reductase - metabolism | Ovarian Follicle - growth & development | RNA, Messenger - genetics | Follicular Phase - drug effects | Aromatase - metabolism | Testosterone - metabolism | Ovarian Follicle - drug effects | Animals | Polychlorinated Biphenyls - toxicity | Chickens | Estrogen Receptor beta - biosynthesis | Steroids - metabolism | Female | Estrogen Receptor alpha - biosynthesis | Ovarian Follicle - metabolism | Physiological aspects | Messenger RNA | Genes | Estrogen | Cytochrome P-450 | Testosterone | Analysis | Dioxin | Phenols | Genetic research | Gene expression | Estradiol | Index Medicus
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12. Full Text In vitro effect of 4-nonylphenol on human chorionic gonadotropin (hCG) stimulated hormone secretion, cell viability and reactive oxygen species generation in mice Leydig cells
by Jambor, Tomáš and Tvrdá, Eva and Tušimová, Eva and Kováčik, Anton and Bistáková, Jana and Forgács, Zsolt and Lukáč, Norbert
Environmental Pollution, ISSN 0269-7491, 03/2017, Volume 222, pp. 219 - 225
Nonylphenol is considered an endocrine disruptor and has been reported to affect male reproductive functions. In our study, we evaluated the effects of... 
Reactive oxygen species | Hormones | Viability | 4-nonylphenol | Human chorionic gonadotropin | MITOCHONDRIA | RATS | PROLIFERATION | MICROSOMAL CYTOCHROME-P-450 ENZYMES | MEDIATED DAMAGE | NONYLPHENOL | ENVIRONMENTAL SCIENCES | CULTURES | Leydig Cells - physiology | Cell Survival - drug effects | Reactive Oxygen Species - metabolism | Enzyme-Linked Immunosorbent Assay | Humans | Male | Leydig Cells - drug effects | Phenols - metabolism | Androstenedione - metabolism | Chorionic Gonadotropin - metabolism | Mice, Inbred ICR | Testosterone - metabolism | Animals | Endocrine Disruptors - pharmacology | Mice | Phenols - pharmacology | Testosterone | Enzymes | Dehydroepiandrosterone | Chorionic gonadotropin | Physiological aspects | Phenols | Agriculture | Glycoproteins
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