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Cancer Letters, ISSN 0304-3835, 2010, Volume 332, Issue 2, pp. 295 - 303
Journal Article
Drugs, ISSN 0012-6667, 11/2015, Volume 75, Issue 17, pp. 1993 - 2016
Through years of evolutionary selection pressures, organisms have developed potent toxins that coincidentally have marked antineoplastic activity. These... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | IMMUNOTOXIN RFB4(DSFV)-PE38 BL22 | PEGYLATED LIPOSOMAL DOXORUBICIN | EPOTHILONE-B ANALOG | DRUG-RESISTANT PHENOTYPE | GEMTUZUMAB OZOGAMICIN | PHASE-I TRIAL | METASTATIC BREAST-CANCER | ERIBULIN MESYLATE E7389 | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ANTI-MESOTHELIN IMMUNOTOXIN | CHRONIC MYELOID-LEUKEMIA | Dioxoles - therapeutic use | Diphtheria Toxin - pharmacology | Recombinant Fusion Proteins - pharmacology | Furans - pharmacology | Humans | Recombinant Fusion Proteins - therapeutic use | Interleukin-2 - therapeutic use | Epothilones - pharmacology | Drug Discovery - methods | Antineoplastic Agents - therapeutic use | Biological Products - pharmacology | Epothilones - therapeutic use | Harringtonines - therapeutic use | Furans - therapeutic use | TOR Serine-Threonine Kinases - antagonists & inhibitors | Diphtheria Toxin - therapeutic use | Immunoconjugates - pharmacology | Cytochalasins - pharmacology | Dioxoles - pharmacology | Immunoconjugates - therapeutic use | Antineoplastic Agents - pharmacology | Ketones - therapeutic use | Cytochalasins - therapeutic use | Biological Products - therapeutic use | Ketones - pharmacology | Tetrahydroisoquinolines - pharmacology | Tetrahydroisoquinolines - therapeutic use | Withanolides - pharmacology | Harringtonines - pharmacology | Interleukin-2 - pharmacology | Withanolides - therapeutic use | Antimitotic agents | Care and treatment | Chemotherapy | Usage | Clinical trials | Dosage and administration | Diagnosis | Antineoplastic agents | Cancer | Index Medicus | Review
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2017, Volume 18, Issue 9, p. 1959
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2007, Volume 30, Issue 1, pp. 54 - 58
Solifenacin succinate [YM905; (3R)-1-azabicyclo[2.2.2]oct-3-yl(1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate monosuccinate] is a new muscarinic... 
bladder capacity | solifenacin | urinary bladder | muscarinic receptor | Muscarinic receptor | Solifenacin | Urinary bladder | Bladder capacity | OVERACTIVE BLADDER SYNDROME | M-3 MUSCARINIC RECEPTORS | RAT | URINARY-BLADDER | DETRUSOR OVERACTIVITY | TOLTERODINE | SALIVARY-GLAND | IN-VITRO | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MICE | Cricetulus | Rats, Wistar | Solifenacin Succinate | Benzofurans - pharmacology | Male | Phenylpropanolamine - pharmacology | Receptors, Muscarinic - metabolism | Muscarinic Antagonists - therapeutic use | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Mandelic Acids - pharmacology | Muscle, Smooth - drug effects | Urinary Bladder, Overactive - drug therapy | Quinuclidines - therapeutic use | Receptors, Muscarinic - drug effects | Transfection | Muscarinic Antagonists - pharmacology | Tolterodine Tartrate | Urination - drug effects | Benzilates - pharmacology | Cholinergic Agonists - pharmacology | Cresols - pharmacology | CHO Cells | Muscarinic Antagonists - metabolism | Binding, Competitive | Tetrahydroisoquinolines - pharmacology | Cricetinae | Quinuclidines - pharmacology | Rats | Atropine - pharmacology | Tetrahydroisoquinolines - therapeutic use | Rats, Sprague-Dawley | Carbachol - pharmacology | Animals | Muscle Contraction - drug effects | Tetrahydroisoquinolines - metabolism | N-Methylscopolamine - metabolism | Urinary Bladder - drug effects | Benzhydryl Compounds - pharmacology | In Vitro Techniques | Quinuclidines - metabolism
Journal Article
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 2/2007, Volume 59, Issue 2, pp. 157 - 164
The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs... 
Biomedicine | Chemosensitivity | Oncology | Cancer Research | Confocal microscopy | Human glioblastoma cells | Pharmacology/Toxicology | Kinesin inhibitors | Monastrol analogues | monastrol analogues | PROTEIN | P-GLYCOPROTEIN | PACLITAXEL | kinesin inhibitors | POTENT | ONCOLOGY | confocal microscopy | IN-VIVO | BIOLOGICAL EVALUATION | human glioblastoma cells | PHARMACOLOGY & PHARMACY | chemosensitivity | MULTIDRUG-RESISTANCE | BRAIN | Fluoresceins - pharmacology | Cysteine - analogs & derivatives | Flow Cytometry - methods | Paclitaxel - pharmacology | Tubulin Modulators - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Pyrimidines - chemistry | Dose-Response Relationship, Drug | Tubulin - metabolism | Spindle Apparatus - metabolism | Time Factors | Cysteine - pharmacology | Rotenone - pharmacology | Glioblastoma - metabolism | Molecular Structure | Kinesin - antagonists & inhibitors | Quinazolines - chemistry | Insecticides - pharmacology | Cell Survival - drug effects | Tetrahydroisoquinolines - pharmacology | Thiones - chemistry | Pyrimidines - pharmacology | Kinesin - metabolism | Acridines - pharmacology | Glioblastoma - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Spindle Apparatus - drug effects | Vinblastine - pharmacology | Thiones - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Quinazolines - pharmacology | Brain tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0158808
Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na+). Using radioligand competition binding assays, we have... 
Nitriles - pharmacology | Humans | Receptors, Dopamine D3 - metabolism | Piperazines - metabolism | Piperazines - chemistry | Sodium - metabolism | Receptors, Dopamine D2 - metabolism | Biphenyl Compounds - metabolism | Spodoptera | Receptors, Dopamine D3 - genetics | Indoles - metabolism | Sf9 Cells | Biphenyl Compounds - pharmacology | Piperidines - pharmacology | Tetrahydroisoquinolines - chemistry | Dopamine Antagonists - metabolism | Indoles - pharmacology | Molecular Structure | Biphenyl Compounds - chemistry | Radioligand Assay | Dopamine Agonists - metabolism | Binding, Competitive | Indans - chemistry | Dopamine Agonists - pharmacology | Nitriles - metabolism | Tetrahydroisoquinolines - pharmacology | Piperidines - chemistry | Piperidines - metabolism | Receptors, Dopamine D2 - agonists | Indans - metabolism | Ions - metabolism | Piperazines - pharmacology | Receptors, Dopamine D2 - genetics | Receptors, Dopamine D3 - agonists | Animals | Dopamine Antagonists - pharmacology | Tetrahydroisoquinolines - metabolism | Dopamine D2 Receptor Antagonists - metabolism | Nitriles - chemistry | Cell Line, Tumor | Dopamine D2 Receptor Antagonists - pharmacology | Ligands | Mutation | Indoles - chemistry | Indans - pharmacology | G protein-coupled receptors | Mental disorders | Infections | Antagonists | Assaying | Proteins | Psychosis | Psychotropic drugs | Signal transduction | Receptors | Drug therapy | Buffers | Dopamine D2 receptors | Binding | Dopamine | Therapeutic applications | Cloning | Dopamine D3 receptors | Ions | Clozapine | Spiperone | Sensitivity | Sodium | Ionic strength | Pharmacy | Inverse agonists | Affinity | Cations
Journal Article