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Experimental cell research, ISSN 0014-4827, 2010, Volume 316, Issue 19, pp. 3109 - 3123
Mesenchymal stromal cells (MSCs) have important immunosuppressive properties, but the mechanisms and soluble factors involved in these effects remain unclear... 
T lymphocytes | Mesenchymal stromal cells | Prostaglandin E2 | Immunosuppressive properties | Dendritic cells | VERSUS-HOST-DISEASE | LYMPHOCYTE-PROLIFERATION | TRANSPLANTATION | CELL BIOLOGY | THERAPY | ONCOLOGY | ADULT STEM-CELLS | ANTIGEN-PRESENTING CELLS | DIFFERENTIATION | T-CELLS | INHIBIT | Dinoprostone - secretion | Mitogens - pharmacology | Coculture Techniques | Dendritic Cells - immunology | Humans | Adipose Tissue - cytology | Th2 Cells - immunology | RNA, Messenger - metabolism | Th1 Cells - immunology | Th2 Cells - drug effects | Mesenchymal Stromal Cells - immunology | Mesenchymal Stromal Cells - cytology | Immune Tolerance - immunology | Phytohemagglutinins - pharmacology | Stromal Cells - drug effects | Dendritic Cells - drug effects | Cytokines - genetics | Immune Tolerance - drug effects | Mesenchymal Stromal Cells - drug effects | Th1 Cells - drug effects | Bone Marrow Cells - cytology | RNA, Messenger - genetics | Cytokines - secretion | Immunophenotyping | Stromal Cells - immunology | Th2 Cells - cytology | Indomethacin - pharmacology | Dinoprostone - metabolism | Gene Expression Regulation - drug effects | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Cell Proliferation - drug effects | Dendritic Cells - cytology | Th1 Cells - cytology | Stromal Cells - cytology | Indomethacin | T cells | Prostaglandins E | Analysis | Stem cells | Bone marrow | Cell culture | Immunology | Cellular biology | Cytokines | Index Medicus | DENDRITES | TRANSCRIPTION FACTORS | LYMPHOKINES | PROSTAGLANDINS | INFLAMMATION | BONE MARROW | CELL PROLIFERATION | SECRETION | 60 APPLIED LIFE SCIENCES | ADIPOSE TISSUE | LYMPHOCYTES
Journal Article
Journal of the American Heart Association, ISSN 2047-9980, 09/2016, Volume 5, Issue 9, p. n/a
.... Naïve T cells were cocultured with pretreated DCs. The effects of statin were studied... 
atherosclerosis | dendritic cells | statin | immune system | microRNA | oxidized low‐density lipoprotein | T cells | MicroRNA | Dendritic cells | Oxidized low-density lipoprotein | Atherosclerosis | Statin | Immune system | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | INDUCTION | CANCER | ARTERIOSCLEROSIS | HEAT-SHOCK-PROTEIN | THERAPY | INHIBITION | INFLAMMATION | oxidized low-density lipoprotein | ASSOCIATION | LYMPHOCYTES | Interleukin-1beta - drug effects | Extracellular Signal-Regulated MAP Kinases - drug effects | Atorvastatin Calcium - pharmacology | Dendritic Cells - immunology | Humans | Interferon-gamma - drug effects | Interleukin-17 - immunology | Chaperonin 60 - immunology | Extracellular Signal-Regulated MAP Kinases - metabolism | Simvastatin - pharmacology | Th1 Cells - immunology | Mitochondrial Proteins - drug effects | Endarterectomy, Carotid | Lymphocyte Activation - immunology | Th17 Cells - drug effects | HSP90 Heat-Shock Proteins - immunology | T-Lymphocytes - drug effects | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Tumor Necrosis Factor-alpha - immunology | Dendritic Cells - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Real-Time Polymerase Chain Reaction | T-Box Domain Proteins - drug effects | Th1 Cells - drug effects | HSP90 Heat-Shock Proteins - drug effects | Interleukin-1beta - immunology | Lipoproteins, LDL - pharmacology | HSP27 Heat-Shock Proteins - immunology | Plaque, Atherosclerotic - immunology | MicroRNAs - immunology | Reverse Transcriptase Polymerase Chain Reaction | HSP27 Heat-Shock Proteins - drug effects | T-Box Domain Proteins - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Tumor Necrosis Factor-alpha - drug effects | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-6 - immunology | MicroRNAs - drug effects | Th17 Cells - immunology | T-Lymphocytes - immunology | Chaperonin 60 - drug effects | Mitochondrial Proteins - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - drug effects | Proto-Oncogene Proteins c-akt - drug effects
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2010, Volume 207, Issue 6, pp. 1247 - 1260
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 554, Issue 7693, pp. 538 - 543
...(1,2). Instead, particular features of the tumour microenvironment, such as lack of T-cell infiltration(3... 
STEM-CELLS | DISRUPTION | GENE | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | LEADS | MICE | GROWTH-FACTOR | EXPRESSION | PROGRESSION | TRANSPLANTATION | Intestines - drug effects | Colonic Neoplasms - genetics | Intestinal Mucosa - metabolism | Colonic Neoplasms - drug therapy | Humans | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Stem Cells - metabolism | Th1 Cells - immunology | T-Lymphocytes, Cytotoxic - drug effects | Neoplasm Metastasis - drug therapy | Neoplasm Metastasis - immunology | Colonic Neoplasms - immunology | Immunotherapy | Transforming Growth Factor beta - antagonists & inhibitors | Female | Liver Neoplasms - secondary | Disease Models, Animal | T-Lymphocytes, Cytotoxic - immunology | Transforming Growth Factor beta - immunology | Tumor Microenvironment - drug effects | Th1 Cells - drug effects | Intestines - pathology | Liver Neoplasms - drug therapy | Liver Neoplasms - immunology | Drug Synergism | Tumor Microenvironment - immunology | Neoplasm Metastasis - genetics | Animals | Cell Differentiation - drug effects | Neoplasm Metastasis - pathology | Colonic Neoplasms - pathology | Alleles | Immune Evasion - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Mice | Mutation | T-Lymphocytes, Cytotoxic - cytology | PD-1 protein | Liver | Colorectal carcinoma | Colorectal cancer | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Metastasis | Metastases | Colon cancer | Intestine | Lymphocytes | Genetic analysis | Fibroblasts | Colon | Inhibition | Growth factors | Phenotypes | Data analysis | Liver diseases | Microsatellites | Organs | Gene expression | Patients | Signaling | Immune checkpoint | PD-L1 protein | Stem cells | Tumors | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e31296
...(+) T cells is regulated transcriptionally and made from new mRNA following antigen recognition... 
POSTTRANSCRIPTIONAL REGULATION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | THYMIC EPITHELIAL-CELLS | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | EFFECTOR FUNCTION | CD40-CD40 LIGAND | SECRETORY LYSOSOMES | TRANSGENIC MICE | CD8-Positive T-Lymphocytes - cytology | Inflammation - pathology | T-Lymphocytes, Regulatory - metabolism | Natural Killer T-Cells - drug effects | Thymocytes - metabolism | Protein Transport - drug effects | Th2 Cells - drug effects | Side-Population Cells - drug effects | T-Lymphocytes, Helper-Inducer - drug effects | Th1 Cells - metabolism | Interleukin-4 - pharmacology | Th17 Cells - drug effects | CD40 Ligand - metabolism | Th17 Cells - metabolism | Natural Killer T-Cells - metabolism | Side-Population Cells - metabolism | T-Lymphocytes, Helper-Inducer - cytology | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Th17 Cells - cytology | Th1 Cells - drug effects | Intracellular Space - drug effects | T-Lymphocytes, Helper-Inducer - metabolism | Mice, Inbred C57BL | Natural Killer T-Cells - cytology | Th2 Cells - cytology | Inflammation - immunology | Down-Regulation - drug effects | Side-Population Cells - cytology | Th2 Cells - metabolism | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Intracellular Space - metabolism | Staining and Labeling | Antigens - immunology | Thymocytes - cytology | Thymocytes - drug effects | Mice | Th1 Cells - cytology | Transcription | Helper cells | Central nervous system | Science | Effector cells | Critical care | Cytotoxicity | Viruses | Lipids | Activation | Lymphocytes T | CD40L protein | Invariants | Respiratory tract | Hepatitis | Cell activation | Immunology | Lymphocytes | Rodents | Natural killer cells | Encephalitis | Antigens | Antigen presentation | Immunological memory | Lymphatic system | Memory cells | Immunoglobulins | Immune response | Cytokines | Dendritic cells | T cell receptors | Experimental allergic encephalomyelitis | Asthma | CD4 antigen | Computer memory | Thymocytes | Lymphocytes B | Antigen-presenting cells | Influenza | Apoptosis
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2017, Volume 198, Issue 8, pp. 3069 - 3080
Dimethyl fumarate (DMF; trade name Tecfidera) is an oral formulation of the fumaric acid ester that is Food and Drug Administration approved for treatment of relapsing-remitting multiple sclerosis... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | OXIDATIVE STRESS | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | PLACEBO-CONTROLLED PHASE-3 | SUBSETS | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | BLOOD-BRAIN-BARRIER | ORAL BG-12 | ACID ESTERS | TH17 CELLS | T-Lymphocyte Subsets - immunology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Th2 Cells - immunology | Immunologic Memory - drug effects | Th1 Cells - immunology | Th2 Cells - drug effects | Lymphocyte Activation - immunology | Th17 Cells - drug effects | Flow Cytometry | T-Lymphocyte Subsets - drug effects | Adult | Female | Immunologic Memory - immunology | Cell Survival - drug effects | Th1 Cells - drug effects | Multiple Sclerosis, Relapsing-Remitting - immunology | Cross-Sectional Studies | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Immunophenotyping | Dimethyl Fumarate - therapeutic use | Lymphocyte Activation - drug effects | Th17 Cells - immunology | Cell Proliferation - drug effects | Longitudinal Studies | Dimethyl | CC chemokine receptors | Flow cytometry | Reactive oxygen species | Multiple sclerosis | CD8 antigen | Helper cells | Effector cells | Activation | Lymphocytes T | Leukoencephalopathy | Progressive multifocal leukoencephalopathy | Interleukin 4 | Cell activation | Lymphocytes | Longitudinal studies | Immunological memory | Memory cells | Cell survival | CCR7 protein | Inflammation | CXCR3 protein | FDA approval | Patients | Interleukin 17 | CCR6 protein | CD4 antigen | Cytometry | Side effects | Fumaric acid | Correlation analysis | γ-Interferon | Interferon | Apoptosis | RRMS | Effector memory T cells | T helper cells | Dimethyl Fumarate | PBMC
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 4, p. e0154564
.... However, the underlying mechanism is largely unknown. In this research, we investigate the anti-inflammatory effects of AZD8055, a potent mTOR inhibitor, on T cell response in dextran sulfate sodium (DSS... 
B-CELLS | INTESTINAL INFLAMMATION | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | DENDRITIC CELLS | GM-CSF | MULTIDISCIPLINARY SCIENCES | IN-VIVO | KINASE INHIBITOR | ANTITUMOR-ACTIVITY | TH17 CELLS | T-Lymphocyte Subsets - immunology | Th1 Cells - pathology | CD8-Positive T-Lymphocytes - pathology | Colon - drug effects | Colitis - pathology | Colon - immunology | Male | CD4-Positive T-Lymphocytes - pathology | Th1 Cells - immunology | T-Lymphocytes, Regulatory - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Th17 Cells - drug effects | T-Lymphocyte Subsets - drug effects | Inflammation Mediators - metabolism | Disease Models, Animal | Th17 Cells - pathology | Th1 Cells - drug effects | Colon - pathology | Mice, Inbred C57BL | Morpholines - pharmacology | Dextran Sulfate - toxicity | Colitis - etiology | T-Lymphocytes, Regulatory - drug effects | Animals | T-Lymphocyte Subsets - pathology | Cell Differentiation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Th17 Cells - immunology | Cell Proliferation - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Colitis - prevention & control | CD4-Positive T-Lymphocytes - drug effects | Dextran | Prevention | Dosage and administration | Interferon | Inflammation | Research | Colitis | T cells | CD8 antigen | Body weight | Body weight loss | Proteins | Cell growth | Surgery | Peripheral blood | Dextran sulfate | Bone marrow | Spleen | Cytokines | Lamina propria | Rapamycin | Gene expression | Studies | Inflammatory bowel disease | Hospitals | Sodium | Interleukin 10 | Cell proliferation | Animal models | Phosphorylation | Inflammatory bowel diseases | Leukemia | Interleukin | Helper cells | Lymphocytes T | Kinases | Sulfates | Autophagy | Lymph nodes | Interleukin 6 | Ethics | Granulocytes | Lymphocytes | Intestine | Rodents | Gastroenterology | Colon | Dendritic cells | Histology | CD4 antigen | Medicine | Sulfate | Laboratory animals
Journal Article
Autophagy, ISSN 1554-8635, 2014, Volume 8, Issue 9, pp. 1357 - 1370
Emerging evidence points to an important role of autophagy in the immune response mediated by dendritic cells (DC... 
vaccine | autophagy | dendritic cells | Mycobacterium tuberculosis | BCG | RD1 region | ESX1/type VII secretion system | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Dendritic cells | Vaccine | Autophagy | Rd1 region | SYSTEM | MACROPHAGES | VIRULENCE | ESAT-6 SECRETION | CELL BIOLOGY | ADAPTIVE IMMUNITY | PHAGOSOME | IMMUNOGENICITY | GENE-EXPRESSION | T-CELLS | Biomarkers - metabolism | Th1 Cells - drug effects | Humans | Phagosomes - metabolism | Cells, Cultured | Mycobacterium tuberculosis - ultrastructure | Dendritic Cells - pathology | Tuberculosis - microbiology | Th1 Cells - immunology | Mycobacterium tuberculosis - drug effects | Sirolimus - pharmacology | Autophagy - drug effects | Tuberculosis - immunology | Mycobacterium bovis - drug effects | Bacterial Secretion Systems - drug effects | Cell Differentiation - drug effects | Dendritic Cells - ultrastructure | Mycobacterium tuberculosis - physiology | Dendritic Cells - microbiology | Dendritic Cells - drug effects | Phagosomes - ultrastructure | Mycobacterium bovis - physiology | Phagosomes - drug effects | Tuberculosis - pathology | Dendritic Cells | Bacterial Secretion Systems | Sirolimus | Mycobacterium bovis | Phagosomes | Life Sciences | Tuberculosis | Th1 Cells | Biomarkers | Cell Differentiation | ESX1 | Basic Research Paper | type VII secretion system
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2016, Volume 291, Issue 3, pp. 1123 - 1136
... in antigen-presenting cells such as macrophages and dendritic cells when co-stimulated with the TLR4-agonist adjuvant monophosphoryl lipid... 
ADAPTIVE IMMUNITY | MONOPHOSPHORYL-LIPID-A | HEALTHY ADULT VOLUNTEERS | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NLRP3 INFLAMMASOME | T-CELL | ISCOMATRIX ADJUVANT | PARTICULATE VACCINE ADJUVANTS | QUILLAJA-SAPONARIA MOLINA | NALP3 INFLAMMASOME | HIV Envelope Protein gp120 - agonists | Lipid A - agonists | Adjuvants, Immunologic - analysis | Adjuvants, Immunologic - pharmacology | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Lipid A - analogs & derivatives | AIDS Vaccines - immunology | AIDS Vaccines - agonists | Th2 Cells - immunology | Th1 Cells - immunology | GTP-Binding Proteins - genetics | Th2 Cells - drug effects | Saponins - chemistry | HIV Envelope Protein gp120 - immunology | Th1 Cells - metabolism | Immunoglobulin G - biosynthesis | Inflammasomes - drug effects | Adjuvants, Immunologic - chemistry | Bone Marrow Cells - immunology | Bone Marrow Cells - drug effects | Dendritic Cells - drug effects | Immunoglobulin G - analysis | Macrophages - immunology | Cell Survival - drug effects | Th1 Cells - drug effects | Immunity, Innate - drug effects | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Cells, Cultured | Solubility | Saponins - analysis | Macrophages - cytology | Th2 Cells - metabolism | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | Lipid A - pharmacology | Macrophages - drug effects | Dendritic Cells - cytology | GTP-Binding Proteins - metabolism | Saponins - pharmacology | vaccine | Immunology | human immunodeficiency virus (HIV) | caspase 1 (CASP1) | inflammasome | saponin | NLRP3 | Toll-like receptor 4 (TLR4) | monophosphoryl lipid A | adjuvants
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 03/2019, Volume 16, Issue 1, pp. 52 - 17
...), we studied the effect of ALX on the maturation of dendritic cells (DCs) and the responses of effector and regulatory T cells (Tregs... 
Experimental autoimmune encephalomyelitis | AKT | Amlexanox | TBK1 | Dendritic cells | IRF3 | TARGET | ACTIVATION | IKK-EPSILON | SUBSETS | MODEL | IMMUNOLOGY | NEUROSCIENCES | THERAPY | MULTIPLE-SCLEROSIS | DIFFERENTIATION | Interferon Regulatory Factor-3 - drug effects | Encephalomyelitis, Autoimmune, Experimental - immunology | Th1 Cells - immunology | T-Lymphocytes, Regulatory - immunology | Th17 Cells - drug effects | T-Lymphocytes - drug effects | Dendritic Cells - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Th1 Cells - drug effects | Mice, Inbred C57BL | Cell Differentiation - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Aminopyridines - pharmacology | Protein-Serine-Threonine Kinases - drug effects | Interferon Regulatory Factor-3 - metabolism | Th17 Cells - immunology | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Proto-Oncogene Proteins c-akt - drug effects | Immune response | Encephalomyelitis | Anti-inflammatory drugs | Patient outcomes | Development and progression | Observations | Autoimmune diseases | Drug therapy | Cell proliferation | Cell culture | Multiple sclerosis | Phosphorylation | Oligodendrocyte-myelin glycoprotein | CD86 antigen | Helper cells | Homeostasis | Effector cells | Nervous system | AKT protein | Interleukin 23 | Lymphocytes T | Kinases | Cell activation | Demyelination | Lymphocytes | Rodents | Interleukin 1 | Bone marrow | Spleen | Antigens | Cytokines | Immunoregulation | Interleukin 12 | Data processing | Cardiomyocytes | CD80 antigen | Inflammation | Anti-inflammatory agents | Experimental allergic encephalomyelitis | Interferon regulatory factor 3
Journal Article