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The Journal of infectious diseases, ISSN 1537-6613, 01/2015, Volume 211, Issue 1, pp. 156 - 165
Background. A predominantly T-helper type 2 (Th2) immune response is critical in the prognosis of pulmonary Pseudomonas aeruginosa infection. But the mucosal... 
human-milk | cytokine production | butyrate | in-vitro | chain fatty-acids | galacto-oligosaccharides | t-cells | lactobacillus | virus-infection | cystic-fibrosis patients | intestinal microbiota | prebiotics | Th1 and M1 polarization | P. aeruginosa lung infection | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Intestines - drug effects | Lung Diseases - microbiology | GATA3 Transcription Factor - immunology | Pseudomonas aeruginosa - growth & development | Microbiota - drug effects | Male | T-Box Domain Proteins - immunology | Lung Diseases - drug therapy | Th1 Cells - immunology | Intestines - immunology | Leukocytes - immunology | Oligosaccharides - pharmacology | Leukocytes - microbiology | Tumor Necrosis Factor-alpha - immunology | Keratinocytes - microbiology | Macrophages - immunology | Macrophages - microbiology | Chemotactic Factors - immunology | Microbiota - immunology | Pseudomonas Infections - drug therapy | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | Keratinocytes - immunology | Pectins - chemistry | Pseudomonas Infections - immunology | Lung Diseases - immunology | Interleukin-4 - immunology | Th1 Cells - microbiology | Animals | Intestines - microbiology | Interferon-gamma - immunology | Mice | Mice, Inbred BALB C | Interleukin-10 - immunology | Index Medicus | Abridged Index Medicus | Pseudomonas Infections/microbiology | Macrophages/microbiology | Oligosaccharides/pharmacology | Macrophages/immunology | Lung Diseases/immunology | Lung Diseases/microbiology | Interferon-gamma/immunology | Keratinocytes/microbiology | Microbiota/drug effects | Life Sciences | Leukocytes/microbiology | Pseudomonas Infections/immunology | Interleukin-10/immunology | Lung Diseases/drug therapy | T-Box Domain Proteins/immunology | Leukocytes/immunology | Pseudomonas aeruginosa/drug effects | Th1 Cells/microbiology | GATA3 Transcription Factor/immunology | Interleukin-4/immunology | Intestines/drug effects | Intestines/microbiology | Keratinocytes/immunology | Chemotactic Factors/immunology | Tumor Necrosis Factor-alpha/immunology | Microbiota/immunology | Pseudomonas aeruginosa/growth & development | Pectins/chemistry | Pseudomonas Infections/drug therapy | Th1 Cells/immunology | Intestines/immunology
Journal Article
Infection and immunity, ISSN 1098-5522, 03/2014, Volume 82, Issue 3, pp. 937 - 948
Journal Article
PloS one, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, pp. e24776 - e24776
.... First, we determined the cytokine pattern induced by 21 Bifidobacterium strains in peripheral blood mononuclear cells (PBMCs... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Bifidobacterium - immunology | Tumor Necrosis Factor-alpha - metabolism | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Species Specificity | Dendritic Cells - immunology | Humans | Interleukin-17 - immunology | Monocytes - metabolism | Monocytes - immunology | Th2 Cells - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | Host-Pathogen Interactions - immunology | T-Lymphocytes, Regulatory - immunology | Th2 Cells - microbiology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Flow Cytometry | Th17 Cells - metabolism | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Bifidobacterium - physiology | Dendritic Cells - metabolism | Leukocytes, Mononuclear - microbiology | Cytokines - immunology | Monocytes - microbiology | T-Lymphocytes, Regulatory - microbiology | CD4-Positive T-Lymphocytes - microbiology | Cytokines - metabolism | Bifidobacterium - classification | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Th2 Cells - metabolism | Interleukin-17 - metabolism | Th1 Cells - microbiology | Interferon-gamma - immunology | Dendritic Cells - microbiology | Th17 Cells - immunology | Interleukin-10 - immunology | Th17 Cells - microbiology | Bacteria | Dendritic cells | T cells | Tumor necrosis factor | Analysis | Dairy products | Genomics | Mucosa | Helper cells | Leukocytes (mononuclear) | Biochemistry | Lymphocytes T | Inductors | Cell activation | Microorganisms | Immunology | Lymphocytes | Plasticity | Peripheral blood mononuclear cells | Strains (organisms) | Immune system | Antigens | Automation | Immune response | Cytokines | Interleukin 12 | T cell receptors | Tumor necrosis factor-α | Metabolism | Immunological tolerance | Interleukin 17 | CD4 antigen | Inflammatory bowel disease | Probiotics | γ-Interferon | Interleukin 10 | Proteomics | Plastic properties | Differentiation | Index Medicus
Journal Article
PLoS pathogens, ISSN 1553-7374, 01/2018, Volume 14, Issue 1, pp. e1006726 - e1006726
.... To focus on the pathogen species, we compared in the same individual the human adaptive T and B cell immune response to multiple strains of two major human pathogens, Staphylococcus aureus and Streptococcus pyogenes... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Leukocytes, Mononuclear - metabolism | Cell Proliferation | Species Specificity | Humans | Th1 Cells - immunology | Streptococcus pyogenes - genetics | Th1 Cells - metabolism | Methicillin-Resistant Staphylococcus aureus - pathogenicity | Streptococcus pyogenes - pathogenicity | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Leukocytes, Mononuclear - immunology | Adult | Th17 Cells - cytology | Methicillin Resistance | Methicillin-Resistant Staphylococcus aureus - genetics | B-Lymphocytes - metabolism | Leukocytes, Mononuclear - microbiology | Staphylococcus aureus - metabolism | Adaptive Immunity | Biomarkers - metabolism | Staphylococcus aureus - genetics | B-Lymphocytes - cytology | B-Lymphocytes - microbiology | Genome, Bacterial | Reproducibility of Results | T-Lymphocytes - microbiology | Streptococcus pyogenes - immunology | Cells, Cultured | Vancomycin Resistance | Methicillin-Resistant Staphylococcus aureus - immunology | Streptococcus pyogenes - metabolism | Gene Knockout Techniques | Staphylococcus aureus - pathogenicity | Methicillin-Resistant Staphylococcus aureus - metabolism | Th1 Cells - microbiology | B-Lymphocytes - immunology | T-Lymphocytes - cytology | Th17 Cells - immunology | Leukocytes, Mononuclear - cytology | Staphylococcus aureus - immunology | T-Lymphocytes - immunology | Th1 Cells - cytology | Th17 Cells - microbiology | Genetic aspects | Immune response | Research | Staphylococcus | Pathogens | Bacterial infections | Cytokines | Laboratories | Pathogenesis | Variability | Phages | Helper cells | Staphylococcus infections | Genomes | Lymphocytes T | T cell receptors | Heterogeneity | Signal transduction | Immunology | Lymphocytes B | Lymphocytes | Bacteria | Prophages | Species | Strains (organisms) | Immune system | Index Medicus
Journal Article
PLoS pathogens, ISSN 1553-7366, 05/2017, Volume 13, Issue 5, pp. e1006357 - e1006357
.... Although it is known that MyD88-deficient mice are highly susceptible to a wide range of bacterial infections, the cell type-specific contribution of MyD88 in protecting the host against intestinal... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Dendritic Cells - immunology | Colon - immunology | Th1 Cells - immunology | Enterobacteriaceae Infections - immunology | Intestinal Mucosa - immunology | Toll-Like Receptors - metabolism | Macrophages - immunology | Macrophages - microbiology | Citrobacter rodentium - immunology | Signal Transduction | Enterobacteriaceae Infections - microbiology | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | Enterobacteriaceae Infections - pathology | Intestinal Mucosa - microbiology | Gene Knock-In Techniques | Receptors, Interleukin-1 - metabolism | Th1 Cells - microbiology | Animals | Epithelial Cells - immunology | Epithelial Cells - microbiology | Toll-Like Receptors - genetics | Dendritic Cells - microbiology | Th17 Cells - immunology | Colon - microbiology | Mice | Myeloid Differentiation Factor 88 - metabolism | Th17 Cells - microbiology | Bacterial infections | Dendritic cells | Gastrointestinal diseases | Analysis | Genetic aspects | Research | T cells | Health aspects | Risk factors | Infection control | Epithelial cells | Helper cells | Infections | Activation | Lymphocytes T | Interleukin 1 receptors | Macrophages | Immunity | Medical schools | Proteins | Receptors | Immunology | Lymphocytes | Intestine | Interleukin 1 | Toll-like receptors | Bacteria | Immune system | CD11c antigen | Pathogens | Immune response | Joint ventures | Epithelium | MyD88 protein | Index Medicus
Journal Article
PLoS pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 6, pp. e1004176 - e1004176
We previously reported interferon gamma secretion by human CD4(+) and CD8(+) T cells in response to recombinant E... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Recombinant Proteins - therapeutic use | Bacterial Proteins - adverse effects | Mycobacterium bovis - immunology | Spleen - immunology | Dendritic Cells - immunology | Mycobacterium tuberculosis - immunology | Th17 Cells - secretion | BCG Vaccine - antagonists & inhibitors | Spleen - microbiology | Th1 Cells - metabolism | Th17 Cells - metabolism | Glycoproteins - genetics | Glycoproteins - therapeutic use | Macrophages, Peritoneal - immunology | Glycoproteins - adverse effects | Glycosylation | Macrophages, Peritoneal - secretion | Dendritic Cells - secretion | Tuberculosis - prevention & control | Dendritic Cells - microbiology | Th17 Cells - immunology | Mice, Inbred BALB C | Protein Processing, Post-Translational | Th1 Cells - secretion | Macrophages, Peritoneal - metabolism | Cell Polarity | Glycoproteins - metabolism | Tuberculosis - microbiology | Recombinant Proteins - adverse effects | Th1 Cells - immunology | Bacterial Proteins - therapeutic use | Inflammation Mediators - metabolism | Female | Mycobacterium tuberculosis - metabolism | Tuberculosis - metabolism | Dendritic Cells - metabolism | Adaptive Immunity | Recombinant Proteins - metabolism | Bacterial Proteins - genetics | Cells, Cultured | Recombinant Proteins - genetics | Tuberculosis - immunology | Th1 Cells - microbiology | Animals | Macrophages, Peritoneal - microbiology | Mycobacterium bovis - metabolism | Spleen - metabolism | BCG Vaccine - adverse effects | Bacterial Proteins - metabolism | Immunologic Memory | BCG Vaccine - therapeutic use | Th17 Cells - microbiology | Tuberculosis | Dendritic cells | Distribution | Physiological aspects | Development and progression | Interferon | B cells | Biological response modifiers | T cells | Health aspects | Index Medicus | Proteins | Studies | Cytokines | E coli | Lymphocytes | Vaccines | Immune system | Cell adhesion & migration
Journal Article
PLoS pathogens, ISSN 1553-7374, 07/2013, Volume 9, Issue 7, pp. e1003472 - e1003472
We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Th1 Cells - pathology | Lung - microbiology | Tuberculosis, Pulmonary - microbiology | Up-Regulation | Skin - microbiology | Skin - metabolism | Dendritic Cells - immunology | Mycobacterium tuberculosis - immunology | Neutrophil Infiltration | Th1 Cells - metabolism | Immunity, Humoral | B-Lymphocytes - pathology | Neutrophils - metabolism | B-Lymphocytes - metabolism | Specific Pathogen-Free Organisms | Lymph Nodes - metabolism | Lymph Nodes - immunology | Tuberculosis, Pulmonary - pathology | Tuberculosis, Pulmonary - prevention & control | B-Lymphocytes - immunology | BCG Vaccine - immunology | Ear | Dendritic Cells - microbiology | Immunization, Passive | Mice | Lymph Nodes - pathology | Dendritic Cells - pathology | Th1 Cells - immunology | Female | Lung - metabolism | Neutrophils - microbiology | Dendritic Cells - metabolism | Skin - pathology | Injections, Intradermal | Neutrophils - pathology | Skin - immunology | B-Lymphocytes - microbiology | Lung - pathology | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-17 - biosynthesis | Th1 Cells - microbiology | Tuberculosis, Pulmonary - immunology | Animals | Interleukin-17 - antagonists & inhibitors | BCG Vaccine - therapeutic use | BCG Vaccine - administration & dosage | Lung - immunology | Lymph Nodes - microbiology | Prevention | Mycobacterium tuberculosis | Interleukins | Neutrophilia | Physiological aspects | B cells | Health aspects | Index Medicus | Infections | Tuberculosis | Rodents | Immune system
Journal Article