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by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Index Medicus | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0175904 - e0175904
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e82291 - e82291
Background: Recent studies suggest that acute sleep deprivation disrupts cellular immune responses by shifting T helper (Th) cell activity towards a Th2... 
CELLS | GROWTH-HORMONE | DEPRIVATION | IMMUNE-RESPONSES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | ASTHMA | PROLACTIN | DURATION | CORTISOL | Th1 Cells - drug effects | Chemokines - biosynthesis | Sleep Deprivation - immunology | Humans | Th1-Th2 Balance | Hydrocortisone - metabolism | Male | Phytohemagglutinins - immunology | Th2 Cells - immunology | Mitogens - immunology | Th1 Cells - immunology | Th2 Cells - drug effects | Young Adult | Adult | Leukocyte Count | Chemokines - immunology | Corticosteroids | Interleukins | Analysis | Research | Stress (Psychology) | Mitogens | Sleep deprivation | Neurosciences | Disease | Laboratories | Interleukin | Alcohol | Leukocytes (mononuclear) | Lymphocytes T | Hydrocortisone | Males | Interleukin 4 | Interleukin 2 | Physiology | Chronic obstructive pulmonary disease | Sleep and wakefulness | Psychological stress | Deprivation | Immune response | Cytokines | Secretion | Inflammation | Tumor necrosis factor-α | Asthma | White blood cells | Medicine | Studies | Sleep | Monocyte chemoattractant protein | Growth hormones | Chemokines | Monocyte chemoattractant protein 1 | Integrative medicine | Long-term effects | Index Medicus | Samhällsvetenskap | Social Sciences | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Psychology | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Psykologi | Health Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e45224 - e45224
Previously we have screened out Insulin-like Growth Factor Binding Protein 7 (IGFBP7) as a differentially expressed gene in post-implantation uterus versus... 
CYTOKINES | EARLY-PREGNANCY | DNA METHYLATION | ANGIOGENESIS | GROWTH-FACTOR VEGF | IMPLANTATION | MULTIDISCIPLINARY SCIENCES | FETAL | EXPRESSION | PROTEIN-RELATED PROTEIN-1 | T-CELLS | GATA3 Transcription Factor - genetics | Pregnancy, Animal | Proto-Oncogene Proteins c-bcl-2 - immunology | GATA3 Transcription Factor - immunology | Th1-Th2 Balance | Vaccines, DNA - immunology | Caspase 3 - immunology | Vascular Endothelial Growth Factor A - genetics | Vaccines, DNA - administration & dosage | Gene Expression Regulation, Developmental | Caspase 3 - genetics | Female | Interferon-gamma - genetics | Interleukin-4 - genetics | Insulin-Like Growth Factor Binding Proteins - genetics | Immunization | Epithelium - metabolism | Decidua - embryology | Insulin-Like Growth Factor Binding Protein 1 - immunology | Vascular Endothelial Growth Factor A - immunology | Embryo Implantation | Decidua - metabolism | Insulin-Like Growth Factor Binding Proteins - metabolism | Pregnancy | Interleukin-4 - immunology | Animals | Interferon-gamma - immunology | Interleukin-10 - genetics | Decidua - growth & development | Mice | Genetic Vectors | Insulin-Like Growth Factor Binding Proteins - antagonists & inhibitors | Interleukin-10 - immunology | Proto-Oncogene Proteins c-bcl-2 - genetics | Insulin-Like Growth Factor Binding Protein 1 - genetics | Embryonic development | Lymphocytes | Physiological aspects | Genetic aspects | Research | Binding proteins | Protein binding | Flow cytometry | Bcl-2 protein | Laboratories | Zoology | Insulin-like growth factor-binding protein 1 | Lymphocytes T | Biology | Kinases | Proteins | Angiogenesis | Interleukin 4 | Immunology | Uterus | Rodents | Cell cycle | Inhibition | Vascular endothelial growth factor | Deoxyribonucleic acid--DNA | Hypertension | Repressing | Cytokines | Stroma | Implantation | Epithelium | Insulin | Embryos | Cytometry | Preeclampsia | γ-Interferon | Infertility | Interleukin 10 | GATA-3 protein | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
STEM CELLS, ISSN 1066-5099, 08/2012, Volume 30, Issue 8, pp. 1664 - 1674
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease that results from cell‐mediated autoimmune destruction of insulin‐producing cells. In T1DM... 
Multipotent mesenchymal stromal cells | Pathophysiological markers | Regenerative medicine | Type 1 diabetes mellitus | Mesenchymal stem cells | DEPENDENT DIABETES-MELLITUS | IMMUNE-RESPONSE | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | BONE-MARROW | BETA-CELLS | LYMPH-NODES | MULTIPOTENT STROMAL CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EPIDERMAL-GROWTH-FACTOR | REGULATORY T-CELLS | INSULIN-PRODUCING CELLS | HEMATOLOGY | T-Lymphocytes, Regulatory - metabolism | Diabetes Mellitus, Experimental - surgery | Diabetes Mellitus, Type 1 - surgery | Humans | Pancreas - cytology | Th1-Th2 Balance | Diabetes Mellitus, Type 1 - metabolism | Male | Th2 Cells - immunology | Th1 Cells - immunology | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Insulin-Secreting Cells - metabolism | Cell Transdifferentiation - physiology | T-Lymphocytes, Regulatory - cytology | Insulin-Secreting Cells - cytology | Diabetes Mellitus, Type 1 - immunology | Diabetes Mellitus, Experimental - metabolism | Disease Models, Animal | Gene Expression | Mice, Inbred C57BL | Th2 Cells - cytology | Pancreas - metabolism | Pancreas - immunology | Th2 Cells - metabolism | Insulin-Secreting Cells - immunology | Diabetes Mellitus, Experimental - immunology | Animals | Mice | Th1 Cells - cytology | Mesenchymal Stem Cell Transplantation | Hyperglycemia | Epidermal growth factor | Type 1 diabetes | Analysis | Stem cells | Information management | T cells | Financial disclosure | Index Medicus
Journal Article