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PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24776
.... First, we determined the cytokine pattern induced by 21 Bifidobacterium strains in peripheral blood mononuclear cells (PBMCs... 
CYTOKINES | HUMAN DENDRITIC CELLS | T(H)17 CELLS | MULTIDISCIPLINARY SCIENCES | LACTIC-ACID BACTERIA | IN-VIVO | REGULATORY T-CELLS | PROINFLAMMATORY IL-17(+) | INDUCTION | SURFACE-MARKERS | INTESTINAL BACTERIA | Bifidobacterium - immunology | Tumor Necrosis Factor-alpha - metabolism | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Species Specificity | Dendritic Cells - immunology | Humans | Interleukin-17 - immunology | Monocytes - metabolism | Monocytes - immunology | Th2 Cells - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | Host-Pathogen Interactions - immunology | T-Lymphocytes, Regulatory - immunology | Th2 Cells - microbiology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Flow Cytometry | Th17 Cells - metabolism | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Bifidobacterium - physiology | Dendritic Cells - metabolism | Leukocytes, Mononuclear - microbiology | Cytokines - immunology | Monocytes - microbiology | T-Lymphocytes, Regulatory - microbiology | CD4-Positive T-Lymphocytes - microbiology | Cytokines - metabolism | Bifidobacterium - classification | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Th2 Cells - metabolism | Interleukin-17 - metabolism | Th1 Cells - microbiology | Interferon-gamma - immunology | Dendritic Cells - microbiology | Th17 Cells - immunology | Interleukin-10 - immunology | Th17 Cells - microbiology | Bacteria | Dendritic cells | T cells | Tumor necrosis factor | Analysis | Dairy products | Genomics | Mucosa | Helper cells | Leukocytes (mononuclear) | Biochemistry | Lymphocytes T | Inductors | Cell activation | Microorganisms | Immunology | Lymphocytes | Plasticity | Peripheral blood mononuclear cells | Strains (organisms) | Immune system | Antigens | Automation | Immune response | Cytokines | Interleukin 12 | T cell receptors | Tumor necrosis factor-α | Metabolism | Immunological tolerance | Interleukin 17 | CD4 antigen | Inflammatory bowel disease | Probiotics | γ-Interferon | Interleukin 10 | Proteomics | Plastic properties | Differentiation
Journal Article
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2014, Volume 4, Issue 1, p. 5865
In a murine model of allergic asthma, we found that Tyk-2((-/-)) asthmatic mice have induced peribronchial collagen deposition, mucosal type mast cells in the lung, IRF4 and hyperproliferative lung Th2 CD4... 
INFLAMMATION IN-VIVO | TGF-BETA | INTERLEUKIN-17 | TYK2-DEFICIENT MICE | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | AIRWAY INFLAMMATION | PHENOTYPE | EXPRESSION | HYPERRESPONSIVENESS | IL-21 | Asthma - metabolism | Cell Proliferation | Ovalbumin - immunology | TYK2 Kinase - metabolism | Th2 Cells - immunology | Interleukin-17 - pharmacology | Recombinant Proteins - biosynthesis | CD4-Positive T-Lymphocytes - immunology | T-Lymphocytes, Helper-Inducer - drug effects | Th17 Cells - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Asthma - immunology | Th17 Cells - cytology | Cell Differentiation | Lung - metabolism | Disease Models, Animal | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | CD4-Positive T-Lymphocytes - cytology | Interleukin-17 - genetics | Th2 Cells - cytology | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Th2 Cells - metabolism | Mice, Knockout | Interleukin-17 - metabolism | Suppressor of Cytokine Signaling 3 Protein | Phenotype | Animals | Th17 Cells - immunology | Mice | Mice, Inbred BALB C | Suppressor of Cytokine Signaling Proteins - metabolism | TYK2 Kinase - genetics | Asthma - pathology | Animal models | Mucosa | Helper cells | Effector cells | Lymphocytes T | Interleukin 6 | Interleukin 4 | Interleukin 5 | Interleukin 3 | Rodents | Interleukin 21 | CD25 antigen | Foxp3 protein | Interleukin 9 | Immunoregulation | Interleukin 13 | Asthma | CD4 antigen | Lungs | Interferon regulatory factor 4 | Collagen | Interleukin 10 | Mast cells | Autoimmune diseases | Cancer
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2013, Volume 38, Issue 5, pp. 970 - 983
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2015, Volume 163, Issue 6, pp. 1400 - 1412
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2017, Volume 46, Issue 4, pp. 660 - 674
Regulatory T cells (Treg cells) perform suppressive functions in disparate tissue environments and against many inflammatory insults, yet the tissue-enriched factor... 
HOMEOSTASIS | TGF-BETA | AUTOIMMUNITY | INFLAMMATION | IN-VIVO | REG-CELLS | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | CD103 EXPRESSION | MEDIATED REGULATION | TH17 CELLS | Forkhead Transcription Factors - immunology | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Receptors, Transforming Growth Factor beta - genetics | Cell Proliferation | Receptors, Transforming Growth Factor beta - immunology | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, G-Protein-Coupled - metabolism | Encephalomyelitis, Autoimmune, Experimental - immunology | Gastrointestinal Tract - pathology | Antigens, CD - metabolism | Organ Specificity - immunology | Receptors, G-Protein-Coupled - immunology | T-Lymphocytes, Regulatory - immunology | Gastrointestinal Tract - immunology | Signal Transduction - immunology | Flow Cytometry | Th17 Cells - metabolism | Forkhead Transcription Factors - metabolism | Integrin alpha Chains - immunology | Encephalomyelitis, Autoimmune, Experimental - genetics | Protein-Serine-Threonine Kinases - metabolism | Transforming Growth Factor beta - immunology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Homeostasis - immunology | Mice, Transgenic | Integrin alpha Chains - metabolism | Forkhead Transcription Factors - genetics | Gastrointestinal Tract - metabolism | Mice, Knockout | Animals | Receptors, Transforming Growth Factor beta - metabolism | Th17 Cells - immunology | Protein-Serine-Threonine Kinases - immunology | Transforming Growth Factor beta - metabolism | Transcription factors | Immune response | Differentiation (biology) | Homeostasis | Nervous system | Inflammation | Lymphocytes T | Gastrointestinal tract | Cell differentiation | Lymphocytes | Rodents | Regulation | Colon | Immune system
Journal Article
Cancer Research, ISSN 0008-5472, 02/2011, Volume 71, Issue 4, pp. 1263 - 1271
The tumor microenvironment includes a complex network of immune T-cell subpopulations... 
BREAST-CANCER | SURVIVAL | LUNG-CANCER | FOXP3 EXPRESSION | RECRUITMENT | ONCOLOGY | GASTRIC-CANCER | EOSINOPHILS | MACROPHAGES | CARCINOMA | LYMPHOCYTES | Th1 Cells - pathology | Th1 Cells - physiology | Prognosis | Th2 Cells - physiology | Tissue Array Analysis | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma - mortality | Gene Expression Profiling | Th2 Cells - immunology | Th1 Cells - immunology | Colorectal Neoplasms - diagnosis | Lymphocytes, Tumor-Infiltrating - physiology | T-Lymphocytes, Cytotoxic - pathology | Th1 Cells - metabolism | Th17 Cells - metabolism | Forkhead Transcription Factors - metabolism | Microarray Analysis | T-Lymphocytes, Helper-Inducer - immunology | Lymphocytes, Tumor-Infiltrating - metabolism | T-Lymphocytes, Helper-Inducer - pathology | Interleukin-4 - genetics | Th2 Cells - pathology | Th17 Cells - pathology | Colorectal Neoplasms - mortality | T-Lymphocytes, Cytotoxic - immunology | Th17 Cells - physiology | T-Lymphocytes, Helper-Inducer - metabolism | Carcinoma - immunology | Interleukin-4 - metabolism | Carcinoma - diagnosis | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | T-Lymphocytes, Cytotoxic - physiology | T-Lymphocytes, Helper-Inducer - physiology | Colorectal Neoplasms - immunology | Lymphocytes, Tumor-Infiltrating - pathology | T-Lymphocytes, Cytotoxic - metabolism | Survival Analysis | Th17 Cells - immunology | Carcinoma - genetics | Cohort Studies | Lymphocytes, Tumor-Infiltrating - immunology
Journal Article
PLoS pathogens, ISSN 1553-7374, 2018, Volume 14, Issue 1, p. e1006726
.... To focus on the pathogen species, we compared in the same individual the human adaptive T and B cell immune response to multiple strains of two major human pathogens, Staphylococcus aureus and Streptococcus pyogenes... 
HYPER-IGE SYNDROME | STREPTOCOCCUS-PYOGENES | CELLS | VIROLOGY | NEWMAN | IFN-GAMMA | MICROBIOLOGY | VIRULENCE | PARASITOLOGY | Leukocytes, Mononuclear - metabolism | Cell Proliferation | Species Specificity | Humans | Th1 Cells - immunology | Streptococcus pyogenes - genetics | Th1 Cells - metabolism | Methicillin-Resistant Staphylococcus aureus - pathogenicity | Streptococcus pyogenes - pathogenicity | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Leukocytes, Mononuclear - immunology | Adult | Th17 Cells - cytology | Methicillin Resistance | Methicillin-Resistant Staphylococcus aureus - genetics | B-Lymphocytes - metabolism | Leukocytes, Mononuclear - microbiology | Staphylococcus aureus - metabolism | Adaptive Immunity | Biomarkers - metabolism | Staphylococcus aureus - genetics | B-Lymphocytes - cytology | B-Lymphocytes - microbiology | Genome, Bacterial | Reproducibility of Results | T-Lymphocytes - microbiology | Streptococcus pyogenes - immunology | Cells, Cultured | Vancomycin Resistance | Methicillin-Resistant Staphylococcus aureus - immunology | Streptococcus pyogenes - metabolism | Gene Knockout Techniques | Staphylococcus aureus - pathogenicity | Methicillin-Resistant Staphylococcus aureus - metabolism | Th1 Cells - microbiology | B-Lymphocytes - immunology | T-Lymphocytes - cytology | Th17 Cells - immunology | Leukocytes, Mononuclear - cytology | Staphylococcus aureus - immunology | T-Lymphocytes - immunology | Th1 Cells - cytology | Th17 Cells - microbiology | Genetic aspects | Immune response | Research | Staphylococcus | Pathogens | Bacterial infections | Cytokines | Laboratories | Pathogenesis | Variability | Phages | Helper cells | Staphylococcus infections | Genomes | Lymphocytes T | T cell receptors | Heterogeneity | Signal transduction | Immunology | Lymphocytes B | Lymphocytes | Bacteria | Prophages | Species | Strains (organisms) | Immune system
Journal Article
Stem cell research & therapy, ISSN 1757-6512, 2013, Volume 4, Issue 3, pp. 65 - 65
Journal Article