FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 07/2019, Volume 10, p. 1619
Systemic lupus erythematosus (SLE) is an autoimmune disease that involves multiple immune cell subsets. We analyzed immune cell subsets in human peripheral...
FOXP3 EXPRESSION | LAGS | systematic lupus erythematosus | TREG | PHENOTYPE | IMMUNOLOGY | IDENTIFICATION | DIFFERENTIATE | SUBSET | regulatory T cells | SLEDAI | GROWTH-FACTOR-BETA | LAG-3 | Th17 | BLOOD | Rheumatoid factor | Lymphocytes | Systemic lupus erythematosus | Killer cells | Diagnosis | Research | T cells | LAG3
FOXP3 EXPRESSION | LAGS | systematic lupus erythematosus | TREG | PHENOTYPE | IMMUNOLOGY | IDENTIFICATION | DIFFERENTIATE | SUBSET | regulatory T cells | SLEDAI | GROWTH-FACTOR-BETA | LAG-3 | Th17 | BLOOD | Rheumatoid factor | Lymphocytes | Systemic lupus erythematosus | Killer cells | Diagnosis | Research | T cells | LAG3
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Full Text
Psoriasis or atopic eczema: skin-infiltrating effector memory T cells make the difference
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 01/2012, Volume 63, Issue 1, p. 52
Psoriasis - immunology | Psoriasis - drug therapy | Staphylococcus aureus - isolation & purification | Humans | Middle Aged | Male | Dermatitis, Atopic - microbiology | Th2 Cells - immunology | Th1 Cells - immunology | Dermatitis, Atopic - complications | Psoriasis - complications | Dermatitis, Atopic - drug therapy | T-Lymphocytes, Helper-Inducer - immunology | Adolescent | Dermatitis, Atopic - immunology | Th17 Cells - immunology | Adult | Female | Interleukin-4 - therapeutic use | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Revista Brasileira de Reumatologia, ISSN 0482-5004, 01/2016, Volume 56, Issue 1, pp. 28 - 36
Evidências recentes sugerem que anormalidades que envolvem os linfócitos Th17 estão associadas à fisiopatologia do lúpus eritematoso sistêmico (LES). Além...
T lymphocytes | Systemic lupus erythematosus | Lúpus eritematoso sistêmico | Th17 | Multifunctional T cells | Linfócitos T | Linfócitos T multifuncionais
T lymphocytes | Systemic lupus erythematosus | Lúpus eritematoso sistêmico | Th17 | Multifunctional T cells | Linfócitos T | Linfócitos T multifuncionais
Journal Article
ZEITSCHRIFT FUR RHEUMATOLOGIE, ISSN 0340-1855, 06/2013, Volume 72, Issue 5, pp. 457 - 457
GAMMA | TGF-BETA | PATHOGENIC T(H)17 CELLS | IL-17-PRODUCING T-CELLS | ANAKINRA | RHEUMATOLOGY | ARTHRITIS | IL-10 | Inflammation - pathology | Models, Immunological | Animals | Humans | Th17 Cells - immunology | Inflammation - immunology | Rheumatic Diseases - pathology | Cytokines - immunology | Immunomodulation - immunology | Rheumatic Diseases - immunology
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Zeitschrift fur Rheumatologie, ISSN 0340-1855, 07/2009, Volume 68, Issue 5, pp. 405 - 408
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Revista Cubana de Hematologia, Inmunologia y Hemoterapia, ISSN 0864-0289, 10/2012, Volume 28, Issue 4, pp. 357 - 373
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Revista Cubana de Hematología, Inmunología y Hemoterapia, ISSN 0864-0289, 12/2012, Volume 28, Issue 4, pp. 357 - 373
La psoriasis es una enfermedad inflamatoria crónica de la piel mediada por células T que afecta a individuos con predisposición genética y presenta varios...
inmunopatogenia | IFNa | plasmacytoid dendritic cells | células T | immunopathogenesis | células Th17 | psoriasis | IL-23/Th17 axis | T cells | células dendríticas plasmacitoides | eje IL-23/Th17 | Th17 cells
inmunopatogenia | IFNa | plasmacytoid dendritic cells | células T | immunopathogenesis | células Th17 | psoriasis | IL-23/Th17 axis | T cells | células dendríticas plasmacitoides | eje IL-23/Th17 | Th17 cells
Journal Article
Allergologie, ISSN 0344-5062, 05/2010, Volume 33, Issue 5, pp. 211 - 214
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Expanding immunotherapy: new T-helper-cell populations at the center of new therapeutic strategies
ALLERGOLOGIE, ISSN 0344-5062, 05/2010, Volume 33, Issue 5, pp. 211 - 214
GAMMA | IMMUNITY | T cell | KERATINOCYTES | Th22 | INTERLEUKIN-17 | ALLERGY | immunotherapy | IL-17 | DIFFERENTIATION | Th17 | EXPRESSION | TH17 CELLS | LYMPHOCYTES
Journal Article
Immunity, ISSN 1074-7613, 2011, Volume 34, Issue 4, pp. 554 - 565
T helper 17 (Th17) cells are important for host defense against extracellular microorganisms. However, they are also implicated in autoimmune and chronic...
INTESTINAL INFLAMMATION | CRUCIAL ROLE | RESPONSES | INFLAMMATORY-BOWEL-DISEASE | TGF-BETA | COLITIS | T(H)17 | MICE | DIFFERENTIATION | IMMUNOLOGY | IL-10 | Forkhead Transcription Factors - immunology | Cell Proliferation | Signal Transduction | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Colitis - pathology | Interleukin-10 Receptor alpha Subunit - immunology | Disease Progression | CD4-Positive T-Lymphocytes - immunology | Animals | Th17 Cells - metabolism | Interferon-gamma - immunology | Peptide Fragments - immunology | Interleukin-10 Receptor alpha Subunit - metabolism | Interleukin-10 - metabolism | Th17 Cells - immunology | Th17 Cells - cytology | Mice | Colitis - immunology | Interleukin-10 - immunology | Inflammatory bowel disease | Transcription factors | Small intestine | Rodents | Cloning
INTESTINAL INFLAMMATION | CRUCIAL ROLE | RESPONSES | INFLAMMATORY-BOWEL-DISEASE | TGF-BETA | COLITIS | T(H)17 | MICE | DIFFERENTIATION | IMMUNOLOGY | IL-10 | Forkhead Transcription Factors - immunology | Cell Proliferation | Signal Transduction | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Colitis - pathology | Interleukin-10 Receptor alpha Subunit - immunology | Disease Progression | CD4-Positive T-Lymphocytes - immunology | Animals | Th17 Cells - metabolism | Interferon-gamma - immunology | Peptide Fragments - immunology | Interleukin-10 Receptor alpha Subunit - metabolism | Interleukin-10 - metabolism | Th17 Cells - immunology | Th17 Cells - cytology | Mice | Colitis - immunology | Interleukin-10 - immunology | Inflammatory bowel disease | Transcription factors | Small intestine | Rodents | Cloning
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 07/2014, Volume 96, Issue 1, pp. 39 - 48
Review of the development and properties of a new identified T cell subset: IL‐17+Foxp3+ T cells. Foxp3+ Tregs have been known as a major regulator of immune...
immune system | tumor microenvironment | inflammation | RORγt | Inflammation | Tumor microenvironment | Immune system | TGF-BETA | ROR-GAMMA-T | ROR gamma t | PROINFLAMMATORY CYTOKINES | IMMUNOLOGY | CUTTING EDGE | CELL BIOLOGY | GROWTH-FACTOR-BETA | T(H)17 CELLS | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | SUPPRESSIVE FUNCTION | TOLL-LIKE RECEPTORS | HEMATOLOGY | Humans | Autoimmune Diseases - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Neoplasms - therapy | Animals | Neoplasms - immunology | Autoimmune Diseases - therapy | Th17 Cells - immunology | Mice | Interleukin-17 | Neoplasms - pathology | Autoimmune Diseases - pathology | Forkhead Transcription Factors | Cytokines - immunology | Th17 Cells - pathology
immune system | tumor microenvironment | inflammation | RORγt | Inflammation | Tumor microenvironment | Immune system | TGF-BETA | ROR-GAMMA-T | ROR gamma t | PROINFLAMMATORY CYTOKINES | IMMUNOLOGY | CUTTING EDGE | CELL BIOLOGY | GROWTH-FACTOR-BETA | T(H)17 CELLS | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | SUPPRESSIVE FUNCTION | TOLL-LIKE RECEPTORS | HEMATOLOGY | Humans | Autoimmune Diseases - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Neoplasms - therapy | Animals | Neoplasms - immunology | Autoimmune Diseases - therapy | Th17 Cells - immunology | Mice | Interleukin-17 | Neoplasms - pathology | Autoimmune Diseases - pathology | Forkhead Transcription Factors | Cytokines - immunology | Th17 Cells - pathology
Journal Article
Immunity, ISSN 1074-7613, 03/2011, Volume 34, Issue 3, pp. 422 - 434
Th17 cells and CD4 CD25 Foxp3 regulatory T (Treg) cells are thought to promote and suppress inflammatory responses, respectively. Here we explore why under...
ORAL CANDIDIASIS | INTERLEUKIN-2 | RESPONSES | DEFENSE | PROTECTIVE IMMUNITY | HELPER | AUTOIMMUNITY | IL-17 | GENERATION | IMMUNOLOGY | Forkhead Transcription Factors - immunology | CD4 Antigens - immunology | Mice, Inbred C57BL | Candida albicans - immunology | Immunity, Innate | T-Lymphocytes, Regulatory - immunology | Animals | Th17 Cells - immunology | Th17 Cells - cytology | Cell Differentiation | Mice | Mice, Inbred BALB C | Candidiasis - immunology | Disease Models, Animal | Interleukin-2 Receptor alpha Subunit - immunology
ORAL CANDIDIASIS | INTERLEUKIN-2 | RESPONSES | DEFENSE | PROTECTIVE IMMUNITY | HELPER | AUTOIMMUNITY | IL-17 | GENERATION | IMMUNOLOGY | Forkhead Transcription Factors - immunology | CD4 Antigens - immunology | Mice, Inbred C57BL | Candida albicans - immunology | Immunity, Innate | T-Lymphocytes, Regulatory - immunology | Animals | Th17 Cells - immunology | Th17 Cells - cytology | Cell Differentiation | Mice | Mice, Inbred BALB C | Candidiasis - immunology | Disease Models, Animal | Interleukin-2 Receptor alpha Subunit - immunology
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 08/2012, Volume 209, Issue 9, pp. 1595 - 1609
Although very high levels of interleukin (IL)-1 beta are present in the intestines of patients suffering from inflammatory bowel diseases (IBD), little is...
ENHANCED PRODUCTION | DEPENDENT COLITIS | MEDICINE, RESEARCH & EXPERIMENTAL | T(H)17 CELLS | CROHNS-DISEASE | INTERLEUKIN-1 RECEPTOR ANTAGONIST | ULCERATIVE-COLITIS | REGULATORY T-CELLS | IMMUNOLOGY | AUTOINFLAMMATORY DISEASE | CYTOKINE GM-CSF | BOWEL-DISEASE | Colon - immunology | Helicobacter Infections - pathology | Receptors, Interleukin-1 Type I - metabolism | Interleukin-23 - metabolism | Lymphocytes - immunology | Th17 Cells - metabolism | Interleukin-1beta - metabolism | Helicobacter hepaticus - pathogenicity | Helicobacter Infections - metabolism | Colitis - immunology | Cell Survival | Colon - pathology | Interleukin-17 - secretion | Mice, Inbred C57BL | Helicobacter Infections - immunology | CD5 Antigens - metabolism | Immunity, Innate | Receptors, Interleukin-1 - metabolism | Interleukin-17 - metabolism | Animals | Colitis - microbiology | Colitis - metabolism | Th17 Cells - immunology | Colon - microbiology | Mice | Granulocytes - immunology
ENHANCED PRODUCTION | DEPENDENT COLITIS | MEDICINE, RESEARCH & EXPERIMENTAL | T(H)17 CELLS | CROHNS-DISEASE | INTERLEUKIN-1 RECEPTOR ANTAGONIST | ULCERATIVE-COLITIS | REGULATORY T-CELLS | IMMUNOLOGY | AUTOINFLAMMATORY DISEASE | CYTOKINE GM-CSF | BOWEL-DISEASE | Colon - immunology | Helicobacter Infections - pathology | Receptors, Interleukin-1 Type I - metabolism | Interleukin-23 - metabolism | Lymphocytes - immunology | Th17 Cells - metabolism | Interleukin-1beta - metabolism | Helicobacter hepaticus - pathogenicity | Helicobacter Infections - metabolism | Colitis - immunology | Cell Survival | Colon - pathology | Interleukin-17 - secretion | Mice, Inbred C57BL | Helicobacter Infections - immunology | CD5 Antigens - metabolism | Immunity, Innate | Receptors, Interleukin-1 - metabolism | Interleukin-17 - metabolism | Animals | Colitis - microbiology | Colitis - metabolism | Th17 Cells - immunology | Colon - microbiology | Mice | Granulocytes - immunology
Journal Article
Immunity, ISSN 1074-7613, 01/2011, Volume 34, Issue 1, pp. 108 - 121
Although a fraction of human blood memory CD4 T cells expresses chemokine (C-X-C motif) receptor 5 (CXCR5), their relationship to T follicular helper (Tfh)...
CHEMOKINE RECEPTOR EXPRESSION | B-CELLS | RESPONSES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | DENDRITIC CELLS | HUMAN TH17 CELLS | GENE-EXPRESSION | HELPER MEMORY CELLS | IMMUNOLOGY | IL-21 | CUTTING EDGE | Th1 Cells - pathology | Humans | Th1-Th2 Balance | Child, Preschool | Male | Th2 Cells - immunology | Th1 Cells - immunology | Th1 Cells - metabolism | Dermatomyositis - immunology | Th17 Cells - metabolism | Adult | Female | B-Lymphocytes - pathology | Child | B-Lymphocytes - metabolism | Th2 Cells - pathology | Th17 Cells - pathology | Paracrine Communication | Th2 Cells - metabolism | Disease Progression | B-Lymphocytes - immunology | Adolescent | Antibody Formation | Th17 Cells - immunology | Immunologic Memory | Receptors, CXCR5 - biosynthesis | CD4 Antigens - biosynthesis | Interleukins - secretion | Studies | Ligands | Cytokines | Autoimmune diseases | Rodents | Immune system
CHEMOKINE RECEPTOR EXPRESSION | B-CELLS | RESPONSES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | DENDRITIC CELLS | HUMAN TH17 CELLS | GENE-EXPRESSION | HELPER MEMORY CELLS | IMMUNOLOGY | IL-21 | CUTTING EDGE | Th1 Cells - pathology | Humans | Th1-Th2 Balance | Child, Preschool | Male | Th2 Cells - immunology | Th1 Cells - immunology | Th1 Cells - metabolism | Dermatomyositis - immunology | Th17 Cells - metabolism | Adult | Female | B-Lymphocytes - pathology | Child | B-Lymphocytes - metabolism | Th2 Cells - pathology | Th17 Cells - pathology | Paracrine Communication | Th2 Cells - metabolism | Disease Progression | B-Lymphocytes - immunology | Adolescent | Antibody Formation | Th17 Cells - immunology | Immunologic Memory | Receptors, CXCR5 - biosynthesis | CD4 Antigens - biosynthesis | Interleukins - secretion | Studies | Ligands | Cytokines | Autoimmune diseases | Rodents | Immune system
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2015, Volume 45, Issue 6, pp. 1868 - 1879
Alloimmunization against red blood cells (RBCs) is the main immunological risk associated with transfusion in patients with sickle cell disease (SCD). However,...
Jkb | Sickle cell disease | Th17 | Alloimmunization | CD4+ T cells | Jk b | CD4 + T cells | Autoimmunity | T-Lymphocyte Subsets - immunology | T-Lymphocyte Subsets - cytology | Humans | Middle Aged | Male | Case-Control Studies | CD4-Positive T-Lymphocytes - immunology | Young Adult | Lymphocyte Activation - immunology | Adult | Female | Anemia, Sickle Cell - immunology | Toll-Like Receptors - metabolism | Erythrocytes - immunology | Immunization | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Immunophenotyping | Transfusion Reaction | Anemia, Sickle Cell - therapy | Cell Differentiation - immunology | Phenotype | T-Lymphocyte Subsets - metabolism | Anemia, Sickle Cell - metabolism | Adolescent | Immunologic Memory | Cytokines - biosynthesis | Sickle cell anemia | T cells | Analysis
Jkb | Sickle cell disease | Th17 | Alloimmunization | CD4+ T cells | Jk b | CD4 + T cells | Autoimmunity | T-Lymphocyte Subsets - immunology | T-Lymphocyte Subsets - cytology | Humans | Middle Aged | Male | Case-Control Studies | CD4-Positive T-Lymphocytes - immunology | Young Adult | Lymphocyte Activation - immunology | Adult | Female | Anemia, Sickle Cell - immunology | Toll-Like Receptors - metabolism | Erythrocytes - immunology | Immunization | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Immunophenotyping | Transfusion Reaction | Anemia, Sickle Cell - therapy | Cell Differentiation - immunology | Phenotype | T-Lymphocyte Subsets - metabolism | Anemia, Sickle Cell - metabolism | Adolescent | Immunologic Memory | Cytokines - biosynthesis | Sickle cell anemia | T cells | Analysis
Journal Article
Nature Medicine, ISSN 1078-8956, 2014, Volume 20, Issue 1, pp. 62 - 68
Autoimmune diseases often result from an imbalance between regulatory T (Treg) cells and interleukin-17 (IL-17)-producing T helper (TH17) cells; the origin of...
Forkhead Transcription Factors - immunology | Oligonucleotide Array Sequence Analysis | CD4-Positive T-Lymphocytes - cytology | Humans | Mice, Inbred C57BL | Autoimmune Diseases - immunology | CD4-Positive T-Lymphocytes - metabolism | Synovial Membrane - immunology | Adoptive Transfer | Gene Knock-In Techniques | Cell Differentiation - immunology | Animals | Flow Cytometry | Forkhead Transcription Factors - metabolism | Arthritis - immunology | Th17 Cells - immunology | Th17 Cells - cytology | Mice | Synovial Membrane - cytology | Arthritis | T cell receptors | Cytokines | Autoimmune diseases | Pathogenesis
Forkhead Transcription Factors - immunology | Oligonucleotide Array Sequence Analysis | CD4-Positive T-Lymphocytes - cytology | Humans | Mice, Inbred C57BL | Autoimmune Diseases - immunology | CD4-Positive T-Lymphocytes - metabolism | Synovial Membrane - immunology | Adoptive Transfer | Gene Knock-In Techniques | Cell Differentiation - immunology | Animals | Flow Cytometry | Forkhead Transcription Factors - metabolism | Arthritis - immunology | Th17 Cells - immunology | Th17 Cells - cytology | Mice | Synovial Membrane - cytology | Arthritis | T cell receptors | Cytokines | Autoimmune diseases | Pathogenesis
Journal Article