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Nature Medicine, ISSN 1078-8956, 09/2016, Volume 22, Issue 9, pp. 991 - 993
Journal Article
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 15, pp. 2539 - 2549
Journal Article
Human Reproduction, ISSN 0268-1161, 04/2016, Volume 31, Issue 4, pp. 700 - 711
Abstract STUDY QUESTION Are the immune regulatory molecules programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) involved in regulating... 
CD4+T | miscarriage | Th2 bias | pregnancy | trophoblast | PD-1 | Tim-3 | ALLOGRAFT-REJECTION | IMMUNITY | PROTECTION | THYMIC STROMAL LYMPHOPOIETIN | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | COSTIMULATORY PATHWAYS | CD4(+)T | DIFFERENTIATION | PDL1 | EXHAUSTION | FETOMATERNAL TOLERANCE | Abortion, Habitual - pathology | Fetal Resorption - prevention & control | Coculture Techniques | Humans | Hepatitis A Virus Cellular Receptor 2 - metabolism | Abortion, Habitual - immunology | Fetal Resorption - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Th2 Cells - immunology | CD4-Positive T-Lymphocytes - pathology | Abortion, Habitual - metabolism | Pregnancy Trimester, First | Programmed Cell Death 1 Receptor - blood | Th2 Cells - drug effects | Abortion, Induced | CD4-Positive T-Lymphocytes - immunology | Hepatitis A Virus Cellular Receptor 2 - antagonists & inhibitors | Abortion, Habitual - blood | Antibodies, Neutralizing - therapeutic use | Female | Fetal Resorption - pathology | Maternal-Fetal Exchange - drug effects | Th2 Cells - pathology | Immune Tolerance - drug effects | Decidua - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Hepatitis A Virus Cellular Receptor 2 - blood | Programmed Cell Death 1 Receptor - metabolism | Antibodies, Neutralizing - pharmacology | Decidua - pathology | Fetal Resorption - immunology | Th2 Cells - metabolism | Decidua - metabolism | Pregnancy | Tocolytic Agents - pharmacology | Tocolytic Agents - therapeutic use | Animals | Cell Proliferation - drug effects | Mice | Decidua - drug effects | CD4-Positive T-Lymphocytes - drug effects | Crosses, Genetic | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 733 - 743
Journal Article
Experimental Cell Research, ISSN 0014-4827, 2010, Volume 316, Issue 19, pp. 3109 - 3123
Mesenchymal stromal cells (MSCs) have important immunosuppressive properties, but the mechanisms and soluble factors involved in these effects remain unclear.... 
T lymphocytes | Mesenchymal stromal cells | Prostaglandin E2 | Immunosuppressive properties | Dendritic cells | VERSUS-HOST-DISEASE | LYMPHOCYTE-PROLIFERATION | TRANSPLANTATION | CELL BIOLOGY | THERAPY | ONCOLOGY | ADULT STEM-CELLS | ANTIGEN-PRESENTING CELLS | DIFFERENTIATION | T-CELLS | INHIBIT | Dinoprostone - secretion | Mitogens - pharmacology | Coculture Techniques | Dendritic Cells - immunology | Humans | Adipose Tissue - cytology | Th2 Cells - immunology | RNA, Messenger - metabolism | Th1 Cells - immunology | Th2 Cells - drug effects | Mesenchymal Stromal Cells - immunology | Mesenchymal Stromal Cells - cytology | Immune Tolerance - immunology | Phytohemagglutinins - pharmacology | Stromal Cells - drug effects | Dendritic Cells - drug effects | Cytokines - genetics | Immune Tolerance - drug effects | Mesenchymal Stromal Cells - drug effects | Th1 Cells - drug effects | Bone Marrow Cells - cytology | RNA, Messenger - genetics | Cytokines - secretion | Immunophenotyping | Stromal Cells - immunology | Th2 Cells - cytology | Indomethacin - pharmacology | Dinoprostone - metabolism | Gene Expression Regulation - drug effects | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Cell Proliferation - drug effects | Dendritic Cells - cytology | Th1 Cells - cytology | Stromal Cells - cytology | Indomethacin | T cells | Prostaglandins E | Analysis | Stem cells | Bone marrow | Cell culture | Immunology | Cellular biology | Cytokines | Index Medicus | DENDRITES | TRANSCRIPTION FACTORS | LYMPHOKINES | PROSTAGLANDINS | INFLAMMATION | BONE MARROW | CELL PROLIFERATION | SECRETION | 60 APPLIED LIFE SCIENCES | ADIPOSE TISSUE | LYMPHOCYTES
Journal Article
Immunity, ISSN 1074-7613, 03/2014, Volume 40, Issue 3, pp. 425 - 435
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2017, Volume 198, Issue 8, pp. 3069 - 3080
Dimethyl fumarate (DMF; trade name Tecfidera) is an oral formulation of the fumaric acid ester that is Food and Drug Administration approved for treatment of... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | OXIDATIVE STRESS | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | PLACEBO-CONTROLLED PHASE-3 | SUBSETS | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | BLOOD-BRAIN-BARRIER | ORAL BG-12 | ACID ESTERS | TH17 CELLS | T-Lymphocyte Subsets - immunology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Th2 Cells - immunology | Immunologic Memory - drug effects | Th1 Cells - immunology | Th2 Cells - drug effects | Lymphocyte Activation - immunology | Th17 Cells - drug effects | Flow Cytometry | T-Lymphocyte Subsets - drug effects | Adult | Female | Immunologic Memory - immunology | Cell Survival - drug effects | Th1 Cells - drug effects | Multiple Sclerosis, Relapsing-Remitting - immunology | Cross-Sectional Studies | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Immunophenotyping | Dimethyl Fumarate - therapeutic use | Lymphocyte Activation - drug effects | Th17 Cells - immunology | Cell Proliferation - drug effects | Longitudinal Studies | Dimethyl | CC chemokine receptors | Flow cytometry | Reactive oxygen species | Multiple sclerosis | CD8 antigen | Helper cells | Effector cells | Activation | Lymphocytes T | Leukoencephalopathy | Progressive multifocal leukoencephalopathy | Interleukin 4 | Cell activation | Lymphocytes | Longitudinal studies | Immunological memory | Memory cells | Cell survival | CCR7 protein | Inflammation | CXCR3 protein | FDA approval | Patients | Interleukin 17 | CCR6 protein | CD4 antigen | Cytometry | Side effects | Fumaric acid | Correlation analysis | γ-Interferon | Interferon | Apoptosis | Index Medicus | Abridged Index Medicus | RRMS | Effector memory T cells | T helper cells | Dimethyl Fumarate | PBMC
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2016, Volume 291, Issue 3, pp. 1123 - 1136
Many immunostimulants act as vaccine adjuvants via activation of the innate immune system, although in many cases it is unclear which specific molecules... 
ADAPTIVE IMMUNITY | MONOPHOSPHORYL-LIPID-A | HEALTHY ADULT VOLUNTEERS | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NLRP3 INFLAMMASOME | T-CELL | ISCOMATRIX ADJUVANT | PARTICULATE VACCINE ADJUVANTS | QUILLAJA-SAPONARIA MOLINA | NALP3 INFLAMMASOME | HIV Envelope Protein gp120 - agonists | Lipid A - agonists | Adjuvants, Immunologic - analysis | Adjuvants, Immunologic - pharmacology | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Lipid A - analogs & derivatives | AIDS Vaccines - immunology | AIDS Vaccines - agonists | Th2 Cells - immunology | Th1 Cells - immunology | GTP-Binding Proteins - genetics | Th2 Cells - drug effects | Saponins - chemistry | HIV Envelope Protein gp120 - immunology | Th1 Cells - metabolism | Immunoglobulin G - biosynthesis | Inflammasomes - drug effects | Adjuvants, Immunologic - chemistry | Bone Marrow Cells - immunology | Bone Marrow Cells - drug effects | Dendritic Cells - drug effects | Immunoglobulin G - analysis | Macrophages - immunology | Cell Survival - drug effects | Th1 Cells - drug effects | Immunity, Innate - drug effects | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Cells, Cultured | Solubility | Saponins - analysis | Macrophages - cytology | Th2 Cells - metabolism | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | Lipid A - pharmacology | Macrophages - drug effects | Dendritic Cells - cytology | GTP-Binding Proteins - metabolism | Saponins - pharmacology | Index Medicus | vaccine | Immunology | human immunodeficiency virus (HIV) | caspase 1 (CASP1) | inflammasome | saponin | NLRP3 | Toll-like receptor 4 (TLR4) | monophosphoryl lipid A | adjuvants
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2010, Volume 185, Issue 11, pp. 6636 - 6645
Ambient particulate matter, including diesel exhaust particles (DEP), promotes the development of allergic disorders. DEP increase oxidative stress and... 
AMBIENT PARTICULATE MATTER | TH2 RESPONSES | AIR-POLLUTION | CYTOKINE PRODUCTION | CD4 T-CELLS | IMMUNE-RESPONSES | IN-VIVO | GATA3 EXPRESSION | ANTIGEN-PRESENTING CELLS | MEDIATED ALLERGIC INFLAMMATION | IMMUNOLOGY | Particulate Matter - toxicity | Vehicle Emissions - toxicity | Respiratory Mucosa - drug effects | Coculture Techniques | Dendritic Cells - immunology | Humans | Intercellular Signaling Peptides and Proteins - biosynthesis | Th2 Cells - immunology | OX40 Ligand - biosynthesis | Bronchi - immunology | Reactive Oxygen Species - toxicity | Th2 Cells - drug effects | Cytokines - physiology | Bronchi - drug effects | Signal Transduction - immunology | Receptors, Notch - biosynthesis | Myeloid Cells - immunology | Serrate-Jagged Proteins | Respiratory Mucosa - immunology | Stromal Cells - drug effects | Dendritic Cells - drug effects | Myeloid Cells - drug effects | Cell Polarity - drug effects | Bronchi - cytology | Dendritic Cells - metabolism | Jagged-1 Protein | Cell Polarity - immunology | Calcium-Binding Proteins - biosynthesis | Respiratory Mucosa - cytology | Stromal Cells - metabolism | Cells, Cultured | Thymus Gland - cytology | Stromal Cells - immunology | Thymus Gland - drug effects | Th2 Cells - metabolism | Up-Regulation - drug effects | Membrane Proteins - biosynthesis | Signal Transduction - drug effects | Up-Regulation - immunology | Myeloid Cells - metabolism | Thymus Gland - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2008, Volume 14, Issue 20, pp. 6674 - 6682
Purpose: Immune dysfunction is well documented in renal cell carcinoma (RCC) patients and likely contributes to tumor evasion. This dysfunction includes a... 
Type-1/Type-2 responses | T-regulatory cells | FoxP3 | Immune dysfunction | HEPATOCELLULAR-CARCINOMA | INTERFERON-ALPHA | CANCER-PATIENTS | CYTOKINE PRODUCTION | DENDRITIC CELLS | TUMOR REJECTION | ONCOLOGY | IN-VIVO | PERIPHERAL-BLOOD | ANTITUMOR IMMUNITY | ENDOTHELIAL GROWTH-FACTOR | T-Lymphocytes, Regulatory - metabolism | Humans | Middle Aged | Kidney - immunology | Kidney Neoplasms - immunology | Male | Antineoplastic Agents - therapeutic use | Kidney Neoplasms - metabolism | Th2 Cells - immunology | Interferon-gamma - metabolism | Recombinant Proteins | Th1 Cells - immunology | Th2 Cells - drug effects | Carcinoma, Renal Cell - immunology | Case-Control Studies | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Kidney - metabolism | Female | Carcinoma, Renal Cell - drug therapy | Pyrroles - therapeutic use | Th1 Cells - drug effects | Kidney - drug effects | Interleukin-4 - metabolism | CD4-Positive T-Lymphocytes - metabolism | CD3 Complex - metabolism | Th2 Cells - metabolism | Carcinoma, Renal Cell - metabolism | Interleukin-4 - immunology | Immunosuppression | T-Lymphocytes, Regulatory - drug effects | Interferon-gamma - immunology | CD3 Complex - immunology | Indoles - therapeutic use | Kidney Neoplasms - drug therapy | CD4-Positive T-Lymphocytes - drug effects | Index Medicus
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 08/2013, Volume 210, Issue 9, pp. 1823 - 1837
Journal Article