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Nature Structural and Molecular Biology, ISSN 1545-9993, 08/2014, Volume 21, Issue 9, pp. 803 - 809
Journal Article
Science, ISSN 0036-8075, 11/2018, Volume 362, Issue 6414, pp. 558 - 558
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2016, Volume 72, Issue 40, pp. 6136 - 6141
Click analogues of thalidomide were prepared from 3-azidoglutarimide and a diverse array of arylacetylenes and -ethynyl/ -propargyl phthalimide derivatives.... 
Teratogenesis | Angiogenesis | TNF-α | EM-12 | Multiple myeloma | Thalidomide | Cancer | MULTIPLE-MYELOMA | ACTIVATION | TNF-alpha | ENANTIOMERS | CHEMISTRY, ORGANIC | PHTHALIMIDINE | CYCLOADDITION | ANTIANGIOGENIC ACTIVITY | METABOLISM | CHEMISTRY | DERIVATIVES | Triazoles | Synthesis | Sodium | Phthalimides | Reagents | Coupling | Derivatives | Arrays
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/1999, Volume 163, Issue 1, pp. 380 - 386
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 10/2002, Volume 130, Issue 1, pp. 75 - 84
Thalidomide (Thd) is clinically useful in a number of conditions where its efficacy is probably related to its anti‐TNF ‐α activity. More recently, Thd has... 
immunomodulation | T lymphocyte | co‐stimulation | thalidomide | TNF | Co-stimulation | Immunomodulation | Thalidomide | MULTIPLE-MYELOMA | ACTIVATION | PHASE-II | IMMUNOLOGY | co-stimulation | POTENT INHIBITORS | CC-3052 | INHIBITORY ACTIVITY | IN-VITRO | THERAPY | IMMUNODEFICIENCY-VIRUS INFECTION | APHTHOUS ULCERS | Adjuvants, Immunologic - pharmacology | Antigens, CD - biosynthesis | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Male | Thalidomide - pharmacology | Antigens, CD - genetics | Receptors, Interleukin-2 - genetics | Thalidomide - analogs & derivatives | Neoplasms - therapy | Neoplasms - blood | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | Receptors, Tumor Necrosis Factor, Type II | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Adjuvants, Immunologic - therapeutic use | Receptors, Tumor Necrosis Factor - genetics | Cells, Cultured - drug effects | Enzyme-Linked Immunosorbent Assay | Lenalidomide | Receptors, Interleukin-2 - biosynthesis | Antibodies, Monoclonal - pharmacology | CD4-Positive T-Lymphocytes - metabolism | Solubility | Phosphodiesterase Inhibitors - pharmacology | Inflammation | Antigens, CD - drug effects | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | CD3 Complex - immunology | Lipopolysaccharides - pharmacology | Receptors, Tumor Necrosis Factor - biosynthesis | Aged | Cells, Cultured - metabolism | Thalidomide - therapeutic use | Tumor Necrosis Factor-alpha - biosynthesis | CD4-Positive T-Lymphocytes - drug effects | Receptors, Tumor Necrosis Factor - drug effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Basic Immunology
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2016, Volume 22, Issue 7, pp. 706 - 707
Two recent studies provide novel insights into the mechanism of action of thalidomide analogs in multiple myeloma and del(5q) myelodysplastic syndrome. They... 
TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | DEGRADATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Thalidomide - analogs & derivatives | Humans | Molecular chaperones | Patient outcomes | Genetic aspects | Drug therapy | Thalidomide | Health aspects | Myelodysplastic syndromes | Studies | Calcium | Cancer | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 04/2018, Volume 28, Issue 7, pp. 1223 - 1227
Journal Article
Blood, ISSN 0006-4971, 11/2000, Volume 96, Issue 9, pp. 2943 - 2950
Although thalidomide (Thal) was initially used to treat multiple myeloma (MM) because of its known antiangiogenic effects, the mechanism of its anti-MM... 
APOPTOSIS | ADHESION | ACTIVATION | DEXAMETHASONE |