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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1999, Volume 9, Issue 11, pp. 1625 - 1630
Thalidomide, (1), is a known inhibitor of TNF-α release in LPS stimulated human PBMC. Herein we describe the TNF-α inhibitory activity of amino substituted... 
Thalidomide - analogs & derivatives | Thalidomide - chemical synthesis | Models, Chemical | U937 Cells | Humans | Blood - drug effects | Inhibitory Concentration 50 | Structure-Activity Relationship | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | AIDS/HIV
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2019, Volume 176, pp. 419 - 430
Lenalidomide and its analogs have exhibited extensive anti-tumor, anti-inflammatory and immunomodulatory properties in pharmaceutical research. In this work, a... 
Thioether | Anti-Tumor | Structural modification | Lenalidomide | DEXAMETHASONE | CHEMISTRY, MEDICINAL | NATURAL-KILLER-CELL | THALIDOMIDE | SULFONE | IDENTIFICATION | POTENT INHIBITORS | POMALIDOMIDE | DEGRADATION | T-CELLS | MODULATION | Research institutes | Analysis | Cells | Tumors
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2010, Volume 18, Issue 14, pp. 5379 - 5390
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2015, Volume 71, Issue 42, pp. 8140 - 8149
Herein we describe the synthesis of various simple -alkyl thalidomide derivatives in order to determine their fluorescence excitation and emission profile.... 
Fluorescence | Triazole | Click reaction | Thalidomide | Molecular probes | TARGET | COMPLEX | CHEMISTRY, ORGANIC | TNF EXPRESSION INHIBITION | PROBES | BIOORTHOGONAL REACTIONS | AMINO-ACID | IN-VIVO | Analysis
Journal Article
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 01/2014, Volume 27, Issue 1, pp. 147 - 156
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2019, Volume 34, Issue 1, pp. 1259 - 1270
Pyrazolylphthalimide derivative 4 was synthesized and reacted with different reagents to afford the target compounds imidazopyrazoles 5-7, pyrazolopyrimidines... 
molecular modeling study | drug-likeness | Phthalimide | antimicrobial and anticancer activities | DNA gyrase B | VEGFR-2 | CHEMISTRY, MEDICINAL | MOIETY | BIOCHEMISTRY & MOLECULAR BIOLOGY | THALIDOMIDE | DISCOVERY | HETEROCYCLIC SYNTHESIS | IN-VITRO | PYRAZOLE | ANTIBACTERIAL ACTIVITY | DRUGS | INHIBITORS | DERIVATIVES
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2004, Volume 22, Issue 16, pp. 3269 - 3276
Journal Article
INTERNATIONAL IMMUNOPHARMACOLOGY, ISSN 1567-5769, 08/2014, Volume 21, Issue 2, pp. 283 - 292
Inhibition of angiogenesis is currently perceived as a promising strategy in the treatment of cancer. The anti-angiogenicity of thalidomide has inspired a... 
MULTIPLE-MYELOMA | Thalidomide dithiocarbamate analogs | Migration | VEGF | NECROSIS-FACTOR-ALPHA | CELL-PROLIFERATION | TUMOR ANGIOGENESIS | IMMUNOLOGY | CONGENITAL ABNORMALITIES | Angiogenesis | MATRIX METALLOPROTEINASES | PHASE-II TRIAL | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | TNF-ALPHA | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Archiv der Pharmazie, ISSN 0365-6233, 05/2018, Volume 351, Issue 5, pp. e1700363 - n/a
Journal Article