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Journal Article
American Journal of Therapeutics, ISSN 1075-2765, 2016, Volume 23, Issue 3, pp. e757 - e765
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2010, Volume 38, Issue 1, pp. 92 - 99
The aim of the current study is to identify the human cytochrome P450 (P450) isoforms involved in the two oxidative steps in the bioactivation of clopidogrel... 
MECHANISM-BASED INHIBITION | ANTIAGGREGATING ACTIVITY | POLYMORPHISMS | TICLOPIDINE | PHARMACOKINETICS | HEALTHY-SUBJECTS | PHARMACOLOGY & PHARMACY | PRASUGREL | PHARMACODYNAMICS | MONOCLONAL-ANTIBODIES | ATORVASTATIN | Microsomes - metabolism | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Sulfaphenazole - pharmacology | Microsomes - drug effects | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP1A2 - genetics | Antibodies - immunology | Omeprazole - pharmacology | Microsomes, Liver - enzymology | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Oxidoreductases, N-Demethylating - metabolism | Aryl Hydrocarbon Hydroxylases - immunology | Oxidation-Reduction | Enzyme Inhibitors - pharmacology | Ticlopidine - analogs & derivatives | Oxidoreductases, N-Demethylating - immunology | Cytochrome P-450 CYP3A - metabolism | Cell Line, Tumor | Cytochrome P-450 Enzyme System - genetics | Theophylline - pharmacology | Kinetics | Cytochrome P-450 CYP2C9 | Theophylline - analogs & derivatives | Oxidoreductases, N-Demethylating - genetics | Glutathione - metabolism | Ketoconazole - pharmacology | Biotransformation - physiology | Cytochrome P-450 CYP1A2 Inhibitors | Microsomes, Liver - drug effects | Ticlopidine - metabolism | NADP - metabolism | Platelet Aggregation Inhibitors - metabolism | Cytochrome P-450 CYP3A - immunology | Cell Line | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cytochrome P-450 CYP1A2 - immunology | Biocatalysis | Mephenytoin - analogs & derivatives | Cytochrome P-450 CYP1A2 - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Mephenytoin - pharmacology | Antibodies - pharmacology | Cytochrome P-450 CYP3A Inhibitors | Cytochrome P-450 CYP2C19 | Clopidogrel | Cytochrome P-450 CYP2B6
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 02/2007, Volume 292, Issue 2, pp. G492 - G500
Actions of adenosine 5'-monophosphate (AMP) on electrical and synaptic behavior of submucosal neurons in guinea pig small intestine were studied with "sharp"... 
Enteric nervous system | Gastrointestinal tract | Purinergic receptors | Synaptic transmission | Neurogastroenterology | Norepinephrine - pharmacology | Theophylline - analogs & derivatives | Receptor, Adenosine A1 - physiology | Maleimides - pharmacology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Male | Receptor, Adenosine A2A - physiology | Submucous Plexus - physiology | Adenosine A2 Receptor Antagonists | Excitatory Postsynaptic Potentials - drug effects | Excitatory Postsynaptic Potentials - physiology | Ileum - drug effects | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Indoles - pharmacology | Synaptic Transmission - drug effects | Adenosine Monophosphate - pharmacology | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Submucous Plexus - drug effects | Ileum - innervation | Boron Compounds - pharmacology | Triazines - pharmacology | Guinea Pigs | Phenethylamines - pharmacology | Adenosine A1 Receptor Antagonists | Enzyme Inhibitors - pharmacology | Adenosine - pharmacology | Adenosine Diphosphate - pharmacology | Triazoles - pharmacology | Animals | Signal Transduction - drug effects | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Adenosine - analogs & derivatives | Theophylline - pharmacology | Ileum - physiology | Quinazolines - pharmacology | Adenosine Diphosphate - analogs & derivatives
Journal Article
Pharmacological Research, ISSN 1043-6618, 11/2013, Volume 77, pp. 22 - 29
Journal Article
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 4/2009, Volume 379, Issue 4, pp. 325 - 336
The aim of this study was to investigate the putative influence of some pharmacological agents and drugs of abuse upon the apical uptake of butyrate (BT) into... 
Neurosciences | Biomedicine | Caco-2 cells | Modulation | Pharmacology/Toxicology | Uptake | Butyrate | ULCERATIVE-COLITIS | TISSUE HOMEOSTASIS | COLONIC MONOCARBOXYLATE TRANSPORTER | EPITHELIAL-CELLS | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | CHAIN FATTY-ACIDS | COLORECTAL-CANCER | TUMOR-SUPPRESSOR | PHARMACOLOGY & PHARMACY | RAT DISTAL COLON | DIETARY BIOACTIVE COMPOUNDS | Butyrates - metabolism | Gene Expression - drug effects | Gene Expression - genetics | Humans | Ions - pharmacology | Monocarboxylic Acid Transporters - antagonists & inhibitors | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Symporters - antagonists & inhibitors | Caffeine - pharmacology | Acetaldehyde - pharmacology | Aspirin - pharmacology | Dronabinol - pharmacology | Acids, Acyclic - pharmacology | Caco-2 Cells | Cell Survival - drug effects | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology | Biological Transport, Active - drug effects | Indomethacin - pharmacology | Symporters - genetics | 2,4-Dinitrophenol - pharmacology | 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid - pharmacology | Theophylline - pharmacology | Kinetics | Monocarboxylic Acid Transporters - genetics | Sodium Azide - pharmacology | Hydrogen-Ion Concentration | Lactates | Messenger RNA | Analysis | Ecstasy (Drug) | Illegal drugs | Esters | Universities and colleges | Nonsteroidal anti-inflammatory drugs | Theophylline | Acetaldehyde | Caffeine | Index Medicus
Journal Article
Anaesthesia & Intensive Care Medicine, ISSN 1472-0299, 12/2017, Volume 18, Issue 12, pp. 609 - 613
Knowledge and application of respiratory pharmacology is essential for both anaesthetists and intensive care physicians. Patients often present with... 
respiratory pharmacology | β2-agonists | corticosteroids | bronchodilators | pulmonary hypertension | respiratory physiology | asthma | anticholinergics | acute respiratory distress syndrome (ARDS) | theophyllines | agonists
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2010, Volume 182, Issue 7, pp. 897 - 904
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 10/2011, Volume 38, Issue 10, pp. 658 - 665
1. The present study examined whether or not cilostazol reduces the myocardial infarct size, and investigated its mechanism in a rabbit model of myocardial... 
adenosine | cilostazol | mitochondrial ATP‐sensitive potassium channels | nitric oxide | myocardial infarct size | Adenosine | Cilostazol | Mitochondrial ATP-sensitive potassium channels | Myocardial infarct size | Nitric oxide | ACTIVATION | PHYSIOLOGY | BENIDIPINE | PLATELET-AGGREGATION | SIZE | mitochondrial ATP-sensitive potassium channels | SYNTHASE | PHARMACOLOGY & PHARMACY | RADICALS | PERIPHERAL ARTERIAL-DISEASE | CLAUDICATION | LIMITATION | Theophylline - analogs & derivatives | Hydroxy Acids - pharmacology | Tetrazoles - antagonists & inhibitors | Tetrazoles - pharmacology | Humans | Purinergic P1 Receptor Antagonists - pharmacology | Cardiotonic Agents - therapeutic use | Superoxides - metabolism | Reperfusion Injury - metabolism | Potassium Channel Blockers - pharmacology | Disease Models, Animal | NG-Nitroarginine Methyl Ester - pharmacology | Drug Evaluation, Preclinical - methods | Rabbits | Decanoic Acids - pharmacology | Enzyme Inhibitors - pharmacology | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Animals | Myocardial Infarction - drug therapy | Reperfusion Injury - prevention & control | Adenosine - metabolism | Theophylline - pharmacology | Tetrazoles - therapeutic use | Nitric Oxide - metabolism | Medical colleges | Ischemia | Analysis | Superoxide | Potassium channels | Cardiology | Theophylline | Heart attack
Journal Article
Glia, ISSN 0894-1491, 02/2013, Volume 61, Issue 2, pp. 178 - 191
Heterosynaptic long‐term depression (hLTD) at untetanized synapses accompanying the induction of long‐term potentiation (LTP) spatially sharpens the... 
P2Y receptors | heterosynaptic long‐term depression | astrocytes | ATP | channelrhodopsin‐2 | Channelrhodopsin-2 | Astrocytes | Heterosynaptic long-term depression | STIMULATION | GLUTAMATE RELEASE | SYNAPTIC-TRANSMISSION | CALCIUM WAVES | RECEPTOR | GLIAL-CELLS | NEUROSCIENCES | CULTURED HIPPOCAMPAL-NEURONS | D-SERINE | POTENTIATION | heterosynaptic long-term depression | channelrhodopsin-2 | PLASTICITY | Glial Fibrillary Acidic Protein - genetics | Theophylline - analogs & derivatives | Electric Stimulation | Calcium - metabolism | Embryo, Mammalian | Calcium Signaling - physiology | Channelrhodopsins | Green Fluorescent Proteins - genetics | Long-Term Synaptic Depression - drug effects | Glial Fibrillary Acidic Protein - metabolism | Excitatory Postsynaptic Potentials - drug effects | Purinergic P1 Receptor Antagonists - pharmacology | Adenosine Triphosphate - pharmacology | Excitatory Postsynaptic Potentials - physiology | Transfection | Time Factors | Adenosine Triphosphate - metabolism | Neurons - physiology | Astrocytes - chemistry | Neurons - drug effects | Purinergic P2Y Receptor Antagonists - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Proteoglycans - metabolism | Rats | Antigens - metabolism | Optical Phenomena | Adenosine - pharmacology | Biophysics | Hippocampus - cytology | Adenosine Diphosphate - pharmacology | Patch-Clamp Techniques | Animals | Serine - pharmacology | Theophylline - pharmacology | Genetic Vectors - physiology | Mice | In Vitro Techniques | Adenosine Diphosphate - analogs & derivatives | Astrocytes - metabolism | Methyl aspartate | Neurosciences | Depression, Mental
Journal Article