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Endocrine, metabolic & immune disorders drug targets, ISSN 1871-5303, 2006
Journal
Inflammation & allergy, ISSN 1871-5281, 2006
Journal
Expert opinion on therapeutic targets, ISSN 1472-8222, 2001
Journal
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2017, Volume 70, Issue 18, pp. 2278 - 2289
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 12/2006, Volume 5, Issue 12, pp. 993 - 996
For the past decade, the number of molecular targets for approved drugs has been debated. Here, we reconcile apparently contradictory previous reports into a... 
Technology, Pharmaceutical | Humans | Drug Design | Drugs, Investigational - therapeutic use | Drug Approval | Drug Delivery Systems - trends | Genome, Human | Pharmaceutical industry
Journal Article
2006, 1. Aufl., Ernst Schering Research Foundation Workshop, ISBN 3540254277, Volume 56, Issue 2, xvii, 209
Book
Cardiovascular & hematological disorders drug targets, ISSN 1871-529X, 2006
Journal
Molecular systems biology, ISSN 1744-4292, 2017, Volume 13, Issue 3, pp. 916 - n/a
To elucidate the molecular mechanisms underlying non-alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis... 
serine | NAFLD | personalized genome‐scale metabolic modeling | glutathione | personalized genome-scale metabolic modeling | FATTY LIVER-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUSCLE | DRUG TARGETS | CANCER | AMINO-ACID-METABOLISM | HEPATOCELLULAR-CARCINOMA | INSULIN-RESISTANCE | ADIPOSE-TISSUE | GENOME-SCALE | REVEALS | Glycine - blood | Liver - enzymology | Non-alcoholic Fatty Liver Disease - genetics | Glutathione - metabolism | Serine - blood | Humans | Liver - metabolism | Middle Aged | Male | Non-alcoholic Fatty Liver Disease - metabolism | Patient-Specific Modeling | Metabolomics - methods | Gene Expression Regulation, Enzymologic | Serine - administration & dosage | Animals | Lipoproteins - metabolism | Female | Mice | Non-alcoholic Fatty Liver Disease - diet therapy | Genome | NAD - metabolism | Serine - therapeutic use | Disease Models, Animal | Genomes | Metabolites | Metabolism | Liver | Rodents | Serine | Lipids | Biosynthesis | Glycine | Body mass index | Fatty liver | Precursors | Supplementation | Glutathione | Level (quantity) | Liver diseases | Fasting | Demand analysis | Dietary supplements | Triglycerides | Fluxes | Apolipoproteins | Gene expression | Cholesterol | Steatosis | NAD | Molecular modelling | Insulin resistance | Plasma levels | Laboratory animals | Life Sciences | Biochemistry, Molecular Biology | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article