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1. Full Text Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity
by Jia, Ning and Mo, Charlie Y and Wang, Chongyuan and Eng, Edward T and Marraffini, Luciano A and Patel, Dinshaw J
Molecular cell, ISSN 1097-2765, 01/2019, Volume 73, Issue 2, pp. 264 - 277.e5
ternary complex assembly with crRNA and target RNA | type III-A CRISPR-Cas complexes | 5′ repeat tag pairing controls autoimmunity | DNase activity regulation by Glu residues | T. onnurineus Csm | RNA cleavage with 6-nt periodicity | cryo-EM | T. onnurineus Csm | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Autoimmunity | RNA-Binding Proteins - genetics | Thermococcus - genetics | Multiprotein Complexes | Deoxyribonucleases - ultrastructure | Structure-Activity Relationship | CRISPR-Associated Proteins - ultrastructure | Deoxyribonucleases - metabolism | Deoxyribonucleases - immunology | Thermococcus - enzymology | Thermococcus - immunology | RNA, Bacterial - genetics | Bacterial Proteins - immunology | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Clustered Regularly Interspaced Short Palindromic Repeats - immunology | Nucleic Acid Conformation | RNA, Bacterial - ultrastructure | RNA, Bacterial - metabolism | CRISPR-Associated Proteins - immunology | Escherichia coli - enzymology | CRISPR-Cas Systems - immunology | CRISPR-Associated Proteins - genetics | RNA-Binding Proteins - immunology | Bacterial Proteins - genetics | Escherichia coli - immunology | Models, Molecular | RNA Stability | CRISPR-Cas Systems - genetics | Cryoelectron Microscopy | RNA-Binding Proteins - ultrastructure | Deoxyribonucleases - genetics | Escherichia coli - genetics | CRISPR-Associated Proteins - metabolism | RNA, Bacterial - immunology | Bacterial Proteins - metabolism | Protein Conformation | Bacterial Proteins - ultrastructure | Mutation | Gene Expression Regulation, Bacterial | RNA-Binding Proteins - metabolism | Index Medicus
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2. Full Text The structure of the Thermococcus gammatolerans McrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs
by Hosford, Christopher J and Bui, Anthony Q and Chappie, Joshua S and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
The Journal of biological chemistry, ISSN 0021-9258, 01/2020, Volume 295, Issue 3, pp. 743 - 756
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | DNA Restriction Enzymes - chemistry | Protein Binding - genetics | DNA Restriction Enzymes - genetics | Substrate Specificity | Crystallography, X-Ray | Escherichia coli Proteins - ultrastructure | DNA Methylation - genetics | Amino Acid Sequence - genetics | Binding Sites - genetics | DNA-Binding Proteins - genetics | Escherichia coli - chemistry | RNA - chemistry | DNA-Binding Proteins - chemistry | Protein Domains - genetics | RNA - genetics | DNA-Binding Proteins - ultrastructure | DNA Mutational Analysis | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Protein Conformation | Thermococcus | DNA Restriction Enzymes - ultrastructure | Escherichia coli Proteins - chemistry | Index Medicus | protein-nucleic acid interaction | McrB | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY | BASIC BIOLOGICAL SCIENCES | DNA binding protein | RNA-protein interaction | DNA binding | X-ray crystallography | protein structure | restriction system | structural biology | YTH domain | 6-methyladenosine
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3. Full Text Primary transcriptome map of the hyperthermophilic archaeon Thermococcus kodakarensis
by Jäger, Dominik and Förstner, Konrad U and Sharma, Cynthia M and Santangelo, Thomas J and Reeve, John N
BMC genomics, ISSN 1471-2164, 2014, Volume 15, Issue 1, pp. 684 - 684
Hyperthermophile | Riboswitch | Hydrogen regulation | Antisense RNAs | Archaea | Transcriptome | Small non-coding RNAs | Promoters | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Thermococcus - genetics | Base Sequence | Transcription Initiation Site | RNA, Small Untranslated - genetics | Transcription, Genetic | 5' Untranslated Regions - genetics | Gene Expression Profiling | Promoter Regions, Genetic - genetics | RNA, Antisense - genetics | RNA sequencing | Messenger RNA | Genomic libraries | Genetic transcription | Analysis | Genes | Automation | Databases | Genomics | Colleges & universities | Expected values | Information storage | Genomes | Metabolism | Gene expression | Academic libraries | Index Medicus
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4. Full Text Enhanced detection of RNA by MMLV reverse transcriptase coupled with thermostable DNA polymerase and DNA/RNA helicase
by Okano, Hiroyuki and Katano, Yuta and Baba, Misato and Fujiwara, Ayako and Hidese, Ryota and Fujiwara, Shinsuke and Yanagihara, Itaru and Hayashi, Tsukasa and Kojima, Kenji and Takita, Teisuke and Yasukawa, Kiyoshi
Enzyme and microbial technology, ISSN 0141-0229, 01/2017, Volume 96, pp. 111 - 120
Helicase | Taguchi’s method | Reverse transcriptase | DNA polymerase | cDNA synthesis | Taguchi's method | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Recombinant Proteins - metabolism | Moloney murine leukemia virus - genetics | Gene Expression | Temperature | Oligonucleotide Array Sequence Analysis | RNA - analysis | RNA-Directed DNA Polymerase - metabolism | Thermococcus - genetics | DNA, Complementary - genetics | Enzyme Stability | Recombinant Proteins - genetics | DNA-Directed DNA Polymerase - genetics | RNA - genetics | Thermococcus - enzymology | Base Sequence | Protein Engineering | RNA-Directed DNA Polymerase - genetics | DNA, Complementary - biosynthesis | RNA Helicases - genetics | DNA-Directed DNA Polymerase - metabolism | Gram-Negative Anaerobic Straight, Curved, and Helical Rods - enzymology | Gram-Negative Anaerobic Straight, Curved, and Helical Rods - genetics | DNA Helicases - genetics | Moloney murine leukemia virus - enzymology | DNA polymerases | Enzymes | RNA | DNA | Leukemia | Genetically modified organisms | Genetic research | Genetic engineering | Gene expression | Index Medicus
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5. Full Text Genetic manipulations of the hyperthermophilic piezophilic archaeon Thermococcus barophilus
by Thiel, Axel and Michoud, Grégoire and Moalic, Yann and Flament, Didier and Jebbar, Mohamed
Applied and environmental microbiology, ISSN 0099-2240, 2014, Volume 80, Issue 7, pp. 2299 - 2306
Life Sciences & Biomedicine | Microbiology | Biotechnology & Applied Microbiology | Science & Technology | Transformation, Genetic | Mutagenesis, Insertional - methods | Plasmids | Thermococcus - genetics | Gene Deletion | Selection, Genetic | Genetics, Microbial - methods | Molecular Biology - methods | Gene Knockout Techniques - methods | Influence | Thermococcus | Genetic engineering | Genetic aspects | Research | Simvastatin | Genetics | Mutation | Gram-negative bacteria | Cells | Index Medicus | Life Sciences | Genetics and Molecular Biology
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6. Full Text Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea
by Zivanovic, Yvan and Armengaud, Jean and Lagorce, Arnaud and Leplat, Christophe and Guérin, Philippe and Dutertre, Murielle and Anthouard, Véronique and Forterre, Patrick and Wincker, Patrick and Confalonieri, Fabrice
Genome Biology, ISSN 1474-7596, 06/2009, Volume 10, Issue 6, pp. R70 - R70
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Gamma Rays | Proteome - genetics | Codon, Initiator - genetics | Thermococcus - genetics | Thermococcus - virology | DNA Repair - radiation effects | Radiation Tolerance - radiation effects | Hydrogenase - metabolism | Biological Transport - radiation effects | Mass Spectrometry | DNA Transposable Elements - genetics | Chromosomes - metabolism | Protein Biosynthesis - genetics | Microbial Viability - radiation effects | Protein Biosynthesis - radiation effects | Cell Membrane - radiation effects | Archaeal Proteins - metabolism | Reproducibility of Results | Thermococcus - growth & development | Protein Processing, Post-Translational - radiation effects | Radiation Tolerance - genetics | Sequence Analysis, DNA | Cell Membrane - enzymology | Genome, Archaeal - genetics | Proteomics | Thermococcus - metabolism | Index Medicus | Life Sciences | Microbiology and Parasitology | Biochemistry, Molecular Biology | Research
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7. Full Text Genetics techniques for Thermococcus kodakarensis
by Hileman, Travis H and Santangelo, Thomas J
Frontiers in microbiology, ISSN 1664-302X, 2012, Volume 3, pp. 195 - 195
Thermococcales | Genetics | Recombination | Transcription | Hyperthermophilic | Archaea | Life Sciences & Biomedicine | Microbiology | Science & Technology | Hyperthermophile | Thermococcus | recombination
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8. Full Text Improved and Versatile Transformation System Allowing Multiple Genetic Manipulations of the Hyperthermophilic Archaeon Thermococcus kodakaraensis
by Takaaki Sato and Toshiaki Fukui and Haruyuki Atomi and Tadayuki Imanaka
Applied and Environmental Microbiology, ISSN 0099-2240, 07/2005, Volume 71, Issue 7, pp. 3889 - 3899
Life Sciences & Biomedicine | Microbiology | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Miscellaneous | Methods. Procedures. Technologies | Genetic technics | Biological and medical sciences | Genetics | Genetic engineering | Bacteriology | Synthetic digonucleotides and genes. Sequencing | Archaeal Proteins - metabolism | Genetic Engineering - methods | Transformation, Genetic | Thermococcus - growth & development | Recombination, Genetic | Thermococcus - genetics | Gene Deletion | Archaeal Proteins - genetics | Genetic Markers | Hot Temperature | Genetic Vectors | Mutation | Index Medicus | Methods
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9. Full Text Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes
by Fukui, Toshiaki and Atomi, Haruyuki and Kanai, Tamotsu and Matsumi, Rie and Fujiwara, Shinsuke and Imanaka, Tadayuki
Genome research, ISSN 1088-9051, 03/2005, Volume 15, Issue 3, pp. 352 - 363
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Archaeal Proteins - metabolism | Pyrococcus abyssi - genetics | Thermococcus - genetics | Genome, Archaeal | Pyrococcus - metabolism | Archaeal Proteins - chemistry | Chromosome Mapping | Pyrococcus horikoshii - genetics | Nucleotides - metabolism | Pyrococcus furiosus - genetics | Amino Acids - metabolism | Coenzymes - metabolism | Energy Metabolism | Models, Biological | Archaeal Proteins - genetics | Pyrococcus - genetics | Thermococcus - metabolism | Amino Acid Substitution | Index Medicus
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10. Full Text Mutation design of a thermophilic Rubisco based on three‐dimensional structure enhances its activity at ambient temperature
by Fujihashi, Masahiro and Nishitani, Yuichi and Kiriyama, Tomohiro and Aono, Riku and Sato, Takaaki and Takai, Tomoyuki and Tagashira, Kenta and Fukuda, Wakao and Atomi, Haruyuki and Imanaka, Tadayuki and Miki, Kunio
Proteins, structure, function, and bioinformatics, ISSN 0887-3585, 10/2016, Volume 84, Issue 10, pp. 1339 - 1346
crystal structure | protein engineering | ribulose‐1,5‐bisphosphate carboxylase/oxygenase | protein‐ligand complex | carbon dioxide fixation | protein-ligand complex | ribulose-1,5-bisphosphate carboxylase/oxygenase | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Rhodopseudomonas - chemistry | Thermococcus - genetics | Rhodopseudomonas - genetics | Archaeal Proteins - chemistry | Bacterial Proteins - chemistry | Ribulose-Bisphosphate Carboxylase - genetics | Crystallography, X-Ray | Structure-Activity Relationship | Thermococcus - enzymology | Plant Proteins - chemistry | Spinacia oleracea - genetics | Cloning, Molecular | Escherichia coli - metabolism | Protein Engineering | Archaeal Proteins - genetics | Plant Proteins - metabolism | Archaeal Proteins - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence |