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Journal of Controlled Release, ISSN 0168-3659, 11/2015, Volume 217, pp. 243 - 255
Macrophages are innate immune cells with great phenotypic plasticity, which allows them to regulate an array of physiological processes such as host defense,... 
Obesity | Theranostic nanoparticles | Intravital imaging | Inflammation | Magnetic resonance imaging | Atherosclerosis | CORE-SHELL NANOPARTICLES | ATHEROSCLEROTIC PLAQUES | CONTRAST AGENTS | DRUG-DELIVERY | PHOSPHOLIPASE A | CHEMISTRY, MULTIDISCIPLINARY | ENDOTHELIAL-CELLS | INTRACELLULAR DELIVERY | PPAR-GAMMA | PHARMACOLOGY & PHARMACY | EXPRESSION | ADIPOSE-TISSUE | Nanoparticles - chemistry | Obesity - immunology | Polyethylene Glycols - chemistry | Thiazolidinediones - chemistry | Thiazolidinediones - administration & dosage | Tamoxifen - administration & dosage | Polystyrenes - chemistry | Cholesterol - chemistry | Paclitaxel - chemistry | Fluorescein-5-isothiocyanate - chemistry | Tamoxifen - chemistry | Anti-Inflammatory Agents - administration & dosage | Paclitaxel - administration & dosage | Cytokines - genetics | Macrophages - immunology | Phospholipases A2 - chemistry | Cell Line | Cholesterol - analogs & derivatives | Atherosclerosis - immunology | Mice, Inbred C57BL | Phosphatidylserines - chemistry | Gadolinium - chemistry | Mice, Knockout | Animals | Anti-Inflammatory Agents - chemistry | Apolipoproteins E - genetics | Macrophages - drug effects | Nanoparticles - administration & dosage | Phosphatidylethanolamines - chemistry | Phagocytosis | Nanoparticles | Drugs | Drug delivery systems | Physiological aspects | Lipids | Macrophages | Vehicles | Fluorescein | Cardiovascular agents | Index Medicus
Journal Article
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 10/2011, Volume 76, Issue 20, pp. 8262 - 8269
A POCl3-mediated, direct amination reaction of heterocyclic amides/ureas with NH-heterocycles or N-substituted anilines is described. Compared to the existing... 
FUNCTIONALIZATION | FACILE SYNTHESIS | ACID | LIGANDS | AMINO | CUI | ARYLATION | CHEMISTRY, ORGANIC | ARYL | INHIBITORS | PALLADIUM-CATALYZED AMINATION | Azabicyclo Compounds - analysis | Erlotinib Hydrochloride | Hypnotics and Sedatives - chemistry | Chemistry, Pharmaceutical - methods | Humans | Hypnotics and Sedatives - analysis | Hypoglycemic Agents - analysis | Anticholesteremic Agents - chemistry | Heterocyclic Compounds - chemical synthesis | Piperazines - chemistry | Fluorobenzenes - chemistry | Thiazolidinediones - chemistry | Eszopiclone | Azabicyclo Compounds - chemistry | Pyrimidines - chemistry | Urea - chemistry | Prescription Drugs - analysis | Protein Kinase Inhibitors - chemistry | Thiazolidinediones - analysis | Amination | Protein Kinase Inhibitors - analysis | Urea - analogs & derivatives | Anticholesteremic Agents - analysis | Molecular Structure | Catalysis | Quinazolines - chemistry | Quinazolines - analysis | Pyrimidines - analysis | Sulfonamides - analysis | Sulfonamides - chemistry | Rosuvastatin Calcium | Hypoglycemic Agents - chemistry | Imatinib Mesylate | Phosphorus Compounds - chemistry | Heterocyclic Compounds - analysis | Piperazines - analysis | Amides - chemistry | Prescription Drugs - chemical synthesis | Aniline Compounds - chemistry | Benzamides | Fluorobenzenes - analysis | Hydrogen-Ion Concentration | Index Medicus
Journal Article
Lipids in Health and Disease, ISSN 1476-511X, 01/2017, Volume 16, Issue 1, pp. 17 - 17
Background: PPAR gamma is an isoform of peroxisome proliferator-activated receptor (PPAR) belonging to a super family of nuclear receptors. PPAR gamma receptor... 
Docking | Helix12 | Bioactive lipids | PUFA | PPARγ | PARTIAL AGONISTS | MOLECULAR-DYNAMICS | DOMAIN | PROLIFERATOR-ACTIVATED RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | PPAR gamma | NUTRITION & DIETETICS | PROSTATE-CANCER | LIGAND | DYSLIPIDEMIA | PROGRESSION | LIPIDS | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e38546 - e38546
Owing to their unique functions in regulating glucose, lipid and cholesterol metabolism, PPARs (peroxisome proliferator-activated receptors) have drawn special... 
BIOLOGICAL FUNCTIONS | MOLECULAR-DYNAMICS | COLLECTIVE MOTION | 3D STRUCTURE | FREQUENCY VIBRATIONS PHONONS | MULTIDISCIPLINARY SCIENCES | PROTEASE CLEAVAGE SITES | PPAR-GAMMA | FATTY-ACIDS | LIGAND-BINDING DOMAIN | ALLOSTERIC TRANSITION | Hypoglycemic Agents - therapeutic use | Protein Structure, Tertiary | Hypoglycemic Agents - pharmacokinetics | Humans | Molecular Conformation | Oxazoles - pharmacokinetics | Models, Molecular | Hypoglycemic Agents - chemistry | Tyrosine - analogs & derivatives | Molecular Dynamics Simulation | Oxazoles - chemistry | Tyrosine - therapeutic use | Drug Design | PPAR gamma - agonists | Ligands | PPAR alpha - agonists | Molecular Structure | Tyrosine - pharmacokinetics | Diabetes Mellitus, Type 2 - drug therapy | Binding Sites | Oxazoles - therapeutic use | PPAR alpha - chemistry | Tyrosine - chemistry | PPAR gamma - chemistry | Type 2 diabetes | Molecular dynamics | Physiological aspects | Methods | Diabetes therapy | Drugs | Disease | Molecular structure | Laboratories | Drug development | Phosphatase | Proteins | Glucose metabolism | Receptors | Illnesses | Tempering | Docking | Life sciences | Lipid metabolism | Hypertension | Obesity | Excretion | Computer simulation | Diabetes mellitus | Lead compounds | Metabolism | Fatty acids | Cholesterol | Cores | Side effects | Mutagenesis | Pharmacy | Computer applications | Strategy | Insulin resistance | Peroxisome proliferator-activated receptors | Diabetes | Thiazolidinediones | Conformation | Index Medicus
Journal Article
Journal Article
Chemical research in toxicology, ISSN 0893-228X, 09/2012, Volume 25, Issue 9, pp. 1938 - 1947
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2010, Volume 53, Issue 18, pp. 6584 - 6594
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 04/2012, Volume 22, Issue 8, pp. 2720 - 2722
Journal Article