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1. Full Text Convergent Chemical Synthesis of Proteins by Ligation of Peptide Hydrazides
by Fang, Ge‐Min and Wang, Jia‐Xing and Liu, Lei
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2012, Volume 51, Issue 41, pp. 10347 - 10350
Coming together: A generally applicable strategy for convergent chemical synthesis of proteins from multiple peptide segments is developed on the basis of the... 
peptides | protecting groups | total synthesis | proteins | synthesis design | ERYTHROPOIETIN | X-RAY-STRUCTURE | CYSTEINE | S ACYL SHIFT | THIOESTER | CHEMISTRY, MULTIDISCIPLINARY | STRATEGIES | O-ESTERS | KINETICALLY CONTROLLED LIGATION | GLYCOPROTEIN | BOND | Ribosomal Proteins - chemistry | Amino Acid Sequence | Hydrazines - chemistry | Ribosomal Proteins - chemical synthesis | Peptides - chemical synthesis | Humans | Research Design | Thiazolidines - chemistry | Proteins | Synthesis | Magnetic fields | Organic compounds | Peptides | Low cost | Strategy | Segments | Hydrazides
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2. Full Text Chemical Synthesis of Heterocyclic−Sugar Nucleoside Analogues
by Romeo, Giovanni and Chiacchio, Ugo and Corsaro, Antonino and Merino, Pedro
Chemical Reviews, ISSN 0009-2665, 06/2010, Volume 110, Issue 6, pp. 3337 - 3370
HEPATITIS-B-VIRUS | ANTI-HIV ACTIVITY | HUMAN DEOXYCYTIDINE KINASE | POTENT ANTIVIRAL AGENT | DIELS-ALDER REACTIONS | BIOLOGICAL EVALUATION | HUMAN-IMMUNODEFICIENCY-VIRUS | N-RIBOSIDE HYDROLASES | TRANSITION-STATE ANALOG | CHEMISTRY, MULTIDISCIPLINARY | L-DIOXOLANE-CYTIDINE | Nucleosides - chemistry | Nucleosides - chemical synthesis | Carbohydrates - chemistry | Heterocyclic Compounds - chemistry | Sulfides - chemistry | Heterocyclic Compounds - chemical synthesis | Sulfhydryl Compounds - chemistry | Isoxazoles - chemistry | Dioxolanes - chemistry | Pyrrolidines - chemistry | Oxazoles - chemistry | Thiazolidines - chemistry | Chemical properties | Chemical synthesis | Structure | Heterocyclic compounds | Analysis | Nucleoside analogs
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3. Full Text A novel ring opening reaction of peptide N-terminal thiazolidine with 2,2′-dipyridyl disulfide (DPDS) efficient for protein chemical synthesis
by Katayama, Hidekazu and Morisue, Satoki
Tetrahedron, ISSN 0040-4020, 06/2017, Volume 73, Issue 25, pp. 3541 - 3547
In the protein chemical synthesis via native chemical ligation (NCL) method with three peptide segments, the N-terminal cysteine residue of middle segment is... 
Native chemical ligation | 2,2′-dipyridyl disulfide | Deprotection | Thiazolidine | ERYTHROPOIETIN | 2,2 '-dipyridyl disulfide | LIGATION | CONVERGENT | CHEMISTRY, ORGANIC | CYSTEINE | GLYCOFORM | H2B | Cysteine | Peptides | Chemical synthesis | Cystine
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4. Full Text Synthesis of New 4‑Thiazolidinone‑, Pyrazoline‑, and Isatin-Based Conjugates with Promising Antitumor Activity
by Havrylyuk, Dmytro and Zimenkovsky, Borys and Vasylenko, Olexandr and Gzella, Andrzej and Lesyk, Roman
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 20, pp. 8630 - 8641
The synthesis and antitumor activity screening of novel... 
DESIGN | CHEMISTRY, MEDICINAL | ANTICANCER ACTIVITY EVALUATION | AGENTS | INHIBITORS | IDENTIFICATION | DERIVATIVES | BINDING | DISCOVERY | MOLECULES | HISTORY | Thiazolidines - chemical synthesis | Pyrazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Isatin - pharmacology | Structure-Activity Relationship | Isatin - chemistry | Antineoplastic Agents - chemistry | Isatin - analogs & derivatives | Pyrazoles - chemistry | Isatin - chemical synthesis | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Thiazolidines - pharmacology | Thiazolidines - chemistry | Drug Screening Assays, Antitumor | Pyrazoles - pharmacology
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5. Full Text 4-Thiazolidinones: The advances continue
by Tripathi, Avinash C and Gupta, Shiv Ji and Fatima, Gul Naz and Sonar, Pankaj Kumar and Verma, Amit and Saraf, Shailendra K
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2014, Volume 72, pp. 52 - 77
The diversity in the biological response of 4-thiazolidinones has attracted the attention of many researchers to explore this framework for its potential. It... 
Antimicrobial | Cardiovascular | NSAID | Antidiabetic | Anticonvulsant | Stereochemistry | Thiazolidin-4-ones | Synthesis and characterization | Antituberculosis | Antiviral | Antihyperlipidemic | Antiparasitic | Anticancer | Patents on 4-thiazolidinones | TYROSINE-PHOSPHATASE B | CALCIUM OVERLOAD INHIBITION | ONE-POT SYNTHESIS | ANTI-HIV AGENTS | ANTICONVULSANT ACTIVITY | BIOLOGICAL EVALUATION | MICROWAVE-ASSISTED SYNTHESIS | CHEMISTRY, MEDICINAL | ALDOSE REDUCTASE INHIBITORS | GRAM-NEGATIVE BACTERIA | FOLLICLE-STIMULATING-HORMONE | Antihypertensive Agents - pharmacology | Thiazolidines - chemical synthesis | Anticonvulsants - chemical synthesis | Stereoisomerism | Anti-Infective Agents - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Hypoglycemic Agents - chemistry | Antihypertensive Agents - chemical synthesis | Antineoplastic Agents - chemistry | Anticonvulsants - pharmacology | Anti-Infective Agents - chemical synthesis | Hypoglycemic Agents - pharmacology | Antihypertensive Agents - chemistry | Animals | Anti-Infective Agents - chemistry | Anticonvulsants - chemistry | Hypoglycemic Agents - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Thiazolidines - pharmacology | Thiazolidines - chemistry | Trademarks | Drugstores
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6. Full Text Palladium Mediated Rapid Deprotection of N‑Terminal Cysteine under Native Chemical Ligation Conditions for the Efficient Preparation of Synthetically Challenging Proteins
by Jbara, Muhammad and Maity, Suman Kumar and Seenaiah, Mallikanti and Brik, Ashraf
Journal of the American Chemical Society, ISSN 0002-7863, 04/2016, Volume 138, Issue 15, pp. 5069 - 5075
Facilitating the process of chemical protein synthesis is an important goal in order to enable the efficient preparation of large and novel protein analogues.... 
Molecular Sequence Data | Amino Acid Sequence | Cysteine - chemistry | Proteins - chemical synthesis | Palladium - chemistry | Thiazolidines - chemistry | Proteins | Palladium | Chemical properties | Research | Chemical synthesis
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7. Full Text Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins
by Jbara, Muhammad and Laps, Shay and Morgan, Michael and Kamnesky, Guy and Mann, Guy and Wolberger, Cynthia and Brik, Ashraf
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3154 - 11
Organic chemistry allows for the modification and chemical preparation of protein analogues for various studies. The thiolate side chain of the Cys residue has... 
DEHYDROALANINE | ERYTHROPOIETIN | HISTONE H2A | PEPTIDES | MULTIDISCIPLINARY SCIENCES | NATIVE CHEMICAL LIGATION | PURIFICATION | DESULFURIZATION | PROTECTING GROUPS | DEPROTECTION | PROBES | Amino Acid Sequence | Nucleosomes - chemistry | Histones - chemical synthesis | Cysteine - chemistry | Amino Acids | Copper - chemistry | Staining and Labeling | Ubiquitinated Proteins - chemical synthesis | Deubiquitinating Enzymes - metabolism | Protein Processing, Post-Translational | Proteins - chemical synthesis | Palladium - chemistry | Thiazolidines - chemistry | Enzymes | Histone H2A | Peptides | Amino acids | Protein biosynthesis | Palladium | Proteins | Organic chemistry | Protein synthesis | Protecting groups | Nucleosomes | Coordination compounds | Chemical synthesis
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8. Full Text Efficient microwave enhanced regioselective synthesis of a series of benzimidazolyl/triazolyl spiro [indole-thiazolidinones] as potent antifungal agents and crystal structure of spiro[3 H -indole-3,2′-thiazolidine]-3′(1,2,4-triazol-3-yl)-2,4′(1 H )-dione
by Dandia, Anshu and Singh, Ruby and Khaturia, Sarita and Mérienne, Claude and Morgant, Georges and Loupy, André
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2006, Volume 14, Issue 7, pp. 2409 - 2417
A microwave-assisted three-component, regioselective one-pot synthesis of spiro[indole-thiazolidinones] ( – ) is carried out using montmorillonite KSF as solid... 
DRY-MEDIA SYNTHESIS | ORGANIC-SYNTHESIS | SPIROHETEROCYCLES | ACTIVATION | 4-THIAZOLIDINONES | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIMICROBIAL AGENTS | CHEMISTRY, ORGANIC | IRRADIATION | 3-COMPONENT CONDENSATION | INHIBITORS | DERIVATIVES | Colletotrichum - drug effects | Stereoisomerism | Triazoles - chemistry | Indoles - chemical synthesis | Fusarium - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Benzimidazoles - chemistry | Thiazolidines | X-Ray Diffraction | Spiro Compounds - chemical synthesis | Indoles - pharmacology | Molecular Structure | Triazoles - radiation effects | Microwaves | Spiro Compounds - chemistry | Antifungal Agents - pharmacology | Indoles - radiation effects | Crystallization | Models, Molecular | Benzimidazoles - radiation effects | Rhizoctonia - classification | Thiazoles - radiation effects | Rhizoctonia - drug effects | Colletotrichum - classification | Thiazoles - chemistry | Fusarium - classification | Indoles - chemistry | Spiro Compounds - pharmacology | Clay | Montmorillonite | Structure | Crystals | Antifungal agents
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9. Full Text An asymmetric alkynylation/hydrothiolation cascade: an enantioselective synthesis of thiazolidine-2-imines from imines, acetylenes and isothiocyanates
by Ranjan, Alok and Mandal, Anupam and Yerande, Swapnil G and Dethe, Dattatraya H
Chemical communications (Cambridge, England), ISSN 1359-7345, 09/2015, Volume 51, Issue 75, pp. 14215 - 14218
A multicomponent reaction between imines, terminal alkynes, and isothiocyanates in the presence of a catalytic chiral copper-pybox complex proceeds... 
Thiazolidines - chemical synthesis | Isothiocyanates - chemistry | Stereoisomerism | Imines - chemistry | Alkynes - chemistry | Molecular Structure | Imines - chemical synthesis | Alkylation | Thiazolidines - chemistry
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10. Full Text 2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents
by Azizmohammadi, Mohammad and Khoobi, Mehdi and Ramazani, Ali and Emami, Saeed and Zarrin, Abdolhossein and Firuzi, Omidreza and Miri, Ramin and Shafiee, Abbas
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2013, Volume 59, pp. 15 - 22
A variety of ( )-[(2 -chromen-3-yl)methylene]azolidinones – bearing thiazolidine-2,4-dione, rhodanine or hydantoin scaffolds were designed and synthesized as... 
Rhodanine | Cytotoxicity | Anti-cancer agents | 2H-chromene | Thiazolidine-2,4-dione | Hydantoin | GAMMA | 5-BENZYLIDENE-HYDANTOINS | APOPTOSIS | ANTIPROLIFERATIVE ACTIVITY | CHEMISTRY, MEDICINAL | PROLIFERATION | CYTOTOXIC ACTIVITY | IN-VITRO | PROSTATE-CANCER CELLS | INHIBITORS | THIAZOLIDINEDIONES | Cell Survival - drug effects | Thiazolidines - chemical synthesis | Hydantoins - pharmacology | Rhodanine - chemical synthesis | Rhodanine - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Benzopyrans - chemistry | Benzopyrans - chemical synthesis | Animals | Rhodanine - pharmacology | Cell Line, Tumor | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Mice | Benzopyrans - pharmacology | Hydantoins - chemistry | Thiazolidines - pharmacology | Thiazolidines - chemistry | Hydantoins - chemical synthesis | Antimitotic agents | Care and treatment | Universities and colleges | Antineoplastic agents | Cancer
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11. Full Text Bisphosphine-Catalyzed Mixed Double-Michael Reactions:  Asymmetric Synthesis of Oxazolidines, Thiazolidines, and Pyrrolidines
by Sriramurthy, Vardhineedi and Barcan, Gregg A and Kwon, Ohyun
Journal of the American Chemical Society, ISSN 0002-7863, 10/2007, Volume 129, Issue 43, pp. 12928 - 12929
Bisphosphine-catalyzed mixed double-Michael reactions have been developed to afford β-amino carbonyl derivatives of oxazolidines, thiozolidines, and... 
ORGANIC-SYNTHESIS | 4+2 ANNULATION | PHOSPHINE | LIGANDS | HETEROCYCLES | RINGS | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | ALKYNONES | CONJUGATE ADDITION | ALKALOIDS | Oxazoles - chemical synthesis | Phosphines - chemistry | Thiazolidines - chemical synthesis | Pyrrolidines - chemical synthesis | Stereoisomerism | Molecular Structure | Catalysis | Pyrrolidines - chemistry | Oxazoles - chemistry | Thiazolidines - chemistry | Nuclear magnetic resonance spectroscopy | Analysis
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12. Full Text Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes
by Donohoe, Timothy J and Kabeshov, Mikhail A and Rathi, Akshat H and Smith, Ian E D
Organic & biomolecular chemistry, ISSN 1477-0520, 02/2012, Volume 10, Issue 5, pp. 1093 - 1101
A range of heterocycles, namely thiazoles, imidazoles, imidazopyridines, thiazolidines and dimethoxyindoles, have been synthesised directly from alkenes via a... 
Alkenes - chemistry | Thiazolidines - chemical synthesis | Cyclization | Thiazoles - chemical synthesis | Pyridines - chemistry | Imidazoles - chemistry | Pyridines - chemical synthesis | Thiazoles - chemistry | Imidazoles - chemical synthesis | Alkenes - chemical synthesis | Thiazolidines - chemistry
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13. Full Text Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase
by Zidar, Nace and Tomašić, Tihomir and Šink, Roman and Rupnik, Veronika and Kovač, Andreja and Turk, Samo and Patin, Delphine and Blanot, Didier and Contreras Martel, Carlos and Dessen, Andréa and Müller Premru, Manica and Zega, Anamarija and Gobec, Stanislav and Peterlin Mašič, Lucija and Kikelj, Danijel
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2010, Volume 53, Issue 18, pp. 6584 - 6594
We have designed, synthesized, and evaluated 5-benzylidenerhodanine- and 5-benzylidenethiazolidine-2,4-dione-based compounds as inhibitors of bacterial enzyme... 
D-GLUTAMIC ACID | ADDING ENZYME | CHEMISTRY, MEDICINAL | PEPTIDOGLYCAN BIOSYNTHESIS | CELL-WALL | L-ALANINE | RHODANINE | ESCHERICHIA-COLI | PURIFICATION | POTENTIAL INHIBITORS | DERIVATIVES | Thiazolidines - chemical synthesis | Gram-Positive Bacteria - drug effects | Rhodanine - chemical synthesis | Stereoisomerism | Crystallography, X-Ray | Structure-Activity Relationship | Thiazolidinediones - chemistry | Glutamic Acid - chemical synthesis | Rhodanine - analogs & derivatives | Rhodanine - pharmacology | Anti-Bacterial Agents - chemistry | Molecular Structure | Escherichia coli Proteins - antagonists & inhibitors | Thiazolidinediones - pharmacology | Thiazolidines - pharmacology | Thiazolidines - chemistry | Catalytic Domain | Glutamic Acid - pharmacology | Rhodanine - chemistry | Models, Molecular | Anti-Bacterial Agents - chemical synthesis | Gram-Negative Bacteria - drug effects | Glutamic Acid - analogs & derivatives | Thiazolidinediones - chemical synthesis | Protein Binding | Anti-Bacterial Agents - pharmacology | Peptide Synthases - antagonists & inhibitors | Glutamic Acid - chemistry
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14. Full Text Peptide‐Decorated Dendrimers and Their Bioapplications
by Wan, Jingjing and Alewood, Paul F
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2016, Volume 55, Issue 17, pp. 5124 - 5134
Peptide‐decorated dendrimers (PDDs) are a class of spherical, regular, branched polymers that are modified by peptides covalently attached to their surface.... 
peptides | drug delivery | dendrimers | conjugation chemistry | multivalency | DRUG-DELIVERY | RGD PEPTIDES | NATIVE CHEMICAL LIGATION | DENDRITIC POLYGLYCEROL | SYNTHETIC STRATEGIES | FREE CLICK CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | CELL MICROENVIRONMENTS | BIOMEDICAL APPLICATIONS | THIAZOLIDINE LINKAGES | TARGETED DELIVERY | Biomimetic Materials - chemical synthesis | Gene Transfer Techniques | Peptides - chemistry | Biocompatible Materials - chemistry | Humans | Models, Molecular | Polylysine - chemistry | Dendrimers - chemical synthesis | Drug Carriers - chemical synthesis | Drug Carriers - chemistry | Chemistry Techniques, Synthetic - methods | Biocompatible Materials - chemical synthesis | Animals | Peptides - chemical synthesis | Polylysine - chemical synthesis | Radionuclide Imaging - methods | Dendrimers - chemistry | Drug Delivery Systems - methods | Biomimetic Materials - chemistry | Optical Imaging - methods | Peptides | Dendrimers | Biological products | Surgical implants | L-lysine | Innovations | Activation | Drug development | Biomaterials | Covalence | Biomedical materials | Poly-L-lysine | Lysine | Polymers | Chemical synthesis
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15. Full Text Copper-Catalyzed Three-Component Synthesis of Benzothiazolethiones from o‑Iodoanilines, Isocyanide, and Potassium Sulfide
by Dang, Pan and Zeng, Weilan and Liang, Yun
Organic Letters, ISSN 1523-7060, 01/2015, Volume 17, Issue 1, pp. 34 - 37
An efficient copper catalyzed strategy for the synthesis of a variety of benzothiazolethione derivatives has been developed. In the presence of CuCl, the... 
Benzothiazoles - chemical synthesis | Combinatorial Chemistry Techniques | Copper - chemistry | Thiazolidines - chemical synthesis | Cyanides - chemistry | Sulfides - chemistry | Benzothiazoles - chemistry | Molecular Structure | Aniline Compounds - chemistry | Catalysis | Thiazolidines - chemistry | Potassium - chemistry
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16. Full Text Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones
by Havrylyuk, Dmytro and Zimenkovsky, Borys and Vasylenko, Olexandr and Day, Craig W and Smee, Donald F and Grellier, Philippe and Lesyk, Roman
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2013, Volume 66, pp. 228 - 237
A series of novel 5-pyrazoline substituted 4-thiazolidinones have been synthesized. Target compounds were evaluated for their anticancer activity within DTP... 
Synthesis | Antitrypanosomal activity | Pyrazolines | 4-Thiazolidinones | Anticancer activity | Antiviral activity | CHEMISTRY, MEDICINAL | TRYPANOSOMA-CRUZI | ANTICANCER ACTIVITY EVALUATION | ACIDS DERIVATIVES | ANTI-HIV AGENTS | ANTITUMOR-ACTIVITY | ANTI-HIV-1 AGENTS | MEDICINAL CHEMISTRY | IN-VITRO | INHIBITORS | DRUG SCREEN | Antiviral Agents - pharmacology | Chemistry Techniques, Synthetic | Thiazolidines - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Viruses - drug effects | Antiprotozoal Agents - chemistry | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Antiprotozoal Agents - pharmacology | Trypanosoma brucei brucei - drug effects | Pyrazoles - chemistry | Antiviral Agents - chemistry | Antiviral Agents - chemical synthesis | Cell Line, Tumor | Antiprotozoal Agents - chemical synthesis | Antineoplastic Agents - pharmacology | Thiazolidines - pharmacology | Thiazolidines - chemistry | Antiviral agents | Health aspects | Analysis | Leukemia | Life Sciences | Microbiology and Parasitology | Chemical Sciences
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