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1. Full Text In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis
by Benoit Lechartier and Ruben C. Hartkoorn and Stewart T. Cole
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2012, Volume 56, Issue 11, pp. 5790 - 5793
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DRUGS | SYNERGY | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | ANTAGONISM | CANDIDATES | SQ109 | Fluoroquinolones | Isoniazid - pharmacology | Ethambutol - pharmacology | Aza Compounds - pharmacology | Moxifloxacin | Mycobacterium tuberculosis - drug effects | Quinolines - pharmacology | Microbial Sensitivity Tests | Spiro Compounds - chemical synthesis | Thiazines - pharmacology | Meropenem | Adamantane - analogs & derivatives | Adamantane - pharmacology | Nitroimidazoles - pharmacology | Antitubercular Agents - pharmacology | Microbial Viability | Thienamycins - pharmacology | Thiazines - chemical synthesis | Ethylenediamines - pharmacology | Drug Synergism | Diarylquinolines | Rifampin - pharmacology | Drug Combinations | Spiro Compounds - pharmacology | Mycobacterium tuberculosis - growth & development | Experimental Therapeutics
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2. Full Text Silver- and fluoride-containing mesoporous bioactive glasses versus commonly used antibiotics: Activity against multidrug-resistant bacterial strains isolated from patients with burns
by Gholipourmalekabadi, M and Sameni, M and Hashemi, A and Zamani, F and Rostami, A and Mozafari, M
Burns, ISSN 0305-4179, 2015, Volume 42, Issue 1, pp. 131 - 140
Graphical abstract 
Critical Care | Bioactive glass | Silver | Antibacterial activity | Fluoride | Wound healing | THIN-FILMS | SYSTEM | SURGERY | SOL-GEL METHOD | CELLS | ANTIBACTERIAL | METALLO-BETA-LACTAMASES | WOUND INFECTIONS | DERMATOLOGY | IN-VITRO | GENE | PSEUDOMONAS-AERUGINOSA | CRITICAL CARE MEDICINE | NIH 3T3 Cells | Ceftazidime - pharmacology | Humans | Tobramycin - pharmacology | Glass | Ceftriaxone - pharmacology | Aztreonam - pharmacology | Microbial Sensitivity Tests | Piperacillin - pharmacology | Gentamicins - pharmacology | Drug Resistance, Multiple, Bacterial | Cephalosporins - pharmacology | Penicillanic Acid - analogs & derivatives | Penicillanic Acid - pharmacology | Cell Survival - drug effects | Silver - pharmacology | Burns - microbiology | Ciprofloxacin - pharmacology | Pseudomonas aeruginosa - drug effects | Thienamycins - pharmacology | Amikacin - pharmacology | Carbenicillin - pharmacology | Imipenem - pharmacology | Fluorides - pharmacology | Animals | Wound Infection - microbiology | Anti-Bacterial Agents - pharmacology | Mice | Drug resistance in microorganisms | Bacteria | Usage | Antibacterial agents | Index Medicus
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3. Full Text Evaluation of Double- and Triple-Antibiotic Combinations for VIM- and NDM-Producing Klebsiella pneumoniae by In Vitro Time-Kill Experiments
by T. Tängdén and R. A. Hickman and P. Forsberg and P. Lagerbäck and C. G. Giske and O. Cars
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 03/2014, Volume 58, Issue 3, pp. 1757 - 1762
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INFECTIONS | PHARMACOKINETICS | BETA-LACTAMASE | FOSFOMYCIN | RESISTANCE | CARBAPENEMASES | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CRITICALLY-ILL PATIENTS | POLYMYXIN-B | EPIDEMIOLOGY | ENTEROBACTERIACEAE | Klebsiella pneumoniae - drug effects | Minocycline - pharmacology | Minocycline - analogs & derivatives | Aztreonam - pharmacology | Microbial Sensitivity Tests | Colistin - pharmacology | Aminoglycosides - administration & dosage | Drug Resistance, Multiple, Bacterial | Vancomycin - pharmacology | Minocycline - administration & dosage | Rifampin - administration & dosage | beta-Lactamases - metabolism | Vancomycin - administration & dosage | Thienamycins - administration & dosage | Fosfomycin - pharmacology | Ciprofloxacin - pharmacology | Colistin - administration & dosage | Thienamycins - pharmacology | Drug Synergism | Daptomycin - pharmacology | Aztreonam - administration & dosage | Fosfomycin - administration & dosage | Ciprofloxacin - administration & dosage | Anti-Bacterial Agents - pharmacology | Rifampin - pharmacology | Aminoglycosides - pharmacology | In Vitro Techniques | Anti-Bacterial Agents - administration & dosage | Daptomycin - administration & dosage | Experimental Therapeutics
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4. Full Text Carbapenems: Past, Present, and Future
by Krisztina M. Papp-Wallace and Andrea Endimiani and Magdalena A. Taracila and Robert A. Bonomo
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2011, Volume 55, Issue 11, pp. 4943 - 4960
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QUATERNARY AMMONIUM CARBAPENEMS | MULTIDRUG EFFLUX PUMP | GRAM-NEGATIVE BACTERIA | METALLO-BETA-LACTAMASE | OUTER-MEMBRANE PROTEIN | PSEUDOMONAS-AERUGINOSA | PENICILLIN-BINDING PROTEINS | RESISTANT ACINETOBACTER-BAUMANNII | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | VERONII BV SOBRIA | IN-VITRO ACTIVITY | Imipenem - therapeutic use | Humans | beta-Alanine - therapeutic use | Thienamycins - pharmacology | Imipenem - pharmacology | Anti-Bacterial Agents - therapeutic use | beta-Lactams - pharmacology | Carbapenems - pharmacology | Carbapenems - therapeutic use | beta-Alanine - pharmacology | Anti-Bacterial Agents - pharmacology | Cilastatin - therapeutic use | beta-Alanine - analogs & derivatives | beta-Lactams - therapeutic use | Drug Combinations | Cilastatin - pharmacology | Thienamycins - therapeutic use | Minireview
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5. Full Text The development of drugs against Acanthamoeba infections
by Siddiqui, Ruqaiyyah and Aqeel, Yousuf and Khan, Naveed Ahmed
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2016, Volume 60, Issue 11, pp. 6441 - 6450
For the past several decades, there has been little improvement in the morbidity and mortality associated with Acanthamoeba keratitis and Acanthamoeba... 
Polymyxin B - pharmacology | Biguanides - pharmacology | Acanthamoeba - metabolism | Cefazolin - pharmacology | Infectious Encephalitis - parasitology | Acanthamoeba - drug effects | Lipopeptides - pharmacology | Humans | Amphotericin B - pharmacology | Chlorhexidine - pharmacology | Acanthamoeba Keratitis - drug therapy | Thienamycins - pharmacology | Azoles - pharmacology | Infectious Encephalitis - drug therapy | Antiprotozoal Agents - pharmacology | Natamycin - pharmacology | Acanthamoeba - growth & development | Animals | Acanthamoeba Keratitis - parasitology | Antiprotozoal Agents - chemical synthesis | Echinocandins - pharmacology
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6. Full Text Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis
by Claudia Sala and Neeraj Dhar and Ruben C. Hartkoorn and Ming Zhang and Young Hwan Ha and Patricia Schneider and Stewart T. Cole
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2010, Volume 54, Issue 10, pp. 4150 - 4158
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PA-824 | PERSISTENCE | ATP HOMEOSTASIS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INFECTION | LATENCY | ABSENCE | Fluoroquinolones | Isoniazid - pharmacology | Nitroimidazoles - pharmacology | Streptomycin - pharmacology | Antitubercular Agents - pharmacology | Aza Compounds - pharmacology | Meropenem | Moxifloxacin | Rifampin - pharmacology | Thienamycins - pharmacology | Mycobacterium tuberculosis - drug effects | Quinolines - pharmacology | Susceptibility
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7. Full Text In vitro synergistic activity of antimicrobial agents in combination against clinical isolates of Colistin-resistant Acinetobacter baumannii
by Bae, Seongman and Kim, Min-Chul and Park, Su-Jin and Kim, Hee Sueng and Sung, Heungsup and Kim, Mi-Na and Kim, Sung-Han and Lee, Sang-Oh and Choi, Sang-Ho and Woo, Jun Hee and Kim, Yang Soo and Chong, Yong Pil
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2016, Volume 60, Issue 11, pp. 6774 - 6779
Emerging resistance to colistin in clinical Acinetobacter baumannii isolates is of growing concern. Since current treatment options for these strains are... 
STRAINS | INFECTIONS | TIGECYCLINE | THERAPEUTIC OPTIONS | PSEUDOMONAS-AERUGINOSA | SUSCEPTIBILITIES | CARBAPENEMASES | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS | RIFAMPICIN | NEPHROTOXICITY | Pneumonia, Bacterial - microbiology | Ceftazidime - pharmacology | Acinetobacter Infections - pathology | Humans | Aztreonam - pharmacology | Thienamycins - pharmacology | Bacteremia - microbiology | Drug Synergism | Microbial Sensitivity Tests | Colistin - pharmacology | Vancomycin - pharmacology | Teicoplanin - pharmacology | Acinetobacter baumannii - isolation & purification | Anti-Bacterial Agents - pharmacology | Retrospective Studies | Rifampin - pharmacology | Acinetobacter baumannii - drug effects | Acinetobacter baumannii - growth & development | Bacteremia - pathology | Drug Resistance, Multiple, Bacterial - drug effects | Pneumonia, Bacterial - pathology | Drug Combinations | Acinetobacter Infections - microbiology
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8. Full Text An immunocompromised child with bloodstream infection caused by two Escherichia coli strains, one harboring NDM-5 and the other harboring OXA-48-like carbapenemase
by Hasassri, M. Earth and Boyce, Thomas G and Norgan, Andrew and Cunningham, Scott A and Jeraldo, Patricio R and Weissman, Scott and Patel, Robin and Banerjee, Ritu and Pogue, Jason M and Kaye, Keith S
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2016, Volume 60, Issue 6, pp. 3270 - 3275
We describe a 16-year-old neutropenic patient from the Middle East with bloodstream infection caused by two carbapenemase-producing Escherichia coli isolates... 
MORTALITY | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | KLEBSIELLA-PNEUMONIAE | Penicillanic Acid - pharmacology | Escherichia coli - enzymology | Escherichia coli - drug effects | Humans | Tobramycin - pharmacology | Bacterial Proteins - genetics | Ciprofloxacin - pharmacology | Aztreonam - pharmacology | Thienamycins - pharmacology | Amikacin - pharmacology | Piperacillin - pharmacology | beta-Lactams - pharmacology | beta-Lactamases - genetics | Escherichia coli - genetics | Gentamicins - pharmacology | Adolescent | Bacterial Proteins - metabolism | Female | Anti-Bacterial Agents - pharmacology | Immunocompromised Host | beta-Lactamases - metabolism | Penicillanic Acid - analogs & derivatives
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9. Full Text Antibiotic selection of Escherichia coli sequence type 131 in a mouse intestinal colonization model
by Hertz, Frederik Boetius and Løbner-Olesen, Anders and Frimodt-Møller, Niels
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2014, Volume 58, Issue 10, pp. 6139 - 6144
The ability of different antibiotics to select for extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli remains a topic of discussion. In a mouse... 
URINARY-TRACT-INFECTION | STRAINS | IN-VITRO | RISK-FACTORS | ST131 | SUSCEPTIBILITIES | LACTAMASE-PRODUCING ENTEROBACTERIACEAE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | BLOOD-STREAM INFECTIONS | KLEBSIELLA-PNEUMONIAE | E. COLI | Gram-Positive Bacteria - drug effects | Escherichia coli - drug effects | Ciprofloxacin - pharmacology | Cefuroxime - pharmacology | Thienamycins - pharmacology | Clindamycin - pharmacology | Animals | Dicloxacillin - pharmacology | Amdinocillin - pharmacology | Cefotaxime - pharmacology | Ampicillin - pharmacology | Anti-Bacterial Agents - pharmacology | Mice | Penicillins - pharmacology | Experimental Therapeutics
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10. Full Text Penicillin binding protein 1 is important in the compensatory response of Staphylococcus aureus to daptomycin-induced membrane damage and is a potential target for β-lactam-daptomycin synergy
by Berti, Andrew D and Theisen, Erin and Sauer, John-Demian and Nonejuie, Poochit and Olson, Joshua and Pogliano, Joseph and Sakoulas, George and Nizet, Victor and Proctor, Richard A and Rose, Warren E
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2016, Volume 60, Issue 1, pp. 451 - 458
The activity of daptomycin (DAP) against methicillin-resistant Staphylococcus aureus (MRSA) is enhanced in the presence of beta-lactam antibiotics. This effect... 
STRAINS | CELL-DIVISION | IN-VITRO | ANTIBIOTICS | VANCOMYCIN | ANTIBACTERIAL ACTIVITY | PBP1 | RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | WALL-STRESS STIMULON | MODEL | Transcription, Genetic - drug effects | Thienamycins - pharmacokinetics | Cefaclor - pharmacology | Ceftriaxone - pharmacology | Penicillin-Binding Proteins - genetics | Cefoxitin - pharmacology | Imipenem - pharmacokinetics | Protein Isoforms - metabolism | Cell Membrane - metabolism | Drug Therapy, Combination | Methicillin-Resistant Staphylococcus aureus - genetics | Cell Membrane - drug effects | Promoter Regions, Genetic | Methicillin-Resistant Staphylococcus aureus - drug effects | Models, Statistical | Penicillin-Binding Proteins - metabolism | Thienamycins - pharmacology | Imipenem - pharmacology | Drug Synergism | Daptomycin - pharmacology | Methicillin-Resistant Staphylococcus aureus - metabolism | Anti-Bacterial Agents - pharmacokinetics | Daptomycin - pharmacokinetics | Cefotaxime - pharmacology | Anti-Bacterial Agents - pharmacology | Gene Expression Regulation, Bacterial | Nafcillin - pharmacology | Protein Isoforms - genetics
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11. Full Text Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of ampc
by Cabot, Gabriel and Bruchmann, Sebastian and Mulet, Xavier and Zamorano, Laura and Moyá, Bartolomé and Juan, Carlos and Haussler, Susanne and Olivera, Antonio
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 2014, Volume 58, Issue 6, pp. 3091 - 3099
We compared the dynamics and mechanisms of resistance development to ceftazidime, meropenem, ciprofloxacin, and ceftolozane-tazobactam in wild-type (PAO1) and... 
BETA-LACTAM RESISTANCE | HIGH-RISK CLONES | CEPHALOSPORIN CXA-101 | GENETIC-DETERMINANTS | CXA-101 FR264205 | CLINICAL STRAINS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | MECHANISMS | DRUG-RESISTANCE | CARBAPENEM-RESISTANT | BLOOD-STREAM INFECTIONS | Penicillanic Acid - pharmacology | Ceftazidime - pharmacology | Bacterial Proteins - genetics | Pseudomonas aeruginosa - drug effects | Thienamycins - pharmacology | Pseudomonas Infections - microbiology | Imipenem - pharmacology | Microbial Sensitivity Tests | Piperacillin - pharmacology | beta-Lactamases - genetics | Pseudomonas aeruginosa - genetics | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Mutation | beta-Lactamases - metabolism | Cephalosporins - pharmacology | Penicillanic Acid - analogs & derivatives | Mechanisms of Resistance
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12. Full Text Effects of Antibiotics on Shiga Toxin 2 Production and Bacteriophage Induction by Epidemic Escherichia coli O104:H4 Strain
by Martina Bielaszewska and Evgeny A. Idelevich and Wenlan Zhang and Andreas Bauwens and Frieder Schaumburg and Alexander Mellmann and Georg Peters and Helge Karch
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2012, Volume 56, Issue 6, pp. 3277 - 3282
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IN-VITRO | INFECTIONS | HEMOLYTIC-UREMIC SYNDROME | DIARRHEA | GERMANY | RIFAXIMIN | O157-H7 | RISK | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | OUTBREAK | EXPOSURE | Minocycline - pharmacology | Bacteriophages - drug effects | Escherichia coli - drug effects | Minocycline - analogs & derivatives | Ciprofloxacin - pharmacology | Shiga Toxin 2 - metabolism | Thienamycins - pharmacology | Azithromycin - pharmacology | Escherichia coli - virology | Rifamycins - pharmacology | Chloramphenicol - pharmacology | Escherichia coli - metabolism | Anti-Bacterial Agents - pharmacology | Clinical Therapeutics
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13. Full Text Ceftazidime-avibactam activity against multidrug-resistant Pseudomonas aeruginosa isolated in U.S. Medical Centers in 2012 and 2013
by Sader, Helio S and Castanheira, Mariana and Mendes, Rodrigo E and Flamm, Robert K and Farrell, David J and Jones, Ronald N
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2015, Volume 59, Issue 6, pp. 3656 - 3659
Pseudomonas aeruginosa isolates (n = 3,902) from 75 U.S. medical centers were tested against ceftazidime-avibactam and comparator agents by the reference broth... 
HOSPITALS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | MECHANISMS | IN-VITRO ACTIVITY | Azabicyclo Compounds - pharmacology | Microbial Sensitivity Tests | Penicillanic Acid - pharmacology | Piperacillin - pharmacology | Ceftazidime - pharmacology | United States | Anti-Bacterial Agents - pharmacology | Pseudomonas aeruginosa - drug effects | Thienamycins - pharmacology | Penicillanic Acid - analogs & derivatives | Epidemiology and Surveillance
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