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Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2015, Volume 34, Issue 3, pp. 307 - 325
The protein kinase PINK 1 was recently shown to phosphorylate ubiquitin (Ub) on Ser65, and phosphoUb activates the E3 ligase Parkin allosterically. Here, we... 
PINK1 | phosphorylation | deubiquitinase | ubiquitin | Parkin | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | 63-LINKED POLYUBIQUITIN CHAINS | DAMAGED MITOCHONDRIA | CELL BIOLOGY | E3 LIGASE | ACTIVATE PARKIN | BINDING PROTEINS | CROSS-REACTIVITY | CONJUGATING ENZYME | REVEALS | Phosphorylation - physiology | Ubiquitin-Specific Proteases - genetics | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Mitochondrial Proteins - genetics | Phosphoproteins - metabolism | Polyubiquitin - genetics | Allosteric Regulation - physiology | Mitochondrial Proteins - metabolism | Protein Multimerization - physiology | Ubiquitin Thiolesterase - metabolism | TNF Receptor-Associated Factor 6 - genetics | Ubiquitination - physiology | Ubiquitin-Specific Proteases - metabolism | Polyubiquitin - metabolism | Protein Structure, Tertiary | Endopeptidases - metabolism | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin-Protein Ligases - metabolism | Serine - genetics | Ubiquitin-Conjugating Enzymes - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Ubiquitin Thiolesterase - genetics | Serine - metabolism | Hydrolysis | Transcription Factors - metabolism | Endopeptidases - genetics | Ubiquitin-Conjugating Enzymes - metabolism | Adaptor Proteins, Signal Transducing - genetics | TNF Receptor-Associated Factor 6 - metabolism | Thiolester Hydrolases - genetics | Thiolester Hydrolases - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Enzymes | Phosphorylation | Kinases | Crystal structure | Index Medicus
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2009, Volume 11, Issue 6, pp. 705 - 16
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2015, Volume 17, Issue 2, pp. 160 - 169
Journal Article
Biochemistry, ISSN 0006-2960, 10/2013, Volume 52, Issue 43, pp. 7559 - 7574
Journal Article
Nature, ISSN 0028-0836, 12/2015, Volume 528, Issue 7582, pp. 422 - 426
Journal Article
by Xiong, H and Ni, Z and He, J and Jiang, S and Li, X and He, J and Gong, W and Zheng, L and Chen, S and Li, B and Zhang, N and Lyu, X and Huang, G and Chen, B and Zhang, Y and He, F
Oncogene, ISSN 0950-9232, 06/2017, Volume 36, Issue 25, pp. 3528 - 3540
Considerable evidences have shown that autophagy has an important role in tumor chemoresistance. However, it is still unknown whether the lncRNA HULC (highly... 
ACTIVATION | USP22 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | PROLIFERATION | CANCER | CELL BIOLOGY | MAINTENANCE | LONG NONCODING RNA | ONCOLOGY | GENETICS & HEREDITY | CHEMORESISTANCE | SUPPRESSES | CONTRIBUTES | Sirtuin 1 - metabolism | Humans | Drug Resistance, Neoplasm | MicroRNAs - metabolism | Neoplasm Proteins - metabolism | Autophagy | RNA, Neoplasm - metabolism | Sirtuin 1 - genetics | Carcinoma, Hepatocellular - drug therapy | Carcinoma, Hepatocellular - genetics | Antineoplastic Agents - pharmacology | Enzyme Stability - genetics | Gene Expression Regulation, Neoplastic - drug effects | 3' Untranslated Regions | Neoplasm Proteins - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | RNA, Long Noncoding - genetics | Hep G2 Cells | Liver Neoplasms - metabolism | RNA, Neoplasm - genetics | MicroRNAs - genetics | Thiolester Hydrolases - genetics | Thiolester Hydrolases - metabolism | RNA, Long Noncoding - metabolism | Carcinoma, Hepatocellular - metabolism | Autophagy (Cytology) | Care and treatment | RNA | Development and progression | Genetic aspects | Hepatoma | Gene expression | Health aspects | Ubiquitin | Peptidase | 5-Fluorouracil | MiRNA | Chemoresistance | Hepatocellular carcinoma | mRNA | SIRT1 protein | Proteins | Liver cancer | Chemotherapy | Oxaliplatin | Phagocytosis | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 502, Issue 7472, pp. 571 - 574
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2014, Volume 289, Issue 49, pp. 33741 - 33753
Journal Article