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Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 03/2014, Volume 12, Issue 3, pp. 320 - 328
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2013, Volume 19, Issue 4, pp. 446 - 451
Journal Article
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 10/2013, Volume 76, Issue 4, pp. 573 - 579
Numerous pre‐clinical studies have implicated endothelin‐1 in the pathogenesis of diabetic and non‐diabetic chronic kidney disease ( CKD ). Renal endothelin‐1... 
endothelin | chronic kidney disease | receptor | antagonist | diabetes | Chronic kidney disease | Endothelin | Antagonist | Diabetes | Receptor | A RECEPTOR ANTAGONISM | CHRONIC-HEMODIALYSIS PATIENTS | PULMONARY-HYPERTENSION | ANGIOTENSIN-II | B-RECEPTOR | BLOOD-PRESSURE | ARTERIOVENOUS-FISTULA | NITRIC-OXIDE | PLASMA ENDOTHELIN | PHARMACOLOGY & PHARMACY | CHRONIC-RENAL-FAILURE | Endothelin-1 - antagonists & inhibitors | Thiophenes - therapeutic use | Renal Insufficiency, Chronic - etiology | Thiophenes - adverse effects | Humans | Diabetic Nephropathies - drug therapy | Thiophenes - administration & dosage | Renal Insufficiency, Chronic - drug therapy | Dose-Response Relationship, Drug | Renal Insufficiency, Chronic - metabolism | Pyridines - adverse effects | Endothelin A Receptor Antagonists | Pyridines - therapeutic use | Pyridines - administration & dosage | Pyrimidines - administration & dosage | Diabetic Nephropathies - metabolism | Kidney Failure, Chronic - drug therapy | Treatment Outcome | Clinical Trials as Topic | Endothelin B Receptor Antagonists | Isoxazoles - administration & dosage | Kidney Failure, Chronic - metabolism | Animals | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Isoxazoles - therapeutic use | Isoxazoles - adverse effects | Kidney Failure, Chronic - etiology | Renal Dialysis | Development and progression | Chronic kidney failure | Reviews
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37097
We have previously shown that peroxisome proliferator activating receptor beta/delta (PPAR beta/delta is overexpressed in psoriasis. PPAR beta/delta is not... 
DELTA ANTAGONIST | GAMMA AGONISTS | CELLS | ACID | MULTIDISCIPLINARY SCIENCES | GSK3787 | IDENTIFICATION | EXPRESSION | Benzamides - pharmacokinetics | Skin - metabolism | Humans | Thiophenes - administration & dosage | PPAR gamma - metabolism | Benzamides - administration & dosage | Psoriasis - genetics | Psoriasis - pathology | Psoriasis - metabolism | Ointments | Skin - pathology | Disease Models, Animal | PPAR gamma - genetics | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Psoriasis - drug therapy | PPAR-beta - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Skin Absorption | Recombinant Proteins - genetics | Sulfones - pharmacokinetics | PPAR-beta - genetics | Thiophenes - pharmacokinetics | Animals | PPAR gamma - antagonists & inhibitors | PPAR-beta - antagonists & inhibitors | Mice | Administration, Topical | Skin - drug effects | Sulfones - administration & dosage | Animal models | Pathogenesis | Multiple myeloma | Antagonists | Arthritis | Activation | Metastasis | Stomach cancer | Vehicles | Signal transduction | Atherosclerosis | Skin diseases | Life sciences | Inhibition | Growth factors | Medical research | Psoriasis | Dermatology | Research & development--R&D | Rheumatology | Transgenic mice | Exploration | Mass spectroscopy | Epidermis | Data processing | Inflammation | Liquid chromatography | Dentistry | Metabolism | High-performance liquid chromatography | Medicine | Signaling | Chemistry | Nursing | Acids | Ligands | Skin | Peroxisome proliferator-activated receptors | Topical application | Mass spectrometry | High performance liquid chromatography | Research & development | R&D
Journal Article
American Heart Journal, ISSN 0002-8703, 2014, Volume 169, Issue 4, pp. 472 - 478.e5
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2016, Volume 26, Issue 19, pp. 4684 - 4686
Journal Article
Chest, ISSN 0012-3692, 2012, Volume 141, Issue 1, pp. 20 - 26
Journal Article