X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1652) 1652
Book Chapter (29) 29
Publication (24) 24
Dissertation (6) 6
Conference Proceeding (2) 2
Magazine Article (1) 1
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1187) 1187
pharmacogenetics (763) 763
azathioprine (697) 697
index medicus (657) 657
thiopurine methyltransferase (593) 593
thiopurine s-methyltransferase (527) 527
pharmacology & pharmacy (522) 522
6-mercaptopurine (503) 503
female (475) 475
male (474) 474
methyltransferases - genetics (393) 393
inflammatory-bowel-disease (340) 340
adult (330) 330
genotype (317) 317
gastroenterology & hepatology (314) 314
crohns-disease (281) 281
acute lymphoblastic-leukemia (278) 278
mercaptopurine (275) 275
inflammatory bowel disease (274) 274
therapy (274) 274
middle aged (241) 241
methyltransferases - metabolism (238) 238
azathioprine - therapeutic use (232) 232
child (227) 227
immunosuppressive agents - therapeutic use (220) 220
azathioprine - adverse effects (213) 213
toxicity (208) 208
polymorphism, genetic (207) 207
adolescent (206) 206
inflammatory bowel diseases - drug therapy (194) 194
polymorphism (184) 184
thiopurine methyltransferase activity (176) 176
immunosuppressive agents - adverse effects (167) 167
treatment outcome (167) 167
mercaptopurine - therapeutic use (162) 162
tpmt (162) 162
children (159) 159
oncology (156) 156
pharmacogenomics (151) 151
thiopurines (151) 151
animals (150) 150
crohn's disease (147) 147
aged (146) 146
genetic-polymorphism (146) 146
phenotype (146) 146
alleles (143) 143
metabolites (140) 140
metabolism (137) 137
thiopurine (136) 136
s-methyltransferase (134) 134
child, preschool (131) 131
mercaptopurine - adverse effects (125) 125
crohn disease - drug therapy (121) 121
6-thioguanine (120) 120
biochemistry & molecular biology (120) 120
ulcerative colitis (120) 120
precursor cell lymphoblastic leukemia-lymphoma - drug therapy (119) 119
genetic aspects (117) 117
research (117) 117
azathioprine therapy (115) 115
mutation (113) 113
retrospective studies (113) 113
enzymes (109) 109
leukemia (107) 107
methyltransferase (106) 106
thioguanine (106) 106
inflammatory bowel diseases (104) 104
pediatrics (102) 102
cancer (101) 101
analysis (97) 97
azathioprine - administration & dosage (97) 97
mercaptopurine - metabolism (97) 97
mercaptopurine - administration & dosage (94) 94
pharmacokinetics (94) 94
care and treatment (92) 92
deficiency (92) 92
risk factors (91) 91
young adult (91) 91
methotrexate (90) 90
polymorphisms (90) 90
population (90) 90
hematology (88) 88
physiological aspects (87) 87
drug therapy (86) 86
pharmacology (86) 86
ulcerative-colitis (86) 86
drugs (85) 85
genetic variation (85) 85
adverse drug-reactions (83) 83
genetics & heredity (83) 83
patients (83) 83
precursor cell lymphoblastic leukemia-lymphoma - genetics (82) 82
toxicology (82) 82
immunosuppressive agents - administration & dosage (81) 81
myelosuppression (81) 81
methylation (79) 79
polymorphism, single nucleotide (79) 79
health aspects (78) 78
medicine, general & internal (78) 78
gene frequency (77) 77
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1630) 1630
Spanish (27) 27
French (21) 21
German (19) 19
Japanese (6) 6
Polish (4) 4
Korean (3) 3
Russian (3) 3
Chinese (2) 2
Turkish (2) 2
Croatian (1) 1
Hungarian (1) 1
Portuguese (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Clinical Gastroenterology, ISSN 0192-0790, 11/2010, Volume 44, Issue 10, pp. e242 - e248
...) during azathioprine (AZA) or 6-mercaptopurine (6–MP) treatment. The purpose of this study was to investigate the relative risk of the thiopurine methyltransferase (TPMT... 
Inflammatory bowel disease | Thiopurine methyltransferase | 6-mercaptopurine | Leukopenia | Azathioprine | S-METHYLTRANSFERASE | azathioprine | ADVERSE DRUG-REACTIONS | inflammatory bowel disease | thiopurine methyltransferase | leukopenia | POLYMORPHISMS | THERAPY | INOSINE TRIPHOSPHATE PYROPHOSPHATASE | GENE | FREQUENCY | PHARMACOGENETICS | GASTROENTEROLOGY & HEPATOLOGY | AZATHIOPRINE TOXICITY | Humans | Methyltransferases - metabolism | Asian Continental Ancestry Group - genetics | Methyltransferases - genetics | Pyrophosphatases - genetics | Leukopenia - genetics | Male | Chromatography, High Pressure Liquid | Young Adult | Tandem Mass Spectrometry | Anti-Inflammatory Agents - adverse effects | Inflammatory Bowel Diseases - enzymology | Inflammatory Bowel Diseases - genetics | Leukopenia - chemically induced | Adult | Anti-Inflammatory Agents - pharmacokinetics | Female | Retrospective Studies | Gastrointestinal Agents - pharmacokinetics | Mercaptopurine - analogs & derivatives | Mercaptopurine - pharmacokinetics | Republic of Korea | Inflammatory Bowel Diseases - drug therapy | Genetic Predisposition to Disease | Risk Assessment | Leukopenia - ethnology | Risk Factors | Kaplan-Meier Estimate | Mercaptopurine - adverse effects | Proportional Hazards Models | Treatment Outcome | Academic Medical Centers | Chi-Square Distribution | Pyrophosphatases - metabolism | Homozygote | Phenotype | Adolescent | Heterozygote | Gastrointestinal Agents - adverse effects | Inflammatory Bowel Diseases - ethnology
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 06/2008, Volume 380, Issue 1, pp. 120 - 130
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 07/2013, Volume 76, Issue 1, pp. 125 - 136
Journal Article
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 07/2009, Volume 24, Issue 7, pp. 1258 - 1264
.... We examined polymorphism of the thiopurine S‐methyltransferase (TPMT) gene to determine whether the TPMT genotype would be a predictive marker for the development of adverse reactions to AZA. Methods... 
thiopurine S‐methyltransferase | azathioprine | adverse reactions | inflammatory bowel disease | Inflammatory bowel disease | Adverse reactions | Thiopurine S-methyltransferase | Azathioprine | thiopurine S-methyltransferase | CONTROLLED-TRIAL | DRUG-REACTIONS | CROHNS-DISEASE | ENZYME-ACTIVITY | 6-MERCAPTOPURINE | MYELOSUPPRESSION | ARTICLE | THERAPY | METABOLITE LEVELS | FREQUENCY | GASTROENTEROLOGY & HEPATOLOGY | Guanine Nucleotides - blood | Predictive Value of Tests | Genetic Testing | Communicable Diseases - chemically induced | Humans | Methyltransferases - genetics | Leukopenia - genetics | Communicable Diseases - genetics | Male | Young Adult | Anti-Inflammatory Agents - adverse effects | Alopecia - genetics | Inflammatory Bowel Diseases - enzymology | Inflammatory Bowel Diseases - genetics | Leukopenia - chemically induced | Adult | Female | Retrospective Studies | Genetic Predisposition to Disease | Liver Diseases - genetics | Thionucleotides - blood | Gene Frequency | Japan | Inflammatory Bowel Diseases - diet therapy | Polymorphism, Genetic | Aminosalicylic Acids - therapeutic use | Asian Continental Ancestry Group | Phenotype | Gastrointestinal Diseases - genetics | Alopecia - chemically induced | Chemical and Drug Induced Liver Injury | Gastrointestinal Agents - adverse effects | Azathioprine - adverse effects | Gastrointestinal Diseases - chemically induced | Inflammatory Bowel Diseases - ethnology | Complications and side effects | Medical research | Gene mutations | Analysis | Gastrointestinal diseases | Medicine, Experimental | Genetic aspects | Index Medicus
Journal Article