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Biochemical Pharmacology, ISSN 0006-2952, 10/2014, Volume 91, Issue 3, pp. 312 - 322
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2007, Volume 50, Issue 6, pp. 1254 - 1265
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2000, Volume 59, Issue 8, pp. 983 - 991
Previous studies from our laboratories have shown that (a) Triapine((TM)) is a potent inhibitor of ribonucleotide reductase activity and (b)... 
antagonists | ribonucleotide reductase | inhibitors | antineoplastic agents combined | L1210 leukemia cells | Triapine 3-AP | inhibition of DNA synthesis | α-( N)-heterocyclic carboxaldehyde thiosemicarbazone | α-(N)-heterocyclic carboxaldehyde thiosemicarbazone | Antineoplastic agents, combined | Inhibition of DNA synthesis | Ribonucleotide reductase, antagonists and inhibitors | Triapine, 3-AP | CELLS | ribonucleotide reductase, antagonists and inhibitors | alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROXYUREA | COMPLEXES | antineoplastic agents, combined | TUMOR | CARBOXALDEHYDE THIOSEMICARBAZONES | IRON | PYRIDINE-2-CARBOXALDEHYDE THIOSEMICARBAZONES | RESISTANT | GROWTH | PHARMACOLOGY & PHARMACY | Hydroxyurea - pharmacology | Neoplasm Transplantation | Humans | Pyridines - pharmacokinetics | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Enzyme Inhibitors - pharmacokinetics | DNA - biosynthesis | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Thiosemicarbazones - pharmacology | Tumor Cells, Cultured | DNA - drug effects | Pyridines - therapeutic use | Leukemia L1210 - drug therapy | KB Cells | Enzyme Inhibitors - pharmacology | Enzyme Inhibitors - therapeutic use | Cell Division - drug effects | Thiosemicarbazones - pharmacokinetics | Animals | Thiosemicarbazones - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Ribonucleotide Reductases - antagonists & inhibitors | Mice | Pyridines - pharmacology | Neoplasms, Experimental - drug therapy | Blood-Brain Barrier
Journal Article
Journal Article
Inorganica Chimica Acta, ISSN 0020-1693, 08/2016, Volume 449, pp. 119 - 126
Unsubstituted isatin-3-thiosemicarbazone formed mononuclear tetrahedral complexes with copper(I) halides whereas the structure of complex revealed that... 
X-ray crystallography | Isatin-N1-ethyl-thiosemicarbazone | Cytotoxicity | Docking | Isatin-N1-methyl-thiosemicarbazone | Copper(I) halide | methyl-thiosemicarbazone | ethyl-thiosemicarbazone | Isatin-N
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 09/2015, Volume 39, Issue 12, pp. 9313 - 9324
Thiosemicarbazones (TSC) have been the subject of a large number of investigations, either because of their pharmacological effects in a wide variety of... 
RIBONUCLEOTIDE REDUCTASE | BIS(THIOSEMICARBAZONE) COMPLEXES | AB-INITIO | 2-ACETYLPYRIDINE THIOSEMICARBAZONES | ANTITUMOR-ACTIVITY | BENZALDEHYDE THIOSEMICARBAZONES | BETA-THIOSEMICARBAZONE | CYTOTOXIC ACTIVITY | HETEROCYCLIC THIOSEMICARBAZONES | CHEMISTRY, MULTIDISCIPLINARY | METAL-COMPLEXES
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 10/2017, Volume 108, Issue Pt A, pp. 53 - 62
Journal Article
Journal Article